Photocatalytic CO_(2)reduction to produce high value-added carbon-based fuel has been proposed as a promising approach to mitigate global warming issues.However,the conversion efficiency and product selectivity are st...Photocatalytic CO_(2)reduction to produce high value-added carbon-based fuel has been proposed as a promising approach to mitigate global warming issues.However,the conversion efficiency and product selectivity are still low due to the sluggish dynamics of transfer processes involved in proton-assisted multi-electron reactions.Lowering the formation energy barriers of intermediate products is an effective method to enhance the selectivity and productivity of final products.In this study,we aim to regulate the surface electronic structure of Bi_(2)WO_(6)by doping surface chlorine atoms to achieve effective photocatalytic CO_(2)reduction.Surface Cl atoms can enhance the absorption ability of light,affect its energy band structure and promote charge separation.Combined with DFT calculations,it is revealed that surface Cl atoms can not only change the surface charge distribution which affects the competitive adsorption of H_(2)O and CO_(2),but also lower the formation energy barrier of intermediate products to generate more intermediate*COOH,thus facilitating CO production.Overall,this study demonstrates a promising surface halogenation strategy to enhance the photocatalytic CO_(2)reduction activity of a layered structure Bi-based catalyst.展开更多
P2/O3-type Ni/Mn-based layered oxides are promising cathode materials for sodium-ion batteries(SIBs)owing to their high energy density.However,exploring effective ways to enhance the synergy between the P2 and 03 phas...P2/O3-type Ni/Mn-based layered oxides are promising cathode materials for sodium-ion batteries(SIBs)owing to their high energy density.However,exploring effective ways to enhance the synergy between the P2 and 03 phases remains a necessity.Herein,we design a P2/O3-type Na_(0.76)Ni_(0.31)Zn_(0.07)Mn_(0.50)Ti_(0.12)0_(2)(NNZMT)with high chemical/electrochemical stability by enhancing the coupling between the two phases.For the first time,a unique Na*extraction is observed from a Na-rich O3 phase by a Na-poor P2 phase and systematically investigated.This process is facilitated by Zn^(2+)/Ti^(4+)dual doping and calcination condition regulation,allowing a higher Na*content in the P2 phase with larger Na^(+)transport channels and enhancing Na transport kinetics.Because of reduced Na^(+)in the O3 phase,which increases the difficulty of H^(+)/Na^(+) exchange,the hydrostability of the O3 phase in NNZMT is considerably improved.Furthermore,Zn^(2+)/Ti^(4+)presence in NNZMT synergistically regulates oxygen redox chemistry,which effectively suppresses O_(2)/CO_(2) gas release and electrolyte decomposition,and completely inhibits phase transitions above 4.0 V.As a result,NNZMT achieves a high discharge capacity of 144.8 mA h g^(-1) with a median voltage of 3.42 V at 20 mA g^(-1) and exhibits excellent cycling performance with a capacity retention of 77.3% for 1000 cycles at 2000 mA g^(-1).This study provides an effective strategy and new insights into the design of high-performance layered-oxide cathode materials with enhanced structure/interface stability forSIBs.展开更多
BACKGROUND Accumulating clinical evidence has shown that diabetes mellitus(DM)is a serious risk factor for cardiovascular disorders and an important factor for adverse cardiovascular events.AIM To explore the value of...BACKGROUND Accumulating clinical evidence has shown that diabetes mellitus(DM)is a serious risk factor for cardiovascular disorders and an important factor for adverse cardiovascular events.AIM To explore the value of the combined determination of the neutrophil-lymphocyte ratio(NLR)and red blood cell distribution width(RDW)in the early diagnosis and prognosis evaluation of DM complicated with heart failure(HF).METHODS We retrospectively analyzed clinical data on 65 patients with type 2 DM(T2DM)complicated with HF(research group,Res)and 60 concurrent patients with uncomplicated T2DM(control group,Con)diagnosed at Zhejiang Provincial People’s Hospital between January 2019 and December 2021.The NLR and RDW values were determined and comparatively analyzed,and their levels in T2DM+HF patients with different cardiac function grades were recorded.The receiver operating characteristic(ROC)curves were plotted to determine the NLR and RDW values(alone and in combination)for the early diagnosis of HF.The correlation between NLR and RDW with the presence or absence of cardiac events was also investigated.RESULTS Higher NLR and RDW levels were identified in the Res vs the Con groups(P<0.05).The NLR and RDW increased gradually and synchronously with the deterioration of cardiac function in the Res group,with marked differences in their levels among patients with grade II,III,and IV HF(P<0.05).ROC curve analysis revealed that NLR combined with RDW detection had an area under the curve of 0.915,a sensitivity of 76.9%,and a specificity of 100%for the early diagnosis of HF.Furthermore,HF patients with cardiac events showed higher NLR and RDW values compared with HF patients without cardiac events.CONCLUSION NLR and RDW were useful laboratory indicators for the early diagnosis of DM complicated with HF,and their joint detection was beneficial for improving diagnostic efficiency.Additionally,NLR and RDW values were directly proportional to patient outcomes.展开更多
The 2D NMR(T_(1)-T_(2))mapping technique,which can be used to separate different proton populations from various sources(hydroxyls,solid organic matter,free water,and free HC)has gained attention in petroleum industry...The 2D NMR(T_(1)-T_(2))mapping technique,which can be used to separate different proton populations from various sources(hydroxyls,solid organic matter,free water,and free HC)has gained attention in petroleum industry.To separate proton contributions,a fixed straight line is commonly employed to separate different regions representing proton sources on the map.However,some of these regions(Region 1 and 2)might overlap which makes extracting the NMR signal amplitude from these regions inaccurate.In order to solve this issue,in this study,we applied the Gaussian distribution deconvolution method to separate the T_(1)and T_(2)relaxation distributions and then derived the signal amplitude of each region instead of following the common fixed line approach.Next,we employed this method to analyze several shale samples from the literature and compared the results following both methods to verify our methodology.Finally,samples from the Bakken Shale were studied to separate signals from Region 1 and Region 2 and corelated the results with geochemical properties that were obtained from programmed(Rock Eval)pyrolysis.Results demonstrated an improvement in their relation when our approach is employed compared to the fixed line technique to differentiate signal from overlapping regions.This means the Gaussian distribution deconvolution method can be used with confidence to provide us with more accurate petrophysical and geochemical understanding of complex formations.展开更多
To investigate the effect of low energy ion implantation on maize pollen germination and cytosolic Ca2+ distribution during pollen germination process, the argon ion (Ar+) with energy of 30 keV, dose of 0.78 ×101...To investigate the effect of low energy ion implantation on maize pollen germination and cytosolic Ca2+ distribution during pollen germination process, the argon ion (Ar+) with energy of 30 keV, dose of 0.78 ×1015-13×1015 ion/cm2 was implanted into maize pollen by irradiation, and the germination of pollen and cytosolic Ca2+ distribution during pollen germination process of the Ar+ implanted pollen were studied. The results showed that when been irradiated with Ar+ with dose of 5.2×1015 ion/cm2, the germination rate of maize pollen increased remarkably, while implantation of ions with dose exceeding 5.2×1015 ion/cm2 sharply decreased the germination rate of maize pollen. Meanwhile, tracing of esterified Ca2+ fluorescence probe fluo-3 AM for intact pollen showed that variation of cytosolic Ca2+ concentration was consistent with the change of pollen fertility. The dynamics of cytosolic Ca2+ concentration caused by low energy ion implantation may be concluded as the initial effects of pollen germination.展开更多
We built a three-dimensional irregular network model which can adequately describe reservoir rock pore-throat structures. We carried out numerical simulations to study the NMR T2 distribution of water-saturated rocks....We built a three-dimensional irregular network model which can adequately describe reservoir rock pore-throat structures. We carried out numerical simulations to study the NMR T2 distribution of water-saturated rocks. The results indicate that there is a good correlation between T2 distribution and the pore radius frequency histogram. The total T2 distribution can be partitioned into pore body and pore throat parts. The effect of parameters including throat radius, pore-throat ratio, and coordination number of the micro- pore structure on the T2 distribution can be evaluated individually. The result indicates that： 1 ） with the increase of the pore throat radius, the T2 distribution moves toward longer relaxation times and its peak intensity increases; 2） with the increase of the pore-throat ratio, the T2 distribution moves towards longer T2 with the peak intensity increasing and the overlap between pore body T2 and pore throat T2 decreasing; 3） With the increase of connectivity, the short T2 component increases and peak signal intensity decreases slightly.展开更多
In this paper, the authors generalize the definition of χ 2 distribution and introduce a quasi χ 2 distribution, and then prove several properties of it, find the necessary and sufficient conditions of i...In this paper, the authors generalize the definition of χ 2 distribution and introduce a quasi χ 2 distribution, and then prove several properties of it, find the necessary and sufficient conditions of independence about multivariate normal distributions, matrix normal distributions and two parts of the Wishart distribution.展开更多
目的探讨血小板、凝血功能对合并2型糖尿病的脓毒症(sepsis patients with type 2 diabetes mellitus,T2DM-sepsis)患者发生急性肾损伤(acute kidney injury,AKI)的预测价值。方法选取2015年1月至2021年1月首都医科大学附属北京同仁医院...目的探讨血小板、凝血功能对合并2型糖尿病的脓毒症(sepsis patients with type 2 diabetes mellitus,T2DM-sepsis)患者发生急性肾损伤(acute kidney injury,AKI)的预测价值。方法选取2015年1月至2021年1月首都医科大学附属北京同仁医院T2DM-sepsis患者257例。根据T2DM-sepsis患者住院期间脓毒症发病7 d内是否发生AKI,将患者分为AKI组与非AKI组。收集两组患者一般资料和临床资料,采用多因素logistic回归方程分析T2DM-sepsis患者发生AKI的影响因素,并采用ROC曲线评估血小板、凝血功能对患者发生AKI的预测价值。结果257例患者中男146例、女111例,年龄32~101岁,平均(77.4±13.2)岁;发生AKI的患者34例(13.2%)。与非AKI组相比,AKI组的序贯器官衰竭评估(sequential organ failure assessment,SOFA)评分、急性生理学和慢性健康状况评价Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评分、血小板分布宽度(platelet distribution width,PDW)、血小板平均体积(mean platelet volume,MPV)、纤维蛋白原降解产物(fibrinogen degradation products,FDP)和D-二聚体(D-dimer,D-D)均较高,PLT较低,差异均有统计学意义(P<0.05)。多因素回归分析结果显示,SOFA评分越高(OR=1.300,95%CI:1.018~1.661,P=0.035)、PDW越高(OR=1.338,95%CI:1.122~1.596,P=0.001)的T2DM-sepsis患者发生AKI的风险越高。SOFA评分和PDW预测患者发生AKI的AUC分别为0.717(95%CI:0.619~0.815,P<0.001)和0.752(95%CI:0.655~0.848,P<0.001)。结论PDW值可作为T2DM-sepsis患者发生AKI风险的评估指标,临床上应特别关注PDW>12.25 fl的T2DM-sepsis患者的治疗和预后。展开更多
针对火电机组SO_(2)排放质量浓度的影响因素众多,难以准确预测的问题,提出一种改进向量加权平均(weighted mean of vectors,INFO)算法与双向长短期记忆(bi-directional long short term memory,Bi-LSTM)神经网络相结合的预测模型(改进IN...针对火电机组SO_(2)排放质量浓度的影响因素众多,难以准确预测的问题,提出一种改进向量加权平均(weighted mean of vectors,INFO)算法与双向长短期记忆(bi-directional long short term memory,Bi-LSTM)神经网络相结合的预测模型(改进INFO-Bi-LSTM模型)。采用Circle混沌映射和反向学习产生高质量初始化种群,引入自适应t分布提升INFO算法跳出局部最优解和全局搜索的能力。选取改进INFO-Bi-LSTM模型和多种预测模型对炉内外联合脱硫过程中4种典型工况下的SO_(2)排放质量浓度进行预测,将预测结果进行验证对比。结果表明:改进INFO算法的寻优能力得到提升,并且改进INFO-Bi-LSTM模型精度更高,更加适用于SO_(2)排放质量浓度的预测,可为变工况下的脱硫控制提供控制理论支撑。展开更多
Wedge-shaped copper casting experiment was conducted to study the engulfment behavior of TiB2 particle and the interaction between particle or cluster and the solid/liquid front in commercial pure aluminum matrix. The...Wedge-shaped copper casting experiment was conducted to study the engulfment behavior of TiB2 particle and the interaction between particle or cluster and the solid/liquid front in commercial pure aluminum matrix. The experimental results show that the particle size distribution obeys two separate systems in the whole wedge-cast sample. Furthermore, it is found that the big clusters are pushed to the center of the wedge shaped sample and the single particle or small clusters consisting of few particles are engulfed into the α-Al in the area of the sample edge. The cluster degree of particles varies in different areas, and its value is 0.2 and 0.6 for the cluster fraction in the edge and in the center of the wedge sample, respectively. The cluster diameter does not obey the normal distribution but approximately obeys lognormal distribution in the present work. More importantly, in the whole sample, the particle size obeys two separate log-normal distributions.展开更多
We present the thorium distribution on the lunar surface derived from observations by the Chang’E-2 gamma-ray spectrometer(CE-2 GRS). This new map shows a similar thorium distribution to previous observations. In com...We present the thorium distribution on the lunar surface derived from observations by the Chang’E-2 gamma-ray spectrometer(CE-2 GRS). This new map shows a similar thorium distribution to previous observations. In combination with this new thorium map and impact cratering model, we investigate the origination of thorium on the Moon’s highlands, which was previously thought to be contributed from Imbrium ejecta. We found that the Imbrium ejecta has a small contribution(~20%–30%) to the thorium on the lunar highlands but most thorium is likely to be indigenous before the deposition of the Imbrium ejecta. This new thorium map also confirms that the eastern highlands have a relatively higher thorium concentration than the western highlands. We propose that the thin crust and large basins on the eastern highlands are responsible for this difference in thorium.展开更多
The CO2 adsorption data may show more than one section in the Dubinin-Radushkevich-Kaganer(DRK) plot if samples had been over-activated. Each section in the plot represents a range of pore size. The whole DRK plot pro...The CO2 adsorption data may show more than one section in the Dubinin-Radushkevich-Kaganer(DRK) plot if samples had been over-activated. Each section in the plot represents a range of pore size. The whole DRK plot provided information on the pore size distribution(PSD) of a sample, which may be used to monitor the effect of activation conditions in activation processes.展开更多
The presence of matrix metalloproteinase-2 （MMP-2） in dentin has been reported, but its distribution and activity level in mature human coronal dentin are not well understood. The purpose of this study was to determ...The presence of matrix metalloproteinase-2 （MMP-2） in dentin has been reported, but its distribution and activity level in mature human coronal dentin are not well understood. The purpose of this study was to determine the MMP-2 distribution and relative activity in demineralized dentin. Crowns of twenty eight human molars were sectioned into inner （ID）, middle （MD）, and outer dentin （OD） regions and demineralized. MMP-2 was extracted with 0.33 mol·L-1 EDTA/2 mol·L-1 guanidine-HCl, pH 7.4, and MMP-2 concentration was estimated with enzyme-linked immunoabsorbant assay （ELISA）. Further characterization was accomplished by Western blotting analysis and gelatin zymography. The mean concentrations of MMP-2 per mg dentin protein in the dentin regions were significantly different （P=0.043）： 0.9 ng （ID）, 0.4 ng （MD）, and 2.2 ng （OD）, respectively. The pattern of MMP-2 concentration was OD〉ID〉MD. Western blotting analysis detected -66 and -72 kDa immunopositive proteins corresponding to pro- and mature MMP-2, respectively, in the ID and MD, and a -66 kDa protein in the OD. Gelatinolytic activity consistent with MMP-2 was detected in all regions. Interestingly, the pattern of levels of Western blot immunodetection and gelatinolytic activity was MD〉ID〉OD. The eoneentration of MMP-2 in human coronal dentin was highest in the region of dentin that contains the dentinoenamel junction and least in the middle region of dentin. However, levels of Western blot immunodetection and gelatinolytic activity did not correlate with the estimated regional concentrations of MMP-2, potentially indicating region specific protein interactions.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.51708078)Natural Science Foundation of Chongqing(Grant No.CSTB2022NSCQ-MSX0815)+2 种基金Science and Technology Research Program of Chongqing Municipal Education Commission(Grant No.KJQN202200542)the Chongqing Innovative Research Group Project(Grant No.CXQT21015)Foundation of Chongqing Normal University(22XLB022).
文摘Photocatalytic CO_(2)reduction to produce high value-added carbon-based fuel has been proposed as a promising approach to mitigate global warming issues.However,the conversion efficiency and product selectivity are still low due to the sluggish dynamics of transfer processes involved in proton-assisted multi-electron reactions.Lowering the formation energy barriers of intermediate products is an effective method to enhance the selectivity and productivity of final products.In this study,we aim to regulate the surface electronic structure of Bi_(2)WO_(6)by doping surface chlorine atoms to achieve effective photocatalytic CO_(2)reduction.Surface Cl atoms can enhance the absorption ability of light,affect its energy band structure and promote charge separation.Combined with DFT calculations,it is revealed that surface Cl atoms can not only change the surface charge distribution which affects the competitive adsorption of H_(2)O and CO_(2),but also lower the formation energy barrier of intermediate products to generate more intermediate*COOH,thus facilitating CO production.Overall,this study demonstrates a promising surface halogenation strategy to enhance the photocatalytic CO_(2)reduction activity of a layered structure Bi-based catalyst.
基金supported by the National Natural Science Foundation of China (22169002)the Chongzuo Key Research and Development Program of China (20220603)the Counterpart Aid Project for Discipline Construction from Guangxi University(2023M02)
文摘P2/O3-type Ni/Mn-based layered oxides are promising cathode materials for sodium-ion batteries(SIBs)owing to their high energy density.However,exploring effective ways to enhance the synergy between the P2 and 03 phases remains a necessity.Herein,we design a P2/O3-type Na_(0.76)Ni_(0.31)Zn_(0.07)Mn_(0.50)Ti_(0.12)0_(2)(NNZMT)with high chemical/electrochemical stability by enhancing the coupling between the two phases.For the first time,a unique Na*extraction is observed from a Na-rich O3 phase by a Na-poor P2 phase and systematically investigated.This process is facilitated by Zn^(2+)/Ti^(4+)dual doping and calcination condition regulation,allowing a higher Na*content in the P2 phase with larger Na^(+)transport channels and enhancing Na transport kinetics.Because of reduced Na^(+)in the O3 phase,which increases the difficulty of H^(+)/Na^(+) exchange,the hydrostability of the O3 phase in NNZMT is considerably improved.Furthermore,Zn^(2+)/Ti^(4+)presence in NNZMT synergistically regulates oxygen redox chemistry,which effectively suppresses O_(2)/CO_(2) gas release and electrolyte decomposition,and completely inhibits phase transitions above 4.0 V.As a result,NNZMT achieves a high discharge capacity of 144.8 mA h g^(-1) with a median voltage of 3.42 V at 20 mA g^(-1) and exhibits excellent cycling performance with a capacity retention of 77.3% for 1000 cycles at 2000 mA g^(-1).This study provides an effective strategy and new insights into the design of high-performance layered-oxide cathode materials with enhanced structure/interface stability forSIBs.
基金Supported by Zhejiang Province Traditional Chinese Medicine Science and 158 Technology Project,No.2023ZL008.
文摘BACKGROUND Accumulating clinical evidence has shown that diabetes mellitus(DM)is a serious risk factor for cardiovascular disorders and an important factor for adverse cardiovascular events.AIM To explore the value of the combined determination of the neutrophil-lymphocyte ratio(NLR)and red blood cell distribution width(RDW)in the early diagnosis and prognosis evaluation of DM complicated with heart failure(HF).METHODS We retrospectively analyzed clinical data on 65 patients with type 2 DM(T2DM)complicated with HF(research group,Res)and 60 concurrent patients with uncomplicated T2DM(control group,Con)diagnosed at Zhejiang Provincial People’s Hospital between January 2019 and December 2021.The NLR and RDW values were determined and comparatively analyzed,and their levels in T2DM+HF patients with different cardiac function grades were recorded.The receiver operating characteristic(ROC)curves were plotted to determine the NLR and RDW values(alone and in combination)for the early diagnosis of HF.The correlation between NLR and RDW with the presence or absence of cardiac events was also investigated.RESULTS Higher NLR and RDW levels were identified in the Res vs the Con groups(P<0.05).The NLR and RDW increased gradually and synchronously with the deterioration of cardiac function in the Res group,with marked differences in their levels among patients with grade II,III,and IV HF(P<0.05).ROC curve analysis revealed that NLR combined with RDW detection had an area under the curve of 0.915,a sensitivity of 76.9%,and a specificity of 100%for the early diagnosis of HF.Furthermore,HF patients with cardiac events showed higher NLR and RDW values compared with HF patients without cardiac events.CONCLUSION NLR and RDW were useful laboratory indicators for the early diagnosis of DM complicated with HF,and their joint detection was beneficial for improving diagnostic efficiency.Additionally,NLR and RDW values were directly proportional to patient outcomes.
基金support from the National Natural Science Foundation of China(42090020,42090025,42272150)the Sinopec Science and Technology Department(No.P20049-1).
文摘The 2D NMR(T_(1)-T_(2))mapping technique,which can be used to separate different proton populations from various sources(hydroxyls,solid organic matter,free water,and free HC)has gained attention in petroleum industry.To separate proton contributions,a fixed straight line is commonly employed to separate different regions representing proton sources on the map.However,some of these regions(Region 1 and 2)might overlap which makes extracting the NMR signal amplitude from these regions inaccurate.In order to solve this issue,in this study,we applied the Gaussian distribution deconvolution method to separate the T_(1)and T_(2)relaxation distributions and then derived the signal amplitude of each region instead of following the common fixed line approach.Next,we employed this method to analyze several shale samples from the literature and compared the results following both methods to verify our methodology.Finally,samples from the Bakken Shale were studied to separate signals from Region 1 and Region 2 and corelated the results with geochemical properties that were obtained from programmed(Rock Eval)pyrolysis.Results demonstrated an improvement in their relation when our approach is employed compared to the fixed line technique to differentiate signal from overlapping regions.This means the Gaussian distribution deconvolution method can be used with confidence to provide us with more accurate petrophysical and geochemical understanding of complex formations.
基金Supported by National Natural Science Foundation of China(10675002)~~
文摘To investigate the effect of low energy ion implantation on maize pollen germination and cytosolic Ca2+ distribution during pollen germination process, the argon ion (Ar+) with energy of 30 keV, dose of 0.78 ×1015-13×1015 ion/cm2 was implanted into maize pollen by irradiation, and the germination of pollen and cytosolic Ca2+ distribution during pollen germination process of the Ar+ implanted pollen were studied. The results showed that when been irradiated with Ar+ with dose of 5.2×1015 ion/cm2, the germination rate of maize pollen increased remarkably, while implantation of ions with dose exceeding 5.2×1015 ion/cm2 sharply decreased the germination rate of maize pollen. Meanwhile, tracing of esterified Ca2+ fluorescence probe fluo-3 AM for intact pollen showed that variation of cytosolic Ca2+ concentration was consistent with the change of pollen fertility. The dynamics of cytosolic Ca2+ concentration caused by low energy ion implantation may be concluded as the initial effects of pollen germination.
文摘We built a three-dimensional irregular network model which can adequately describe reservoir rock pore-throat structures. We carried out numerical simulations to study the NMR T2 distribution of water-saturated rocks. The results indicate that there is a good correlation between T2 distribution and the pore radius frequency histogram. The total T2 distribution can be partitioned into pore body and pore throat parts. The effect of parameters including throat radius, pore-throat ratio, and coordination number of the micro- pore structure on the T2 distribution can be evaluated individually. The result indicates that： 1 ） with the increase of the pore throat radius, the T2 distribution moves toward longer relaxation times and its peak intensity increases; 2） with the increase of the pore-throat ratio, the T2 distribution moves towards longer T2 with the peak intensity increasing and the overlap between pore body T2 and pore throat T2 decreasing; 3） With the increase of connectivity, the short T2 component increases and peak signal intensity decreases slightly.
文摘In this paper, the authors generalize the definition of χ 2 distribution and introduce a quasi χ 2 distribution, and then prove several properties of it, find the necessary and sufficient conditions of independence about multivariate normal distributions, matrix normal distributions and two parts of the Wishart distribution.
文摘目的探讨血小板、凝血功能对合并2型糖尿病的脓毒症(sepsis patients with type 2 diabetes mellitus,T2DM-sepsis)患者发生急性肾损伤(acute kidney injury,AKI)的预测价值。方法选取2015年1月至2021年1月首都医科大学附属北京同仁医院T2DM-sepsis患者257例。根据T2DM-sepsis患者住院期间脓毒症发病7 d内是否发生AKI,将患者分为AKI组与非AKI组。收集两组患者一般资料和临床资料,采用多因素logistic回归方程分析T2DM-sepsis患者发生AKI的影响因素,并采用ROC曲线评估血小板、凝血功能对患者发生AKI的预测价值。结果257例患者中男146例、女111例,年龄32~101岁,平均(77.4±13.2)岁;发生AKI的患者34例(13.2%)。与非AKI组相比,AKI组的序贯器官衰竭评估(sequential organ failure assessment,SOFA)评分、急性生理学和慢性健康状况评价Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评分、血小板分布宽度(platelet distribution width,PDW)、血小板平均体积(mean platelet volume,MPV)、纤维蛋白原降解产物(fibrinogen degradation products,FDP)和D-二聚体(D-dimer,D-D)均较高,PLT较低,差异均有统计学意义(P<0.05)。多因素回归分析结果显示,SOFA评分越高(OR=1.300,95%CI:1.018~1.661,P=0.035)、PDW越高(OR=1.338,95%CI:1.122~1.596,P=0.001)的T2DM-sepsis患者发生AKI的风险越高。SOFA评分和PDW预测患者发生AKI的AUC分别为0.717(95%CI:0.619~0.815,P<0.001)和0.752(95%CI:0.655~0.848,P<0.001)。结论PDW值可作为T2DM-sepsis患者发生AKI风险的评估指标,临床上应特别关注PDW>12.25 fl的T2DM-sepsis患者的治疗和预后。
文摘针对火电机组SO_(2)排放质量浓度的影响因素众多,难以准确预测的问题,提出一种改进向量加权平均(weighted mean of vectors,INFO)算法与双向长短期记忆(bi-directional long short term memory,Bi-LSTM)神经网络相结合的预测模型(改进INFO-Bi-LSTM模型)。采用Circle混沌映射和反向学习产生高质量初始化种群,引入自适应t分布提升INFO算法跳出局部最优解和全局搜索的能力。选取改进INFO-Bi-LSTM模型和多种预测模型对炉内外联合脱硫过程中4种典型工况下的SO_(2)排放质量浓度进行预测,将预测结果进行验证对比。结果表明:改进INFO算法的寻优能力得到提升,并且改进INFO-Bi-LSTM模型精度更高,更加适用于SO_(2)排放质量浓度的预测,可为变工况下的脱硫控制提供控制理论支撑。
文摘Wedge-shaped copper casting experiment was conducted to study the engulfment behavior of TiB2 particle and the interaction between particle or cluster and the solid/liquid front in commercial pure aluminum matrix. The experimental results show that the particle size distribution obeys two separate systems in the whole wedge-cast sample. Furthermore, it is found that the big clusters are pushed to the center of the wedge shaped sample and the single particle or small clusters consisting of few particles are engulfed into the α-Al in the area of the sample edge. The cluster degree of particles varies in different areas, and its value is 0.2 and 0.6 for the cluster fraction in the edge and in the center of the wedge sample, respectively. The cluster diameter does not obey the normal distribution but approximately obeys lognormal distribution in the present work. More importantly, in the whole sample, the particle size obeys two separate log-normal distributions.
基金supported by the National Natural Science Foundation of China(11773087)the Science and Technology Development Fund of Macao(079/2018/A2)
文摘We present the thorium distribution on the lunar surface derived from observations by the Chang’E-2 gamma-ray spectrometer(CE-2 GRS). This new map shows a similar thorium distribution to previous observations. In combination with this new thorium map and impact cratering model, we investigate the origination of thorium on the Moon’s highlands, which was previously thought to be contributed from Imbrium ejecta. We found that the Imbrium ejecta has a small contribution(~20%–30%) to the thorium on the lunar highlands but most thorium is likely to be indigenous before the deposition of the Imbrium ejecta. This new thorium map also confirms that the eastern highlands have a relatively higher thorium concentration than the western highlands. We propose that the thin crust and large basins on the eastern highlands are responsible for this difference in thorium.
基金Supported by the National Natural Science Foundation of China(No.29936100).
文摘The CO2 adsorption data may show more than one section in the Dubinin-Radushkevich-Kaganer(DRK) plot if samples had been over-activated. Each section in the plot represents a range of pore size. The whole DRK plot provided information on the pore size distribution(PSD) of a sample, which may be used to monitor the effect of activation conditions in activation processes.
文摘The presence of matrix metalloproteinase-2 （MMP-2） in dentin has been reported, but its distribution and activity level in mature human coronal dentin are not well understood. The purpose of this study was to determine the MMP-2 distribution and relative activity in demineralized dentin. Crowns of twenty eight human molars were sectioned into inner （ID）, middle （MD）, and outer dentin （OD） regions and demineralized. MMP-2 was extracted with 0.33 mol·L-1 EDTA/2 mol·L-1 guanidine-HCl, pH 7.4, and MMP-2 concentration was estimated with enzyme-linked immunoabsorbant assay （ELISA）. Further characterization was accomplished by Western blotting analysis and gelatin zymography. The mean concentrations of MMP-2 per mg dentin protein in the dentin regions were significantly different （P=0.043）： 0.9 ng （ID）, 0.4 ng （MD）, and 2.2 ng （OD）, respectively. The pattern of MMP-2 concentration was OD〉ID〉MD. Western blotting analysis detected -66 and -72 kDa immunopositive proteins corresponding to pro- and mature MMP-2, respectively, in the ID and MD, and a -66 kDa protein in the OD. Gelatinolytic activity consistent with MMP-2 was detected in all regions. Interestingly, the pattern of levels of Western blot immunodetection and gelatinolytic activity was MD〉ID〉OD. The eoneentration of MMP-2 in human coronal dentin was highest in the region of dentin that contains the dentinoenamel junction and least in the middle region of dentin. However, levels of Western blot immunodetection and gelatinolytic activity did not correlate with the estimated regional concentrations of MMP-2, potentially indicating region specific protein interactions.
