The diastereo-and enantioselective tandem cycloisomerization/[4+2]-cycloaddition reaction of cyclopropyl tethered allenyl ketones withα,β-unsaturated carbonyl compounds was realized firstly under mild reaction condi...The diastereo-and enantioselective tandem cycloisomerization/[4+2]-cycloaddition reaction of cyclopropyl tethered allenyl ketones withα,β-unsaturated carbonyl compounds was realized firstly under mild reaction conditions by using bimetallic silver(I)/chiral metal-N,N′-dioxide catalysts,providing a facile and atom-economic route to enantioenriched polysubstituted furopyran derivatives with good results.Possible transition state models were proposed to explain the stereoinduction.展开更多
基金supported by the National Natural Science Foundation of China(21890723,22171189)the Fundamental Research Funds for the Central Universities(YJ201819)。
文摘The diastereo-and enantioselective tandem cycloisomerization/[4+2]-cycloaddition reaction of cyclopropyl tethered allenyl ketones withα,β-unsaturated carbonyl compounds was realized firstly under mild reaction conditions by using bimetallic silver(I)/chiral metal-N,N′-dioxide catalysts,providing a facile and atom-economic route to enantioenriched polysubstituted furopyran derivatives with good results.Possible transition state models were proposed to explain the stereoinduction.
