目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将...目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将其分为马尔尼菲篮状菌感染确诊组(血或组织液培育养出马尔尼菲篮状菌),简称A组(62例),及马尔尼菲篮状菌感染临床诊断组[根据临床症状、体征、血常规及(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞多指标诊断],简称B组(58例)。检测患者(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞的表达水平,采用受试者工作特征(receiver-operating characteristic,ROC)曲线下面积(area under the curve,AUC)评估上述指标联合检测对艾滋病患者感染马尔尼菲篮状菌的诊断效能。结果A组的(1-3)-β-D葡聚糖和PCT水平均高于B组,CD4^(+)T淋巴细胞个数低于B组(P<0.05);(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞联合检测的AUC为0.933,(1-3)-β-D葡聚糖单独检测的AUC是0.812,PCT单独检测的AUC为0.883,CD4^(+)T淋巴细胞单独检测的AUC是0.810,(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的AUC皆优于三项单独检测,表明(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的诊断价值皆优于单一指标诊断,且联合检测的特异度、约登指数分别为92.43%和0.580,均高于三项单独检测。结论(1-3)-β-D葡聚糖联合PCT和CD4^(+)T淋巴细胞多指标对艾滋病马尔尼菲篮状菌感染具有非常高的临床诊断价值,能够帮助医生分析出高危风险患者,及时制定治疗方案,同时也承担预后效果的判断依据,对治疗艾滋病马尔尼菲篮状菌感染具有非常重要的研究价值。展开更多
This paper presents the design and testing of a 15 Gbps non-return-to-zero(NRZ),30 Gbps 4-level pulse amplitude modulation(PAM4)configurable laser diode driver(LDD)implemented in 0.15-μm GaAs E-mode pHEMT technology....This paper presents the design and testing of a 15 Gbps non-return-to-zero(NRZ),30 Gbps 4-level pulse amplitude modulation(PAM4)configurable laser diode driver(LDD)implemented in 0.15-μm GaAs E-mode pHEMT technology.The driver bandwidth is enhanced by utilizing cross-coupled neutralization capacitors across the output stage.The output transmission-line back-termination,which absorbs signal reflections from the imperfectly matched load,is performed passively with on-chip 50-Ωresistors.The proposed 30 Gbps PAM4 LDD is implemented by combining two 15 Gbps-NRZ LDDs,as the high and low amplification paths,to generate PAM4 output current signal with levels of 0,40,80,and 120 mA when driving 25-Ωlasers.The high and low amplification paths can be used separately or simultaneously as a 15 Gbps-NRZ LDD.The measurement results show clear output eye diagrams at speeds of up to 15 and 30 Gbps for the NRZ and PAM4 drivers,respectively.At a maximum output current of 120 mA,the driver consumes 1.228 W from a single supply voltage of-5.2 V.The proposed driver shows a high current driving capability with a better output power to power dissipation ratio,which makes it suitable for driving high current distributed feedback(DFB)lasers.The chip occupies a total area of 0.7×1.3 mm^(2).展开更多
Coal working face is damaged more and more seriously by water below the coal face floor. Therefore, floor water detection is a must in the process of extraction. This article aims to introducing application and princi...Coal working face is damaged more and more seriously by water below the coal face floor. Therefore, floor water detection is a must in the process of extraction. This article aims to introducing application and principle of the two-gateways parallel 3-D electrical technology and the arrangement of the observation system. The authors use this method to detect the water under the floor of a mine in north of Anhui. The results show that the two-gateways parallel 3-D electrical technology can accurately locate the water-rich areas, providing the basis for drilling drainage and grouting construction.展开更多
The self-reinforced Si<sub>3</sub>N<sub>4</sub> ceramics which contain Y<sub>2</sub>O<sub>3</sub> and La<sub>2</sub>O<sub>3</sub> additives have ...The self-reinforced Si<sub>3</sub>N<sub>4</sub> ceramics which contain Y<sub>2</sub>O<sub>3</sub> and La<sub>2</sub>O<sub>3</sub> additives have beenprepared by hot-pressing. Under the optimum processing conditions, this material has theflexural strength of 960～1050MPa and the fracture toughness of 11.17～12.74MPa·m<sup>1/2</sup> atroom-temperature, and 720～780MPa and 22～24MPa·m<sup>1/2</sup> at 1350℃. The effects of heating rate, sintering temperature, and holding time on the microstructures and mechanical properties are investigated. The experimental results show that an appropriate β-Si<sub>3</sub>N<sub>4</sub> grainsize and homogeneous microstructure can be obtained under the conditions of a heating rate of 10℃/min, sintering temperature of 1800℃, and holding time of 1h, which are advantageous to enhancing the mechanical properties. Crack deflection in large rodlike β-Si<sub>3</sub>N<sub>4</sub> grains is a principle source of toughening.展开更多
The paper deals with the application of 3 -D visible technology to reservoir management. Making use of this method for expanding - spread data point in reservoir management, can discard the false and retain the true d...The paper deals with the application of 3 -D visible technology to reservoir management. Making use of this method for expanding - spread data point in reservoir management, can discard the false and retain the true during data recording. As a result, The quality of data recording is ensured. In reservoir description, the reservoir characteristics, such as space distribution,physical change and fluid distribution may be identified by restoring palaeostructures, building - up 3-D facics tract model and 3-D fracture system model. Seismic interpretation, geologic modeling and numerical simulation are well integrated so that they can be promote reservoir performance management to develop into the intensive management pattern.展开更多
The mobile multicast technology has been a research hotspot in the wireless Internet field in recent years.Quite a large part of its applications requires the reliability in a mobile environment to be equivalent to th...The mobile multicast technology has been a research hotspot in the wireless Internet field in recent years.Quite a large part of its applications requires the reliability in a mobile environment to be equivalent to that provided by wireline links.However,the inherent features of a mobile environment,that is,high error rate of links and dynamically changing multicast members’ locations,are great difficulties for mobile multicast,let alone reliable mobile multicast.The IPv4-based reliable mobile multicast algorithms come with two different design philosophies.A part of the algorithms is to be improved for better reliability by solving existing algorithm-related problems;while other algorithms are to implement reliable mobile multicast with new function entities introduced to guarantee reliability.展开更多
文摘目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将其分为马尔尼菲篮状菌感染确诊组(血或组织液培育养出马尔尼菲篮状菌),简称A组(62例),及马尔尼菲篮状菌感染临床诊断组[根据临床症状、体征、血常规及(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞多指标诊断],简称B组(58例)。检测患者(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞的表达水平,采用受试者工作特征(receiver-operating characteristic,ROC)曲线下面积(area under the curve,AUC)评估上述指标联合检测对艾滋病患者感染马尔尼菲篮状菌的诊断效能。结果A组的(1-3)-β-D葡聚糖和PCT水平均高于B组,CD4^(+)T淋巴细胞个数低于B组(P<0.05);(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞联合检测的AUC为0.933,(1-3)-β-D葡聚糖单独检测的AUC是0.812,PCT单独检测的AUC为0.883,CD4^(+)T淋巴细胞单独检测的AUC是0.810,(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的AUC皆优于三项单独检测,表明(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的诊断价值皆优于单一指标诊断,且联合检测的特异度、约登指数分别为92.43%和0.580,均高于三项单独检测。结论(1-3)-β-D葡聚糖联合PCT和CD4^(+)T淋巴细胞多指标对艾滋病马尔尼菲篮状菌感染具有非常高的临床诊断价值,能够帮助医生分析出高危风险患者,及时制定治疗方案,同时也承担预后效果的判断依据,对治疗艾滋病马尔尼菲篮状菌感染具有非常重要的研究价值。
文摘This paper presents the design and testing of a 15 Gbps non-return-to-zero(NRZ),30 Gbps 4-level pulse amplitude modulation(PAM4)configurable laser diode driver(LDD)implemented in 0.15-μm GaAs E-mode pHEMT technology.The driver bandwidth is enhanced by utilizing cross-coupled neutralization capacitors across the output stage.The output transmission-line back-termination,which absorbs signal reflections from the imperfectly matched load,is performed passively with on-chip 50-Ωresistors.The proposed 30 Gbps PAM4 LDD is implemented by combining two 15 Gbps-NRZ LDDs,as the high and low amplification paths,to generate PAM4 output current signal with levels of 0,40,80,and 120 mA when driving 25-Ωlasers.The high and low amplification paths can be used separately or simultaneously as a 15 Gbps-NRZ LDD.The measurement results show clear output eye diagrams at speeds of up to 15 and 30 Gbps for the NRZ and PAM4 drivers,respectively.At a maximum output current of 120 mA,the driver consumes 1.228 W from a single supply voltage of-5.2 V.The proposed driver shows a high current driving capability with a better output power to power dissipation ratio,which makes it suitable for driving high current distributed feedback(DFB)lasers.The chip occupies a total area of 0.7×1.3 mm^(2).
文摘Coal working face is damaged more and more seriously by water below the coal face floor. Therefore, floor water detection is a must in the process of extraction. This article aims to introducing application and principle of the two-gateways parallel 3-D electrical technology and the arrangement of the observation system. The authors use this method to detect the water under the floor of a mine in north of Anhui. The results show that the two-gateways parallel 3-D electrical technology can accurately locate the water-rich areas, providing the basis for drilling drainage and grouting construction.
基金Supported by China Postdoctoral Science Foundation
文摘The self-reinforced Si<sub>3</sub>N<sub>4</sub> ceramics which contain Y<sub>2</sub>O<sub>3</sub> and La<sub>2</sub>O<sub>3</sub> additives have beenprepared by hot-pressing. Under the optimum processing conditions, this material has theflexural strength of 960～1050MPa and the fracture toughness of 11.17～12.74MPa·m<sup>1/2</sup> atroom-temperature, and 720～780MPa and 22～24MPa·m<sup>1/2</sup> at 1350℃. The effects of heating rate, sintering temperature, and holding time on the microstructures and mechanical properties are investigated. The experimental results show that an appropriate β-Si<sub>3</sub>N<sub>4</sub> grainsize and homogeneous microstructure can be obtained under the conditions of a heating rate of 10℃/min, sintering temperature of 1800℃, and holding time of 1h, which are advantageous to enhancing the mechanical properties. Crack deflection in large rodlike β-Si<sub>3</sub>N<sub>4</sub> grains is a principle source of toughening.
文摘The paper deals with the application of 3 -D visible technology to reservoir management. Making use of this method for expanding - spread data point in reservoir management, can discard the false and retain the true during data recording. As a result, The quality of data recording is ensured. In reservoir description, the reservoir characteristics, such as space distribution,physical change and fluid distribution may be identified by restoring palaeostructures, building - up 3-D facics tract model and 3-D fracture system model. Seismic interpretation, geologic modeling and numerical simulation are well integrated so that they can be promote reservoir performance management to develop into the intensive management pattern.
基金supported by the National High Technology Research and Development Program ("863" Program) under Grant No.2007AA10Z235
文摘The mobile multicast technology has been a research hotspot in the wireless Internet field in recent years.Quite a large part of its applications requires the reliability in a mobile environment to be equivalent to that provided by wireline links.However,the inherent features of a mobile environment,that is,high error rate of links and dynamically changing multicast members’ locations,are great difficulties for mobile multicast,let alone reliable mobile multicast.The IPv4-based reliable mobile multicast algorithms come with two different design philosophies.A part of the algorithms is to be improved for better reliability by solving existing algorithm-related problems;while other algorithms are to implement reliable mobile multicast with new function entities introduced to guarantee reliability.
