The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to fu...The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to function without disease,whereas dysbiosis has long-standing evidence of etiopathological conditions.The most common communication paths are the microbial release of metabolites,soluble neurotransmitters,and immune cells.However,each pathway is intertwined with a complex one.With the emergence of in vitro models and the popularity of three-dimensional(3D)cultures and Transwells,engineering has become easier for the scientific understanding of neurodegenerative diseases.This paper briefly retraces the possible communication pathways between the gut microbiome and the brain.It further elaborates on three major diseases:autism spectrum disorder,Parkinson’s disease,and Alzheimer’s disease,which are prevalent in children and the elderly.These diseases also decrease patients’quality of life.Hence,understanding them more deeply with respect to current advances in in vitro modeling is crucial for understanding the diseases.Remodeling of MGBA in the laboratory uses many molecular technologies and biomaterial advances.Spheroids and organoids provide a more realistic picture of the cell and tissue structure than monolayers.Combining them with the Transwell system offers the advantage of compartmentalizing the two systems(apical and basal)while allowing physical and chemical cues between them.Cutting-edge technologies,such as bioprinting and microfluidic chips,might be the future of in vitro modeling,as they provide dynamicity.展开更多
Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transp...Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transportationsystem. The movement of vehicles and the three-dimensional (3D) nature of the road network cause the topologicalstructure of IoV to have the high space and time complexity.Network modeling and structure recognition for 3Droads can benefit the description of topological changes for IoV. This paper proposes a 3Dgeneral roadmodel basedon discrete points of roads obtained from GIS. First, the constraints imposed by 3D roads on moving vehicles areanalyzed. Then the effects of road curvature radius (Ra), longitudinal slope (Slo), and length (Len) on speed andacceleration are studied. Finally, a general 3D road network model based on road section features is established.This paper also presents intersection and road section recognition methods based on the structural features ofthe 3D road network model and the road features. Real GIS data from a specific region of Beijing is adopted tocreate the simulation scenario, and the simulation results validate the general 3D road network model and therecognitionmethod. Therefore, thiswork makes contributions to the field of intelligent transportation by providinga comprehensive approach tomodeling the 3Droad network and its topological changes in achieving efficient trafficflowand improved road safety.展开更多
Facial wound segmentation plays a crucial role in preoperative planning and optimizing patient outcomes in various medical applications.In this paper,we propose an efficient approach for automating 3D facial wound seg...Facial wound segmentation plays a crucial role in preoperative planning and optimizing patient outcomes in various medical applications.In this paper,we propose an efficient approach for automating 3D facial wound segmentation using a two-stream graph convolutional network.Our method leverages the Cir3D-FaIR dataset and addresses the challenge of data imbalance through extensive experimentation with different loss functions.To achieve accurate segmentation,we conducted thorough experiments and selected a high-performing model from the trainedmodels.The selectedmodel demonstrates exceptional segmentation performance for complex 3D facial wounds.Furthermore,based on the segmentation model,we propose an improved approach for extracting 3D facial wound fillers and compare it to the results of the previous study.Our method achieved a remarkable accuracy of 0.9999993% on the test suite,surpassing the performance of the previous method.From this result,we use 3D printing technology to illustrate the shape of the wound filling.The outcomes of this study have significant implications for physicians involved in preoperative planning and intervention design.By automating facial wound segmentation and improving the accuracy ofwound-filling extraction,our approach can assist in carefully assessing and optimizing interventions,leading to enhanced patient outcomes.Additionally,it contributes to advancing facial reconstruction techniques by utilizing machine learning and 3D bioprinting for printing skin tissue implants.Our source code is available at https://github.com/SIMOGroup/WoundFilling3D.展开更多
Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Ou...Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Our review traces the evolution of CNN, emphasizing the adaptation and capabilities of the U-Net 3D model in automating seismic fault delineation with unprecedented accuracy. We find: 1) The transition from basic neural networks to sophisticated CNN has enabled remarkable advancements in image recognition, which are directly applicable to analyzing seismic data. The U-Net 3D model, with its innovative architecture, exemplifies this progress by providing a method for detailed and accurate fault detection with reduced manual interpretation bias. 2) The U-Net 3D model has demonstrated its superiority over traditional fault identification methods in several key areas: it has enhanced interpretation accuracy, increased operational efficiency, and reduced the subjectivity of manual methods. 3) Despite these achievements, challenges such as the need for effective data preprocessing, acquisition of high-quality annotated datasets, and achieving model generalization across different geological conditions remain. Future research should therefore focus on developing more complex network architectures and innovative training strategies to refine fault identification performance further. Our findings confirm the transformative potential of deep learning, particularly CNN like the U-Net 3D model, in geosciences, advocating for its broader integration to revolutionize geological exploration and seismic analysis.展开更多
Building model data organization is often programmed to solve a specific problem,resulting in the inability to organize indoor and outdoor 3D scenes in an integrated manner.In this paper,existing building spatial data...Building model data organization is often programmed to solve a specific problem,resulting in the inability to organize indoor and outdoor 3D scenes in an integrated manner.In this paper,existing building spatial data models are studied,and the characteristics of building information modeling standards(IFC),city geographic modeling language(CityGML),indoor modeling language(IndoorGML),and other models are compared and analyzed.CityGML and IndoorGML models face challenges in satisfying diverse application scenarios and requirements due to limitations in their expression capabilities.It is proposed to combine the semantic information of the model objects to effectively partition and organize the indoor and outdoor spatial 3D model data and to construct the indoor and outdoor data organization mechanism of“chunk-layer-subobject-entrances-area-detail object.”This method is verified by proposing a 3D data organization method for indoor and outdoor space and constructing a 3D visualization system based on it.展开更多
Mining industrial areas with anthropogenic engineering structures are one of the most distinctive features of the real world.3D models of the real world have been increasingly popular with numerous applications,such a...Mining industrial areas with anthropogenic engineering structures are one of the most distinctive features of the real world.3D models of the real world have been increasingly popular with numerous applications,such as digital twins and smart factory management.In this study,3D models of mining engineering structures were built based on the CityGML standard.For collecting spatial data,the two most popular geospatial technologies,namely UAV-SfM and TLS were employed.The accuracy of the UAV survey was at the centimeter level,and it satisfied the absolute positional accuracy requirement of creat-ing all levels of detail(LoD)according to the CityGML standard.Therefore,the UAV-SfM point cloud dataset was used to build LoD 2 models.In addition,the comparison between the UAV-SfM and TLS sub-clouds of facades and roofs indicates that the UAV-SfM and TLS point clouds of these objects are highly consistent,therefore,point clouds with a higher level of detail and accuracy provided by the integration of UAV-SfM and TLS were used to build LoD 3 models.The resulting 3D CityGML models include 39 buildings at LoD 2,and two mine shafts with hoistrooms,headframes,and sheave wheels at LoD3.展开更多
Background With the rapid development of Web3D technologies, the online Web3D visualization, particularly for complex models or scenes, has been in a great demand. Owing to the major conflict between the Web3D system ...Background With the rapid development of Web3D technologies, the online Web3D visualization, particularly for complex models or scenes, has been in a great demand. Owing to the major conflict between the Web3D system load and resource consumption in the processing of these huge models, the huge 3D model lightweighting methods for online Web3D visualization are reviewed in this paper. Methods By observing the geometry redundancy introduced by man-made operations in the modeling procedure, several categories of light-weighting related work that aim at reducing the amount of data and resource consumption are elaborated for Web3D visualization. Results By comparing perspectives, the characteristics of each method are summarized, and among the reviewed methods, the geometric redundancy removal that achieves the lightweight goal by detecting and removing the repeated components is an appropriate method for current online Web3D visualization. Meanwhile, the learning algorithm, still in improvement period at present, is our expected future research topic. Conclusions Various aspects should be considered in an efficient lightweight method for online Web3D visualization, such as characteristics of original data, combination or extension of existing methods, scheduling strategy, cache man-agement, and rendering mechanism. Meanwhile, innovation methods, particularly the learning algorithm, are worth exploring.展开更多
The mechanical characteristics of crystalline rocks are affected by the heterogeneity of the spatial distribution of minerals.In this paper,a novel three-dimensional(3D)grain-based model(GBM)based on particle flow cod...The mechanical characteristics of crystalline rocks are affected by the heterogeneity of the spatial distribution of minerals.In this paper,a novel three-dimensional(3D)grain-based model(GBM)based on particle flow code(PFC),i.e.PFC3D-GBM,is proposed.This model can accomplish the grouping of mineral grains at the 3D scale and then filling them.Then,the effect of the position distribution,geometric size,and volume composite of mineral grains on the cracking behaviour and macroscopic properties of granite are examined by conducting Brazilian splitting tests.The numerical results show that when an external load is applied to a sample,force chains will form around each contact,and the orientation distribution of the force chains is uniform,which is independent of the external load level.Furthermore,the number of high-strength force chains is proportional to the external load level,and the main orientation distribution is consistent with the external loading direction.The main orientation of the cracks is vertical to that of the high-strength force chains.The geometric size of the mineral grains controls the mechanical behaviours.As the average grain size increases,the number of transgranular contacts with higher bonding strength in the region connecting both loading points increases.The number of high-strength force chains increases,leading to an increase in the stress concentration value required for the macroscopic failure of the sample.Due to the highest bonding strength,the generation of transgranular cracks in quartz requires a higher concentrated stress value.With increasing volume composition of quartz,the number of transgranular cracks in quartz distributed in the region connecting both loading points increases,which requires many high-strength force chains.The load level rises,leading to an increase in the tensile strength of the numerical sample.展开更多
BACKGROUND Duodenum-preserving pancreatic head resection(DPPHR)is the choice of surgery for benign or low-grade malignant tumors of the pancreatic head.Laparoscopic DPPHR(LDPPHR)procedure can be improved by preoperati...BACKGROUND Duodenum-preserving pancreatic head resection(DPPHR)is the choice of surgery for benign or low-grade malignant tumors of the pancreatic head.Laparoscopic DPPHR(LDPPHR)procedure can be improved by preoperative 3D model reconstruction and the use of intravenous indocyanine green fluorescent before surgery for real-time navigation with fluorescent display to guide the surgical dissection and prevention of from injury to vessels and biliary tract.CASE SUMMARY Here we report the successful short-and long-term outcomes after one year following LDPPHR for a 60-year lady who had an uneventful recovery and was discharged home one week after the surgery.CONCLUSION There was no bile leakage or pancreatic leakage or delayed gastric emptying.The histopathology report showed multiple cysts in the pancreatic head and localized pancreatic intraepithelial tumor lesions.The resected margin was free of tumor.展开更多
Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error...Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error detection and dynamic correction in 3D geological structure models,we have reviewed the current situation and development trends in 3D geological modeling.The main context of uncertainty in 3D geological structure models is discussed.Major research issues and a general framework system of uncertainty in 3D geological structure models are proposed.We have described in detail the integration of development practices of 3D geological modeling systems,as well as the implementation process for uncertainty evaluation in 3D geological structure models.This study has laid the basis to build theoretical and methodological systems for accuracy assessment and error correction in 3D geological models and can assist in improving 3D modeling techniques under complex geological conditions.展开更多
To improve the accuracy of indirect tensile strength for a transversely isotropic rock in the Brazilian test, this study considered the three-dimensional (3D) deformation and the nonlinear stress–strain relationship....To improve the accuracy of indirect tensile strength for a transversely isotropic rock in the Brazilian test, this study considered the three-dimensional (3D) deformation and the nonlinear stress–strain relationship. A parametric study of a numerical Brazilian test was performed for a general range of elastic constants, revealing that the 3D modeling evaluated the indirect tensile strength up to 40% higher than the plane stress modeling. For the actual Asan gneiss, the 3D model evaluated the indirect tensile strength up to 10% higher and slightly enhanced the accuracy of deformation estimation compared with the plane stress model. The nonlinearity in stress–strain curve of Asan gneiss under uniaxial compression was then considered, such that the evaluated indirect tensile strength was affected by up to 10% and its anisotropy agreed well with the physical intuition. The estimation of deformation was significantly enhanced. The further validation on the nonlinear model is expected as future research.展开更多
To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D mode...To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D modeling to DTs modeling is analyzed,as well as the current application of DTs modeling in various industries.The application of 3D DTs modeling in theelds of smartmanufacturing,smart ecology,smart transportation,and smart buildings in smart cities is analyzed in detail,and the current limitations are summarized.It is found that the 3D modeling technology in DTs has broad prospects for development and has a huge impact on all walks of life and even human lifestyles.At the same time,the development of DTs modeling relies on the development and support capabilities of mature technologies such as Big Data,Internet of Things,Cloud Computing,Articial Intelligence,and game technology.Therefore,although some results have been achieved,there are still limitations.This work aims to provide a good theoretical support for the further development of 3D DTs modeling.展开更多
The formation heterogeneity is considered as one of the major factors limiting the application of foam flooding.In this paper,influences of formation properties,such as permeability,permeability distribution,interlaye...The formation heterogeneity is considered as one of the major factors limiting the application of foam flooding.In this paper,influences of formation properties,such as permeability,permeability distribution,interlayer,sedimentary rhythm and 3D heterogeneity,on the mobility control capability and oil displacement efficiency of foam flooding,were systematically investigated using 2D homogeneous and 2D/3D heterogeneous models under 120°C and salinity of 20×10~4 mg/L.The flow resistance of foam was promoted as the permeability increased,which thus resulted in a considerable oil recovery behavior.In the scenario of the vertical heterogeneous formations,it was observed that the permeability of the high-permeable layer was crucial to foam mobility control,and the positive rhythm appeared favorable to improve the foam flooding performance.The additional oil recovery increased to about 40%.The interlayer was favorable for the increases in mobility reduction factor and oil recovery of foam flooding when the low permeability ratio was involved.For the 3D heterogeneous formations,foam could efficiently adjust the areal and vertical heterogeneity through mobility control and gravity segregation,and thus enhancing the oil recovery to 11%–14%.The results derived from this work may provide some insight for the field test designs of foam flooding.展开更多
Background:Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment outcomes.The introduction of this technique into pediatric cardiac...Background:Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment outcomes.The introduction of this technique into pediatric cardiac surgery will allow us to study features of the anatomy and spatial relations of a defect and to simulate the optimal surgical repair on a printed model in every individual case.Methods:We performed the prospective cohort study which included 29 children with congenital heart defects.The hearts and the great vessels were modeled and printed out.Measurements of the same cardiac areas were taken in the same planes and points at multislice computed tomography images(group 1)and on printed 3D models of the hearts(group 2).Pre-printing treatment of the multislice computed tomography data and 3D model preparation were performed according to a newly developed algorithm.Results:The measurements taken on the 3D-printed cardiac models and the tomographic images did not differ significantly,which allowed us to conclude that the models were highly accurate and informative.The new algorithm greatly simplifies and speeds up the preparation of a 3D model for printing,while maintaining high accuracy and level of detail.Conclusions:The 3D-printed models provide an accurate preoperative assessment of the anatomy of a defect in each case.The new algorithm has several important advantages over other available programs.They enable the development of customized preliminary plans for surgical repair of each specific complex congenital heart disease,predict possible issues,determine the optimal surgical tactics,and significantly improve surgical outcomes.展开更多
Nowadays,Web browsers have become an important carrier of 3D model visualization because of their convenience and portability.During the process of large-scale 3D model visualization based on Web scenes with the probl...Nowadays,Web browsers have become an important carrier of 3D model visualization because of their convenience and portability.During the process of large-scale 3D model visualization based on Web scenes with the problems of slow rendering speed and low FPS(Frames Per Second),occlusion culling,as an important method for rendering optimization,can remove most of the occluded objects and improve rendering efficiency.The traditional occlusion culling algorithm(TOCA)is calculated by traversing all objects in the scene,which involves a large amount of repeated calculation and time consumption.To advance the rendering process and enhance rendering efficiency,this paper proposes an occlusion culling with three different optimization methods based on the WebGPU Computing Pipeline.Firstly,for the problem of large amounts of repeated calculation processes in TOCA,these units are moved from the CPU to the GPU for parallel computing,thereby accelerating the calculation of the Potential Visible Sets(PVS);Then,for the huge overhead of creating pipeline caused by too many 3D models in a certain scene,the Breaking Occlusion Culling Algorithm(BOCA)is introduced,which removes some nodes according to building a Hierarchical Bounding Volume(BVH)scene tree to reduce the overhead of creating pipelines;After that,the structure of the scene tree is transmitted to the GPU in the order of depth-first traversal and finally,the PVS is obtained by parallel computing.In the experiments,3D geological models with five different scales from 1:5,000 to 1:500,000 are used for testing.The results show that the proposed methods can reduce the time overhead of repeated calculation caused by the computing pipeline creation and scene tree recursive traversal in the occlusion culling algorithm effectively,with 97%rendering efficiency improvement compared with BOCA,thereby accelerating the rendering process on Web browsers.展开更多
The acquisition of digital regional-scale information and ecological environmental data has high requirements for structural texture,spatial res-olution,and multiple parameter categories,which is challenging to achiev...The acquisition of digital regional-scale information and ecological environmental data has high requirements for structural texture,spatial res-olution,and multiple parameter categories,which is challenging to achieve using satellite remote sensing.Considering the convenient,facilitative,and flexible characteristics of UAV(unmanned air vehicle)remote sensing tech-nology,this study selects a campus as a typical research area and uses the Pegasus D2000 equipped with a D-MSPC2000 multi-spectral camera and a CAM3000 aerial camera to acquire oblique images and multi-spectral data.Using professional software,including Context Capture,ENVI,and ArcGIS,a 3D(three-dimensional)campus model,a digital orthophoto map,and multi-spectral remote sensing map drawing are realized,and the geometric accuracy of typical feature selection is evaluated.Based on a quantitative remote sensing model,the campus ecological environment assessment is performed from the perspectives of vegetation and water body.The results presented in this study could be of great significance to the scientific management and sustainable development of regional natural resources.展开更多
This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of com...This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of complex frequency-shifted perfectly matched layer(CFS-PML)was used for truncation so that the low-frequency electromagnetic wave can be better absorbed at the model boundary.A typical three-dimensional(3D)homogeneous half-space model was established and a low-resistivity cube model was analyzed under the half-space condition.The response patterns and drivers of the low-resistivity cube model were discussed under the influence of a low-resistivity overburden.The absorption boundary conditions of CFS-PML significantly affected the low-frequency electromagnetic waves.For a low-resistivity cube around the borehole,its response curve exhibited a single-peak,and the extreme point of the curve corresponded to the center of the low-resistivity body.When the low-resistivity cube was directly below the borehole,the response curve showed three extreme values(two high and one low),with the low corresponding to the center of the low-resistivity body.The total field response of the low-resistivity overburden was stronger than that of the uniform half-space model due to the low-resistivity shielding effect of electromagnetic waves.When the receiving-transmitting distance gradually increased,the effect of the low-resistivity overburden was gradually weakened,and the response of the low-resistivity cube was strengthened.It was affected by the ratio of the overburden resistivity to the resistivity of the low-resistivity body.展开更多
A grain-based distinct element model featuring three-dimensional (3D) Voronoi tessellations (randompoly-crystals) is proposed for simulation of crack damage development in brittle rocks. The grainboundaries in pol...A grain-based distinct element model featuring three-dimensional (3D) Voronoi tessellations (randompoly-crystals) is proposed for simulation of crack damage development in brittle rocks. The grainboundaries in poly-crystal structure produced by Voronoi tessellations can represent flaws in intact rockand allow for numerical replication of crack damage progression through initiation and propagation ofmicro-fractures along grain boundaries. The Voronoi modelling scheme has been used widely in the pastfor brittle fracture simulation of rock materials. However the difficulty of generating 3D Voronoi modelshas limited its application to two-dimensional (2D) codes. The proposed approach is implemented inNeper, an open-source engine for generation of 3D Voronoi grains, to generate block geometry files thatcan be read directly into 3DEC. A series of Unconfined Compressive Strength (UCS) tests are simulated in3DEC to verify the proposed methodology for 3D simulation of brittle fractures and to investigate therelationship between each micro-parameter and the model's macro-response. The possibility of numericalreplication of the classical U-shape strength curve for anisotropic rocks is also investigated innumerical UCS tests by using complex-shaped (elongated) grains that are cemented to one another alongtheir adjoining sides. A micro-parameter calibration procedure is established for 3D Voronoi models foraccurate replication of the mechanical behaviour of isotropic and anisotropic (containing a fabric) rocks. 2014 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.展开更多
This study proposes a detailed concept of how landscape changes can be transferred and communicated in a 3D environment using the storytelling approach. In 2018, Mocnik and Fairbairn argued that maps are good for repr...This study proposes a detailed concept of how landscape changes can be transferred and communicated in a 3D environment using the storytelling approach. In 2018, Mocnik and Fairbairn argued that maps are good for representing a geographic space but texts have a better benefit than maps for telling a story [1]. A framework is presented on how a landscape change can be retrieved out of textual descriptions. A prototype of a 3D model with a projection on top of it was developed. The case study tells the story of the landscape change in the city of Pristina. The key element of the visualization is a timeline. Several media like cadastral maps, orthophotos, texts, graphics, and background sound are used and combined in an animated light show and the visualization was evaluated within a user study.展开更多
A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite...A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite based on the electrical resistivity methods. The combination of electrical trailing, sounding and tomography techniques allowed the determination of the characteristics of the rock deposit, namely the electrical signature (between 19,259 Ωm and 86,316 Ωm), the extension (N90°), the rooting (between 0 and 45 m) and the fracturing (between N14° and N160°) of the granitic formation sought. The modeling resulted in an estimated mineable rock volume of 2,936,250 m<sup>3</sup> providing a production quantity of 7,927,875 tonnes.展开更多
文摘The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to function without disease,whereas dysbiosis has long-standing evidence of etiopathological conditions.The most common communication paths are the microbial release of metabolites,soluble neurotransmitters,and immune cells.However,each pathway is intertwined with a complex one.With the emergence of in vitro models and the popularity of three-dimensional(3D)cultures and Transwells,engineering has become easier for the scientific understanding of neurodegenerative diseases.This paper briefly retraces the possible communication pathways between the gut microbiome and the brain.It further elaborates on three major diseases:autism spectrum disorder,Parkinson’s disease,and Alzheimer’s disease,which are prevalent in children and the elderly.These diseases also decrease patients’quality of life.Hence,understanding them more deeply with respect to current advances in in vitro modeling is crucial for understanding the diseases.Remodeling of MGBA in the laboratory uses many molecular technologies and biomaterial advances.Spheroids and organoids provide a more realistic picture of the cell and tissue structure than monolayers.Combining them with the Transwell system offers the advantage of compartmentalizing the two systems(apical and basal)while allowing physical and chemical cues between them.Cutting-edge technologies,such as bioprinting and microfluidic chips,might be the future of in vitro modeling,as they provide dynamicity.
基金the National Natural Science Foundation of China(Nos.62272063,62072056 and 61902041)the Natural Science Foundation of Hunan Province(Nos.2022JJ30617 and 2020JJ2029)+4 种基金Open Research Fund of Key Lab of Broadband Wireless Communication and Sensor Network Technology,Nanjing University of Posts and Telecommunications(No.JZNY202102)the Traffic Science and Technology Project of Hunan Province,China(No.202042)Hunan Provincial Key Research and Development Program(No.2022GK2019)this work was funded by the Researchers Supporting Project Number(RSPD2023R681)King Saud University,Riyadh,Saudi Arabia.
文摘Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transportationsystem. The movement of vehicles and the three-dimensional (3D) nature of the road network cause the topologicalstructure of IoV to have the high space and time complexity.Network modeling and structure recognition for 3Droads can benefit the description of topological changes for IoV. This paper proposes a 3Dgeneral roadmodel basedon discrete points of roads obtained from GIS. First, the constraints imposed by 3D roads on moving vehicles areanalyzed. Then the effects of road curvature radius (Ra), longitudinal slope (Slo), and length (Len) on speed andacceleration are studied. Finally, a general 3D road network model based on road section features is established.This paper also presents intersection and road section recognition methods based on the structural features ofthe 3D road network model and the road features. Real GIS data from a specific region of Beijing is adopted tocreate the simulation scenario, and the simulation results validate the general 3D road network model and therecognitionmethod. Therefore, thiswork makes contributions to the field of intelligent transportation by providinga comprehensive approach tomodeling the 3Droad network and its topological changes in achieving efficient trafficflowand improved road safety.
文摘Facial wound segmentation plays a crucial role in preoperative planning and optimizing patient outcomes in various medical applications.In this paper,we propose an efficient approach for automating 3D facial wound segmentation using a two-stream graph convolutional network.Our method leverages the Cir3D-FaIR dataset and addresses the challenge of data imbalance through extensive experimentation with different loss functions.To achieve accurate segmentation,we conducted thorough experiments and selected a high-performing model from the trainedmodels.The selectedmodel demonstrates exceptional segmentation performance for complex 3D facial wounds.Furthermore,based on the segmentation model,we propose an improved approach for extracting 3D facial wound fillers and compare it to the results of the previous study.Our method achieved a remarkable accuracy of 0.9999993% on the test suite,surpassing the performance of the previous method.From this result,we use 3D printing technology to illustrate the shape of the wound filling.The outcomes of this study have significant implications for physicians involved in preoperative planning and intervention design.By automating facial wound segmentation and improving the accuracy ofwound-filling extraction,our approach can assist in carefully assessing and optimizing interventions,leading to enhanced patient outcomes.Additionally,it contributes to advancing facial reconstruction techniques by utilizing machine learning and 3D bioprinting for printing skin tissue implants.Our source code is available at https://github.com/SIMOGroup/WoundFilling3D.
文摘Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Our review traces the evolution of CNN, emphasizing the adaptation and capabilities of the U-Net 3D model in automating seismic fault delineation with unprecedented accuracy. We find: 1) The transition from basic neural networks to sophisticated CNN has enabled remarkable advancements in image recognition, which are directly applicable to analyzing seismic data. The U-Net 3D model, with its innovative architecture, exemplifies this progress by providing a method for detailed and accurate fault detection with reduced manual interpretation bias. 2) The U-Net 3D model has demonstrated its superiority over traditional fault identification methods in several key areas: it has enhanced interpretation accuracy, increased operational efficiency, and reduced the subjectivity of manual methods. 3) Despite these achievements, challenges such as the need for effective data preprocessing, acquisition of high-quality annotated datasets, and achieving model generalization across different geological conditions remain. Future research should therefore focus on developing more complex network architectures and innovative training strategies to refine fault identification performance further. Our findings confirm the transformative potential of deep learning, particularly CNN like the U-Net 3D model, in geosciences, advocating for its broader integration to revolutionize geological exploration and seismic analysis.
文摘Building model data organization is often programmed to solve a specific problem,resulting in the inability to organize indoor and outdoor 3D scenes in an integrated manner.In this paper,existing building spatial data models are studied,and the characteristics of building information modeling standards(IFC),city geographic modeling language(CityGML),indoor modeling language(IndoorGML),and other models are compared and analyzed.CityGML and IndoorGML models face challenges in satisfying diverse application scenarios and requirements due to limitations in their expression capabilities.It is proposed to combine the semantic information of the model objects to effectively partition and organize the indoor and outdoor spatial 3D model data and to construct the indoor and outdoor data organization mechanism of“chunk-layer-subobject-entrances-area-detail object.”This method is verified by proposing a 3D data organization method for indoor and outdoor space and constructing a 3D visualization system based on it.
基金his research was funded by Hanoi university of Mining and Geology,Grant Number T22-47.
文摘Mining industrial areas with anthropogenic engineering structures are one of the most distinctive features of the real world.3D models of the real world have been increasingly popular with numerous applications,such as digital twins and smart factory management.In this study,3D models of mining engineering structures were built based on the CityGML standard.For collecting spatial data,the two most popular geospatial technologies,namely UAV-SfM and TLS were employed.The accuracy of the UAV survey was at the centimeter level,and it satisfied the absolute positional accuracy requirement of creat-ing all levels of detail(LoD)according to the CityGML standard.Therefore,the UAV-SfM point cloud dataset was used to build LoD 2 models.In addition,the comparison between the UAV-SfM and TLS sub-clouds of facades and roofs indicates that the UAV-SfM and TLS point clouds of these objects are highly consistent,therefore,point clouds with a higher level of detail and accuracy provided by the integration of UAV-SfM and TLS were used to build LoD 3 models.The resulting 3D CityGML models include 39 buildings at LoD 2,and two mine shafts with hoistrooms,headframes,and sheave wheels at LoD3.
文摘Background With the rapid development of Web3D technologies, the online Web3D visualization, particularly for complex models or scenes, has been in a great demand. Owing to the major conflict between the Web3D system load and resource consumption in the processing of these huge models, the huge 3D model lightweighting methods for online Web3D visualization are reviewed in this paper. Methods By observing the geometry redundancy introduced by man-made operations in the modeling procedure, several categories of light-weighting related work that aim at reducing the amount of data and resource consumption are elaborated for Web3D visualization. Results By comparing perspectives, the characteristics of each method are summarized, and among the reviewed methods, the geometric redundancy removal that achieves the lightweight goal by detecting and removing the repeated components is an appropriate method for current online Web3D visualization. Meanwhile, the learning algorithm, still in improvement period at present, is our expected future research topic. Conclusions Various aspects should be considered in an efficient lightweight method for online Web3D visualization, such as characteristics of original data, combination or extension of existing methods, scheduling strategy, cache man-agement, and rendering mechanism. Meanwhile, innovation methods, particularly the learning algorithm, are worth exploring.
基金the financial support of the National Natural Science Foundation of China(Grant No.52179118)the Graduate Innovation Program of China University of Mining and Technology(Grant No.2022WLKXJ032)the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX22_2581).
文摘The mechanical characteristics of crystalline rocks are affected by the heterogeneity of the spatial distribution of minerals.In this paper,a novel three-dimensional(3D)grain-based model(GBM)based on particle flow code(PFC),i.e.PFC3D-GBM,is proposed.This model can accomplish the grouping of mineral grains at the 3D scale and then filling them.Then,the effect of the position distribution,geometric size,and volume composite of mineral grains on the cracking behaviour and macroscopic properties of granite are examined by conducting Brazilian splitting tests.The numerical results show that when an external load is applied to a sample,force chains will form around each contact,and the orientation distribution of the force chains is uniform,which is independent of the external load level.Furthermore,the number of high-strength force chains is proportional to the external load level,and the main orientation distribution is consistent with the external loading direction.The main orientation of the cracks is vertical to that of the high-strength force chains.The geometric size of the mineral grains controls the mechanical behaviours.As the average grain size increases,the number of transgranular contacts with higher bonding strength in the region connecting both loading points increases.The number of high-strength force chains increases,leading to an increase in the stress concentration value required for the macroscopic failure of the sample.Due to the highest bonding strength,the generation of transgranular cracks in quartz requires a higher concentrated stress value.With increasing volume composition of quartz,the number of transgranular cracks in quartz distributed in the region connecting both loading points increases,which requires many high-strength force chains.The load level rises,leading to an increase in the tensile strength of the numerical sample.
文摘BACKGROUND Duodenum-preserving pancreatic head resection(DPPHR)is the choice of surgery for benign or low-grade malignant tumors of the pancreatic head.Laparoscopic DPPHR(LDPPHR)procedure can be improved by preoperative 3D model reconstruction and the use of intravenous indocyanine green fluorescent before surgery for real-time navigation with fluorescent display to guide the surgical dissection and prevention of from injury to vessels and biliary tract.CASE SUMMARY Here we report the successful short-and long-term outcomes after one year following LDPPHR for a 60-year lady who had an uneventful recovery and was discharged home one week after the surgery.CONCLUSION There was no bile leakage or pancreatic leakage or delayed gastric emptying.The histopathology report showed multiple cysts in the pancreatic head and localized pancreatic intraepithelial tumor lesions.The resected margin was free of tumor.
基金provided by the Talent Training Project of the National Natural Science Foundation of China (No.J0730534)the National Natural Science Foundation of China (No.40902093)+1 种基金the Morning Light Plan of the Shanghai Educational Development Foundation (No.2007CG34)the Open Foundation of the Shanghai Key Laboratory of Urbanization and Ecological Restoration (No.200803)
文摘Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error detection and dynamic correction in 3D geological structure models,we have reviewed the current situation and development trends in 3D geological modeling.The main context of uncertainty in 3D geological structure models is discussed.Major research issues and a general framework system of uncertainty in 3D geological structure models are proposed.We have described in detail the integration of development practices of 3D geological modeling systems,as well as the implementation process for uncertainty evaluation in 3D geological structure models.This study has laid the basis to build theoretical and methodological systems for accuracy assessment and error correction in 3D geological models and can assist in improving 3D modeling techniques under complex geological conditions.
基金supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(Grant No.2023R1 A2C1004298)a grant from the Human Resources Development program(Grant No.20204010600250)of the Korea Institute of Energy Technology Evaluation and Planning(KETEP),funded by the Ministry of Trade,Industry,and Energy of the Korean Government.
文摘To improve the accuracy of indirect tensile strength for a transversely isotropic rock in the Brazilian test, this study considered the three-dimensional (3D) deformation and the nonlinear stress–strain relationship. A parametric study of a numerical Brazilian test was performed for a general range of elastic constants, revealing that the 3D modeling evaluated the indirect tensile strength up to 40% higher than the plane stress modeling. For the actual Asan gneiss, the 3D model evaluated the indirect tensile strength up to 10% higher and slightly enhanced the accuracy of deformation estimation compared with the plane stress model. The nonlinearity in stress–strain curve of Asan gneiss under uniaxial compression was then considered, such that the evaluated indirect tensile strength was affected by up to 10% and its anisotropy agreed well with the physical intuition. The estimation of deformation was significantly enhanced. The further validation on the nonlinear model is expected as future research.
文摘To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D modeling to DTs modeling is analyzed,as well as the current application of DTs modeling in various industries.The application of 3D DTs modeling in theelds of smartmanufacturing,smart ecology,smart transportation,and smart buildings in smart cities is analyzed in detail,and the current limitations are summarized.It is found that the 3D modeling technology in DTs has broad prospects for development and has a huge impact on all walks of life and even human lifestyles.At the same time,the development of DTs modeling relies on the development and support capabilities of mature technologies such as Big Data,Internet of Things,Cloud Computing,Articial Intelligence,and game technology.Therefore,although some results have been achieved,there are still limitations.This work aims to provide a good theoretical support for the further development of 3D DTs modeling.
基金financially supported by the Scientific Research Startup Foundation of Xinjiang University(No.620312377)the National Science and Technology Major Project of China(No.2016ZX05053-013)
文摘The formation heterogeneity is considered as one of the major factors limiting the application of foam flooding.In this paper,influences of formation properties,such as permeability,permeability distribution,interlayer,sedimentary rhythm and 3D heterogeneity,on the mobility control capability and oil displacement efficiency of foam flooding,were systematically investigated using 2D homogeneous and 2D/3D heterogeneous models under 120°C and salinity of 20×10~4 mg/L.The flow resistance of foam was promoted as the permeability increased,which thus resulted in a considerable oil recovery behavior.In the scenario of the vertical heterogeneous formations,it was observed that the permeability of the high-permeable layer was crucial to foam mobility control,and the positive rhythm appeared favorable to improve the foam flooding performance.The additional oil recovery increased to about 40%.The interlayer was favorable for the increases in mobility reduction factor and oil recovery of foam flooding when the low permeability ratio was involved.For the 3D heterogeneous formations,foam could efficiently adjust the areal and vertical heterogeneity through mobility control and gravity segregation,and thus enhancing the oil recovery to 11%–14%.The results derived from this work may provide some insight for the field test designs of foam flooding.
基金funded by the Ministry of Science and Higher Education of the Russian Federation as part of the World-Class Research Center Program:Advanced Digital Technologies(Contract No.075-15-2022-311,dated 20.04.2022).
文摘Background:Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment outcomes.The introduction of this technique into pediatric cardiac surgery will allow us to study features of the anatomy and spatial relations of a defect and to simulate the optimal surgical repair on a printed model in every individual case.Methods:We performed the prospective cohort study which included 29 children with congenital heart defects.The hearts and the great vessels were modeled and printed out.Measurements of the same cardiac areas were taken in the same planes and points at multislice computed tomography images(group 1)and on printed 3D models of the hearts(group 2).Pre-printing treatment of the multislice computed tomography data and 3D model preparation were performed according to a newly developed algorithm.Results:The measurements taken on the 3D-printed cardiac models and the tomographic images did not differ significantly,which allowed us to conclude that the models were highly accurate and informative.The new algorithm greatly simplifies and speeds up the preparation of a 3D model for printing,while maintaining high accuracy and level of detail.Conclusions:The 3D-printed models provide an accurate preoperative assessment of the anatomy of a defect in each case.The new algorithm has several important advantages over other available programs.They enable the development of customized preliminary plans for surgical repair of each specific complex congenital heart disease,predict possible issues,determine the optimal surgical tactics,and significantly improve surgical outcomes.
基金supported by the National Natural Science Foundation of China (42172333,41902304,U1711267)the fund of the State Key Laboratory of Biogeology and Environmental Geology (2021)+1 种基金Science and Technology Strategic Prospecting Project of Guizhou Province ( [2022]ZD003)the Knowledge Innovation Program of Wuhan-Shuguang Project (2022010801020206).
文摘Nowadays,Web browsers have become an important carrier of 3D model visualization because of their convenience and portability.During the process of large-scale 3D model visualization based on Web scenes with the problems of slow rendering speed and low FPS(Frames Per Second),occlusion culling,as an important method for rendering optimization,can remove most of the occluded objects and improve rendering efficiency.The traditional occlusion culling algorithm(TOCA)is calculated by traversing all objects in the scene,which involves a large amount of repeated calculation and time consumption.To advance the rendering process and enhance rendering efficiency,this paper proposes an occlusion culling with three different optimization methods based on the WebGPU Computing Pipeline.Firstly,for the problem of large amounts of repeated calculation processes in TOCA,these units are moved from the CPU to the GPU for parallel computing,thereby accelerating the calculation of the Potential Visible Sets(PVS);Then,for the huge overhead of creating pipeline caused by too many 3D models in a certain scene,the Breaking Occlusion Culling Algorithm(BOCA)is introduced,which removes some nodes according to building a Hierarchical Bounding Volume(BVH)scene tree to reduce the overhead of creating pipelines;After that,the structure of the scene tree is transmitted to the GPU in the order of depth-first traversal and finally,the PVS is obtained by parallel computing.In the experiments,3D geological models with five different scales from 1:5,000 to 1:500,000 are used for testing.The results show that the proposed methods can reduce the time overhead of repeated calculation caused by the computing pipeline creation and scene tree recursive traversal in the occlusion culling algorithm effectively,with 97%rendering efficiency improvement compared with BOCA,thereby accelerating the rendering process on Web browsers.
基金supported by the National Natural Science Foundation of China (Grant No.42171311)the Open Fund of State Key Laboratory of Remote Sensing Science (Grant No.OFSLRSS202218)+1 种基金the Key Research and Development Program of the Hainan Province,China (Grant No.ZDYF2021SHFZ105)the Training Program of Excellent Master Thesis of Zhejiang Ocean University.
文摘The acquisition of digital regional-scale information and ecological environmental data has high requirements for structural texture,spatial res-olution,and multiple parameter categories,which is challenging to achieve using satellite remote sensing.Considering the convenient,facilitative,and flexible characteristics of UAV(unmanned air vehicle)remote sensing tech-nology,this study selects a campus as a typical research area and uses the Pegasus D2000 equipped with a D-MSPC2000 multi-spectral camera and a CAM3000 aerial camera to acquire oblique images and multi-spectral data.Using professional software,including Context Capture,ENVI,and ArcGIS,a 3D(three-dimensional)campus model,a digital orthophoto map,and multi-spectral remote sensing map drawing are realized,and the geometric accuracy of typical feature selection is evaluated.Based on a quantitative remote sensing model,the campus ecological environment assessment is performed from the perspectives of vegetation and water body.The results presented in this study could be of great significance to the scientific management and sustainable development of regional natural resources.
基金This work was supported by China Postdoctoral Science Foundation(No.2022M723391)the Science and Technology Innovation Project of Higher Education in Shanxi Province(No.2019L0754)+1 种基金the Central Guiding Local Science and Technology Development Fund Project(No.YDZJSX2021B021)Shanxi Province Basic Research Plan General Project(No.202203021221294).
文摘This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of complex frequency-shifted perfectly matched layer(CFS-PML)was used for truncation so that the low-frequency electromagnetic wave can be better absorbed at the model boundary.A typical three-dimensional(3D)homogeneous half-space model was established and a low-resistivity cube model was analyzed under the half-space condition.The response patterns and drivers of the low-resistivity cube model were discussed under the influence of a low-resistivity overburden.The absorption boundary conditions of CFS-PML significantly affected the low-frequency electromagnetic waves.For a low-resistivity cube around the borehole,its response curve exhibited a single-peak,and the extreme point of the curve corresponded to the center of the low-resistivity body.When the low-resistivity cube was directly below the borehole,the response curve showed three extreme values(two high and one low),with the low corresponding to the center of the low-resistivity body.The total field response of the low-resistivity overburden was stronger than that of the uniform half-space model due to the low-resistivity shielding effect of electromagnetic waves.When the receiving-transmitting distance gradually increased,the effect of the low-resistivity overburden was gradually weakened,and the response of the low-resistivity cube was strengthened.It was affected by the ratio of the overburden resistivity to the resistivity of the low-resistivity body.
文摘A grain-based distinct element model featuring three-dimensional (3D) Voronoi tessellations (randompoly-crystals) is proposed for simulation of crack damage development in brittle rocks. The grainboundaries in poly-crystal structure produced by Voronoi tessellations can represent flaws in intact rockand allow for numerical replication of crack damage progression through initiation and propagation ofmicro-fractures along grain boundaries. The Voronoi modelling scheme has been used widely in the pastfor brittle fracture simulation of rock materials. However the difficulty of generating 3D Voronoi modelshas limited its application to two-dimensional (2D) codes. The proposed approach is implemented inNeper, an open-source engine for generation of 3D Voronoi grains, to generate block geometry files thatcan be read directly into 3DEC. A series of Unconfined Compressive Strength (UCS) tests are simulated in3DEC to verify the proposed methodology for 3D simulation of brittle fractures and to investigate therelationship between each micro-parameter and the model's macro-response. The possibility of numericalreplication of the classical U-shape strength curve for anisotropic rocks is also investigated innumerical UCS tests by using complex-shaped (elongated) grains that are cemented to one another alongtheir adjoining sides. A micro-parameter calibration procedure is established for 3D Voronoi models foraccurate replication of the mechanical behaviour of isotropic and anisotropic (containing a fabric) rocks. 2014 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.
文摘This study proposes a detailed concept of how landscape changes can be transferred and communicated in a 3D environment using the storytelling approach. In 2018, Mocnik and Fairbairn argued that maps are good for representing a geographic space but texts have a better benefit than maps for telling a story [1]. A framework is presented on how a landscape change can be retrieved out of textual descriptions. A prototype of a 3D model with a projection on top of it was developed. The case study tells the story of the landscape change in the city of Pristina. The key element of the visualization is a timeline. Several media like cadastral maps, orthophotos, texts, graphics, and background sound are used and combined in an animated light show and the visualization was evaluated within a user study.
文摘A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite based on the electrical resistivity methods. The combination of electrical trailing, sounding and tomography techniques allowed the determination of the characteristics of the rock deposit, namely the electrical signature (between 19,259 Ωm and 86,316 Ωm), the extension (N90°), the rooting (between 0 and 45 m) and the fracturing (between N14° and N160°) of the granitic formation sought. The modeling resulted in an estimated mineable rock volume of 2,936,250 m<sup>3</sup> providing a production quantity of 7,927,875 tonnes.