The purpose of this study is to verify an 1D multi-plate heat-transfer model estimating the temperature distribution on the interface between polymer electrolyte membrane and catalyst layer at cathode in single cell o...The purpose of this study is to verify an 1D multi-plate heat-transfer model estimating the temperature distribution on the interface between polymer electrolyte membrane and catalyst layer at cathode in single cell of polymer electrolyte fuel cell, which is named as reaction surface in this study, with a 3D numerical simulation model solving many governing equations on the coupling phenomena in the cell. The results from both models/simulations agreed well. The effects of initial operation temperature, flow rate, and relative humidity of supply gas on temperature distribution on the reaction surface were also investigated. It was found in both 1D and 3D simulations that, the temperature rise (i.e., Treact-Tini) of the reaction surface from initial operation temperature at 70℃ was higher than that at 80℃ irrespective of flow rate of supply gas. The effect of relative humidity of supply gas on Treact- Tini near the inlet of the cell was small. Compared to the previous studies conducted under the similar operation conditions, the Treact - Tini calculated by 1D multi-plate heat-transfer model in this study as well as numerical simulation using 3D model was reasonable.展开更多
This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -...This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -3D ) is presented in the Present paper,which is the most suitable one for the dual - structured - aquifer system. An example of Wenyinghu area is shown.By using the 2D-3D model, a satisfied result of the simulated area is achieved.展开更多
Effective management of a river reach requires a sound understanding of flow and sediment transport generated by varying natural and artificial runoff conditions. Flow and sediment transport within the Ning-Meng reach...Effective management of a river reach requires a sound understanding of flow and sediment transport generated by varying natural and artificial runoff conditions. Flow and sediment transport within the Ning-Meng reach of the Yellow River(NMRYR), northern China are controlled by a complex set of factors/processes, mainly including four sets of factors:(1) aeolian sediments from deserts bordering the main stream;(2) inflow of water and sediment from numerous tributaries;(3) impoundment of water by reservoir/hydro-junction; and(4) complex diversion and return of irrigation water. In this study, the 1-D flow & sediment transport model developed by the Yellow River Institute of Hydraulic Research was used to simulate the flow and sediment transport within the NMRYR from 2001 to 2012. All four sets of factors that primarily control the flow and sediment transport mentioned above were considered in this model. Compared to the measured data collected from the hydrological stations along the NMRYR, the simulated flow and sediment transport values were generally acceptable, with relative mean deviation between measured and simulated values of 〈15%. However, simulated sediment concentration and siltation values within two sub-reaches(i.e., Qingtongxia Reservoir to Bayan Gol Hydrological Station and Bayan Gol Hydrological Station to Toudaoguai Hydrological Station) for some periods exhibited relatively large errors(the relative mean deviations between measured and simulated values of 18% and 25%, respectively). These errors are presumably related to the inability to accurately determine the quantity of aeolian sediment influx to the river reach and the inflow of water from the ten ephemeral tributaries. This study may provide some valuable insights into the numerical simulations of flow and sediment transport in large watersheds and also provide a useful model for the effective management of the NMRYR.展开更多
A 3- D free surface flow in open channels based on the Reynolds equations with the k-ε turbulence closure model is presented in this paper. Insted of the 'rigid lid' approximation, the solution of the free su...A 3- D free surface flow in open channels based on the Reynolds equations with the k-ε turbulence closure model is presented in this paper. Insted of the 'rigid lid' approximation, the solution of the free surface equation is implemented in the velocity-pressure iterative procedure on the basis of the conventional SIMPLE method. This model was used to compute the flow in rectangular channels with trenches dredged across the bottom. The velocity, eddy viscosity coefficient, turbulent shear stress, turbulent kinetic energy and elevation of the free surface can be obtained. The computed results are in good agreement with previous experimental data.展开更多
γ-Aminobutyric acid(GABA),plays a key role in all stages of life,also is considered the main inhibitory neurotransmitter.GABA activates two kind of membrane receptors known as GABAA and GABAB,the first one is respo...γ-Aminobutyric acid(GABA),plays a key role in all stages of life,also is considered the main inhibitory neurotransmitter.GABA activates two kind of membrane receptors known as GABAA and GABAB,the first one is responsible to render tonic inhibition by pentameric receptors containing α4-6,β3,δ,or ρ1-3 subunits,they are located at perisynaptic and/or in extrasynaptic regions.The biophysical properties of GABAA tonic inhibition have been related with cellular protection against excitotoxic injury and cell death in presence of excessive excitation.On this basis,GABAA tonic inhibition has been proposed as a potential target for therapeutic intervention of Huntington's disease.Huntington's disease is a neurodegenerative disorder caused by a genetic mutation of the huntingtin protein.For experimental studies of Huntington's disease mouse models have been developed,such as R6/1,R6/2,Hdh Q92,Hdh Q150,as well as YAC128.In all of them,some key experimental reports are focused on neostriatum.The neostriatum is considered as the most important connection between cerebral cortex and basal ganglia structures,its cytology display two pathways called direct and indirect constituted by medium sized spiny neurons expressing dopamine D1 and D2 receptors respectively,they display strong expression of many types of GABAA receptors,including tonic subunits.The studies about of GABAA tonic subunits and Huntington's disease into the neostriatum are rising in recent years,suggesting interesting changes in their expression and localization which can be used as a strategy to delay the cellular damage caused by the imbalance between excitation and inhibition,a hallmark of Huntington's disease.展开更多
To investigate the validity of two dynamic modulus predictive models( Witczak 1-37 A viscosity-based model and Witczak 1-40 D shear modulus-based model) in the context of Jiangsu, and evaluate the effect of differen...To investigate the validity of two dynamic modulus predictive models( Witczak 1-37 A viscosity-based model and Witczak 1-40 D shear modulus-based model) in the context of Jiangsu, and evaluate the effect of different mixture design variables( aggregate gradations, binder type, and volumetric properties) on dynamic modulus E*, asphalt mixtures commonly used in the local surface layer, including Sup-13 and AC-13, are prepared in the laboratory and their dynamic modulus E*values are predicted based on the above mentioned models. The corresponding asphalt tests, including viscosity and dynamic shear modulus tests, are also carried out to obtain the prediction model parameters. The test results showthat binder type and asphalt content have a significant impact on dynamic modulus.There is a good correlation between the E*values based on above two predictive models and the measured E*, while a relatively lower bias can be expected from Witczak 1-37 A model. The test results can be used for the calibration of dynamic modulus with higher accuracy.展开更多
Geochemical analysis of 64 oils sampled from an Ordovician carbonate reservoir in the Tuoputai region was undertaken to study the composition of molecular markers. All the oils have similar geochemical characteristics...Geochemical analysis of 64 oils sampled from an Ordovician carbonate reservoir in the Tuoputai region was undertaken to study the composition of molecular markers. All the oils have similar geochemical characteristics and belong to a single oil family. They are presumed to derive from the same source kitchen and have similar oil charging history. A histogram of homogenization temperatures(Th) of aqueous inclusions in reservoir rocks shows a bimodal distribution pattern, indicating that the Ordovician reservoir has been charged twice. Coupling the measured Th(°C) with the burial and geothermal histories reconstructed using 1D basin modeling, we relate the homogenization temperature to the relevant geological ages: i.e.,425–412 and 9–4 Ma, corresponding to the Middle to Late Silurian and the Miocene to Pliocene, respectively. The oil filling orientation and pathways are traced using molecular indicators related to alkyldibenzothiophenes and benzo[b]naphthothiophenes. The oil charging orientation is from south to north generally. It can be predicted that the Ordovician reservoirs were sourced from a kitchen located to the south of the Tuoputai region, most probably between the Awati and Manjiaer Depressions. Traps located in the southern side of the Tuoputai region, along the oil charging pathways, should therefore be preferred oil exploration targets.展开更多
To meet the increasing :need of fresh water and to improve the water quality of Taihu Lake, water transfer from the Yangtze River was initiated in 2002. This study was performed to investigate the sediment distributi...To meet the increasing :need of fresh water and to improve the water quality of Taihu Lake, water transfer from the Yangtze River was initiated in 2002. This study was performed to investigate the sediment distribution along the river course following water transfer. A rainfall-runoff model was first built to calculate the runoff of the Taihu Basin in 2003. Then, the flow patterns of river networks were simulated using a one-dimensional river network hydrodynamic model. Based on the boundary conditions of the flow in tributaries of the Wangyu River and the water level in Taihu Lake, a one-dimensional hydrodynamic and sediment transport numerical model of the Wangyu River was built to analyze the influences of the inflow rate of the water transfer and the suspended sediment concentration (SSC) of inflow on the sediment transport. The results show that the water transfer inflow rate and SSC of inflow have significant effects on the sediment distribution. The higher the inflow rate or SSC of inflow is, the higher the SSC value is at certain cross-sections along the :river course of water transfer. Higher inflow rate and SSC of inflow contribute to higher sediment deposition per kilometer and sediment thickness. It is also concluded that a sharp decrease of the inflow velocity at the entrance of the Wangyu River on the river course of water transfer induces intense sedimentation at the cross-section near the Changshu hydro-junction. With an increasing distance from the Changshu hydro-junction, the sediment deposition and sedimentation thickness decrease gradually along the river course.展开更多
文摘The purpose of this study is to verify an 1D multi-plate heat-transfer model estimating the temperature distribution on the interface between polymer electrolyte membrane and catalyst layer at cathode in single cell of polymer electrolyte fuel cell, which is named as reaction surface in this study, with a 3D numerical simulation model solving many governing equations on the coupling phenomena in the cell. The results from both models/simulations agreed well. The effects of initial operation temperature, flow rate, and relative humidity of supply gas on temperature distribution on the reaction surface were also investigated. It was found in both 1D and 3D simulations that, the temperature rise (i.e., Treact-Tini) of the reaction surface from initial operation temperature at 70℃ was higher than that at 80℃ irrespective of flow rate of supply gas. The effect of relative humidity of supply gas on Treact- Tini near the inlet of the cell was small. Compared to the previous studies conducted under the similar operation conditions, the Treact - Tini calculated by 1D multi-plate heat-transfer model in this study as well as numerical simulation using 3D model was reasonable.
文摘This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -3D ) is presented in the Present paper,which is the most suitable one for the dual - structured - aquifer system. An example of Wenyinghu area is shown.By using the 2D-3D model, a satisfied result of the simulated area is achieved.
基金financially supported by the National Natural Science Foundation of China(51579113,51309111,51309113)
文摘Effective management of a river reach requires a sound understanding of flow and sediment transport generated by varying natural and artificial runoff conditions. Flow and sediment transport within the Ning-Meng reach of the Yellow River(NMRYR), northern China are controlled by a complex set of factors/processes, mainly including four sets of factors:(1) aeolian sediments from deserts bordering the main stream;(2) inflow of water and sediment from numerous tributaries;(3) impoundment of water by reservoir/hydro-junction; and(4) complex diversion and return of irrigation water. In this study, the 1-D flow & sediment transport model developed by the Yellow River Institute of Hydraulic Research was used to simulate the flow and sediment transport within the NMRYR from 2001 to 2012. All four sets of factors that primarily control the flow and sediment transport mentioned above were considered in this model. Compared to the measured data collected from the hydrological stations along the NMRYR, the simulated flow and sediment transport values were generally acceptable, with relative mean deviation between measured and simulated values of 〈15%. However, simulated sediment concentration and siltation values within two sub-reaches(i.e., Qingtongxia Reservoir to Bayan Gol Hydrological Station and Bayan Gol Hydrological Station to Toudaoguai Hydrological Station) for some periods exhibited relatively large errors(the relative mean deviations between measured and simulated values of 18% and 25%, respectively). These errors are presumably related to the inability to accurately determine the quantity of aeolian sediment influx to the river reach and the inflow of water from the ten ephemeral tributaries. This study may provide some valuable insights into the numerical simulations of flow and sediment transport in large watersheds and also provide a useful model for the effective management of the NMRYR.
文摘A 3- D free surface flow in open channels based on the Reynolds equations with the k-ε turbulence closure model is presented in this paper. Insted of the 'rigid lid' approximation, the solution of the free surface equation is implemented in the velocity-pressure iterative procedure on the basis of the conventional SIMPLE method. This model was used to compute the flow in rectangular channels with trenches dredged across the bottom. The velocity, eddy viscosity coefficient, turbulent shear stress, turbulent kinetic energy and elevation of the free surface can be obtained. The computed results are in good agreement with previous experimental data.
基金the programs for the postdoctoral fellowships-Chilean CONICYT-FONDECYT#3140218,Mexican CONACYT#164978 and DID-UACh S-2015-81Sistema Nacional de Investigadores#58512 to Abraham Rosas-Arellano+2 种基金supported by USACH PhD fellowshipsupported with a PhD fellowship from CONACYT(#299627)FONDECYT grants 1151206 and 1110571 to Maite A.Castro
文摘γ-Aminobutyric acid(GABA),plays a key role in all stages of life,also is considered the main inhibitory neurotransmitter.GABA activates two kind of membrane receptors known as GABAA and GABAB,the first one is responsible to render tonic inhibition by pentameric receptors containing α4-6,β3,δ,or ρ1-3 subunits,they are located at perisynaptic and/or in extrasynaptic regions.The biophysical properties of GABAA tonic inhibition have been related with cellular protection against excitotoxic injury and cell death in presence of excessive excitation.On this basis,GABAA tonic inhibition has been proposed as a potential target for therapeutic intervention of Huntington's disease.Huntington's disease is a neurodegenerative disorder caused by a genetic mutation of the huntingtin protein.For experimental studies of Huntington's disease mouse models have been developed,such as R6/1,R6/2,Hdh Q92,Hdh Q150,as well as YAC128.In all of them,some key experimental reports are focused on neostriatum.The neostriatum is considered as the most important connection between cerebral cortex and basal ganglia structures,its cytology display two pathways called direct and indirect constituted by medium sized spiny neurons expressing dopamine D1 and D2 receptors respectively,they display strong expression of many types of GABAA receptors,including tonic subunits.The studies about of GABAA tonic subunits and Huntington's disease into the neostriatum are rising in recent years,suggesting interesting changes in their expression and localization which can be used as a strategy to delay the cellular damage caused by the imbalance between excitation and inhibition,a hallmark of Huntington's disease.
基金The Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20120092110053)
文摘To investigate the validity of two dynamic modulus predictive models( Witczak 1-37 A viscosity-based model and Witczak 1-40 D shear modulus-based model) in the context of Jiangsu, and evaluate the effect of different mixture design variables( aggregate gradations, binder type, and volumetric properties) on dynamic modulus E*, asphalt mixtures commonly used in the local surface layer, including Sup-13 and AC-13, are prepared in the laboratory and their dynamic modulus E*values are predicted based on the above mentioned models. The corresponding asphalt tests, including viscosity and dynamic shear modulus tests, are also carried out to obtain the prediction model parameters. The test results showthat binder type and asphalt content have a significant impact on dynamic modulus.There is a good correlation between the E*values based on above two predictive models and the measured E*, while a relatively lower bias can be expected from Witczak 1-37 A model. The test results can be used for the calibration of dynamic modulus with higher accuracy.
基金funded by the National Natural Science Foundation of China(Grant No.41272158)the Foundation of State Key Laboratory of Petroleum Resources and Prospecting,China University of Petroleum,Beijing(No.PRP/open-1503)
文摘Geochemical analysis of 64 oils sampled from an Ordovician carbonate reservoir in the Tuoputai region was undertaken to study the composition of molecular markers. All the oils have similar geochemical characteristics and belong to a single oil family. They are presumed to derive from the same source kitchen and have similar oil charging history. A histogram of homogenization temperatures(Th) of aqueous inclusions in reservoir rocks shows a bimodal distribution pattern, indicating that the Ordovician reservoir has been charged twice. Coupling the measured Th(°C) with the burial and geothermal histories reconstructed using 1D basin modeling, we relate the homogenization temperature to the relevant geological ages: i.e.,425–412 and 9–4 Ma, corresponding to the Middle to Late Silurian and the Miocene to Pliocene, respectively. The oil filling orientation and pathways are traced using molecular indicators related to alkyldibenzothiophenes and benzo[b]naphthothiophenes. The oil charging orientation is from south to north generally. It can be predicted that the Ordovician reservoirs were sourced from a kitchen located to the south of the Tuoputai region, most probably between the Awati and Manjiaer Depressions. Traps located in the southern side of the Tuoputai region, along the oil charging pathways, should therefore be preferred oil exploration targets.
基金supported by State Key Development Program of Basic Research of China (Grant No.2010CB429001)the National Natural Science Foundation of China (Grant No. 51009062)the Special Fund of Hydrology-Water Resources and Hydraulic Engineering (Grant No. 2009586812)
文摘To meet the increasing :need of fresh water and to improve the water quality of Taihu Lake, water transfer from the Yangtze River was initiated in 2002. This study was performed to investigate the sediment distribution along the river course following water transfer. A rainfall-runoff model was first built to calculate the runoff of the Taihu Basin in 2003. Then, the flow patterns of river networks were simulated using a one-dimensional river network hydrodynamic model. Based on the boundary conditions of the flow in tributaries of the Wangyu River and the water level in Taihu Lake, a one-dimensional hydrodynamic and sediment transport numerical model of the Wangyu River was built to analyze the influences of the inflow rate of the water transfer and the suspended sediment concentration (SSC) of inflow on the sediment transport. The results show that the water transfer inflow rate and SSC of inflow have significant effects on the sediment distribution. The higher the inflow rate or SSC of inflow is, the higher the SSC value is at certain cross-sections along the :river course of water transfer. Higher inflow rate and SSC of inflow contribute to higher sediment deposition per kilometer and sediment thickness. It is also concluded that a sharp decrease of the inflow velocity at the entrance of the Wangyu River on the river course of water transfer induces intense sedimentation at the cross-section near the Changshu hydro-junction. With an increasing distance from the Changshu hydro-junction, the sediment deposition and sedimentation thickness decrease gradually along the river course.