Epidemiology of Cardiovascular Mortality in Patients under 60 Years Old in a Cardiology Department in West Africa, Dakar-Senegal

Background: Our study aimed to examine cardiovascular mortality within the working-age population, exploring epidemiological, clinical, and paraclinical features, complications, and identifying etiological factors linked to mortality. Methods: We conducted a descriptive and analytical retrospective study from September 2019 to August 2022 at the General Hospital Idrissa POUYE in Dakar, we reviewed all the medical records of patients from 15 to 60 years old who died while admitted in the cardiology department. Data collected were socioeconomic status, clinical history, type of cardiovascular disaese, length of hospitalization, circumstances and timing of death. The data were analyzed with R. Studio version 2022.12.0 + 353 and Excel 2019, with a P-value Results: The study included 73 patients, indicating a specific mortality rate of 8.8% and a proportional mortality of 39%. Predominantly male (sex ratio 1.2), the average age was 44. Key cardiovascular risk factors identified were sedentarism (76.7%), hypertension (28.8%), and smoking (21.9%). The leading cause for consultation was dyspnea (72.6%). Notable findings included a majority of patients presenting with general condition deterioration (90%) and cardiovascular collapse upon admission (23.3%). Physical exam revealed signs of heart failure in 63%. Echocardiography showed left ventricular ejection fraction impairment (81%) and pulmonary hypertension (78%). Immediate causes of death were primarily cardiogenic shock (45.2%) and septic shock (37%). The analytical study indicates that the data most closely associated with mortality were age, socio-economic level, ischemic heart disease (p = 0.034), rheumatic valvulopathies, pulmonary embolism (p = 0.034), hypertension (HTA) (p = 0.009), smoking (p = 0.011), diabetes (p = 0.011), dyslipidemias, prolonged bedrest (p = 0.001), morbid obesity (p = 0.001), and COVID-19 infection (p = 0.017). Conclusion: The prevalence of ischemic heart diseases, pulmonary embolisms, and valvulopathies in premature mortality statistics underscores the need for enhanced cardiovascular prevention efforts.

60岁以下成年女性心理压力现状、影响因素及干预对策研究——以重庆市为例

回顾和梳理压力以及女性心理压力影响因素的相关文献,通过问卷调查对重庆市4270位60岁以下成年女性的心理压力程度进行分析,考察影响60岁以下成年女性心理压力的相关因素。通过有序Logistic回归分析发现,年龄、户籍、教育程度、年收入情况、工作时长、女性人才重视程度、对政策和制度的熟悉程度等变量显著影响着60岁以下成年女性的心理压力。研究结果显示:60岁以下成年女性中,农村户籍的女性心理压力显著高于城市户籍;年龄越大、工作时长越长,心理压力越大;受教育程度和年收入水平越高、女性人才重视程度越高、对政策和制度熟悉程度越高,心理压力越小。基于此,提出以下4条干预对策:重视低收入成年女性的心理问题;重视农村“留守中老年女性”的心理健康问题;重视企事业单位女性的心理健康问题;加强对成年女性心理健康教育、舆论引导及政策宣讲等。

近60 a中国极端天气气候事件变化趋势及2023年特征分析

对不同区域极端天气气候事件变化规律的研究,有助于提高我国防灾减灾能力和有效应对气候变化风险。利用我国均一化的2254个气象观测站逐日观测资料,分析评估近60 a和2023年我国及其各区域(未包含港澳台地区)发生的极端高温、极端低温、极端干旱、极端降水和极端台风等极端天气气候事件(简称“极端事件”)的时空特征。结果表明,1961年以来,我国极端事件总体呈下降趋势,其中1970—1990年代初下降趋势明显,1990年代后期以来增加趋势明显;极端高温事件呈显著增加趋势,进入21世纪后增加趋势更加明显;极端低温事件呈减少趋势;极端降水事件总体呈增加趋势;极端干旱事件呈下降趋势且阶段性特征明显;近60 a来受台风影响出现的极端风速和降水事件呈减少趋势,主要由极端台风风速事件减少造成,而极端台风降水事件呈缓慢上升趋势。2023年我国极端事件每站平均发生139次,比气候平均值偏多28.3%。其中,极端高温事件平均发生79次(偏多76.8%),为1961年以来历史最多年;极端低温事件平均发生20次(偏少23.8%);极端降水事件平均发生14次,极端干旱事件平均发生26次,都接近常年平均值;极端台风事件平均发生0.41次(偏多4.2%),主要以极端台风降水事件为主。2023年极端事件主要出现在西南地区、江南西部、华南西部、西北地区中部和北部、内蒙西部、京津冀等地,其中四川东部、贵州南部、甘肃西部、内蒙西部等地超过200次。极端事件增多的主要原因是极端高温事件和极端干旱事件增多。综合等级指数分析表明,极端事件高危险区域主要位于南方地区,特别是东南沿海地区,近60 a综合等级指数增加的区域主要位于西南地区到东北地区南部这个过渡带上。2023年高危险区域主要出现在西南地区和西北地区中北部。

基于MSCT容积重建技术的中国汉族男性60岁判别方法

本文应用MSCT(多层螺旋CT)容积重建技术寻找与中老年男性年龄变化相关性较好的观测点位,构建单指标及多指标联合应用的中国汉族男性60岁判别式。收集177例40~70岁中国男性盆部MSCT扫描的医学数字成像和通信(digital imaging and communication in medicine,DICOM)原始影像数据,应用OsiriXMD v13.0.0软件进行容积重建,筛选出与年龄变化高度相关的点位,进行形态学观测,构建分级标准,最后采用Fisher判别法,构建60岁判别模型。最终筛选出第五腰椎、髂嵴后部及部分骶翼三个观测点位,分别构建中国男性60岁单指标及多指标联合应用判别模型。第五腰椎、髂嵴后部及部分骶翼单指标判别率分别为80.8%、78.0%、87.0%,三个指标联合应用判别率为91.0%。研究结果证明,应用MSCT容积重建技术,通过观测第五腰椎、髂嵴后部及部分骶翼,判别中国男性60岁年龄点,具有较好的可行性及准确性,可用于相关案件的判别。

China's 60 years of industrial transformation reviewed

In China, the real industrialization and modernization process started in 1949, when the Chinese people were emancipated from the yoke of the Kuomintang and the People's Republic of China (P.R.C) was founded. However, the road of emancipation has been a bumpy one. In particular, the emancipation of the mind has often been full of twists and turns. The tremendous liberation of social productive forces originated in the emancipation of the mind, whose truth has been tested by economic development practices. In the past 60 years China has paid tremendous efforts and costs in pursuit of emancipation, and today it still needs to emancipate the mind anew. For 60 years, since the formation of P.R. C, the country has kept pursuing the emancipation of the mind while exploring ways of change in institution, strategy and policy. In the first 30 years China attempted to devise an idealistic approach of transition to the socialist planned economic system, which was characterized by continuous revolution and movement. In the second 30 years China explored a realistic approach of transition to the socialist market economic system, which is characterized by incremental reform and opening-up. For six decades industry has remained at the forefront of transformation. The emancipation of the mind and the realization of change aim to ultimately make China a strong nation with an affluent people. The purpose of the six-decade struggle in new China is to erase the stigma of "being poor and blank," secure a firm and strong foothold in the world, restore China's status as a world power and let the Chinese people enjoy the affluence and welfare of a well-off society. The central mission of this national revitalization is to realize industrialization. Therefore, industrialization has been the central theme of China's revitalization in the past 60 years. After 60 years of industrialization, hundreds of millions of Chinese people are now able to enjoy ever-increasing wealth from industrial civilization. However, still a larger proportion of China's 1.3 billion people are awaiting industrial civilization. In this sense, industrialization is not only the focus of China's socioeconomic development but also the world's largest livelihood mission. Industrial development is more of a means of enhancing people's livelihood than a means of regaining the title as a world power. This will become one of the distinctive characteristics of China's industrialization in the new stage.

瑞芬太尼结合右美托咪定对年龄≥60岁膝关节置换术患者术中控制性降压效果研究

目的研究瑞芬太尼结合右美托咪定对年龄≥60岁膝关节置换术患者术中控制性降压效果的影响。方法采用均衡、随机化原则将2021年3月至2023年2月在阜南县人民医院接受膝关节置换术治疗的104例年龄≥60岁患者划分为对照组和试验组,每组52例。术中对照组采用单一右美托咪定降压方案,而试验组采用瑞芬太尼结合右美托咪定降压方案,对比2组术中不同时间段(麻醉前、插管前、插管后、术中10 min、术中30 min、停止药3 min)的血压(收缩压、舒张压)、心率;同时,对比2组患者达到控制性降压目标时间、麻醉恢复质量。结果在插管前、插管后、术中10 min、术中30 min时刻,试验组的收缩压、舒张压、心率均低于对照组(P<0.05);试验组达到控制性降压目标时间短于对照组,其麻醉恢复质量评分高于对照组(P<0.05)。结论在年龄≥60岁膝关节置换术患者中采用瑞芬太尼结合右美托咪定,能提高控制性降压效果和麻醉恢复质量。

Ancient Counties of Thousand Years’ History:Xiuwu County

正Lurking in the rocky hills and valleys of Taihang Range in Northwest Henan Province, a mysterious mountain is covered by changeable clouds and mists almost all year round. This is how it gets its name "Yuntai Mountain", which literally means "the cradle of clouds". Roughly 1,000 years ago, on lunar Sep. 9th the Chongyang Festival, a young man topped the major summit "Evodia Summit" of the Yuntai Moutain. There he saw evodia flourishing all over the hills and valleys, and

China's Electric Power Industry over 60 Years

The year 2009 marks the 60th anniversary of the People's Republic of China.During the 60 years when the new China continuously developed and got stronger,China's power industry supplied streams of electricity for economic development and people's life,making outstanding contributions to China's growth.

Power Grid Development in 60 Years since the Foundation of P.R.C.

Foreword Since the foundation of P.R.C.,the China's power grid develops with a high rate.By now,grids in all provinces except Xinjiang,Tibet,Hainan and Taiwan are AC/DC interconnected together,forming the structure of power grid interconnection in the whole country.

近60年黑龙江省极端降水事件分布特征

文中采用泰森多边形、反距离权重、Mann-Kendall检验和小波分析法分析黑龙江省1960—2021年33个气象站逐日降水数据,系统研究了6个极端降水指数的空间分布特征、时间尺度上的趋势变化、突变性和周期性。结果表明,极端降水指数空间分布变化显著,研究区北部和南部降水量较大、西部地区降水强度较大;在0.05的置信区间内,极端降水事件突变多发生在20世纪60年代和80年代左右,且主周期变化中心为41年前后;人为因素和自然因素极大地影响着极端降水指数的变化,极端降水事件对城市化进程、自然地理因素和大尺度气候因子有一定的指示作用。

Celebrating 60 Years

On November 1, 2018, Morocco and China celebrated the 60th anni-versary of diplomatic relations. On this occasion. Aziz Mekouar.Ambassador of the Kingdom of Morocco to China, spoke to ChinAfrica on a number of topics, including trade relations between the two countries and Morocco＇s participation in the Belt and Road Initiative. An edited vetsion of the interview follows.

Zhang Quanwen and His Painting, Five Thousand Years of History

Recently,the Ezhou Municipal Government provided the funds for Zhang to mount Five Thousand Years of History,so that Chinese.people everywhere may have the chance to see and appreciate his work.

Tibet's Dramatic Changes Over the Last 60 Years

The days when Wangdu was a serf are long gone, since democratic reform in Tibet in 1959 declared the endof serfdom there. However, he won fame and was remembered as Serf Champa.

A New finding pushes back the history of flying mammals by 70 million years

Teaming up with their US coworkers, CAS paleontologists have discovered, in Ningcheng of northern China’s

A Great Undertaking Comes to Fruition——Du Yuzhou on 60 Years of China Textile

For the past 60 years, China has reached the pinnacle after going through many trials and tribulations. At this historical moment, how do we evaluate the national textile industry’s past, present, and future, and the individuals who lead it? We turn to Du Yuzhou, president of China National Textile and Apparel Council, with our questions.

A summary of China’s 60 years of financial reform and transformation

The 60 years of China’s financial development has been divided into two phases,the planned economy and reform and opening-up.During the planned economy,monetary finance policy strongly supported rapid development of the national economy,as indicated by the significantly higher growth rates in monetary and credit than in major economic indicators of the national economy.During the 30 years of reform and opening-up,China’s financial system developed at a super-normal pace,establishing relatively complete and sound financial institutions and market systems,and continuously pushing forward the process of rule of law and financial internationalization. The 60 years of development in China's financial system have embarked on a path different from the West’s.The following are the valuable experiences learned from China's financial development: 1)Consistently put development as the top priority,and promote development through reform; 2)Adhere to the general principle of financial stability,and proceed from China’s reality; 3)Promote financial development surrounding the real economy; 4)Put forward financial innovation in an appropriate manner; 5)Guard against and defuse financial risks,and adhere to the principal of gradual and orderly opening-up. Amid complex domestic and international economic and financial situations,China needs to improve its regulatory mechanism of monetary policy and its financial market system,deepen the reform of financial institutions,and improve the financial regulatory system so as to make greater achievements.

56~60周岁男性多次单采血小板献血者血常规及凝血功能评价

目的探讨56~60周岁男性多次单采血小板献血者定期捐献单采血小板对其血常规及凝血功能的影响,以便更好的指导高龄献血工作的进行。方法选取本中心2021年11月—2022年8月健康男性献血者共61例,其中单采血小板献血者51例、未捐献过单采血小板的健康全血献血者10例。单采血小板献血者均为多次单采者(近一年内捐献单采血小板>10次),多次单采者中56周岁~60周岁献血者有12例为A组,18~55周岁献血者有39例为B组;未捐献过单采血小板的健康全血献血者年龄均为56~60周岁,共10例为C组。在单采血小板采集前留取样本,检测其血常规、血栓弹力图(TEG)、凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)及纤维蛋白原(Fg)。应用SPSS26.0统计分析软件进行One-way ANOVA分析比较其差异性。结果A、B、C三组比较,Hb、Hct、PLT、MPV、PCT存在一定的差异性(P<0.05),而其他血常规指标则无明显差异性(P>0.05);A组与B组比较,红细胞、白细胞、血小板相关血常规指标均无明显差异(P>0.05);A组与C组比较,Hb、Hct显著降低,而PLT、PCT则是出现升高,两指标对比差异有统计学意义(P<0.05),其他血常规指标则无明显差异(P>0.05)。三组TEG(血栓弹力图)的R值、K值、Angle值、MA值均在正常参考范围内,且A、B、C三组之间以及A组与B组、C组比较TEG各项指标均无明显差异(P>0.05)。三组中A组与B组TT、PT、APTT均在正常参考值范围内,而Fg均出现轻微升高,C组则是TT值出现一定程度升高而其他三个指标正常;A、B、C三组间比较,TT、PT存在明显差异(P<0.05),而APTT、Fg则无明显差异;A组与B组比较,凝血相关各项指标均无明显差异(P>0.05);A组TT、PT均低于C组,且两组对比差异明显(P<0.05),而APTT、Fg则无明显差异(P>0.05)。结论56~60周岁男性单采血小板献血者定期捐献单采血小板对其血常规及凝血功能并无明显影响,但同时也应在采集过程中加强对单采者健康的监测。

The Particularity of the Development of Labor Relationship in the 70-Year History of the People’s Republic of China

The past seven decades witnesses a stage marked by"ossification-consolidation-emptiness"as regards domestic labor relationship.It is highly probable that China is to be inaugurated by the stage of"falsification"in forthcoming days.A major cause is rooted in that labor relationship is the output of economic development that would request that labor relationship chime with it.The development course of labor relationship since the founding of PRC explicitly evinces that"flexibility"might be incurred in case labor relationship fails to align with economic development and with demands of marketing competitiveness.It might even propel main bodies of labor relationship to circumvent labor laws,as is verified by prevalence of large-scaled labor dispatching,and of"labor dispatching under the disguise of outsourcing".Lawmakers thus need to further ruminate over degree of tolerance on labor legislation.

60岁以上脓毒症患者单核细胞活化标志物sCD14、sCD163与新发心功能障碍和短期预后相关

目的:探讨60岁以上脓毒症患者血清可溶性分化簇(sCD)14、sCD163水平与新发心功能障碍(SICD)和短期预后的关系。方法:选取年龄≥60岁脓毒症患者98例为脓毒症组,另选取100例健康志愿者为对照组。采用酶联免疫吸附法(ELISA)检测2组血清sCD14、sCD163水平。根据心功能情况(新发左室射血分数<50%和/或二尖瓣血流最大流速/心房收缩期二尖瓣血流最大流速比值<0.8诊断为SICD)将患者分为SICD组(59例)和非SICD组(39例)。采用多因素Logistic回归分析影响脓毒症患者继发SICD的危险因素。绘制受试者工作特征(ROC)曲线,分析血清sCD14、sCD163水平对老年脓毒症患者SICD风险及院内28 d死亡的预测价值。结果:脓毒症组患者血清sCD14、sCD163水平高于对照组(P均<0.05),且治疗后逐渐降低(P均<0.01);各时间点SICD组患者血清sCD14、sCD163水平高于非SICD组(P均<0.01)。经多因素Logistic回归分析,序贯器官衰竭评分(SOFA)、血清N末端B型利钠肽原(NT-proBNP)、sCD14、sCD163水平是脓毒症患者继发SICD的独立危险因素(P均<0.05)。经ROC曲线分析,联合检测血清sCD14、sCD163水平预测年龄≥60岁脓毒症患者SICD发生风险或院内28 d死亡的曲线下面积分别为0.920(95%CI:0.860~0.979)、0.940(95%CI:0.884~0.995),较SOFA或NT-proBNP值单独预测更优(P均<0.05)。结论:血清sCD14、sCD163水平可作为预测≥60岁脓毒症患者发生SICD的生物标志物,对于短期预后不良亦有预测价值。

上海市高境镇60岁及以上未接种新冠疫苗人群的评估和动员效果调查

目的 :探讨提升老年人新型冠状病毒疫苗接种率的应对措施。方法 :于2022年6—7月期间,选取由上海市宝山区高境镇社区卫生服务中心家庭医生上门进行评估动员的516名社区居民作为研究对象,将其中由签约家庭医生进行评估和动员的236名居民作为调查组,将其余未由签约家庭医生进行评估和动员的280名居民作为对照组,收集两组居民的性别、年龄、既往疾病史、评估与动员结果等信息,进行汇总分析。结果 :516名社区居民中,无新型冠状病毒疫苗接种禁忌证,建议接种者274名(53.1%),调查组与对照组居民的新型冠状病毒疫苗接种评估结果差异具有统计学意义(P <0.05)。516名社区居民中,调查组无禁忌证、同意接种新型冠状病毒疫苗的为75名(31.8%),对照组无禁忌证、同意接种新型冠状病毒疫苗的为47名(16.8%),调查组与对照组居民的新型冠状病毒疫苗接种动员结果差异具有统计学意义(P <0.05)。结论 :对于适宜接种人群,签约家庭医生应及时提供专业建议,以提升老年人及家属对接种新型冠状病毒疫苗的安全性及必要性认知,同时安排签约家庭医生参与自己所负责辖区老年居民的接种评估和动员工作,并通过电话、微信、视频等方式灵活高效地开展评估和动员。