3-D Animation as Applied to the Solving of Coupling Relations in the 6-DOF Parallel Robot

How to solve the coupling relations in a 6 - DOF parallel robot quickly and accurately within the limits of realtime control is a critical problem. In traditional analytic method, the complicated mathemtical model must first be constructed and then solved by programming.Obviously, this method is not very practical. This paper,therefore, proposes a new way of approach with a new method using 3- D animation for the solving of coupling relations in the 6 - DOF parallel robot. This method is much simpler and its solving accuracy approaches that of the more complicated analytic method.

Development and Evaluation of 3D Delivery Animation Software Designed to Improve the Mother’s and Spouse’s Satisfaction with Delivery

Purpose: To clarify the effectiveness of 3-D delivery animation software for the mother’s and husband’s satisfaction with delivery. Subjects and Method: We independently developed a software application used to display the pelvic region and explain the labor process. The study involved a collaboration with hospital staff who recruited 18 primiparous and 18 multiparous mothers who were hospitalized for delivery at Facility A. The midwife explained the process of delivery using the “Delivery Animation Software”. A self-administered, anonymous questionnaire was distributed and analyzed separately for primiparous and multiparous mothers and their husbands. Results: 1) For both primiparous and multiparous couples, both mothers and their husbands gained a significantly higher level of understanding after delivery than during pregnancy. 2) The Self-Evaluation Scale for Experience of Delivery results were as follows: “I did my best for the baby even if it was painful” was selected more often for “birth coping skills”;“reliable medical staff” was selected more often for “physiological birth process”;“the birth progressed as I expected” was selected frequently by primiparous mothers;and “the birth progressed smoothly” was selected often by multiparous mothers. 3) In terms of husbands’ satisfaction with the delivery, “I was satisfied with the delivery”, “I was given an easy-to-understand explanation”, and “They explained the process to me” was selected of primiparous and multiparous fathers. 4) All primiparous and multiparous mothers positively evaluated whether the delivery animation was helpful in understanding the process of delivery. Conclusion: The delivery animation was effective in improving the understanding and satisfaction of both the mothers and their husbands.

(1-3)-β-D葡聚糖联合降钙素原、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究

目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将其分为马尔尼菲篮状菌感染确诊组(血或组织液培育养出马尔尼菲篮状菌),简称A组(62例),及马尔尼菲篮状菌感染临床诊断组[根据临床症状、体征、血常规及(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞多指标诊断],简称B组(58例)。检测患者(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞的表达水平,采用受试者工作特征(receiver-operating characteristic,ROC)曲线下面积(area under the curve,AUC)评估上述指标联合检测对艾滋病患者感染马尔尼菲篮状菌的诊断效能。结果A组的(1-3)-β-D葡聚糖和PCT水平均高于B组,CD4^(+)T淋巴细胞个数低于B组(P<0.05);(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞联合检测的AUC为0.933,(1-3)-β-D葡聚糖单独检测的AUC是0.812,PCT单独检测的AUC为0.883,CD4^(+)T淋巴细胞单独检测的AUC是0.810,(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的AUC皆优于三项单独检测,表明(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的诊断价值皆优于单一指标诊断,且联合检测的特异度、约登指数分别为92.43%和0.580,均高于三项单独检测。结论(1-3)-β-D葡聚糖联合PCT和CD4^(+)T淋巴细胞多指标对艾滋病马尔尼菲篮状菌感染具有非常高的临床诊断价值,能够帮助医生分析出高危风险患者,及时制定治疗方案,同时也承担预后效果的判断依据,对治疗艾滋病马尔尼菲篮状菌感染具有非常重要的研究价值。

血浆(1-3)-β-D葡聚糖诊断新生儿侵袭性真菌感染的价值

探讨在针对新生儿侵袭性真菌感染的诊断中使用血浆(1-3)-β-D葡聚糖能够产生的诊断效能。方法 选取2021年1月到2022年2月因为侵袭性真菌感染于医院寻求医疗干预的新生儿总共60例作为本次研究的一部分研究对象记为1组;另外选取60例健康婴儿作为2组;统计、对比两组患者的血浆(1-3)-β-D葡聚糖水平、CD4+T淋巴细胞数水平;整理PCR技术针对1组患者诊断结果,将其与血浆(1-3)-β-D葡聚糖诊断侵袭性真菌感染的诊断效能进行对比。结果 研究结果显示1组患者的血浆(1-3)-β-D葡聚糖水平、CD4+T淋巴细胞数水平较之于2组患者存在明显差异,1组患者血浆(1-3)-β-D葡聚糖水平更高,而CD4+T淋巴细胞数水平明显更低;P<0.05。在针对诊断效能的考察上,血浆(1-3)-β-D葡聚糖诊断效能和PCR诊断结果之间在灵敏度、特异度方面差异不大,P>0.05。结论 针对罹患侵袭性真菌感染的新生儿使用血浆(1-3)-β-D葡聚糖进行检查,一定程度上能够确保诊断结果的严谨程度,可使用。

Research on the Application of Virtual Simulation and 3D Animation Technology in the Teaching of Road and Bridge Majors in Higher Vocational Colleges

The informatization of higher vocational education is the future development trend,and it is also encouraged and promoted by the Ministry of Education.This article focuses on the road and bridge major,combined with the author’s experience in introducing virtual simulation and three-dimensional(3D)animation technology into relevant course teaching in recent years,discusses the application of virtual simulation and 3D animation technology in higher vocational education and promotes classroom revolution,to obtain better teaching effect.

miR-421靶向调控Menin/Caspase-3影响抑郁症的机制

目的探讨miR-421影响抑郁症发生发展的作用机制。方法采取单次腹腔注射脂多糖(LPS)方法建立抑郁大鼠模型,采用糖水偏好度测试和旷场实验进行抑郁行为检测。通过miRNA微阵列芯片和RT-PCR分析miR-421在抑郁大鼠海马组织中的表达量,运用TargetScan数据库和mi RDB数据库进行预测miR-421的靶基因,采用双荧光素酶报告基因实验观察其与靶基因的结合情况,观察过表达和抑制miR-421对靶基因的影响,随后过表达和抑制靶基因,观察其对下游因子的影响,最终探究miR-421影响抑郁症的相关机制。结果miRNA微阵列芯片和RT-PCR检测表明miR-421在抑郁大鼠海马组织中呈高表达(P<0.001),抑制miR-421的表达可显著恢复抑郁大鼠的体重和运动能力(P<0.001)。TargetScan数据库预测得到Menin与miR-421存在结合靶点,双荧光素酶报告基因实验表明Menin与miR-421具有相互作用;当miR-421过表达时,Menin表达量会下调(P<0.001),相反,当抑制miR-421表达时,Menin表达量会上调(P<0.001)。qPCR检测提示,Menin下游因子Caspase-3、NF-κB在抑郁大鼠模型海马组织中的表达显著提高(P<0.001),IL-1β在抑郁大鼠模型海马组织中的表达明显提高(P<0.01),当抑制Menin表达时,Caspase-3、NF-κB、IL-1β表达量会升高(P<0.001),当过表达Menin时,Caspase-3、NF-κB、IL-1β表达量则降低(P<0.001)。结论抑制miR-421表达可升高Menin表达,降低Caspase-3含量,减少神经炎症反应,从而改善抑郁症状。

Parallel computing approach for efficient 3-D X-ray-simulated image reconstruction

Accurate 3-dimensional(3-D)reconstruction technology for nondestructive testing based on digital radiography(DR)is of great importance for alleviating the drawbacks of the existing computed tomography(CT)-based method.The commonly used Monte Carlo simulation method ensures well-performing imaging results for DR.However,for 3-D reconstruction,it is limited by its high time consumption.To solve this problem,this study proposes a parallel computing method to accelerate Monte Carlo simulation for projection images with a parallel interface and a specific DR application.The images are utilized for 3-D reconstruction of the test model.We verify the accuracy of parallel computing for DR and evaluate the performance of two parallel computing modes-multithreaded applications(G4-MT)and message-passing interfaces(G4-MPI)-by assessing parallel speedup and efficiency.This study explores the scalability of the hybrid G4-MPI and G4-MT modes.The results show that the two parallel computing modes can significantly reduce the Monte Carlo simulation time because the parallel speedup increment of Monte Carlo simulations can be considered linear growth,and the parallel efficiency is maintained at a high level.The hybrid mode has strong scalability,as the overall run time of the 180 simulations using 320 threads is 15.35 h with 10 billion particles emitted,and the parallel speedup can be up to 151.36.The 3-D reconstruction of the model is achieved based on the filtered back projection(FBP)algorithm using 180 projection images obtained with the hybrid G4-MPI and G4-MT.The quality of the reconstructed sliced images is satisfactory because the images can reflect the internal structure of the test model.This method is applied to a complex model,and the quality of the reconstructed images is evaluated.

血清25-羟维生素-D3 超敏C反应蛋白及心电图参数与ST段抬高型心肌梗死患者介入治疗后发生恶性心律失常的关系

目的:探讨血清25-羟维生素-D3(25-hydroxyvitamin D3,25-(OH)-D3)、超敏C反应蛋白(High sensitivity C-reactive protein,hs-CRP)、心电图参数变化与ST段抬高型心肌梗死(ST segment elevation myocardial infarction,STEMI)患者经皮冠脉介入术(Percutaneous coronary intervention,PCI)后发生恶性心律失常的关系。方法:选取我院2020年1月至2022年6月实施PCI治疗的193例STEMI患者作为研究对象,根据患者术后72h内是否发生恶性心律失常分为心律失常组38例、对照组155例,对比两组患者入院12h内的25-(OH)-D3、hs-CRP、血清电解质、血常规指标、血脂指标、心肌酶学指标,并对患者PCI术后实施连续动态心电图监测,对比两组患者心电图碎裂QRS波、校正Tp-e间期(Corrected Tp-e interval,Tp-ec)、QT离散度(QT dispersion,Qtd),并采用Logistic回归模型分析上述指标与STEMI患者PCI术后发生恶性心律失常的关系。结果:心律失常组患者的血清25-(OH)-D3水平低于对照组,心律失常组患者的血清hs-CRP、Tp-ec测定值、Qtd测定值、碎裂QRS波检出率均高于对照组,上述指标组间差异均具有统计学意义(P<0.05);心律失常组患者的白细胞(White blood cell,WBC)、肌钙蛋白I(Troponin I,cTnI)、肌酸激酶同工酶(Creatine kinase isoenzyme,CK-MB)、肌红蛋白(Myoglobin,MYO)、K+、Mg 2+水平均高于对照组患者,差异具有统计学意义(P<0.05);Logistic回归模型结果显示:cTnI、CK-MB、K+、hs-CRP、Tp-ec、Qtd增高,碎裂QRS波阳性会显著增大STEMI患者PCI后发生恶性心律失常的风险(P<0.05);血清25-(OH)-D3水平增高会降低STEMI患者PCI后发生恶性心律失常的风险(P<0.05)。结论:STEMI患者血清25-(OH)-D3水平降低、hs-CRP增高、PCI术后Tp-ec、Qtd增高、出现碎裂QRS波会增大患者出现恶性心律失常的风险。

Building 3-D Human Data Based on Handed Measurement and CNN

3-dimension(3-D)printing technology is growing strongly with many applications,one of which is the garment industry.The application of human body models to the garment industry is necessary to respond to the increasing personalization demand and still guarantee aesthetics.This paper proposes amethod to construct 3-D human models by applying deep learning.We calculate the location of the main slices of the human body,including the neck,chest,belly,buttocks,and the rings of the extremities,using pre-existing information.Then,on the positioning frame,we find the key points(fixed and unaltered)of these key slices and update these points tomatch the current parameters.To add points to a star slice,we use a deep learning model tomimic the form of the human body at that slice position.We use interpolation to produce sub-slices of different body sections based on the main slices to create complete body parts morphologically.We combine all slices to construct a full 3-D representation of the human body.

Conical Sonic-Supersonic Solutions for the 3-D Steady Full Euler Equations

This paper concerns the sonic-supersonic structures of the transonic crossflow generated by the steady supersonic flow past an infinite cone of arbitrary cross section.Under the conical assumption,the three-dimensional(3-D)steady Euler equations can be projected onto the unit sphere and the state of fluid can be characterized by the polar and azimuthal angles.Given a segment smooth curve as a conical-sonic line in the polar-azimuthal angle plane,we construct a classical conical-supersonic solution near the curve under some reasonable assumptions.To overcome the difficulty caused by the parabolic degeneracy,we apply the characteristic decomposition technique to transform the Euler equations into a new degenerate hyperbolic system in a partial hodograph plane.The singular terms are isolated from the highly nonlinear complicated system and then can be handled successfully.We establish a smooth local solution to the new system in a suitable weighted metric space and then express the solution in terms of the original variables.

Adaptive Window Based 3-D Feature Selection for Multispectral Image Classification Using Firefly Algorithm

Feature extraction is the most critical step in classification of multispectral image.The classification accuracy is mainly influenced by the feature sets that are selected to classify the image.In the past,handcrafted feature sets are used which are not adaptive for different image domains.To overcome this,an evolu-tionary learning method is developed to automatically learn the spatial-spectral features for classification.A modified Firefly Algorithm(FA)which achieves maximum classification accuracy with reduced size of feature set is proposed to gain the interest of feature selection for this purpose.For extracting the most effi-cient features from the data set,we have used 3-D discrete wavelet transform which decompose the multispectral image in all three dimensions.For selecting spatial and spectral features we have studied three different approaches namely overlapping window(OW-3DFS),non-overlapping window(NW-3DFS)adaptive window cube(AW-3DFS)and Pixel based technique.Fivefold Multiclass Support Vector Machine(MSVM)is used for classification purpose.Experiments con-ducted on Madurai LISS IV multispectral image exploited that the adaptive win-dow approach is used to increase the classification accuracy.

Fe_(3)O_(4)/BiOBr/BiOI的制备及降解2,4-D的性能研究

采用水热法制备了微米球花状结构的Fe_(3)O_(4)/BiOBr/BiOI复合材料,通过SEM、XRD、XPS和UV-Vis等手段对催化剂进行表征分析。结果表明,该催化剂对2,4-D具有高效的光降解性能和光催化效率(80 min,88%)。降解速率常数为2.498×10^(-2)min^(-1),分别是Br∶I=5∶5(K=2.004×10^(-2)min^(-1))、BiOBr(K=1.289×10^(-2)min^(-1))和BiOI(K=6.98×10-3min-1)的1.25倍、1.94倍与3.58倍。这是由于Fe_(3)O_(4)/BiOBr/BiOI复合材料内部形成了异质结,利于光生载流子的分离。此外,5次循环实验后,降解效率保持在82.9%,证明该催化剂稳定、可回收、可磁分离。

水产动物维生素D_(3)需求、吸收和转运及其与糖脂代谢的关系

维生素D_(3)是水产养殖动物必需的微量营养素,在维持水产动物正常生长、发育和营养代谢等方面具有重要功能。水产动物几乎不能合成维生素D_(3),主要通过食物获取。为了深入解析维生素D_(3)调控水产动物糖脂代谢的机制,本文综述了近12年来最新的研究进展,包括水产动物对饲料维生素D_(3)需求量及其影响因素、维生素D_(3)吸收、转运和代谢机理,以及维生素D_(3)调控糖脂代谢的机制。已有的研究主要聚焦于水产动物维生素D_(3)营养生理、代谢和对糖脂代谢的调控,但仍有很多重要的科学问题尚未解决。重点需制定统一的水产动物维生素D_(3)需求量评价标准,加强维生素D_(3)对水产动物糖脂代谢及机制的研究,从而为水产动物维生素D_(3)营养的精准调控奠定基础。

A"messenger zone hypothesis"based on the visual three-dimensional spatial distribution of motoneurons innervating deep limb muscles

Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.

3D Product Display Based on Inventor Animation Design

With the rapid development of internet technology,some innovative fashion product are increasingly showed in the way of three-dimensional virtual display.Taking fashion jewelry as an example,the virtual 3D display method of product is studied by Inventor which is parametric 3D design software for efficient modeling and animation developed by the Autodesk Company.By discussing the methods of part feature creation and assembly design,the real simulation of the product is carried out.Three-dimensional animation techniques,such as fade animation,components animation and camera animation are used to depict product features and animation effects.

THE SUMERIAN TERM u_(8)/ud_(5)/ab_(2)/eme_(3)/_(6)sila_(4)/maš_(2)/amar du_(3)(-a)

The aim of the present article is twofold:firstly,to prove that the expression animal+young du_(3)(-a),which is basically documented in texts from the 3rd millennium BC,refers to a dam that has just given birth,and secondly,to show the information concerning female animals and their newborns available in the texts.

胰岛素样生长因子结合蛋白3在脑梗死模型的表达及Smad信号通路的参与机制

目的 探讨Smad信号通路机制在脑梗死模型大鼠中的作用以及脑组织胰岛素样生长因子结合蛋白3(IGFBP-3)的表达变化与神经功能的关系。方法 60只健康成年雄性SD大鼠随机分为模型组、假手术组及正常对照组,每组20只,模型组采用线栓法建立脑梗死模型,假手术组仅暴露颈内动脉后直接缝合皮肤,建模成功后1周评估各组大鼠的改良神经功能缺损(mNSS)评分。采用苏木精-伊红染色法检测脑组织病理学变化情况,采用Western blot法对大鼠脑组织中IGFBP-3、Smad2、Smad4蛋白水平进行检测,并采用逆转录聚合酶链反应测定大鼠脑组织中IGFBP-3、Smad2、Smad4 mRNA水平。用Spearman相关性分析IGFBP-3、Smad2、Smad4、P21表达水平之间的相关性。结果 苏木精-伊红染色结果显示,模型组大鼠出现明显脑组织水肿,表现为脑细胞排列紊乱,小胶质细胞数量变多,脑细胞核仁出现模糊,其中脑梗死面积为20.55%。与假手术组和正常对照组比较,模型组大鼠mNSS评分、IGFBP-3、Smad2、Smad4蛋白及mRNA相对表达水平明显升高,P21蛋白及mRNA相对表达水平明显降低(P<0.05,P<0.01)。Spearman相关性分析显示,模型组大鼠脑组织中IGFBP-3 mRNA表达水平与mNSS评分、Smad2 mRNA、Smad4 mRNA呈显著正相关(r=0.568,r=0.623,r=0.597,P<0.01);IGFBP-3 mRNA表达水平与P21呈显著负相关(r=-0.573,P<0.01)。结论 脑梗死大鼠脑组织IGFBP-3水平显著升高,且IGFBP-3水平与脑梗死大鼠神经功能之间关系密切,其作用机制可能与Smad信号通路有关。

3D Reconstruction and Animation of Brain MRI Images Based on Matlab

The following algorithms are proposed and realized by MATLAB programming based on the brain MRI images:(1)The 3D surface of the brain is reconstructed using MC algorithm.(2)A rotate animation of the brain is created and displayed by 3D rotate transformation and animation functions of Matlab.Result shows that the algorithm can show the brain accurately and quickly,takes up less space in memory.

深部真菌感染患者血浆1-3-β-D葡聚糖检测的临床意义

目的探讨深部真菌感染患者血浆1-3-β-D葡聚糖检测的临床意义。方法 应用ME-80微生物动态快速 检测系统,及GKT-5M Set动态真菌检测试剂盒定量检测血浆中1-3-β-D葡聚糖的含量。结果正常对照组血浆 1-3-β-D葡聚糖含量为(2.83士2.57)μg／L;深部真菌感染组为(54.06士36.13)μg／L,经t检验分析,对照组与深部 真菌感染组1-3-β-D葡聚糖平均值差异非常显著(t=7.741,P<0.001)。结论 血浆葡聚糖检测可在拟诊早期为 临床医生提供机体是否感染真菌的可靠信息,是一种实用的真菌感染早期诊断方法。