The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was establishe...The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was established according to their spectroscopic analysis, such as FT-IR, NMR and mass spectroscopy. These new compounds were tested for their antiproliferative activities on seven representative human tumoral cell lines (Huh7 D12, Caco2, MDA-MB231, MDA-MB468, HCT116, PC3 and MCF7) and also on fibroblasts. Among them, only the compounds 6c showed micromolar cytotoxic activity on tumor cell lines (1.8 50 50 > 25 μM). Finally, in silico ADMET studies ware performed to investigate the possibility of using of the identified compound 6c as potential anti-tumor compound.展开更多
An engineering system approach of 2-D cylindrical model of transient mass balance calculations of ozone and other concerned chemicals along with fourteen photolysis, ozone-generating and ozone-depleting chemical react...An engineering system approach of 2-D cylindrical model of transient mass balance calculations of ozone and other concerned chemicals along with fourteen photolysis, ozone-generating and ozone-depleting chemical reaction equations was developed, validated, and used for studying the ozone concentrations, distribution and peak of the layer, ozone depletion and total ozone abundance in the stratosphere. The calculated ozone concentrations and profile at both the Equator and a 60˚N location were found to follow closely with the measured data. The calculated average ozone concentration was within 1% of the measured average, and the deviation of ozone profiles was within 14%. The monthly evolution of stratospheric ozone concentrations and distribution above the Equator was studied with results discussed in details. The influences of slow air movement in both altitudinal and radial directions on ozone concentrations and profile in the stratosphere were explored and discussed. Parametric studies of the influences of gas diffusivities of ozone D<sub>O3</sub> and active atomic oxygen D<sub>O</sub> on ozone concentrations and distributions were also studied and delineated. Having both influences through physical diffusion and chemical reactions, the diffusivity (and diffusion) of atomic oxygen D<sub>O</sub> was found to be more sensitive and important than that of ozone D<sub>O3</sub> on ozone concentrations and distribution. The 2-D ozone model present in this paper for stratospheric ozone and its layer and depletion is shown to be robust, convenient, efficient, and executable for analyzing the complex ozone phenomena in the stratosphere. .展开更多
The authors introduce nonseparable scaling function interpolation and show that its approximation can provide similar convergence properties as scalar wavelet system. Several equivalent statements of accuracy of nonse...The authors introduce nonseparable scaling function interpolation and show that its approximation can provide similar convergence properties as scalar wavelet system. Several equivalent statements of accuracy of nonseparable scaling function are also given. In the numerical experiments, it appears that nonseparable scaling function interpolation has better convergence results than scalar wavelet systems in some cases.展开更多
The sea surface height data volume of the future wide-swath two-dimensional(2D)altimetric satellite is thousands of times greater than that of nadir altimetric satellites.The time complexity of the 2D altimetry mappin...The sea surface height data volume of the future wide-swath two-dimensional(2D)altimetric satellite is thousands of times greater than that of nadir altimetric satellites.The time complexity of the 2D altimetry mapping reaches O(n^(3)).It is challenging to map the global grid products of future 2D altimetric satellites.In this study,to improve the efficiency of global data mapping,a new algorithm called parallel-dynamic interpolation(PA-DI)was designed.Through the use of 2D data segmentation and fine-grained data mosaic methods,the parallel along-track DI processes were accelerated,and a fast and efficient spatial-temporal high-resolution and low-error enhanced mapping method was obtained.As determined from a comparison of the single-threaded DI with the PA-DI,the new algorithm optimized the time complexity from O(n^(3))to O(n^(3)/KL),which improved the mapping efficiency and achieved the expected results.According to the test results of the observing system simulation experiments,the PA-DI algorithm may provide an efficient and reliable method for future wide-swath 2D altimetric satellite mapping.展开更多
2-periodic trigonometric interpolation problems on 2n equidistant nodes and 4n+1 equi- distant nodes are considered respectively.Regularity theorems,fundamental polynomials and convergence rate of the corresponding in...2-periodic trigonometric interpolation problems on 2n equidistant nodes and 4n+1 equi- distant nodes are considered respectively.Regularity theorems,fundamental polynomials and convergence rate of the corresponding interpolations are given here.展开更多
This article studies distributed pose(orientation and position)estimation of leader–follower multi-agent systems over𝜅-layer graphs in 2-D plane.Only the leaders have access to their orientations and position...This article studies distributed pose(orientation and position)estimation of leader–follower multi-agent systems over𝜅-layer graphs in 2-D plane.Only the leaders have access to their orientations and positions,while the followers can measure the relative bearings or(angular and linear)velocities in their unknown local coordinate frames.For the orientation estimation,the local relative bearings are used to obtain the relative orientations among the agents,based on which a distributed orientation estimation algorithm is proposed for each follower to estimate its orientation.For the position estimation,the local relative bearings are used to obtain the position constraints among the agents,and a distributed position estimation algorithm is proposed for each follower to estimate its position by solving its position constraints.Both the orientation and position estimation errors converge to zero asymptotically.A simulation example is given to verify the theoretical results.展开更多
In array signal processing, 2-D spatial-spectrum estimation is required to determine DOA of multiple signals. The circular array of sensors is found to possess several nice properties for DOA estimation of wide-band s...In array signal processing, 2-D spatial-spectrum estimation is required to determine DOA of multiple signals. The circular array of sensors is found to possess several nice properties for DOA estimation of wide-band sources. C. U. Padmini, et al.(1994) had suggested that the frequency-direction ambiguity in azimuth estimation of wide-baud signals received by a uniform linear array (ULA) can be avoided by using a circular array, even without the use of any delay elements. In 2-D spatial-spectrum estimation for wide-band signals, the authors find that it is impossible to avoid the ambiguity in source frequency-elevation angle pairs using a circular array. In this paper, interpolated circular arrays are used to perform 2-D spatial-spectrum estimation for wide-band sources. In the estimation, a large aperture circular array (Υ】λmin/2) is found to possess superior resolution capability and robustness.展开更多
In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficien...In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficients on the input data,a fast and accurate frequency estimator is devised,where only the DFT coefficient with the highest magnitude and its four neighbors are required.Variance analysis is also included to investigate the accuracy of the proposed algorithm.Simulation results are conducted to demonstrate the superiority of the developed scheme,in terms of the estimation performance and computational complexity.展开更多
We study some approximation properties of Lagrange interpolation polynomial based on the zeros of (1-x^2)cosnarccosx. By using a decomposition for f(x) ∈ C^τC^τ+1 we obtain an estimate of ‖f(x) -Ln+2(f, ...We study some approximation properties of Lagrange interpolation polynomial based on the zeros of (1-x^2)cosnarccosx. By using a decomposition for f(x) ∈ C^τC^τ+1 we obtain an estimate of ‖f(x) -Ln+2(f, x)‖ which reflects the influence of the position of the x's and ω(f^(r+1),δ)j,j = 0, 1,... , s,on the error of approximation.展开更多
This paper presents an engineering system approach using a 2D model of conservation of mass to study the dynamics of ozone and concerned chemical species in the stratosphere.By considering all fourteen photolysis,ozon...This paper presents an engineering system approach using a 2D model of conservation of mass to study the dynamics of ozone and concerned chemical species in the stratosphere.By considering all fourteen photolysis,ozone-generating,and-depleting chemical reactions,the model calculated the transient,spatial changes of ozone under different physical-chemical-radiative conditions.Validation against the measured data demonstrated good accuracy,close match of our model with the observed ozone concentrations at both 20°S and 90°N locations.The deviation in the average concentration was less than 1% and in ozone profiles less than 17%.The impacts of various chlorine-(Cl),nitrogen oxides-(NO_(x)),and bromine-(Br)depleting cycles on ozone concentrations and distribution were investigated.The chlorine catalytic depleting cycle was found to exhibit the most significant impact on ozone dynamics,confirming the key role of chlorine in the problem of ozone depletion.Sensitivity analysis was conducted with levels of 25%,50%,100%,200%,and 400% of the baseline value.The combined cycles(Cl+NO_(x)+Br)showed the most significant influence on ozone behavior.The total ozone abundance above the South Pole could decrease by a small 3%,from 281 DU(Dubson Units)to 273 DU for the 25% level,or by a huge thinning of 60%to 114 DU for the 400% concentration level.When the level of chlorine gases increased beyond 200%,it would cause ozone depletion to a level of ozone hole(below 220 DU).The 2D Ozone Model presented in this paper demonstrates robustness,convenience,efficiency,and executability for analyzing complex ozone phenomena in the stratosphere.展开更多
The object in this paper is to consider the problem of existence,uniqueness,explicil representation of(0, 2)-interpolation on the zeros of(1-x^2)P~_(n-1)(x)/x when n is odd,where P_(n-1)denotes Legendre polynomial of ...The object in this paper is to consider the problem of existence,uniqueness,explicil representation of(0, 2)-interpolation on the zeros of(1-x^2)P~_(n-1)(x)/x when n is odd,where P_(n-1)denotes Legendre polynomial of degree n-1,and the problem of convergence of interpolatory polynomials.展开更多
We discuss the definition and effectiveness of a Padé-type approximation to 2π-periodic finite Baire measures on [-π,π]. In the first two sections we recall the definitions and basic properties of the Padr...We discuss the definition and effectiveness of a Padé-type approximation to 2π-periodic finite Baire measures on [-π,π]. In the first two sections we recall the definitions and basic properties of the Padré-type approximants to harmonic functions in the unit disk and to L p -functions on the unit circle. Section 3 deals with the extension of these definitions and properties to a finite 2π-periodic Baire measure. Finally, section 4 is devoted to a study of the convergence of a sequence of such approximants, in the weak star topology of measures.展开更多
The object of this paper is to show regularity of(0,1,...,r-2,r) interpolation on the set obtained by projecting vertically the zeros of (1-x2)pn(x)(λ≥1/2)onto the unit circle,where Pn(x)stands for the nth ultrasphe...The object of this paper is to show regularity of(0,1,...,r-2,r) interpolation on the set obtained by projecting vertically the zeros of (1-x2)pn(x)(λ≥1/2)onto the unit circle,where Pn(x)stands for the nth ultraspherical polynomial.展开更多
This paper is an extended research for a novel technique used in the pose error compensations of the robot and manipulator calibration process based on an IT2FEI (interval type-2 fuzzy error interpolation) method. R...This paper is an extended research for a novel technique used in the pose error compensations of the robot and manipulator calibration process based on an IT2FEI (interval type-2 fuzzy error interpolation) method. Robot calibrations can be classified into model-based and modeless methods. A model-based calibration method normally requires that the practitioners understand the kinematics of the robot therefore may pose a challenger for field engineers. An alternative yet effective means for robot calibration is to use a modeless method; however with such a method there is a conflict between the calibration accuracy of the robot and the number of grid points used in the calibration task. In this paper, an interval type-2 fuzzy interpolation system is applied to improve the compensation accuracy of the robot in its 3D workspace. An on-line type-2 fuzzy inference system is implemented to meet the needs of on-line robot trajectory planning and control. The simulated results given in this paper show that not only robot compensation accuracy can be greatly improved, but also the calibration process can be significantly simplified, and it is more suitable for practical applications.展开更多
A family of piecewise rational quintic interpolation is presented. Each interpolation of the family, which is identified uniquely by the value of a parameter ai, is of C^2 continuity without solving a system of consis...A family of piecewise rational quintic interpolation is presented. Each interpolation of the family, which is identified uniquely by the value of a parameter ai, is of C^2 continuity without solving a system of consistency equations for the derivative values at the knots, and can be expressed by the basis functions. Interpolant is of O(h^r) accuracy when f(x)∈C^r[a,b], and the errors have only a small floating for a big change of the parameter ai, it means the interpolation is stable for the parameter. The interpolation can preserve the shape properties of the given data, such as monotonicity and convexity, and a proper choice of parameter ai is given.展开更多
文摘The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was established according to their spectroscopic analysis, such as FT-IR, NMR and mass spectroscopy. These new compounds were tested for their antiproliferative activities on seven representative human tumoral cell lines (Huh7 D12, Caco2, MDA-MB231, MDA-MB468, HCT116, PC3 and MCF7) and also on fibroblasts. Among them, only the compounds 6c showed micromolar cytotoxic activity on tumor cell lines (1.8 50 50 > 25 μM). Finally, in silico ADMET studies ware performed to investigate the possibility of using of the identified compound 6c as potential anti-tumor compound.
文摘An engineering system approach of 2-D cylindrical model of transient mass balance calculations of ozone and other concerned chemicals along with fourteen photolysis, ozone-generating and ozone-depleting chemical reaction equations was developed, validated, and used for studying the ozone concentrations, distribution and peak of the layer, ozone depletion and total ozone abundance in the stratosphere. The calculated ozone concentrations and profile at both the Equator and a 60˚N location were found to follow closely with the measured data. The calculated average ozone concentration was within 1% of the measured average, and the deviation of ozone profiles was within 14%. The monthly evolution of stratospheric ozone concentrations and distribution above the Equator was studied with results discussed in details. The influences of slow air movement in both altitudinal and radial directions on ozone concentrations and profile in the stratosphere were explored and discussed. Parametric studies of the influences of gas diffusivities of ozone D<sub>O3</sub> and active atomic oxygen D<sub>O</sub> on ozone concentrations and distributions were also studied and delineated. Having both influences through physical diffusion and chemical reactions, the diffusivity (and diffusion) of atomic oxygen D<sub>O</sub> was found to be more sensitive and important than that of ozone D<sub>O3</sub> on ozone concentrations and distribution. The 2-D ozone model present in this paper for stratospheric ozone and its layer and depletion is shown to be robust, convenient, efficient, and executable for analyzing the complex ozone phenomena in the stratosphere. .
文摘The authors introduce nonseparable scaling function interpolation and show that its approximation can provide similar convergence properties as scalar wavelet system. Several equivalent statements of accuracy of nonseparable scaling function are also given. In the numerical experiments, it appears that nonseparable scaling function interpolation has better convergence results than scalar wavelet systems in some cases.
基金This research was funded by the Key Research and Development Program of Shandong Province(No.2019GH Z023)the National Natural Science Foundation of China(Nos.41906155,42030406)+1 种基金the Fundamental Research Funds for the Central Universities(No.201762005)the National Key Scientific Instrument and Equipment Development Projects of National Natural Science Foundation of China(No.41527901).
文摘The sea surface height data volume of the future wide-swath two-dimensional(2D)altimetric satellite is thousands of times greater than that of nadir altimetric satellites.The time complexity of the 2D altimetry mapping reaches O(n^(3)).It is challenging to map the global grid products of future 2D altimetric satellites.In this study,to improve the efficiency of global data mapping,a new algorithm called parallel-dynamic interpolation(PA-DI)was designed.Through the use of 2D data segmentation and fine-grained data mosaic methods,the parallel along-track DI processes were accelerated,and a fast and efficient spatial-temporal high-resolution and low-error enhanced mapping method was obtained.As determined from a comparison of the single-threaded DI with the PA-DI,the new algorithm optimized the time complexity from O(n^(3))to O(n^(3)/KL),which improved the mapping efficiency and achieved the expected results.According to the test results of the observing system simulation experiments,the PA-DI algorithm may provide an efficient and reliable method for future wide-swath 2D altimetric satellite mapping.
文摘2-periodic trigonometric interpolation problems on 2n equidistant nodes and 4n+1 equi- distant nodes are considered respectively.Regularity theorems,fundamental polynomials and convergence rate of the corresponding interpolations are given here.
基金supported by Nanyang Technological University,Singapore under the Wallenberg-NTU Presidential Postdoctoral Fellowship and the Natural Science Foundation in Heilongjiang Province,China(YQ2022F003).
文摘This article studies distributed pose(orientation and position)estimation of leader–follower multi-agent systems over𝜅-layer graphs in 2-D plane.Only the leaders have access to their orientations and positions,while the followers can measure the relative bearings or(angular and linear)velocities in their unknown local coordinate frames.For the orientation estimation,the local relative bearings are used to obtain the relative orientations among the agents,based on which a distributed orientation estimation algorithm is proposed for each follower to estimate its orientation.For the position estimation,the local relative bearings are used to obtain the position constraints among the agents,and a distributed position estimation algorithm is proposed for each follower to estimate its position by solving its position constraints.Both the orientation and position estimation errors converge to zero asymptotically.A simulation example is given to verify the theoretical results.
文摘In array signal processing, 2-D spatial-spectrum estimation is required to determine DOA of multiple signals. The circular array of sensors is found to possess several nice properties for DOA estimation of wide-band sources. C. U. Padmini, et al.(1994) had suggested that the frequency-direction ambiguity in azimuth estimation of wide-baud signals received by a uniform linear array (ULA) can be avoided by using a circular array, even without the use of any delay elements. In 2-D spatial-spectrum estimation for wide-band signals, the authors find that it is impossible to avoid the ambiguity in source frequency-elevation angle pairs using a circular array. In this paper, interpolated circular arrays are used to perform 2-D spatial-spectrum estimation for wide-band sources. In the estimation, a large aperture circular array (Υ】λmin/2) is found to possess superior resolution capability and robustness.
文摘In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficients on the input data,a fast and accurate frequency estimator is devised,where only the DFT coefficient with the highest magnitude and its four neighbors are required.Variance analysis is also included to investigate the accuracy of the proposed algorithm.Simulation results are conducted to demonstrate the superiority of the developed scheme,in terms of the estimation performance and computational complexity.
基金Supported by the National Nature Science Foundation.
文摘We study some approximation properties of Lagrange interpolation polynomial based on the zeros of (1-x^2)cosnarccosx. By using a decomposition for f(x) ∈ C^τC^τ+1 we obtain an estimate of ‖f(x) -Ln+2(f, x)‖ which reflects the influence of the position of the x's and ω(f^(r+1),δ)j,j = 0, 1,... , s,on the error of approximation.
文摘This paper presents an engineering system approach using a 2D model of conservation of mass to study the dynamics of ozone and concerned chemical species in the stratosphere.By considering all fourteen photolysis,ozone-generating,and-depleting chemical reactions,the model calculated the transient,spatial changes of ozone under different physical-chemical-radiative conditions.Validation against the measured data demonstrated good accuracy,close match of our model with the observed ozone concentrations at both 20°S and 90°N locations.The deviation in the average concentration was less than 1% and in ozone profiles less than 17%.The impacts of various chlorine-(Cl),nitrogen oxides-(NO_(x)),and bromine-(Br)depleting cycles on ozone concentrations and distribution were investigated.The chlorine catalytic depleting cycle was found to exhibit the most significant impact on ozone dynamics,confirming the key role of chlorine in the problem of ozone depletion.Sensitivity analysis was conducted with levels of 25%,50%,100%,200%,and 400% of the baseline value.The combined cycles(Cl+NO_(x)+Br)showed the most significant influence on ozone behavior.The total ozone abundance above the South Pole could decrease by a small 3%,from 281 DU(Dubson Units)to 273 DU for the 25% level,or by a huge thinning of 60%to 114 DU for the 400% concentration level.When the level of chlorine gases increased beyond 200%,it would cause ozone depletion to a level of ozone hole(below 220 DU).The 2D Ozone Model presented in this paper demonstrates robustness,convenience,efficiency,and executability for analyzing complex ozone phenomena in the stratosphere.
文摘The object in this paper is to consider the problem of existence,uniqueness,explicil representation of(0, 2)-interpolation on the zeros of(1-x^2)P~_(n-1)(x)/x when n is odd,where P_(n-1)denotes Legendre polynomial of degree n-1,and the problem of convergence of interpolatory polynomials.
文摘We discuss the definition and effectiveness of a Padé-type approximation to 2π-periodic finite Baire measures on [-π,π]. In the first two sections we recall the definitions and basic properties of the Padré-type approximants to harmonic functions in the unit disk and to L p -functions on the unit circle. Section 3 deals with the extension of these definitions and properties to a finite 2π-periodic Baire measure. Finally, section 4 is devoted to a study of the convergence of a sequence of such approximants, in the weak star topology of measures.
文摘The object of this paper is to show regularity of(0,1,...,r-2,r) interpolation on the set obtained by projecting vertically the zeros of (1-x2)pn(x)(λ≥1/2)onto the unit circle,where Pn(x)stands for the nth ultraspherical polynomial.
文摘This paper is an extended research for a novel technique used in the pose error compensations of the robot and manipulator calibration process based on an IT2FEI (interval type-2 fuzzy error interpolation) method. Robot calibrations can be classified into model-based and modeless methods. A model-based calibration method normally requires that the practitioners understand the kinematics of the robot therefore may pose a challenger for field engineers. An alternative yet effective means for robot calibration is to use a modeless method; however with such a method there is a conflict between the calibration accuracy of the robot and the number of grid points used in the calibration task. In this paper, an interval type-2 fuzzy interpolation system is applied to improve the compensation accuracy of the robot in its 3D workspace. An on-line type-2 fuzzy inference system is implemented to meet the needs of on-line robot trajectory planning and control. The simulated results given in this paper show that not only robot compensation accuracy can be greatly improved, but also the calibration process can be significantly simplified, and it is more suitable for practical applications.
基金Supported by National Nature Science Foundation of China(No.61070096)the Natural Science Foundation of Shandong Province(No.ZR2012FL05,No.2015ZRE27056)
文摘A family of piecewise rational quintic interpolation is presented. Each interpolation of the family, which is identified uniquely by the value of a parameter ai, is of C^2 continuity without solving a system of consistency equations for the derivative values at the knots, and can be expressed by the basis functions. Interpolant is of O(h^r) accuracy when f(x)∈C^r[a,b], and the errors have only a small floating for a big change of the parameter ai, it means the interpolation is stable for the parameter. The interpolation can preserve the shape properties of the given data, such as monotonicity and convexity, and a proper choice of parameter ai is given.