A New Synthetic Route for Preparation of 2-Chloro-6-fluoro- benzonitrile and 2-Chloro-6-fluorobenzoic Acid

An effective synthetic route for preparation of 2-chloro-6-fluorobenzonitrile, 2-chloro-6-fluorobenzamide and 2-chloro-6-fluorobenzoic acid has been described. It includes diazotization, fluorination, ammoxidation and hydrolysis reactions.

Crystal Structure and Biological Activities of (R)-N′-[2-(4-Methoxy-6-chloro)-pyrimidinyl]-N-[3-methyl-2-(4-chlorophenyl)butyryl]-urea

The title compound （R）-N′-[2-（4-methoxy-6-chloro）-pyrimidyl]-N-[3-methyl-2-（4- chlorophenyl）butyryl]-urea has been synthesized, and its crystal structure and biological behaviors were studied. Crystallographic data： C17H18C12N4O3, Mr = 397.25, monoclinic, space group P21/c, a = 12.331（2）, b = 14.025（3）, c = 23.085（5） A, β = 99.607（4）°, Z = 8, V = 3936.2（13） A3, Dc = 1.341 g/cm^3, F（000） = 1648, R = 0.0718, wR = 0.1585 and/t（MoKα） = 0.353 mm^-1. The preliminary biological tests showed that the title compound has definite insecticidal and fungicidal activities.

树脂吸附法处理高浓度含氟芳香烃废水及其资源化

2-氯-6-氟氯苄和2-氯-6-氟苯甲醛等为关键医药中间体，在其生产过程中产生了大量高浓度含氟芳香烃废水，造成环境污染。本研究采用大孔吸附树脂对该废水进行了治理。结果表明，在温度为303K、pH为3-6、流速为5BV／h的条件下，LS600和LS106树脂对COD的去除率达73．4％，对3-氯-2-甲基苯酚、2-氯-6-氟苯甲醛和2-氯-6-氟苯甲酸的去除率达98．1％以上，可去除氟离子100～120mg／L，同时废水中有用资源可得到有效再生利用。