Magnetic Nano Cobalt Ferrite Catalyzed Synthesis of 4H-Pyrano[3,2-h]quinoline Derivatives under Microwave Irradiation

A microwave irradiated magnetically separable nano cobalt ferrite catalyzed green method for the synthesis of 4-phenyl-4H-pyrano[3,2-h]quinolin-2-amine and 2-amino-4-phenyl-4H-pyrano[3,2-h] quinoline-3-carbonitrile derivatives through cyclization of aromatic aldehyde, acetonitrile/malononitrile and 8-hydoxyquinoline is developed and presented in this paper. The cubic magnetic cobalt ferrite nano particles were synthesized by sol-gel citrate precursor method and characterized by FT-IR, XRD, SEM and TEM techniques and the structures of the synthesized pyranoquinoline derivatives were assigned by IR, MASS and 1H NMR techniques. The reaction is carried out in a domestic microwave oven with a heat-resistant microwave safe glass container with a lid.

Synthesis of 3,3-Arylidene Bis(4-Hydroxycoumarin) Catalyzed by <i>p</i>-Dodecylbenzenesulfonic Acid (DBSA) in Aqueous Media and Microwave Irradiation

A series of 3,3-arylidene bis(4-hydroxycoumarins) were synthesized by the reaction of aromatic aldehydes with 4-hydroxycoumarin using dodecylbenzenesulfonic acid as Br?nsted acid-surfactant catalyst in aqueous media and under microwave irradiation. The present method is operationally simple and the use of water as the reaction medium makes the process environmentally benign.

Synthesis of α,β-Unsaturated Ketones using Potassium fluoridealumina Catalyst by Microwave Irradiation

Microwave irradiation can accelerate the rate of the synthetic reaction of α,β-unsaturated ketones by using KF-Al2O3 as catalyst. The rate enhancement of the reaction is 360-860 fold.

Microwave promoted one-pot synthesis of 3-(2′-amino-3′-cyano-4′-arylpyrid-6′-yl)coumarins

A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.

New 4-imino-4H-Chromeno[2,3-d]Pyrimidin-3(5H)-Amine: Synthesis, Cytotoxic Effects on Tumoral Cell Lines and in Silico ADMET Properties

The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was established according to their spectroscopic analysis, such as FT-IR, NMR and mass spectroscopy. These new compounds were tested for their antiproliferative activities on seven representative human tumoral cell lines (Huh7 D12, Caco2, MDA-MB231, MDA-MB468, HCT116, PC3 and MCF7) and also on fibroblasts. Among them, only the compounds 6c showed micromolar cytotoxic activity on tumor cell lines (1.8 50 50 > 25 μM). Finally, in silico ADMET studies ware performed to investigate the possibility of using of the identified compound 6c as potential anti-tumor compound.

Microwave-prompted rapid and efficient synthesis of 3-alkyl substituted imidazo[1,5-a]pyridines

Under regular heating and microwave irradiation, 3-alkyl substituted imidazo[1,5-a] pyridines were synthesized from 2,2＇- pyridil, di-2-pyridyl ketone and aliphatic aldehydes in the presence of ammonium acetate and acetic acid. Compared to the traditional heating condition, the reaction time under microwave irradiation was shorter and 3-alkyl imidazo[1,5-a]pyddines were given in higher yield.

Environmentally friendly, microwave-assisted synthesis of 5-substituted 1H-tetrazoles by recyclable CuO nanoparticles via(3+2) cycloaddition of nitriles and NaN_3

Recyclable CuO nanoparticles were successfully employed to catalyze the microwave‐assisted(3+2)cycloaddition reaction between nitriles and NaN3to efficiently synthesize5‐substituted1H‐tetrazoles.The salient features associated with this protocol are its cost effectiveness,rapid synthesis,stability,reusability,mild reaction conditions without any additives,high tolerance to various functional groups,and excellent yields under microwave irradiation.This environmentally friendly,microwave‐assisted,nanoparticle‐catalyzed synthetic methodology is seen as an alternative to conventional procedures that involve Lewis acid catalysts and a simple operation to the privileged scaffold.

Iron (III) Chloride Catalyzed Claisen Rearrangement Reaction of Allyloxyarenes under Microwave Conditions

The Claisen rearrangement is a [3,3]-sigmatropic rearrangement which is an important method for new C-C bond formation in organic synthesis. This reaction is a typical thermal reaction that requires a high temperature and long reaction time. In this paper, the acceleration effects of the iron (III) chloride (FeCl3) catalyst and microwave irradiation during the Claisen rearrangement reaction of allyloxyarene derivatives are reported. The FeCl3 catalyst was able to initiate the reaction at low temperature and induced the subsequent cyclization reaction. The moderation of excellent yields was obtained in a short reaction time. The formation of complex ferric-arenes under microwave irradiation conditions to efficiently absorb the microwaves was expected and confirmed.

Promoting effect of microwave irradiation on CeO2-TiO2 catalyst for selective catalytic reduction of NO by NH3

In this work we prepared several CeO2-TiO2 catalysts for the NH3-SCR reactionusing co-precipitation with assistance of microwave irradiation.The catalytic NH3-SCR activities over CeO2-TiO2 catalysts at low temperatures are largely enhanced by the treatment of microwave irradiation,the operation temperature window is also broadened.For better understanding the promotion mechanism,the catalyst prepared by conventional co-precipitation with and without microwave irradiation treatment was characterized with H2-TPR,NH3-TPD,XPS,XRD and BET.Microwave irradiation treatment accelerates the crystallite rate of CeO2-TiO2 catalysts,and greatly enlarges their surface area by adjusting their microstructures.The resistance to SO2 and H2O is also improved via regulating the hierarchical pore structure by the microwave irradiation.Microwave irradiation treatment can also improve the redox property and increase the acid sites over the catalyst surfaces.The result of in situ DRIFTS suggests that the microwave irradiation treatment generates more Br?nsted acid sites on CeO2-TiO2-2 h catalyst,helpful in SCR reactions.XPS results show that after microwave irradiation on the CeO2-TiO2 catalysts,the surface demonstrates an elevated concentration of chemisorbed oxygen,consequently leading to better oxidation of NO to NO2.Additionally,the molar ratio of Ce3+/Ce4+has been elevated after being treated by microwave irradiation,a vital factor in enhancing the NH3-SCR activities.

Blue-green BaAl_2O_4:Eu^(2+),Dy^(3+) phosphors synthesized via combustion synthesis method assisted by microwave irradiation

Blue-green luminescent BaAl2O4：Eu2＋,Dy3＋ phosphor powders were synthesized via combustion synthesis method assisted by microwave irradiation in air. The phosphors were characterized by X-ray diffraction （XRD）, scanning electron microscopy （SEM） and fluorescence spectrophotometer. The XRD results revealed that when the concentration of urea was over 3 times higher than theoretical quantities, a BaAl2O4 single hexagonal phase was obtained. The SEM results revealed that the surface of the BaAl2O4：Eu2＋,Dy3＋ powder samples showed lots of voids and pores. The BaAl2O4：Eu2＋,Dy3＋ phosphors exhibited a broad emission band of main peak at 496 nm and a shoulder peak at 426 nm under excitation of 337 nm. The BaAl2O4：Eu2＋,Dy3＋ phosphors at the Eu2＋ concentration of 1 mol.% showed the strongest luminescent intensity. Long afterglow phosphorescence was observed in the dark with naked eyes after the removal of the excitation source.

Negative Feedback Effect of Microwave Irradiation in the Microwave-assisted Hydrothermal Synthesis of Bi_2S_3 Nanorods

The microwave-assisted hydrothermal synthesis of Bi 2S 3 na^no^rods was reported. The result showed that microwave irradiation can help to produce Bi 2S 3 nanorods in very short time. There is a negative feedback effect which increases the degree of crystallinity in the reaction.

Amide Hydrolysis Reaction Catalyzed by KF/Al2O3 under Microwave Irradiation and Solvent Free Conditions

A microwave-enhanced hydrolysis of amides utilizing KF/Al2O3 in the absence of solvents has been developed. Amines are produced in excellent yields along with the corresponding carboxylic acids.

微波辐射KF—Al_2O_3催化合成查尔酮的研究

Reported in this paper is the synthesis of Chalcone by microwave irradiation and using KF-Al 2O 3 catalyst.As compared with conventional method,the reaction time was reduced considerably yet the yidld was good.

无溶剂无催化剂微波促进下1-苯基-3-甲基-5-吡唑啉酮与芳醛的反应研究

无溶剂无催化剂条件下 ,微波促进 1 苯基 3 甲基 5 吡唑啉酮与芳醛的缩合反应选择不同辐射功率将分别得到 4 芳亚甲基 3 甲基 1 苯基 5 吡唑啉酮和 4,4′ 芳亚甲基 -双 ( 1 苯基 3 甲基 5 吡唑啉酮 ) ,产率良好 .产物结构经1 HNMR ,1 3

微波辐射法合成的Y_2O_2S∶Eu^(3+)荧光体的定量相分析

本文应用Ｘ射线衍射Ｋ值法对Ｙ２Ｏ２Ｓ∶Ｅｕ３＋荧光体微波辐射合成产物相进行定量相分析研究，参考物相采用α－Ａｌ２Ｏ３，实验结果表明：在测定范围内最大相对偏差约－２．４％。本法测定微波合成产物相Ｙ２Ｏ２Ｓ快速、简便、实用，对优选微波合成工艺技术参数和研究微波合成过程化学有应用价值。

1,3-二噁烷环的双磺酸盐表面活性剂的微波合成

在微波辐射下,以磷钨酸为催化剂,N,N-二甲基甲酰胺为溶剂,将2,2-二羟甲基-1,3-丙二醇与醛缩合合成了单缩醛,然后与氢化钠和1,3-丙磺内酯反应得到含1,3-二噁烷环的双磺酸盐表面活性剂.产物经过元素分析、IR和1HNMR表征.

Preparation of Cu/ZnO/Al_(2)O_(3) catalyst under microwave irradiation for slurry methanol synthesis

Cu/ZnO/Al_(2)O_(3) catalysts with Cu/Zn/Al ratios of 6/3/1 were precipitated and aged by conventional and microwave heating methods and tested in the slurry phase reactor for methanol synthesis.The effect of technological condition of precipitation and aging process under microwave irradiation on the catalytic performance was investigated to optimize the preparing condition of Cu/ZnO/Al_(2)O_(3) catalyst.The results showed that the microwave irradiation during precipitation process could improve the activity of the catalyst,but had little effect on the stability.While the microwave irradiation during aging process has a great benefit to both the activity and stability of the catalyst,the catalyst aged at 80℃ for 1 h under microwave irradiation possessed higher methanol space time yield(STY)and more stable catalytic activity.The activity and stability of the catalyst was further enhanced when microwave irradiation was used in both precipitation and aging processes;the optimized condition for the catalyst precursor preparation was precipitation at 60℃ and aging at 80℃ under microwave irradiation.

2，3，3a，4．四氢硫色烯并[4，3-c]吡唑类化合物的合成及其体外抗真菌活性研究

目的设计合成2,3,3a,4-四氢硫色烯并[4,3-c]吡唑类化合物,并对其体外抗真菌活性进行初步评价。方法以取代苯硫酚为起始原料,合成中间体3-次苄基硫色满酮,该中间体与水合肼在热醋酸中反应生成目标化合物。采用二倍稀释法对4种受试真菌——絮状表皮毛癣菌(E.floccosum)、石膏样小孢子菌(M.gypse-um)、绿色木霉菌(T.viride)和断发毛癣菌(T.tonsurans)进行体外抗真菌活性测试。结果合成了12个新的2,3,3a,4-四氢硫色烯并[4,3-c]吡唑类化合物,其结构经氢核磁共振谱、质谱和元素分析确证。抗真菌实验结果表明,所合成的目标化合物对供试真菌具有一定程度的抑制活性。结论2,3,3a,4-四氢硫色烯并[4,3-c]吡唑类化合物具有体外抗真菌活性。

无溶剂微波促进下1-苯基-3-甲基-5-吡唑啉酮与芳酰氯的反应研究

无溶剂条件下 ,微波促进 1 苯基 3 甲基 5 吡唑啉酮与等量的酰氯反应 ,可高产率简便得到 5 酰化产物 .在有氢氧化钙存在时与 2倍量的酰氯反应主要得到 4 ,5 位酰化产物 .产物结构经1HNMR ,13 CNMR ,IR 。

N-芳基-2-乙基-3-羟基-4-吡啶酮的微波合成

用微波辐射从 2 乙基 3 羟基 4 吡喃酮和芳胺合成了系列N 芳基 2 乙基 3 羟基 4 吡啶酮 ,并对产物进行了紫外、红外、氢核磁和质谱表征 .