L2 reading is not only an important channel for people to obtain information and knowledge,but also the main way for people to learn a foreign language.Reading information processing can be divided into controlled pro...L2 reading is not only an important channel for people to obtain information and knowledge,but also the main way for people to learn a foreign language.Reading information processing can be divided into controlled processing and automatic processing.Controlled information processing is a conscious and resource-intensive processing model,while automatic information processing is an unconscious and automatic processing model.This study investigates the characteristics and interactivity of controlled and automatic information processing in L2 reading,and explores the roles of controlled and automatic information processing strategies in improving L2 reading ability.The findings are as follows:(a)controlled and automatic information processing is interactive in L2 reading;and(b)the uses of controlled and automatic information processing strategies are beneficial to the improvement of the reading ability of L2 learners.This study has important theoretical and practical value in improving the efficiency of L2 reading teaching and learning.展开更多
[目的]探讨二肽基肽酶4抑制剂(DPP-4i)对2型糖尿病(T2DM)患者血清肌酐(Cr)的影响。[方法]系统检索PubMed、Embase、Cochrane Library和Web of Science数据库,纳入DPP-4i治疗T2DM患者调节Cr的随机对照试验(RCT)。采用固定效应或随机效应...[目的]探讨二肽基肽酶4抑制剂(DPP-4i)对2型糖尿病(T2DM)患者血清肌酐(Cr)的影响。[方法]系统检索PubMed、Embase、Cochrane Library和Web of Science数据库,纳入DPP-4i治疗T2DM患者调节Cr的随机对照试验(RCT)。采用固定效应或随机效应模型进行数据拟合,采用I^(2)指数定量评价异质性,使用标准方法进行敏感性分析和发表偏倚检验。[结果]经系统检索数据库,纳入12项RCT,共计2276名受试者。由于潜在异质性的原因,故采用随机效应模型进行数据拟合,DPP-4i治疗可轻度提高T2DM患者的Cr水平(WMD:0.15 mg/L,95%CI:0.03~0.27,I^(2)=18%,P=0.02),结果具有统计学差异。根据敏感性测试,Meta分析其结果较为可靠。同时进行Begg’s与Egger’s检验,未见发表偏倚。[结论]T2DM患者应用DPP-4i进行降糖治疗,可能会出现血Cr水平轻度升高。未来还需开展更大样本量的多中心研究,以进一步探讨DPP-4i治疗引起Cr水平改变的临床意义。展开更多
目的探究二甲双胍与门冬胰岛素联合治疗2型糖尿病(Diabetes Mellitus Type 2,T2DM)对血糖的控制效果。方法选取2021年6月—2023年6月吉林省人民医院收治的100例T2DM患者为研究对象,以投掷硬币法分为参照组(n=50,二甲双胍治疗)、观察组(n...目的探究二甲双胍与门冬胰岛素联合治疗2型糖尿病(Diabetes Mellitus Type 2,T2DM)对血糖的控制效果。方法选取2021年6月—2023年6月吉林省人民医院收治的100例T2DM患者为研究对象,以投掷硬币法分为参照组(n=50,二甲双胍治疗)、观察组(n=50,二甲双胍与门冬胰岛素联合治疗)。比较两组临床治疗效果、不良反应总发生率、血糖控制情况及血清炎性因子水平。结果观察组治疗总有效率(96.00%)高于参照组(84.00%),差异有统计学意义(χ^(2)=4.000,P<0.05)。两组不良反应总发生率对比,差异无统计学意义(P>0.05)。与治疗前相比,两组治疗半年后血糖水平、白细胞介素-6、白细胞介素-12水平均降低、白细胞介素-10水平升高,且观察组上述指标优于参照组,差异有统计学意义(P均<0.05)。结论二甲双胍与门冬胰岛素联合治疗T2DM患者时可提高疗效,患者血糖控制情况更佳,血清炎性因子水平也得到明显改善,安全性较高。展开更多
Superconducting YBa_(2)Cu_(3)O_(7−x)(YBCO)bulks have promising applications in quasi-permanent magnets,levitation,etc.Recently,a new way of fabricating porous YBCO bulks,named direct-ink-writing(DIW)3D-printing method...Superconducting YBa_(2)Cu_(3)O_(7−x)(YBCO)bulks have promising applications in quasi-permanent magnets,levitation,etc.Recently,a new way of fabricating porous YBCO bulks,named direct-ink-writing(DIW)3D-printing method,has been reported.In this method,the customized precursor paste and programmable shape are two main advantages.Here,we have put forward a new way to customize the YBCO 3D-printing precursor paste which is doped with Al_(2)O_(3)nanoparticles to obtain YBCO with higher thermal conductivity.The great rheological properties of precursor paste after being doped with Al_(2)O_(3)nanoparticles can help the macroscopic YBCO samples with high thermal conductivity fabricated stably with high crystalline and lightweight properties.Test results show that the peak thermal conductivity of Al_(2)O_(3)-doped YBCO can reach twice as much as pure YBCO,which makes a great effort to reduce the quench propagation speed.Based on the microstructure analysis,one can find that the thermal conductivity of Al_(2)O_(3)-doped YBCO has been determined by its components and microstructures.In addition,a macroscopic theoretical model has been proposed to assess the thermal conductivity of different microstructures,whose calculated results take good agreement with the experimental results.Meanwhile,a microstructure with high thermal conductivity has been found.Finally,a macroscopic YBCO bulk with the presented high thermal conductivity microstructure has been fabricated by the Al_(2)O_(3)-doped method.Compared with YBCO fabricated by the traditional 3D-printed,the Al_(2)O_(3)-doped structural YBCO bulks present excellent heat transfer performances.Our customized design of 3D-printing precursor pastes and novel concept of structural design for enhancing the thermal conductivity of YBCO superconducting material can be widely used in other DIW 3D-printing materials.展开更多
文摘L2 reading is not only an important channel for people to obtain information and knowledge,but also the main way for people to learn a foreign language.Reading information processing can be divided into controlled processing and automatic processing.Controlled information processing is a conscious and resource-intensive processing model,while automatic information processing is an unconscious and automatic processing model.This study investigates the characteristics and interactivity of controlled and automatic information processing in L2 reading,and explores the roles of controlled and automatic information processing strategies in improving L2 reading ability.The findings are as follows:(a)controlled and automatic information processing is interactive in L2 reading;and(b)the uses of controlled and automatic information processing strategies are beneficial to the improvement of the reading ability of L2 learners.This study has important theoretical and practical value in improving the efficiency of L2 reading teaching and learning.
文摘[目的]探讨二肽基肽酶4抑制剂(DPP-4i)对2型糖尿病(T2DM)患者血清肌酐(Cr)的影响。[方法]系统检索PubMed、Embase、Cochrane Library和Web of Science数据库,纳入DPP-4i治疗T2DM患者调节Cr的随机对照试验(RCT)。采用固定效应或随机效应模型进行数据拟合,采用I^(2)指数定量评价异质性,使用标准方法进行敏感性分析和发表偏倚检验。[结果]经系统检索数据库,纳入12项RCT,共计2276名受试者。由于潜在异质性的原因,故采用随机效应模型进行数据拟合,DPP-4i治疗可轻度提高T2DM患者的Cr水平(WMD:0.15 mg/L,95%CI:0.03~0.27,I^(2)=18%,P=0.02),结果具有统计学差异。根据敏感性测试,Meta分析其结果较为可靠。同时进行Begg’s与Egger’s检验,未见发表偏倚。[结论]T2DM患者应用DPP-4i进行降糖治疗,可能会出现血Cr水平轻度升高。未来还需开展更大样本量的多中心研究,以进一步探讨DPP-4i治疗引起Cr水平改变的临床意义。
文摘目的探究二甲双胍与门冬胰岛素联合治疗2型糖尿病(Diabetes Mellitus Type 2,T2DM)对血糖的控制效果。方法选取2021年6月—2023年6月吉林省人民医院收治的100例T2DM患者为研究对象,以投掷硬币法分为参照组(n=50,二甲双胍治疗)、观察组(n=50,二甲双胍与门冬胰岛素联合治疗)。比较两组临床治疗效果、不良反应总发生率、血糖控制情况及血清炎性因子水平。结果观察组治疗总有效率(96.00%)高于参照组(84.00%),差异有统计学意义(χ^(2)=4.000,P<0.05)。两组不良反应总发生率对比,差异无统计学意义(P>0.05)。与治疗前相比,两组治疗半年后血糖水平、白细胞介素-6、白细胞介素-12水平均降低、白细胞介素-10水平升高,且观察组上述指标优于参照组,差异有统计学意义(P均<0.05)。结论二甲双胍与门冬胰岛素联合治疗T2DM患者时可提高疗效,患者血糖控制情况更佳,血清炎性因子水平也得到明显改善,安全性较高。
基金supported by the Fund of Natural Science Foundation of China(No.11872196,12232005)supported by the Outstanding Postgraduate‘Innovation Star’Fund for Distinguished of Gansu Province(No.2021CXZX-032).
文摘Superconducting YBa_(2)Cu_(3)O_(7−x)(YBCO)bulks have promising applications in quasi-permanent magnets,levitation,etc.Recently,a new way of fabricating porous YBCO bulks,named direct-ink-writing(DIW)3D-printing method,has been reported.In this method,the customized precursor paste and programmable shape are two main advantages.Here,we have put forward a new way to customize the YBCO 3D-printing precursor paste which is doped with Al_(2)O_(3)nanoparticles to obtain YBCO with higher thermal conductivity.The great rheological properties of precursor paste after being doped with Al_(2)O_(3)nanoparticles can help the macroscopic YBCO samples with high thermal conductivity fabricated stably with high crystalline and lightweight properties.Test results show that the peak thermal conductivity of Al_(2)O_(3)-doped YBCO can reach twice as much as pure YBCO,which makes a great effort to reduce the quench propagation speed.Based on the microstructure analysis,one can find that the thermal conductivity of Al_(2)O_(3)-doped YBCO has been determined by its components and microstructures.In addition,a macroscopic theoretical model has been proposed to assess the thermal conductivity of different microstructures,whose calculated results take good agreement with the experimental results.Meanwhile,a microstructure with high thermal conductivity has been found.Finally,a macroscopic YBCO bulk with the presented high thermal conductivity microstructure has been fabricated by the Al_(2)O_(3)-doped method.Compared with YBCO fabricated by the traditional 3D-printed,the Al_(2)O_(3)-doped structural YBCO bulks present excellent heat transfer performances.Our customized design of 3D-printing precursor pastes and novel concept of structural design for enhancing the thermal conductivity of YBCO superconducting material can be widely used in other DIW 3D-printing materials.