A sutureless technique for securing leaking sclerotomies with viscoelastic substances in 23-gauge microincision vitrectomy surgery

AIM:To introduce and evaluate the clinical efficacy of a new technique,the use of viscoelastic substances(VS)to close leaking sclerotomy in 23G microincision vitrectomy,and to observe its effect on the visual acuity and intraocular pressure(IOP)of patients.METHODS:Patients who underwent 23G vitrectomy in Ningbo Eye Hospital before the use of VS technique(June 2019 to September 2020)and after the use of VS technique(October 2020 to December 2021)were selected as the subjects of this study.The above cases underwent operation by the same surgeon and were retrospectively analyzed.VS technique was used as the alternative to suturing,in which a small amount of VS was injected at the leaking sclerotomy and then gently massaged to confirm leaking sclerotomy closure.RESULTS:A total of 174 eyes were covered in the study,including 84 eyes in the control group(before the use of VS technique)and 90 eyes in the VS technique group.The number of eyes that needed to be sutured decreased considerably from 42.9%in the control group to 3.3%in the VS technique group,and the proportion of subconjunctival hemorrhage at 1-2d after surgery decreased remarkably from 35.7%in the control group to 2.2%in the VS technique group.No substantial differences in the incidence of mean IOP and low IOP were found between 1-2 and 3-20d after surgery in the VS technique group.No major complications associated with VS technique were identified during the study.CONCLUSION:In 23G microincision vitrectomy,VS technique is a safe,simple,and effective method to close leaking sclerotomy.

25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma: a case series and review of the literature

AIM:To report the cytology results of 25-gauge transconjunctival(25G-TSV)diagnostic vitrectomy in cases suspicious for intraocular lymphoma(IOL),and compare the results to those reported in the literature.METHODS:Clinical and cytopathological records of 18vitreous biopsy specimens obtained via 25G-TSV diagnostic vitrectomy in 12 patients suspicious for IOL were reviewed retrospectively.A review of the literature in regards to the diagnostic yields of vitreous specimens obtained via 25-gauge and 20-gauge diagnostic vitrectomy in suspected cases of IOL was performed.RESULTS:Eighteen eyes from 12 patients with clinical suspicion of IOL underwent diagnostic 25G-TSV.The cytopathological investigations demonstrated IOL in 15eyes(83.3%).Vitreous analysis was non-diagnostic in 3eyes(16.7%).CONCLUSION:Twenty-five-gauge diagnostic vitrectomy yields adequate sample for cytological evaluation of the vitreous in cases suspicious for IOL.The diagnostic results of the 25G-TSV in the current study are superior to those reported for 20-gauge vitrectomy but equivalent to those reported for 25G-TSV in the published literature.

Corneal topographic changes and surgically induced astigmatism following combined phacoemulsification and 25-gauge vitrectomy

AIM： To evaluate corneal topographic changes and surgically induced astigmatism （SIA） after combined phacoemulsification and 25-gauge transconjunctival sutureless vitrectomy （25-G TSV）.METHODS： A retrospective study on 96 eyes of 87 patients who underwent combined phacoemulsification and 25-G TSV. The different topographic parameters and SIA were analyzed pre- and postoperatively.RESULTS： There was no significant changes in corneal topographic parameters at different follow up periods. Only surface regularity index changed significantly in the 2nd postoperative week and then returned to baseline values thereafter. Mean SIA gradually decreased to reach 0.12 D by the 6th postoperative month.CONCLUSION： Corneal surface and astigmatic changes are insignificant in either early or late postoperative periods following combined phacoemulsification and 25-G TSV. The SIA was the minimum among previous reports on sutureless vitrectomy alone or combined with phacoemulsification. Improvement of SIA did not stop at the 3rd postoperative month but it continued till the 6th month postoperatively.

新型25-Gauge与传统20-Gauge玻璃体切除术后干眼对比

目的:对比25-Gauge与20-Gauge玻璃体切除术后患者干眼症状的严重程度。方法:在玻璃体切除手术的患者中,20-Gauge手术26例26眼,25-Gauge手术21例21眼,于手术前及术后3,7及30d,做干眼症状评分、泪液分泌试验、泪膜破裂时间及角膜荧光素钠染色评分比较。结果:与25G手术后患者相比,术后3,7d,20G手术患者干眼症状明显(P<0.05)、泪液分泌量增多(P<0.05)、泪膜破裂时间缩短(P<0.05)、角膜荧光素钠着色明显(P<0.05),上述差异具有统计学意义;术后30d,两组泪液分泌量无统计学差异,其他指标仍具有统计学差异(P<0.05)。结论:25G手术与20G手术相比,对眼表创伤较小,患者术后干眼的情况相对较轻。

Outcomes of transconjunctival sutureless 27-gauge vitrectomy for vitreoretinal diseases

AIM： To evaluate the safety and efficacy profile of 27-gauge （27G） pars plana vRrectomy （PPV） for the treatment of various vitreoretinal diseases. METHODS： The clinical outcomes of 61 eyes （58 patients） with various vitreoretinal diseases following 27G PPV were retrospectively reviewed. RESULTS： Surgical indications included rhegmatogenous retinal detachment （n=24）, full-thickness macular hole （n=12）, diabetic retinopathy （n=11）, vitreous hemorrhage （n=6）, Eales disease （n=4）, pathological myopia-related vitreous floater （n=2）, and macular epiretinal membrane （n=2）. The mean follow-up was 166.4±61.3d （range 98-339d）. The mean IogMAR best-corrected visual acuity （BCVA） improved from 1.7±1.1 [0.02 decimal visual acuity （VA） equivalent] preoperatively to 1.2±1.0 （0.06 decimal VA equivalent） at the last postoperative visit （P〈0.001）. The mean operative time was 49.gmin. With the exception of complicated cataract in one eye, no intraoperative complications were encountered. No case required conversion to conventional 20-, 23- or 25G instrumentation in all surgical maneuvers except for silicone oil infusion, which required a 25G oil injection syringe. Postoperative complications included transient ocular hypertension, vitreous hemorrhage, persistent intraocular pressure elevation, subconjunctival oil leakage, and recurrent retinal detachment. No cases of hypotony, endophthalmitis, and sclerotomy-related tears were observed. CONCLUSION： The current results suggest that 27G PPV system is a safe and effective treatment for various vitreoretinal diseases. When learning to perform 27G PPV,surgeons may encounter a learning curve and should gradually expand surgical indications from easy to pathologically complicated cases.

Ahmed valve implantation for neovascular glaucoma after 23-gauge vitrectomy in eyes with proliferative diabetic retinopathy

·AIM: To report on the outcome of Ahmed glaucoma valve (AGV) implantation for the management of neovascular glaucoma (NVG) after 23 -gauge vitrectomy for proliferative diabetic retinopathy (PDR). ·METHODS: Twelve medically uncontrolled NVG with earlier 23 -gauge vitrectomy for PDR underwent AGV implantation. The control of intraocular pressure (IOP), preoperative and postoperative best -corrected visual acuity, the development of intraoperative and postoperative complications were evaluated during the follow-up. ·RESULTS: The mean follow-up was 15.4±4.3 months (9-23 months). Mean preoperative IOP was 49.4±5.1mmHg and mean postoperative IOP at the last visit was 17.5 ± 1.6mmHg. The control of IOP was achieved at the final follow -up visits in all patients, however, 8 of 12 patients still needed anti-glaucoma medication (mean number of medications, 0.8±0.7). The visual acuity improved in nine eyes, and the visual acuity unchanged in three eyes at the final follow -up visits. The complications that occurred were minor hyphema in three eyes, choroid detachment in two eyes, and the minor hyphema and choroid detachments were reabsorbed without any surgical intervention. ·CONCLUSION: AGV implantation is a safe and effective procedure that enables successful IOP control and vision preservation in the NVG patients with the history of earlier 23-gauge vitrectomy for PDR.·

Outcomes of transconjuctival sutureless 27-gauge vitrectomy for stage 4 retinopathy of prematurity

AIM To report our initial experience with lens-sparing vitrectomy for stage 4 retinopathy of prematurity using the 27-gauge(G) system.METHODS This retrospective case series involved nine eyes of five babies with active stage 4 ROP, who underwent 27-G lens-sparing vitrectomy. Surgery was done using 27-G valved cannulas and sclerotomies were made 1.5 mm from the limbus. Bilateral sequential vitrectomy was done in eight eyes. RESULTS At one-year follow-up, anatomical outcome was favourable in all nine(100%) eyes. High-speed cutting and smaller sclerotomies were helpful in reducing the intra and post-operative complications. CONCLUSION27-G vitrectomy is well suited for stage 4 ROP surgeries.

23-Gauge Pars Plana Vitrectomy Alone by a Bimanual Technique for the Removal of Dense Posteriorly Dislocated Crystalline Lens

Background: We sought to verify the efficacy and safety of transconjunctival 23-gauge pars plana vitrectomy (PPV) alone by our bimanual technique for the removal of dense posteriorly dislocated crystalline lens. Methods: A retrospective, noncomparative, interventional study of 31 consecutive cases of patients who underwent 23-gauge PPV alone for the removal of dense posteriorly dislocated crystalline lens following complicated cataract surgeries using our bimanual technique was conducted. The main outcomes measured included best-corrected visual acuity (BCVA), preoperative intraocular pressure (IOP), postoperative IOP and postoperative complications. Results: In all 31 cases included in this study, those dense posteriorly dislocated crystalline lenses were successfully removed. The enrolled patients consisted of 17 males and 14 females with a mean age of (75.84 ± 6.17) years (range 59 - 90). The mean follow-up length was (7.61 ± 1.87) months with a range of 6 months to 1 year. The mean preoperative BCVA was 0.22 ± 0.11 logMAR system, and the postoperative BCVA was 0.33 ± 0.07 logMAR system after 6 months of follow-up. The mean operative time was 46.32 ± 4.80 minutes with a range of 38.00 to 57.00 minutes. All of the conjunctival incisions self-closed within the first week with no wound leakage or hemorrhage. The postoperative complications were relatively rare. Conclusions: The removal of dense posteriorly dislocated crystalline lens might be a challenge for micro-incision vitrectomy. Our bimanual technique was proved to be an effective and safe method for those particular dense lenses using 23-gauge alone.

Differential distribution of fibrovascular proliferative membranes in 25-gauge vitrectomy for proliferative diabetic retinopathy

AIM:To analyze the distribution of fibrovascular proliferative membranes(FVPMs)in proliferative diabetic retinopathy(PDR)patients that treated with pars plana vitrectomy(PPV),and to evaluate the outcomes separately.METHODS:This was a retrospective and cross-sectional study.Consecutive 25-gauge(25-G)PPV cases operated for PDR from May 2018 to April 2020.According to the FVPMs images outlined after operations,subjects were assigned into three groups:arcade type group,juxtapapillary type group,and central type group.All patients were followed up for over one year.General characteristics,operation-related variables,postoperative parameters and complications were recorded.RESULTS:Among 103 eyes recruited,the FVPMs distribution of nasotemporal and inferiosuperioral was significantly different(both P<0.01),with 95(92.23%)FVPMs located in the nasal quadrants,and 74(71.84%)in the inferior.The eyes with a central FVPM required the longest operation time,with silicon oil used in most patients,generally combined with tractional retinal detachment(RD)and rhegmatogenous RD,the worst postoperative bestcorrected visual acuity(BCVA)and the highest rates of recurrent RD(all P<0.05).FVPM type,age of onset diabetes mellitus,preoperative BCVA,and combined with tractional RD and rhegmatogenous RD were significantly associated with BCVA improvement(all P<0.05).Compared with the central type group,the arcade type group had higher rates of BCVA improvement.CONCLUSION:FVPMs are more commonly found in the nasal and inferior mid-peripheral retina in addition to the area of arcade vessels.Performing 25-G PPV for treating PDR eyes with central FVPM have relatively worse prognosis.

Primary 23-gauge vitreoretinal surgery for rhegmatogenous retinal detachment

AIM: To report the effectiveness and safety of primary 23-Gauge (G) vitreoretinal surgery for rhegmatogenous retinal detachment (RRD). · METHODS: In this retrospective study, 49 eyes of 49 consecutive patients who underwent primary 23-G transconjunctival sutureless vitrectomy (TSV) for RRD between January 2007 and July 2009 at our institution were evaluated. · RESULTS: Mean follow-up time was 8.9±7.7 months (1-28 months). Retinal reattachment was achieved with a single operation in 47(95.9%) of 49 eyes. In two eyes (4.1%), retinal redetachment due to new breaks was successfully treated with reoperation using the 23-G TSV system. Mean logMAR visual acuity was 2.01±0.47 preoperatively and 1.3±0.5 postoperatively (P <0.001, Paired t -test). Mean preoperative intraocular pressure (IOP) was 14.1±2.8mmHg. Mean postoperative IOP was 12.3±3.6mmHg at 1 day, 13.1±2.1mmHg at 1 week, 14.3±2.2mmHg at 1 month. Iatrogenic peripheral retinal break was observed in 1 eye(2.0%) intraoperatively. No sutures were required to close the scleral or conjunctival openings, and no eyes required convertion of surgery to 20-G vitrectomy. · CONCLUSION: Primary 23-G TSV system was observed to be effective and safe in the treatment of RRD.

27G+/25G+微创玻璃体切割手术治疗玻璃体视网膜疾病的比较

目的:对比分析25G+与27G+微创玻璃体切割手术治疗玻璃体视网膜疾病的疗效及安全性。方法:回顾性分析2019-03/2022-04于我院行玻璃体切割手术的玻璃体视网膜病变患者89例89眼的临床资料,根据手术方式分为A组(45例45眼,行25G+微创玻璃体切割手术)和B组(44例44眼,行27G+微创玻璃体切割手术),分析两组患者术中玻璃体切割时间和手术完成时间、手术前后最佳矫正视力(BCVA)和眼压情况及术后主观舒适度和并发症情况。结果:两组术中玻璃体切割时间无差异(P>0.05),但B组手术完成时间短于A组(35.50±14.27min vs 41.73±14.25min,P=0.042)。两组术后BCVA均优于术前(P<0.05),但两组间无显著差异(P>0.05)。两组术后眼压均低于术前(P<0.05),且术后1、7d A组眼压略低于B组(P<0.05)。术后1d, A组主观舒适度评分高于B组(6.13±1.20分vs 3.45±1.17分,P<0.001);术后7d,两组主观舒适度评分无差异(2.18±1.01分vs 1.93±0.87分,P=0.215)。随访期间,A组发生切口渗漏7眼(16%),其中一过性低眼压6眼(13%),术后出现结膜水肿10眼(22%);B组未见切口渗漏及一过性低眼压,术后1d发生结膜水肿2眼(4%)。结论:25G+与27G+微创玻璃体切割手术均可改善玻璃体视网膜病变患者的视力,稳定眼压,且安全,但27G+微创玻璃体切割手术后切口渗漏发生较少,眼压较稳定,手术时间相对缩短,且结膜水肿发生率更低。

经结膜无缝合25G玻璃体切割术灌注系统的临床应用探讨

目的:经结膜无缝合玻璃体切割手术灌注系统应用于常规玻璃体切割术,探讨其临床应用价值及手术适应证,并发症。方法:玻璃体切割术患者196眼(190例),其中孔源性视网膜脱离142眼,单纯玻璃体积血患者20眼,糖尿病视网膜病变伴玻璃体积血26眼,特发性黄斑裂孔或黄斑前膜8眼,随机分层分为2组,每组98眼。一组采用经结膜无缝合玻璃体切割手术灌注系统,另一组采用常规玻璃体切割灌注系统。完成三通道经睫状体平坦部玻璃体切割术。包括黄斑部手术操作,使用20G玻切刀、视网膜钩、镊、笛形针、电凝等进行视网膜周边部操作,内界膜及视网膜前增殖膜剥除,视网膜切开,气液交换,视网膜光凝、冷凝等复杂视网膜手术操作。手术结束时仅缝合玻切刀及光纤头巩膜创口,经结膜无缝合玻璃体切割手术灌注系统穿刺口无需缝合。术后随访2～7mo。结果:随访期间所有患者均未发现感染性眼内炎及切口持续性渗漏等并发症。采用经结膜无缝合玻璃体切割手术灌注系统患者全部手术时间平均78min,采用常规玻切灌注系统,其平均手术时间为95min,两组差别有统计学意义(P<0.05)手术后并发症包括视网膜再脱离,一过性眼压升高,玻璃体积血等比较无显著性差异。结论:经结膜无缝合玻璃体切除手术灌注系统应用于常规玻璃体切割术,治疗黄斑疾病,玻璃体积血及视网膜脱离等多种较复杂的疾病,扩大了经结膜无缝合玻璃体切除手术灌注系统的临床应用范围,未观察到与改换灌注系统相关的手术并发症。有效缩短手术时间及减少手术创伤。

25G经结膜穿刺法玻璃体切割术治疗特发性黄斑裂孔

目的:探讨小切口玻璃体切割术治疗特发性黄斑裂孔的手术效果。方法:7例(7眼)经眼底及OCT检查确诊为特发性黄斑裂孔,施行25G经结膜穿刺法玻璃体切割术,剥离视网膜前膜,眼内惰性气体填充,观察术后视力及裂孔封闭情况。结果:7例(7眼)黄斑裂孔均解剖复位,2眼视力无改善,5眼视力提高1～4行,随访1～6mo无裂孔复发者。结论:玻璃体切割术是治疗特发性黄斑裂孔的有效方法,经结膜小切口法较传统玻璃体切割术有明显的优势。

23GTVS与25GTVS治疗复杂性孔源性视网膜脱离的临床疗效观察

目的比较23G、25G经结膜无缝合玻璃体切割手术系统(transconjuctival-sutureless vitrectomy system,TVS)治疗复杂性孔源性视网膜脱离的安全性和有效性。方法回顾性分析2008年1月至2011年6月因复杂性孔源性视网膜脱离在我院行23G TVS患者60例(60眼)及25G TVS患者42例(42眼)的临床资料。对比观察手术效果及手术时间、术后眼压及并发症等。结果 102例患者中,仅2例改行传统玻璃体切割术,其余病例均顺利完成手术。23G TVS组手术时间为35～70min,平均55min;25G TVS组手术时间为40～65min,平均51min;差异无统计学意义(P=0.372)。术后第1天23G TVS组眼压为(9.0±6.1)mmHg(1kPa=7.5mmHg),25G TVS组眼压为(10.0±5.6)mmHg,差异无统计学意义(P=0.420)。23G TVS、25G TVS手术有效率分别为88.3%、83.3%,差异无统计学意义(P>0.05)。23G TVS组术后发生视网膜脱离4例,脉络膜脱离1例,玻璃体积血2例,切口渗漏4例;25G TVS组视网膜脱离2例,玻璃体积血3例,切口渗漏7例;两组术后视网膜脱离、玻璃体积血发生率差异均无统计学意义(P=0.689、0.383),切口渗漏发生率差异有统计学意义(P=0.023)。结论在治疗复杂性孔源性视网膜脱离方面,23G TVS较25G TVS能有效防治切口渗漏的发生,其他并发症发生率无差异。[眼科新进展,2013,33(1):77-79]

23G与25G+微创玻璃体切除术治疗玻璃体积血的临床对比观察

目的对比观察23G、25G＋经结膜免缝合玻璃体切除术（TVS）治疗玻璃体积血的安全性和有效性。方法对比分析2013年3月至2014年3月因玻璃体积血在我院行两种不同微创玻璃体切除术（23G和25G＋）患者的临床资料,采用t检验或秩和检验以及χ~2检验对比观察手术时间、切口闭合情况、术后眼压、术后视力及并发症等。结果共计45例（47只眼）,其中21例（22只眼）行23G微创玻璃体切除患者术（23G组）,24例（25只眼）行25G＋微创玻璃体切除术（25G＋组）;23G组手术时间为35~94 min,平均55.4 min;25G＋组手术时间为30~85 min,平均47.6 min;差异无统计学意义（P=0.105）。23G组、25G＋组手术切口自然闭合比率分别为45.5%、80.0%,缝合率分别54.5%、20.0%,差异有统计学意义（P=0.018）。术后第1天23G组眼压为（9.1±3.8）mmHg,25G＋组眼压为（10.2±2.6）mm Hg,差异无统计学意义（P=0.712）,术后第3天23G组眼压为（10.3±4.1）mm Hg,25G＋组眼压为（10.9±3.7）mm Hg,差异无统计学意义（P=1.000）,术后1周23G组眼压为（14.3±6.9）mm Hg,25G＋组眼压为（15.7±6.3）mm Hg,差异无统计学意义（P=0.371）;23G组术后视力改善情况与25G＋组无统计学差异（P=0.807）;23G组术后发生视网膜脱离1例,切口渗漏1例,复发玻璃体积血3例;25G＋组术后发生视网膜脱离2例,切口渗漏2例,复发玻璃体积血1例;两组发生率差异均无统计学意义（P=1.000、1.000、0.328）。结论 25G＋TVS与23G TVS均是有效的玻璃体积血治疗方法,25G＋TVS切口自然闭合率更好,其他并发症发生率无差异。

25G玻璃体手术治疗儿童后发性白内障

目的探讨25G玻璃体手术治疗儿童后发性白内障的疗效。方法对7例(10只眼)儿童后发性白内障患者以透明角膜切口插管灌注,TSV25G玻璃体手术行后囊膜切除联合前段玻璃体切除术。术后平均随访23个月,观察视力、眼压、前房反应和并发症的发生情况。结果所有术眼晶状体后囊膜中央均形成直径约4mm的圆形透明区,术中前房稳定,人工晶状体无损伤。全部患儿术后最佳矫正视力均较术前提高。随访期间无切口渗漏、角膜水肿、眼内炎、瞳孔区玻璃体疝、人工晶状体损伤、视网膜脱离、高眼压及晶状体后囊膜切开区再次混浊等并发症。结论 25G玻璃体手术治疗儿童后发性白内障安全、有效、便捷。

25G玻璃体手术系统在厚的后发性白内障手术中的应用

目的探讨应用25G玻璃体手术系统治疗厚的后发性白内障的疗效。方法应用25G经结膜无缝合玻璃体切割术对16例(16眼)厚的后发性白内障患者行后囊膜切开+前段玻璃体切割术。术后随访2～6个月,记录视力、眼压,观察晶状体后囊膜切开区情况及并发症情况。结果所有手术均顺利完成。术后视力均明显提高,术后1周和末次随访时最佳矫正视力≥0.5的术眼分别占75.0%(12/16)、81.3%(13/16)。除1眼术后发生暂时性低眼压(术后3d恢复正常)外,其余患眼随访期内眼压均在正常范围。全部术眼晶状体后囊膜中央均形成直径为3.0～4.0mm的圆形透明区,视轴区透明,术中、术后均未见明显并发症发生。结论 25G经结膜无缝合玻璃体切割系统通过切开晶状体后囊膜和切除前段玻璃体治疗厚的后发性白内障安全、有效。

经透明角膜切口25G玻璃体切割系统在婴幼儿先天性白内障中的应用

目的:评价经透明角膜缘切口25G玻璃体切割手术系统(TSV25G)在婴幼儿先天性白内障手术中应用的临床疗效。方法:回顾分析17例(28只眼)婴幼儿先天性白内障患者的临床资料。其中5例(8只眼)为早产儿,在行早产儿视网膜疾病筛查时发现先天性白内障。12例(20只眼)为足月产婴幼儿,因家长发现其白瞳症而就诊。所有患儿在全身麻醉下通过25G玻切头经透明角膜切口行晶状体切除、后囊膜环形切开以及前部玻璃体切割手术。手术后随访3个月至1年,观察术后视力、眼压、前房反应、虹膜后粘连、后囊膜混浊等术后并发症情况。结果:17例(28只眼)术后视力较术前均有提高。术后前房反应轻,无虹膜后粘连、后囊膜混浊、低眼压、眼内炎、黄斑囊样水肿和视网膜脱离等并发症发生。结论:对于婴幼儿先天性白内障,通过25G玻切头经透明角膜切口行晶状体切除、后囊膜环形切开以及前部玻璃体切割手术,具有操作容易控制、手术创伤小、术后炎性反应轻等优点,能有效抑制后发性白内障的发生,有助于视功能的恢复。

25G玻璃体腔灌注在玻璃体切除术后的白内障超声乳化手术中的应用

目的：探讨25G玻璃体腔灌注在玻璃体切除术后的白内障超声乳化手术中的应用效果。方法：选取2013-09/2014-09于我院诊治的经睫状体平坦部玻璃体切除术后白内障患者48例50眼,对其行预置25G玻璃体腔灌注下白内障超声乳化联合人工晶状体植入术,观察术后最佳矫正视力、眼压、术后不适、巩膜穿刺口愈合情况及术后并发症。结果：所有患者均顺利完成手术。与手术前相比,患者白内障手术后90d最佳矫正视力≤0.1的眼数较少,最佳矫正视力0.3~0.5、〉0.5、〉0.3的眼数较多,差异有统计学意义（P〈0.05）。1眼因为原有眼底病变复发引起玻璃体积血,视力较术前下降。术前、术后1、7d,6mo平均眼压分别为14.67±0.62、14.75±0.56、14.86±0.58、14.88±0.59mmH g。眼压在患者白内障手术前与术后1、7d,6mo间比较差异无统计学意义（P〉0.05）。术后无明显眼部不适及严重并发症。结论：25G玻璃体腔灌注应用于玻璃体切除术后的白内障超声乳化手术中对维持眼压、稳定前房及减少并发症有益处。

27G玻璃体切割术治疗糖尿病视网膜病变的疗效分析

目的比较使用23G、25G、27G玻璃体切割术治疗糖尿病视网膜病变(DR)患者的临床疗效。方法将我院于2020年1月~2021年1月期间行手术治疗的60例DR患者分为三组,每组20例。A组实施27 G玻璃体切割术,B组实施25 G玻璃体切割术,C组实施23 G玻璃体切割术,对三组眼压、视网膜厚度变化、临床活动度评分(CAS)及DR病变早期治疗研究(ETDRS)评分进行比较。结果治疗前,三组眼压水平比较,差异无统计学意义(P>0.05),治疗后三组眼压水平明显降低(P<0.05),A组眼压与B、C组相比波动更小(P<0.05)。治疗前,三组的视网膜厚度比较,差异无统计学意义(P>0.05);治疗后1、3个月,A组的视网膜厚度显著低于B、C组(P<0.05)。治疗前,三组CAS评分比较,差异无统计学意义(P>0.05);治疗后A组CAS评分显著低于B、C组,差异有统计学意义(P<0.05)。治疗前,三组ETDRS评分对比,差异无统计学意义(P>0.05),治疗后三组ETDRS评分明显下降(P<0.05),但治疗后三组ETDRS评分对比,差异无统计学意义(P>0.05)。结论27G玻璃体切割术应用于DR患者治疗中效果较好,能够降低眼压波动,改善视力水平与眼部功能。