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Lie symmetry analysis and invariant solutions for the(3+1)-dimensional Virasoro integrable model
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作者 胡恒春 李雅琦 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第4期249-254,共6页
Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with a... Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically. 展开更多
关键词 (3+1)-dimensional Virasoro integrable model Lie symmetry invariant solutions
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Interaction solutions for the second extended(3+1)-dimensional Jimbo–Miwa equation
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作者 马红彩 毛雪 邓爱平 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第6期112-121,共10页
Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions be... Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions. 展开更多
关键词 Hirota bilinear method second extended(3+1)-dimensional Jimbo–Miwa equation lump solution interaction solution
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类风湿关节炎患者血清SAA、CCL20、MMP-3表达水平及临床意义
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作者 霍月红 郭燕羽 王贯虹 《临床和实验医学杂志》 2024年第5期497-501,共5页
目的探讨类风湿关节炎(RA)患者血清淀粉样蛋白A(SAA)、趋化因子配体20(CCL20)及基质金属蛋白酶3(MMP-3)水平变化及临床意义。方法回顾性选取2020年9月至2023年1月大同市第五人民医院收治的RA患者108例作为研究对象,依据28个关节的疾病... 目的探讨类风湿关节炎(RA)患者血清淀粉样蛋白A(SAA)、趋化因子配体20(CCL20)及基质金属蛋白酶3(MMP-3)水平变化及临床意义。方法回顾性选取2020年9月至2023年1月大同市第五人民医院收治的RA患者108例作为研究对象,依据28个关节的疾病活动度评分(DAS28)评分,将患者分为缓解期组(n=35,DSA28评分<2.6)与活动期组(n=73,DSA28评分≥2.6),并将活动期患者进一步分为轻度活动期(n=20,DSA28评分2.6~3.2)、中度活动期(n=29,DSA28评分>3.2~5.1)与重度活动期(n=24,DSA28为>5.1);另选取同期健康体检者80名作为对照组。所有受试者均检测血清SAA、CCL20、MMP-3水平。比较不同组别血清SAA、CCL20、MMP-3水平;使用Pearson相关分析血清SAA、CCL20、MMP-3水平与红细胞沉降率(ESR)、C反应蛋白(CRP)的相关性;使用受试者工作特征(ROC)曲线评价各指标对RA疾病活动度的诊断价值。结果RA组血清SAA、CCL20、MMP-3水平分别为(42.25±13.46)mg/L、(45.69±12.78)pg/mL、(85.41±25.14)ng/mL,均显著高于对照组[(7.14±2.12)mg/L、(18.12±5.47)pg/mL、(27.36±8.21)ng/mL],差异均有统计学意义(P<0.05)。RA活动期组患者血清SAA、CCL20、MMP-3水平分别为(51.78±10.71)mg/L、(53.14±10.45)pg/mL、(106.10±20.39)ng/mL,显著高于缓解期组[(22.37±7.14)mg/L、(30.15±8.24)pg/mL、(42.25±13.64)ng/mL],差异均有统计学意义(P<0.05)。重度活动度组血清SAA、CCL20、MMP-3水平均高于中度活动度组和轻度活动度组,差异均有统计学意义(P<0.05),随着疾病活动度提高,血清SAA、CCL20、MMP-3水平逐渐增高。Pearson相关分析显示,活动期RA患者血清SAA、CCL20、MMP-3水平与CRP、ESR均呈正相关(P<0.05)。ROC曲线分析得出,血清SAA、CCL20、MMP-3区分RA轻度活动度与中度活动度的曲线下面积(AUC)分别为0.852、0.756、0.725,区分中度活动度与重度活动度的AUC分别为0.852、0.756、0.725,均显示出一定的诊断能力。结论RA患者血清SAA、CCL20、MMP-3水平均呈高表达,这3项指标可作为评估疾病活动度的生物标志物,可为临床预测病情进展提供参考。 展开更多
关键词 类风湿关节炎 疾病活动度 淀粉样蛋白A 趋化因子配体20 基质金属蛋白酶3
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慢性肾脏病患者血清CHI3L1、MMP-13表达水平及其病情评估、预后价值
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作者 唐方平 刘义强 +1 位作者 李娜 付平 《国际检验医学杂志》 CAS 2024年第9期1101-1105,共5页
目的探讨慢性肾脏病患者血清几丁质酶3样蛋白1(CHI3L1)、基质金属蛋白酶-13(MMP-13)表达水平及病情评估、预后价值。方法选取2020年3月至2022年8月在江油市人民医院就诊的208例慢性肾脏病患者作为病例组,按照病情严重程度将208例慢性肾... 目的探讨慢性肾脏病患者血清几丁质酶3样蛋白1(CHI3L1)、基质金属蛋白酶-13(MMP-13)表达水平及病情评估、预后价值。方法选取2020年3月至2022年8月在江油市人民医院就诊的208例慢性肾脏病患者作为病例组,按照病情严重程度将208例慢性肾脏病患者分为Ⅰ期组21例、Ⅱ期组42例、Ⅲ期组86例、Ⅳ期组38例、Ⅴ期组21例。另选取同期152例体检健康者作为对照组。根据患者预后情况将208例患者分为预后良好组(n=92)及预后不良组(n=116)。收集受试人员一般资料,采用酶联免疫吸附试验检测血清CHI3L1、MMP-13表达水平,Pearson法分析慢性肾脏病患者血清CHI3L1、MMP-13表达水平的相关性,以及二者与肾小球滤过率(GFR)的相关性,采用Cox回归分析影响慢性肾脏病患者预后的因素。结果对照组、病例组年龄、性别等一般资料比较,差异无统计学意义(P>0.05);病例组患者血清中CHI3L1表达水平较对照组显著增加,但MMP-13表达水平显著降低,差异有统计学意义(P<0.05);随着病情分期增加,患者血清CHI3L1表达水平随之增加,MMP-13表达水平随之降低(P<0.05);预后不良组患者血清CHI3L1表达水平较预后良好组显著增加,MMP-13表达水平显著降低(P<0.05);Pearson法分析显示,慢性肾脏病患者血清CHI3L1、MMP-13表达水平呈负相关,CHI3L1表达水平与GFR呈负相关,MMP-13表达水平与GFR呈正相关(P<0.05)。Cox回归分析显示,血清CHI3L1、MMP-13、GFR为慢性肾脏病患者预后不良的独立影响因素(P<0.05)。结论慢性肾脏病患者血清CHI3L1表达水平升高,MMP-13表达水平降低,二者均可用于病情及预后评估。 展开更多
关键词 慢性肾脏病 几丁质酶3样蛋白1 基质金属蛋白酶-13
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3D打印技术用于经鼻蝶窦入路垂体腺瘤切除术应用效果及对血清MMP-9和IGF-1水平的影响
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作者 韩莹 陈兴河 +2 位作者 王永恒 赵锦程 吴磊 《中国医学装备》 2024年第4期112-116,共5页
目的:探究3D打印技术在经鼻蝶窦入路垂体腺瘤(PA)切除术的应用效果及对血清基质金属蛋白酶-9(MMP-9)和胰岛素样生长因子-1(IGF-1)水平的影响。方法:选取2020年5月至2022年5月秦皇岛市第一医院收治的84例PA患者,按照随机数表法将其分为... 目的:探究3D打印技术在经鼻蝶窦入路垂体腺瘤(PA)切除术的应用效果及对血清基质金属蛋白酶-9(MMP-9)和胰岛素样生长因子-1(IGF-1)水平的影响。方法:选取2020年5月至2022年5月秦皇岛市第一医院收治的84例PA患者,按照随机数表法将其分为观察组和对照组,每组42例。对照组行经鼻蝶窦入路垂体腺瘤切除术,观察组行经鼻蝶窦入路垂体腺瘤切除术联合应用3D打印技术,比较两组肿瘤切除效果、围术期指标、视力改善情况、MMP-9和IGF-1水平,以及鼻腔功能的鼻气道阻力(NAR)、T&T嗅觉测试评分及并发症。结果:观察组肿瘤切除效果优于对照组,差异有统计学意义(U=2.286,P<0.05);观察组手术时间、术中出血量及住院时间均少于对照组,差异有统计学意义(t=4.780、11.438、11.842,P<0.05);术后3 d、7 d时观察组血清MMP-9和IGF-1水平低于对照组,差异有统计学意义(F=7.526、4.985,P<0.05);术后1个月、3个月时观察组NAR及T&T嗅觉测试评分低于对照组,差异有统计学意义(F=6.359、8.436,P<0.05);两组视力视野改善情况及并发症发生率比较,差异无统计学意义(P>0.05)。结论:3D打印技术用于经鼻蝶窦入路垂体腺瘤切除术可提高肿瘤切除效果,优化手术操作,减少创伤,有利于减轻疼痛,改善嗅觉功能与视力视野,并能降低血清MMP-9、IGF-1水平,且安全性较高。 展开更多
关键词 垂体腺瘤 经鼻蝶窦入路垂体腺瘤(PA)切除术 3D打印技术 基质金属蛋白酶-9(MMP-9) 胰岛素样生长因子-1(IGF-1)
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Comparative Assessment on Microstructure and Properties of in-situ TiC+Ti_(5)Si_(3)Reinforced TiAl-Sn-Zr Matrix Composites by Spark Plasma Sintering and Argon Protected Sintering 被引量:1
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作者 姚辉 许晓静 +4 位作者 CAI Chengbin LI Chen CHEN Fenghua LIU Yangguang XIAO Yishui 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2023年第1期199-205,共7页
The effects of SiC particles(SiCp)on high temperature oxidation behavior of titanium matrix composites(TMCs)under different powder metallurgy processes were investigated.In situ Ti C+Ti_(5)Si_(3)reinforced titanium ma... The effects of SiC particles(SiCp)on high temperature oxidation behavior of titanium matrix composites(TMCs)under different powder metallurgy processes were investigated.In situ Ti C+Ti_(5)Si_(3)reinforced titanium matrix composites were prepared by discharge plasma sintering(SPS)and argon protective sintering(APS).The results show that the two processes have a negligible effect on the composition and hardness of the samples,but the hardness of the two samples is significantly improved by adding SiCp.The apparent porosity of SPS process is obviously smaller than that of APS process,whereas,the apparent porosity increases slightly with the addition of SiCp.The oxide layer thickness and mass gain of the samples obtained by SPS process are smaller than those obtained by APS process.The oxide thickness and mass gain of both processes are further reduced by adding SiCp.The SPS composites showed the best high temperature oxidation resistance.Therefore,TMCs with Si Cp by SPS can effectively improve the high-temperature oxidation behavior of the materials. 展开更多
关键词 powder metallurgy titanium matrix composites High-temperature oxidation TiC and Ti_(5)Si_(3) Ti-Al-Sn-Zr
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A 3-DIMENSIONAL DATA MODEL FOR VISUALIZING CLOVERLEAF JUNCTION IN A CITY MODEL 被引量:6
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作者 Chen Jun Sun Min Zhou Qiming 《Geo-Spatial Information Science》 1999年第1期9-15,共7页
The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its ma... The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data 展开更多
关键词 3-dimensional CITY MODEL (3DCM) GIS cloverleaf JUNCTION DATA STRUCTURE DATABASE
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Evaluation of Airway Obstruction at Soft Palate Level in Male Patients with Obstructive Sleep Apnea/Hypopnea Syndrome:Dynamic 3-Dimensional CT Imaging of Upper Airway 被引量:10
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作者 肖英 陈雄 +4 位作者 史河水 杨阳 何烈纯 董家琪 孔维佳 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2011年第3期413-418,共6页
This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A tota... This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller's maneuver.The soft palate length(SPL),the minimal cross-sectional area of the retropalatal region(mXSA-RP),and the vertical distance from the hard palate to the upper posterior part of the hyoid(hhL) were compared between the two breathing states.These parameters,together with hard palate length(HPL),were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index(AHI) and the lowest saturation of blood oxygen(LSaO2)] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller's maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters(except the position of the hyoid bone) between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index(BMI)≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller's maneuver than those in group with BMI26(P0.05 for all).It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26. 展开更多
关键词 obstructive sleep apnea/hypopnea syndrome upper airway obstruction soft palate level dynamic computed tomography 3-dimensional imaging
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NOVEL 6-SPS PARALLEL 3-DIMENSIONAL PLATFORM MANIPULATOR AND ITS FORCE/MOTION TRANSMISSION ANALYSIS 被引量:2
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作者 Jin Zhenlin School of Mechanical Engineering, Yanshan University, Qinhuangdao 066004, ChinaGao Feng Hebei University of Technology 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2002年第4期298-302,共5页
The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmissio... The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers. 展开更多
关键词 6-SPS parallel manipulator 3-dimensional platform manipulator ISOTROPY
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Residual symmetry, CRE integrability and interaction solutions of two higher-dimensional shallow water wave equations
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作者 刘希忠 李界通 俞军 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第11期313-319,共7页
Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of t... Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated. 展开更多
关键词 (3+1)-dimensional shallow water wave equation residual symmetry consistent Riccati expansion
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Thermal effect on endurance performance of 3-dimensional RRAM crossbar array 被引量:2
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作者 卢年端 孙鹏霄 +4 位作者 李泠 刘琦 龙世兵 吕杭炳 刘明 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第5期253-257,共5页
Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability... Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability mechanisms of the3 D RRAM array has become a field of intense research. In this work, the endurance performance of the 3D 1D1 R crossbar array under the thermal effect is investigated in terms of numerical simulation. It is revealed that the endurance performance of the 3D 1D1 R array would be seriously deteriorated under thermal effects as the feature size scales down to a relatively small value. A possible method to alleviate the thermal effects is provided and verified by numerical simulation. 展开更多
关键词 3-dimensional resistive random access memory(RRAM) thermal effect endurance performance
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Rota-Baxter Operators on 3-dimensional Lie Algebras and Solutions of the Classical Yang-Baxter Equation 被引量:1
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作者 Cheng Yong-sheng Wu Lin-li +1 位作者 Wang Pan-yin Du Xian-kun 《Communications in Mathematical Research》 CSCD 2019年第1期81-96,共16页
In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-... In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-dimensional Lie algebras g ■ _(ad~*) g~* and some new structures of left-symmetric algebra induced from g and its Rota-Baxter operators. 展开更多
关键词 Rota-Baxter OPERATORS 3-dimensional Lie ALGEBRA classical Yang-Baxter equation left-symmetric ALGEBRA
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1060Al/Al-Al_(2)O_(3)/1060Al层状铝基复合材料热变形模型对比分析
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作者 郝朋程 张兵 +6 位作者 张志娟 赵田丽 刘广龙 陈乐 徐依 蔡军 王快社 《塑性工程学报》 CAS CSCD 北大核心 2024年第3期107-118,共12页
采用Gleeble-3500热模拟试验机在变形温度为25~400℃、应变速率为0.01~10s^(-1)和真应变为0.85的条件下,对1060Al/Al-Al_(2)O_(3)/1060Al层状铝基复合材料进行了热压缩试验,研究其热变形行为,建立了应变补偿的Arrhenius (SCA)、修正的Jo... 采用Gleeble-3500热模拟试验机在变形温度为25~400℃、应变速率为0.01~10s^(-1)和真应变为0.85的条件下,对1060Al/Al-Al_(2)O_(3)/1060Al层状铝基复合材料进行了热压缩试验,研究其热变形行为,建立了应变补偿的Arrhenius (SCA)、修正的Johnson-Cook (MJC)和修正的Zerilli-Armstrong (MZA) 3种本构模型,并对流变应力的预测值与实验值进行对比。结果表明,层状复合材料流变应力呈加工硬化型,并随温度升高或应变速率降低而降低;在100℃/0.5s^(-1)、200℃/0.1s^(-1)和300℃/0.1s^(-1)条件下,层状复合材料组元层间变形较为协调;3种本构模型中,MZA模型的相关系数最高,R为0.99085、平均绝对相对误差最低,e_(AARE)为0.046966,更适合描述1060Al/Al-Al_(2)O_(3)/1060Al层状铝基复合材料的热变形行为。 展开更多
关键词 1060Al/Al-Al_(2)O_(3)/1060Al层状铝基复合材料 流变应力 宏观形貌 本构方程
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Extended symmetry transformation of (3+1)-dimensional generalized nonlinear Schrdinger equation with variable coefficients 被引量:1
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作者 荆建春 李彪 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第1期77-83,共7页
In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach... In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach and symbolic computation. Then based on the extended symmetry, some 3D variable coefficient NLS equations are reduced to other variable coefficient NLS equations or the constant coefficient 3D NLS equation. By using these symmetry transformations, abundant exact solutions of some 3D NLS equations with distributed dispersion, nonlinearity, and gain or loss are obtained from the constant coefficient 3D NLS equation. 展开更多
关键词 3+1)-dimensional nonlinear Schrodinger equation extended symmetry exact solution symbolic computation
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GM130通过14-3-3ζ对卵巢癌细胞增殖的影响及机制研究
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作者 郑依果 易永芬 罗祎 《中国肿瘤外科杂志》 CAS 2024年第2期170-177,共8页
目的探讨高尔基体基质蛋白130(GM130)通过14-3-3ζ对卵巢癌细胞增殖的影响及可能机制。方法采用免疫组化法检测在20例正常卵巢上皮组织和42例卵巢上皮恶性肿瘤中GM130和14-3-3ζ的表达,分析二者相关性。采用Western blot和RT-PCR法检测... 目的探讨高尔基体基质蛋白130(GM130)通过14-3-3ζ对卵巢癌细胞增殖的影响及可能机制。方法采用免疫组化法检测在20例正常卵巢上皮组织和42例卵巢上皮恶性肿瘤中GM130和14-3-3ζ的表达,分析二者相关性。采用Western blot和RT-PCR法检测卵巢癌SKOV3/A2780细胞株GM130和14-3-3ζ蛋白及其mRNA表达情况,筛选出高表达细胞株。采用免疫荧光染色法检测GM130与14-3-3ζ在卵巢癌细胞中的共表达情况。将设计好的重组表达质粒shRNA-GM130片段稳转进入卵巢癌细胞中,采用Western blot和RT-PCR筛选出降低GM130的最佳片段。细胞分为三组:空白组(WT)、对照组(NC)、低表达组(313),采用CCK法和流式细胞术分别检测各组卵巢癌细胞生殖情况及周期变化情况,采用Western blot法检测各组14-3-3ζ、GRASP65、P115及增殖相关蛋白表达水平。结果GM130和14-3-3ζ在卵巢恶性肿瘤组织中的表达水平高于正常卵巢组织(P<0.001)。在卵巢恶性肿瘤组织中,GM130和14-3-3ζ呈正相关关系(r=0.873,P<0.001)。GM130蛋白及其mRNA在SKOV3细胞中的表达量高于A2780细胞(P<0.05),14-3-3ζ蛋白及其mRNA在SKOV3细胞和A2780细胞中比较差异无统计学意义(P>0.05)。后续实验选用SKOV3细胞。免疫荧光共定位染色显示,GM130与14-3-3ζ主要在胞质表达,前者近核膜部分呈堆叠样表达量较高,后者胞核中表达较少,二者可能存在共定位关系。转染313组片段后,对GM130的抑制效果最好。转染质粒313组细胞增殖能力降低,细胞在G1期阻滞的数量增多,G2期阻滞数量减少,S期阻滞的细胞数量稍减少,GM130、14-3-3ζ、P115、Cyclin A、Cdc25A蛋白相对表达水平降低,P21蛋白相对表达水平升高(P<0.05)。结论抑制GM130可抑制卵巢癌细胞增殖,其机制可能与抑制14-3-3ζ表达,影响卵巢癌细胞周期有关。 展开更多
关键词 卵巢癌 高尔基体基质蛋白130 14-3-3ζ 细胞增殖 细胞周期
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Interactions among special embed-solitons for the (3+1)-dimensional Burgers equation 被引量:1
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作者 张雯婷 戴朝卿 陈未路 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第4期196-199,共4页
With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions ... With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions in the variable separation solution, we discuss the interaction behaviors among taper-like, plateau-type rings, and rectangle-type embed-solitons in the periodic wave background. All the interaction behaviors are completely elastic, and no phase shift appears after interaction. 展开更多
关键词 3+1)-dimensional Burgers equation modified mapping method interaction between special embed-solitons
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Symmetry analysis and explicit solutions of the (3+1)-dimensional baroclinic potential vorticity equation 被引量:1
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作者 胡晓瑞 陈勇 黄菲 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第8期35-45,共11页
This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmet... This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmetry algebra, symmetry group and group-invariant solutions are analysed. Otherwise, some exact explicit solutions are obtained from the corresponding (2+1)-dimensional equation, the inviscid barotropic nondivergent vorticy equation. To show the properties and characters of these solutions, some plots as well as their possible physical meanings of the atmospheric circulation are given out. 展开更多
关键词 3+1)-dimensional nonlinear baroclinic potential vorticity equation symmetry group group-invariant solution explicit solution
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A more general form of lump solution,lumpoff,and instanton/rogue wave solutions of a reduced (3+1)-dimensional nonlinear evolution equation 被引量:2
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作者 郑攀峰 贾曼 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第12期147-156,共10页
In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution ... In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution to the special case for z=x.Furthermore,a more general form of lump solution of the equation is found which possesses seven arbitrary parameters and four constraint conditions.By cutting the lump by the induced soliton(s),lumpoff and instanton/rogue wave solutions are also constructed by the more general form of lump solution. 展开更多
关键词 a reduced(3 + 1)-dimensional nonlinear evolution equation more general form of lump solution soliton induced by lump lumpoff and instanton/rogue wave solutions
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New exact solutions of a (3+1)-dimensional Jimbo-Miwa system 被引量:1
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作者 陈元明 马松华 马正义 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第5期247-251,共5页
By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we o... By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we obtain some special localized excitations and study the interactions between two solitary waves of the system. 展开更多
关键词 3+1)-dimensional Jimbo-Miwa system (G'/G)-expansion method exact solutions interactionsbetween two solitary waves
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Wronskian Determinant Solutions for the (3 + 1)-Dimensional Boiti-Leon-Manna-Pempinelli Equation 被引量:1
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作者 Hongcai Ma Yongbin Bai 《Journal of Applied Mathematics and Physics》 2013年第5期18-24,共7页
In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using th... In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using the Wronskian technique, which include rational solutions, soliton solutions, positons and negatons. 展开更多
关键词 (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli EQUATION The WRONSKIAN Technique Soliton Negaton Positon
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