Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments...Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments are performed with single coils which suffer from severe EPI distortions which limit resolution. By constructing phased array coils for monkey MRI studies, gains in SNR and anatomical accuracy (i.e., reduction of EPI distortions) can be achieved using parallel imaging. The major challenges associated with constructing phased array coils for monkeys are the variation in head size and space constraints. Here, we apply phased array technology to a 4-channel phased array coil capable of improving the resolution and image quality of full brain awake monkey fMRI and diffusion MRI experiments. The phased array coil is that can adapt to different rhesus monkey head sizes (ages 4-8) and fits in the limited space provided by monkey stereotactic equipment and provides SNR gains in primary visual cortex and anatomical accuracy in conjunction with parallel imaging and improves resolution in fMRI experiments by a factor of 2 (1.25 mm to 1.0 mm isotropic) and diffusion MRI experiments by a factor of 4 (1.5 mm to 0.9 mm isotropic).展开更多
Using the quantitative error probability density method we studied the S/N ratio of alternately sampled signals digitized by a 4-channel A/D. A complete expression for the S/N ratio of a 4-channel A/D non-uniform samp...Using the quantitative error probability density method we studied the S/N ratio of alternately sampled signals digitized by a 4-channel A/D. A complete expression for the S/N ratio of a 4-channel A/D non-uniform sampling signal was deduced. First we obtained an expression for the S/N ratio of a 1-channel A/D uniform sampling signal when the sampling frequency was equal to or greater than 2 times the frequency of the sampled signal. Based on the S/N ratio of a 2-channel A/D,alternating,non-uniform sampling signal,we analyzed the distribution of quantitative error using the quantitative error probability density method and the distribution convolution formula. From this the S/N ratio expression of a 4-channel A/D sampling signal was deduced. The simulation result shows that the deduced expression is correct.展开更多
A portable 4-channel electrochemical noise(EN) test system with high precision was developed.The modular instrument cRIO was used as its core and the signal conditioning module included zero resistance ammeter(ZRA),fl...A portable 4-channel electrochemical noise(EN) test system with high precision was developed.The modular instrument cRIO was used as its core and the signal conditioning module included zero resistance ammeter(ZRA),fly line,screening box and shielded wire.The EN data were acquired from two Q235 carbon steel specimens placed in 0.5 mol/L H2SO4 solution and 0.1 mol/L NaCl solution.The experimental result shows that this system can achieve an accuracy of 10 pA and 10 μV,and it can be applied to on-site multi-channel EN test.展开更多
文摘Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments are performed with single coils which suffer from severe EPI distortions which limit resolution. By constructing phased array coils for monkey MRI studies, gains in SNR and anatomical accuracy (i.e., reduction of EPI distortions) can be achieved using parallel imaging. The major challenges associated with constructing phased array coils for monkeys are the variation in head size and space constraints. Here, we apply phased array technology to a 4-channel phased array coil capable of improving the resolution and image quality of full brain awake monkey fMRI and diffusion MRI experiments. The phased array coil is that can adapt to different rhesus monkey head sizes (ages 4-8) and fits in the limited space provided by monkey stereotactic equipment and provides SNR gains in primary visual cortex and anatomical accuracy in conjunction with parallel imaging and improves resolution in fMRI experiments by a factor of 2 (1.25 mm to 1.0 mm isotropic) and diffusion MRI experiments by a factor of 4 (1.5 mm to 0.9 mm isotropic).
基金Projects 07KJZ11 supported by the President Fund of Xuzhou Medical School07KJB310117 by the Education Department of Jiangsu Province
文摘Using the quantitative error probability density method we studied the S/N ratio of alternately sampled signals digitized by a 4-channel A/D. A complete expression for the S/N ratio of a 4-channel A/D non-uniform sampling signal was deduced. First we obtained an expression for the S/N ratio of a 1-channel A/D uniform sampling signal when the sampling frequency was equal to or greater than 2 times the frequency of the sampled signal. Based on the S/N ratio of a 2-channel A/D,alternating,non-uniform sampling signal,we analyzed the distribution of quantitative error using the quantitative error probability density method and the distribution convolution formula. From this the S/N ratio expression of a 4-channel A/D sampling signal was deduced. The simulation result shows that the deduced expression is correct.
基金Supported by the National Basic Research Program of China("973"Program,No.2011CB610505)National Natural Science Foundation of China(No.61240038)
文摘A portable 4-channel electrochemical noise(EN) test system with high precision was developed.The modular instrument cRIO was used as its core and the signal conditioning module included zero resistance ammeter(ZRA),fly line,screening box and shielded wire.The EN data were acquired from two Q235 carbon steel specimens placed in 0.5 mol/L H2SO4 solution and 0.1 mol/L NaCl solution.The experimental result shows that this system can achieve an accuracy of 10 pA and 10 μV,and it can be applied to on-site multi-channel EN test.
