期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Isolation and Stucture Elucidation of Diterpenes from Wedelia prostrata and Their Cytotoxicity Activities
1
作者 CHEN Qing LIN Jianhong +1 位作者 ZHAO Dan ZHU Xuan 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2016年第5期792-796,共5页
In this paper, a new diterpene together with seven known diterpenes was isolated from Wedelia prostrata. The chemical structure of the new compound was elucidated via 1D and 2D nuclear magnetic resonance(NMR) tech- ... In this paper, a new diterpene together with seven known diterpenes was isolated from Wedelia prostrata. The chemical structure of the new compound was elucidated via 1D and 2D nuclear magnetic resonance(NMR) tech- niques and mass spectrometry and identified to be 3a-phenylpropionoyloxy-ent-kaur-16-en-oic acid(l). The isolated diterpenes were tested for their cytotoxicity activities via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro- mide(MTT) assay. The results show that compounds 1, 2, 3, 4 and 6 exhibit different levels of cytotoxic activities. Especially, compound 2 shows significant cytotoxicity toward HeLa and A549 cell lines(IC50=6.14 and 8.76 μmol/L). 展开更多
关键词 Wedelia prostrata 3a-phenylpropionoyloxy-ent-kaur-16-en-oic acid Chemical constituent Cytotoxicityactivity
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部