4'-甲基-7-(2-羟基-3-异丙胺基丙氧基)黄酮盐酸盐(SIPI-549)对乌头碱诱发的大鼠心律失常有预防作用,对氯化钡诱发的家兔心律失常有治疗作用,对哇巴因诱发的豚鼠心律失常则无明显作用。抗心律失常作用比普萘洛尔强,但比胺碘酮弱。对...4'-甲基-7-(2-羟基-3-异丙胺基丙氧基)黄酮盐酸盐(SIPI-549)对乌头碱诱发的大鼠心律失常有预防作用,对氯化钡诱发的家兔心律失常有治疗作用,对哇巴因诱发的豚鼠心律失常则无明显作用。抗心律失常作用比普萘洛尔强,但比胺碘酮弱。对狗急性心肌梗塞后24 h 的心律失常,本品的抗心律失常作用比利多卡因弱,但负性频率作用比其为强。展开更多
From the ethanol extract of Selaginella moellendorffii Hieron., a new flavone O-glycoside and three known flavone C-glycosides have been isolated and identified as 5-carboxymethyl-4′-hydroxyflavone-7-O-β-D-glucopyra...From the ethanol extract of Selaginella moellendorffii Hieron., a new flavone O-glycoside and three known flavone C-glycosides have been isolated and identified as 5-carboxymethyl-4′-hydroxyflavone-7-O-β-D-glucopyranoside 1, 6,8-di-C-β-D-glueopyranosylapigenin 2, 6-C-[3-D-glucopyranosyl-8-C-β-D-xylopyranosyl apigenin 3, 6-C-B-D-xylopyranosyl-8-C-β-glucopyranosylapigenin 4, respectively. Their structures were elucidated by spectroscopic methods.展开更多
A new flavone glycoside, 5,8-dihydroxy-4',6,7-trimethoxyflavone 8-O-(-D-glucopyranoside 1, together with three known flavonoids, pedalitin 2, cirsimartin 3 and genkwanin 4, were isolated from the aerial parts of I...A new flavone glycoside, 5,8-dihydroxy-4',6,7-trimethoxyflavone 8-O-(-D-glucopyranoside 1, together with three known flavonoids, pedalitin 2, cirsimartin 3 and genkwanin 4, were isolated from the aerial parts of Isodon enanderianus. Their structures were determined on the basis of spectral data.展开更多
Objective To study the constituents in Melicope pteleifolia.Methods Plant material was isolated with 80% EtOH.Compounds were separated with chromatographic methods and their structures were elucidated on the basis of ...Objective To study the constituents in Melicope pteleifolia.Methods Plant material was isolated with 80% EtOH.Compounds were separated with chromatographic methods and their structures were elucidated on the basis of spectral analysis(EI-MS,1H-NMR,and 13C-NMR) and chemical evidence.Results Five compounds were isolated from petrol ether or ethyl acetate soluble fraction.Their structures were identified as 3,5,3’-trihydroxy-4’-methoxy-7-(3-methylbut-2-enyloxy) flavone(pteleifolosin C,1),3,7-dimethoxyl kaempferol(kamatakenin,2),vanillic acid(3),tricosanoic acid tetradecyl ester(4),and β-sitosterol(5),respectively.Conclusion Compound 1 is a new structure named pteleifolosin C.Compounds 2-4 are isolated from this plant for the first time.展开更多
文摘4'-甲基-7-(2-羟基-3-异丙胺基丙氧基)黄酮盐酸盐(SIPI-549)对乌头碱诱发的大鼠心律失常有预防作用,对氯化钡诱发的家兔心律失常有治疗作用,对哇巴因诱发的豚鼠心律失常则无明显作用。抗心律失常作用比普萘洛尔强,但比胺碘酮弱。对狗急性心肌梗塞后24 h 的心律失常,本品的抗心律失常作用比利多卡因弱,但负性频率作用比其为强。
基金supported by the National Natural Science Foundation of China (No.30470193).
文摘From the ethanol extract of Selaginella moellendorffii Hieron., a new flavone O-glycoside and three known flavone C-glycosides have been isolated and identified as 5-carboxymethyl-4′-hydroxyflavone-7-O-β-D-glucopyranoside 1, 6,8-di-C-β-D-glueopyranosylapigenin 2, 6-C-[3-D-glucopyranosyl-8-C-β-D-xylopyranosyl apigenin 3, 6-C-B-D-xylopyranosyl-8-C-β-glucopyranosylapigenin 4, respectively. Their structures were elucidated by spectroscopic methods.
文摘A new flavone glycoside, 5,8-dihydroxy-4',6,7-trimethoxyflavone 8-O-(-D-glucopyranoside 1, together with three known flavonoids, pedalitin 2, cirsimartin 3 and genkwanin 4, were isolated from the aerial parts of Isodon enanderianus. Their structures were determined on the basis of spectral data.
文摘Objective To study the constituents in Melicope pteleifolia.Methods Plant material was isolated with 80% EtOH.Compounds were separated with chromatographic methods and their structures were elucidated on the basis of spectral analysis(EI-MS,1H-NMR,and 13C-NMR) and chemical evidence.Results Five compounds were isolated from petrol ether or ethyl acetate soluble fraction.Their structures were identified as 3,5,3’-trihydroxy-4’-methoxy-7-(3-methylbut-2-enyloxy) flavone(pteleifolosin C,1),3,7-dimethoxyl kaempferol(kamatakenin,2),vanillic acid(3),tricosanoic acid tetradecyl ester(4),and β-sitosterol(5),respectively.Conclusion Compound 1 is a new structure named pteleifolosin C.Compounds 2-4 are isolated from this plant for the first time.
