5,6-Dihydrothieno[3＇,2＇：4,5]thieno[2,3-d]pyrimidin-4（3H）-ones 6 were synthesized in yields of 71-87% by a consecutive method, which includes aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to gi...5,6-Dihydrothieno[3＇,2＇：4,5]thieno[2,3-d]pyrimidin-4（3H）-ones 6 were synthesized in yields of 71-87% by a consecutive method, which includes aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to give carbodiimide 4 and subsequent reaction of 4 with various amines, phenols or alcohols in the presence of catalytic amount of sodium ethoxide or solid potassium carbonate. 2009 Ming Wu Ding. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.展开更多
3,5,6,8-Tetrahydro-4H-thiopyrano[4＇,3＇：4,5]thieno[2,3-d]pyrimidin-4-ones（7） were synthesized via the base catalytic reactions of amines or phenols with carbodiimides（5）, which were obtained from the aza-Wittig ...3,5,6,8-Tetrahydro-4H-thiopyrano[4＇,3＇：4,5]thieno[2,3-d]pyrimidin-4-ones（7） were synthesized via the base catalytic reactions of amines or phenols with carbodiimides（5）, which were obtained from the aza-Wittig reac tions of iminophosphoranes（4） with aromatic isocyanates.展开更多
A series of novel fused tetracyclic benzo[4,5]imidazo[1,2-a]thiopyrano[3,4-d]pyrimidin-4（3H）-one derivatives were synthesized via the reaction of aryl aldehyde, 2H-thiopyran-3,5（4H,6H）-dione, and 1H-benzo[d]imidaz...A series of novel fused tetracyclic benzo[4,5]imidazo[1,2-a]thiopyrano[3,4-d]pyrimidin-4（3H）-one derivatives were synthesized via the reaction of aryl aldehyde, 2H-thiopyran-3,5（4H,6H）-dione, and 1H-benzo[d]imidazol-2- amine in glacial acetic acid. This protocol features mild reaction conditions, high yields and short reaction time.展开更多
基金support of this work by the National Natural Science Foundation of China(No.20772041)Key Project of Science and Technology of Ministry of Education of China(No.107082)
文摘5,6-Dihydrothieno[3＇,2＇：4,5]thieno[2,3-d]pyrimidin-4（3H）-ones 6 were synthesized in yields of 71-87% by a consecutive method, which includes aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to give carbodiimide 4 and subsequent reaction of 4 with various amines, phenols or alcohols in the presence of catalytic amount of sodium ethoxide or solid potassium carbonate. 2009 Ming Wu Ding. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
基金Supported by the National Natural Science Foundation of China(No.20772041)the Key Project of Chinese Ministry of Education(No.107082)
文摘3,5,6,8-Tetrahydro-4H-thiopyrano[4＇,3＇：4,5]thieno[2,3-d]pyrimidin-4-ones（7） were synthesized via the base catalytic reactions of amines or phenols with carbodiimides（5）, which were obtained from the aza-Wittig reac tions of iminophosphoranes（4） with aromatic isocyanates.
基金Project supported by the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions （09KJA430003）, Natural Science Foundation of Xuzhou City （XM09B016）, Graduate Foundation of Xuzhou Normal University （09YLB030） and Qing Lan Project （08QLT001）.
文摘A series of novel fused tetracyclic benzo[4,5]imidazo[1,2-a]thiopyrano[3,4-d]pyrimidin-4（3H）-one derivatives were synthesized via the reaction of aryl aldehyde, 2H-thiopyran-3,5（4H,6H）-dione, and 1H-benzo[d]imidazol-2- amine in glacial acetic acid. This protocol features mild reaction conditions, high yields and short reaction time.
