Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneuro...Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.展开更多
The distributions of the axial stress and shear stress in Al2O3-TiC/Q235 diffusion bonded joints were studied using finite element method （FEM）. The effect of interlayer thickness on the axial stress and shear stres...The distributions of the axial stress and shear stress in Al2O3-TiC/Q235 diffusion bonded joints were studied using finite element method （FEM）. The effect of interlayer thickness on the axial stress and shear stress was also investigated. The results indicate that the gradients of the axial stress and shear stress are great near the joint edge. The maximal shear stress produces at the interface of the Al2O3-TIC and Ti interlayer. With the increase of Cu interlayer thickness, the magnitudes of the axial stress and shear stress first decrease and then increase. The distribution of the axial stress changes greatly with a little change in the shear stress. The shear fracture initiates at the interface of the Al2O3-TiC/ Ti interlayer with high shear stress and then propagates to the Al2O3-TIC side, which is consistent with the stress FEM calculating results.展开更多
Cucumber seedlings were sprayed with different concentrations of LaCl_3 for 3 d continuously. After 7 d of this treatment, the plants were treated with 1200 mg·L^(-1) 2,4-dichlorophennoxy(2,4-D) for 24 h. The lea...Cucumber seedlings were sprayed with different concentrations of LaCl_3 for 3 d continuously. After 7 d of this treatment, the plants were treated with 1200 mg·L^(-1) 2,4-dichlorophennoxy(2,4-D) for 24 h. The leaves were harvested and rinsed with 5 mmol·L^(-1) EDTA. The concentrations of photosynthetic pigments, soluble protein and metabolites related to oxidative stress and the activities of antioxidant enzymes in leaves were assayed. The results show that the treatment with appropriate concentration of LaCl_3 has resistant effect on oxidative stress induced by 2, 4-D. Proper concentration of LaCl_3 promotes the activity of antioxidant system in plants and alleviates the damage caused by 2, 4-D.展开更多
The time-domain BEM was developed to analyze the dynamic stress intensity factor ( DSIF) of 3-D elastodynamic crack problems. To simulate the stress singularity along the front of a crack, eight-node isoparametric sin...The time-domain BEM was developed to analyze the dynamic stress intensity factor ( DSIF) of 3-D elastodynamic crack problems. To simulate the stress singularity along the front of a crack, eight-node isoparametric singular elements were used, and the DSIF for a semi-circular surface crack was firstly calculated based on displacement equation using the time-domain BEM formulation. The new scheme to determine the time step was brought forward. By the dynamic analysis program of time-domain BEM compiled by its, several numerical examples are presented, which demonstrate the unconditional stability and high accuracy of time-domain BEM applied to 3-D elastodynamic crack problems.展开更多
According to turbulent theory and characteristics of beam blank continuous casting, 3-D model to represent the flow of beam blank mould is established. The predicted results indicate that the exit obliquity of up 15&#...According to turbulent theory and characteristics of beam blank continuous casting, 3-D model to represent the flow of beam blank mould is established. The predicted results indicate that the exit obliquity of up 15°(+15°) should be adopted, which will benefit the floatation of non-metallic inclusion and purification of the molten steel. When the nozzle angle is 120°, the flow pattern is reasonable. Proper nozzle depth can be 200mm. Turbulent kinetic of meniscus can be reduced by adopting the square nozzle and suitable area of side outlet when casting speed increases. The results are consistent with those of water model experiment, so the model is exact and reasonable. The model can provide important information for design of SEN and defining of immersion depth.展开更多
Applying 3-dimension finite difference method, the distribution characteristics of horizontal field transfer functions for rectangular conductor have been computed, and the law of distribution for Re-part and Im-part ...Applying 3-dimension finite difference method, the distribution characteristics of horizontal field transfer functions for rectangular conductor have been computed, and the law of distribution for Re-part and Im-part has been given. The influences of source field period, the conductivity, the buried depth and the length of the conductor on the transfer functions were studied. The extrema of transfer functions appear at the center, the four corners and around the edges of conductor, and move with the edges. This feature demonstrates that around the edges are best places for transfer functions' observation.展开更多
In this study,the interaction between 3-D bedforms and submerged rigid vegetation has been investigated.Various laboratory experiments were conducted to study the distribution of flow velocity,Reynolds shear stress,tu...In this study,the interaction between 3-D bedforms and submerged rigid vegetation has been investigated.Various laboratory experiments were conducted to study the distribution of flow velocity,Reynolds shear stress,turbulent kinetic energy,and skewness coefficients for a constant density of vegetation.Results showed that the velocity profile in the pool section deviates from those in the upstream section of the pool.It has been found that the dip parameter varied between 0.6H and 0.9H depending on various factors including bed roughness,vegetation distribution,and pool entrance/exit slopes.However,scattered vegetation in the pool and differences in slopes created non-uniform flow conditions.Also,in the wake region behind each vegetated element,flow velocity reduced significantly,and small-scale eddies are formed,causing increased perturbations.By decreasing the entrance slope and bed roughness,relatively uniform flow and weaker turbulence was resulted,but the random distribution of vegetated elements counteracted this balance and intensified turbulence.With the decrease in the pool entrance slope,the contribution of sweep event decreased and the contribution of ejection event increased.展开更多
The Shangzhuang altered-rock type gold ore deposit is located in the middle segment of and controlled by the Wang＇ershan fault zone in the northwestern part of the Jiaodong gold province, China. The deformation evolu...The Shangzhuang altered-rock type gold ore deposit is located in the middle segment of and controlled by the Wang＇ershan fault zone in the northwestern part of the Jiaodong gold province, China. The deformation evolution, the structure of strain and stress fields and its ore-controlling effect in the Shangzhuang deposit are discussed in this paper. It is revealed that the deformation evolution has mainly undergone four phases： the early ductile deformation, the second NE-striking horizontal simple shear, the third NE-striking compression-shear and the final NW-striking compression. The mineralization happened during the third stage in which the maximum principal stress gradually transited from NE to NW. The 3-D numerical simulations of the stress field show that, on the condition that the maximum principal stress is NE-striking, the fracture development in the fault zone is favored, while when the maximum principal stress is NW-striking, the fault zone is relatively extensional and it is suitable for the influx and emplacement of ore-forming fluids. The compression-shear strain field during the mineralization is characterized by the λ-type structure, the positive flower structure, etc. Orebodies are mostly equidistantly located in the dilatational spaces, which are distributed in the integral compressional circumstances. And the dilatational spaces are developed where the fault attitude changes or shear joint systems develop. In the overall compression-shear stress field, the strain field bears self-similarity at multiple scales, including the orebody, ore deposit and orefield. The selfsimilarity of the structure comprises the subequidistant distribution of fractures at the same scale and the similar shape of the fractures at various scales. Yet, due to the special geological structure, the orebodies are mostly located in the hanging wall in the Shangzhuang deposit, which is different from most deposits in the Jiaodong gold province. Analyses of the ore-controlling stress and strain fields in the deposit provide an important basis for deposit seeking.展开更多
The Self-Similar Crack Expansion (SSCE) method is used to calculate stress intensity factors for three-dimensional cracks in an infinite medium or semi-infinite medium by the boundary integral element technique, where...The Self-Similar Crack Expansion (SSCE) method is used to calculate stress intensity factors for three-dimensional cracks in an infinite medium or semi-infinite medium by the boundary integral element technique, whereby, the stress intensity factors at crack tips are determined by calculating the crack-opening displacements over the crack surface. For elements on the crack surface, regular integrals and singular integrals are precisely evaluated based on closed form expressions, which improves the accuracy. Examples shaw that this method yields very accurate results for stress intensity factors of penny-shaped cracks and elliptical cracks in the full space, with errors of less than 1% as compared with analytical solutions. The stress intensity factors of subsurface cracks ate in good agreement with other analytical solutions.展开更多
基金supported by the Chinese National General Program of the National Natural Science Foundation of China,No.82072162(to XY)。
文摘Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.
基金supported by National Natural Science Foundation of China (Grant No. 50874069)Development Project of Science and Technology of Shandong Province (2007GG10004016)+1 种基金Shandong Province Natural Science Foundation (Y2007F54)Excellent Mid-Youth Foundation of Shandong Province (2006BS04004)
文摘The distributions of the axial stress and shear stress in Al2O3-TiC/Q235 diffusion bonded joints were studied using finite element method （FEM）. The effect of interlayer thickness on the axial stress and shear stress was also investigated. The results indicate that the gradients of the axial stress and shear stress are great near the joint edge. The maximal shear stress produces at the interface of the Al2O3-TIC and Ti interlayer. With the increase of Cu interlayer thickness, the magnitudes of the axial stress and shear stress first decrease and then increase. The distribution of the axial stress changes greatly with a little change in the shear stress. The shear fracture initiates at the interface of the Al2O3-TiC/ Ti interlayer with high shear stress and then propagates to the Al2O3-TIC side, which is consistent with the stress FEM calculating results.
文摘Cucumber seedlings were sprayed with different concentrations of LaCl_3 for 3 d continuously. After 7 d of this treatment, the plants were treated with 1200 mg·L^(-1) 2,4-dichlorophennoxy(2,4-D) for 24 h. The leaves were harvested and rinsed with 5 mmol·L^(-1) EDTA. The concentrations of photosynthetic pigments, soluble protein and metabolites related to oxidative stress and the activities of antioxidant enzymes in leaves were assayed. The results show that the treatment with appropriate concentration of LaCl_3 has resistant effect on oxidative stress induced by 2, 4-D. Proper concentration of LaCl_3 promotes the activity of antioxidant system in plants and alleviates the damage caused by 2, 4-D.
文摘The time-domain BEM was developed to analyze the dynamic stress intensity factor ( DSIF) of 3-D elastodynamic crack problems. To simulate the stress singularity along the front of a crack, eight-node isoparametric singular elements were used, and the DSIF for a semi-circular surface crack was firstly calculated based on displacement equation using the time-domain BEM formulation. The new scheme to determine the time step was brought forward. By the dynamic analysis program of time-domain BEM compiled by its, several numerical examples are presented, which demonstrate the unconditional stability and high accuracy of time-domain BEM applied to 3-D elastodynamic crack problems.
文摘According to turbulent theory and characteristics of beam blank continuous casting, 3-D model to represent the flow of beam blank mould is established. The predicted results indicate that the exit obliquity of up 15°(+15°) should be adopted, which will benefit the floatation of non-metallic inclusion and purification of the molten steel. When the nozzle angle is 120°, the flow pattern is reasonable. Proper nozzle depth can be 200mm. Turbulent kinetic of meniscus can be reduced by adopting the square nozzle and suitable area of side outlet when casting speed increases. The results are consistent with those of water model experiment, so the model is exact and reasonable. The model can provide important information for design of SEN and defining of immersion depth.
文摘Applying 3-dimension finite difference method, the distribution characteristics of horizontal field transfer functions for rectangular conductor have been computed, and the law of distribution for Re-part and Im-part has been given. The influences of source field period, the conductivity, the buried depth and the length of the conductor on the transfer functions were studied. The extrema of transfer functions appear at the center, the four corners and around the edges of conductor, and move with the edges. This feature demonstrates that around the edges are best places for transfer functions' observation.
文摘In this study,the interaction between 3-D bedforms and submerged rigid vegetation has been investigated.Various laboratory experiments were conducted to study the distribution of flow velocity,Reynolds shear stress,turbulent kinetic energy,and skewness coefficients for a constant density of vegetation.Results showed that the velocity profile in the pool section deviates from those in the upstream section of the pool.It has been found that the dip parameter varied between 0.6H and 0.9H depending on various factors including bed roughness,vegetation distribution,and pool entrance/exit slopes.However,scattered vegetation in the pool and differences in slopes created non-uniform flow conditions.Also,in the wake region behind each vegetated element,flow velocity reduced significantly,and small-scale eddies are formed,causing increased perturbations.By decreasing the entrance slope and bed roughness,relatively uniform flow and weaker turbulence was resulted,but the random distribution of vegetated elements counteracted this balance and intensified turbulence.With the decrease in the pool entrance slope,the contribution of sweep event decreased and the contribution of ejection event increased.
基金This paper is supported by the National Natural Science Foundation of China （Grant Nos. 40572063 and 40272051）；the Fostering Plan Fund for Trans-Century Excellent Talents and the Project 111 （No. B07011）.
文摘The Shangzhuang altered-rock type gold ore deposit is located in the middle segment of and controlled by the Wang＇ershan fault zone in the northwestern part of the Jiaodong gold province, China. The deformation evolution, the structure of strain and stress fields and its ore-controlling effect in the Shangzhuang deposit are discussed in this paper. It is revealed that the deformation evolution has mainly undergone four phases： the early ductile deformation, the second NE-striking horizontal simple shear, the third NE-striking compression-shear and the final NW-striking compression. The mineralization happened during the third stage in which the maximum principal stress gradually transited from NE to NW. The 3-D numerical simulations of the stress field show that, on the condition that the maximum principal stress is NE-striking, the fracture development in the fault zone is favored, while when the maximum principal stress is NW-striking, the fault zone is relatively extensional and it is suitable for the influx and emplacement of ore-forming fluids. The compression-shear strain field during the mineralization is characterized by the λ-type structure, the positive flower structure, etc. Orebodies are mostly equidistantly located in the dilatational spaces, which are distributed in the integral compressional circumstances. And the dilatational spaces are developed where the fault attitude changes or shear joint systems develop. In the overall compression-shear stress field, the strain field bears self-similarity at multiple scales, including the orebody, ore deposit and orefield. The selfsimilarity of the structure comprises the subequidistant distribution of fractures at the same scale and the similar shape of the fractures at various scales. Yet, due to the special geological structure, the orebodies are mostly located in the hanging wall in the Shangzhuang deposit, which is different from most deposits in the Jiaodong gold province. Analyses of the ore-controlling stress and strain fields in the deposit provide an important basis for deposit seeking.
基金the National Institute of Standards and Technologythe Army Office of Research
文摘The Self-Similar Crack Expansion (SSCE) method is used to calculate stress intensity factors for three-dimensional cracks in an infinite medium or semi-infinite medium by the boundary integral element technique, whereby, the stress intensity factors at crack tips are determined by calculating the crack-opening displacements over the crack surface. For elements on the crack surface, regular integrals and singular integrals are precisely evaluated based on closed form expressions, which improves the accuracy. Examples shaw that this method yields very accurate results for stress intensity factors of penny-shaped cracks and elliptical cracks in the full space, with errors of less than 1% as compared with analytical solutions. The stress intensity factors of subsurface cracks ate in good agreement with other analytical solutions.
