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苏木心材中一个新黄酮类化合物 被引量:2
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作者 舒诗会 韩景兰 +1 位作者 杜冠华 秦海林 《中国中药杂志》 CAS CSCD 北大核心 2008年第8期903-905,共3页
目的:从苏木Caesalpinia sappan中寻找新的活性成分。方法:用溶剂萃取及硅胶正相色谱进行活性成分的分离纯化,根据理化性质、光谱数据进行结构鉴定。结果:从苏木95%乙醇提取物中分离得到了9个化合物:3,8-dihydroxy-4,10-dimethoxy-7-oxo... 目的:从苏木Caesalpinia sappan中寻找新的活性成分。方法:用溶剂萃取及硅胶正相色谱进行活性成分的分离纯化,根据理化性质、光谱数据进行结构鉴定。结果:从苏木95%乙醇提取物中分离得到了9个化合物:3,8-dihydroxy-4,10-dimethoxy-7-oxo-[2]benzopyrano[4,3-b][1]benzopyran-7-(5H)-one(1),3-deoxysappanchal-cone(2),sappanchalcone(3),3-deoxysappanone B(4),鼠李素(rhamnetin,5),原苏木素C(protosappanin C,6),3,7-di-hydroxy-chroman-4-one(7),己二酸二甲酯(8),胡萝卜苷(daucosterin,9)。结论:化合物1为新化合物,化合物7,8为首次从该植物中分离得到。药理筛选结果表明,化合物3对多种癌细胞株具有一定的抑制活性。 展开更多
关键词 苏木 黄酮 3 8-dihydroxy-4 benzopyrano[4 benzopyran-7-(5H)-one 细胞毒活性
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A New Chromone Derivative from Stellera chamaejasme L 被引量:6
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作者 Bao Min FENG Yue Hu PEI Hui Ming HUA 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第8期738-739,共2页
A new chromone derivative, 3-[1- (2, 4, 6-trihydroxyphenyl) 3-di-(4-hydroxyphenyl) 1-propanone-2-yl] 5,7-dihydroxy-8-di(4-hydroxyphenyl)methyl-4H-1-benzopyran-4-one, named as isomohsenone was isolated from the roots o... A new chromone derivative, 3-[1- (2, 4, 6-trihydroxyphenyl) 3-di-(4-hydroxyphenyl) 1-propanone-2-yl] 5,7-dihydroxy-8-di(4-hydroxyphenyl)methyl-4H-1-benzopyran-4-one, named as isomohsenone was isolated from the roots of Stellera chamaejasme L. together with known chamaechromone. Its structure was determined by the analysis of MS and NMR data, especially 2D NMR spectra. 展开更多
关键词 Stellera chamaejasme L. CHROMONE 3-[1- (2 4 6-trihydroxyphenyl) 3-di-(4-hydroxy- phenyl)-1-propanone-2-yl] 5 7-dihydroxy-8-di-(4-hydroxyphenyl) methyl-4H-1- benzopyran-4- one.
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A New Flavone Glycoside from Isodon enanderianus
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作者 Zhi NA Shuang Xi MEI +2 位作者 Chao Ming LI Zhong Wen LIN Han Dong SUN 《Chinese Chemical Letters》 SCIE CAS CSCD 2001年第3期233-234,共2页
A new flavone glycoside, 5,8-dihydroxy-4',6,7-trimethoxyflavone 8-O-(-D-glucopyranoside 1, together with three known flavonoids, pedalitin 2, cirsimartin 3 and genkwanin 4, were isolated from the aerial parts of I... A new flavone glycoside, 5,8-dihydroxy-4',6,7-trimethoxyflavone 8-O-(-D-glucopyranoside 1, together with three known flavonoids, pedalitin 2, cirsimartin 3 and genkwanin 4, were isolated from the aerial parts of Isodon enanderianus. Their structures were determined on the basis of spectral data. 展开更多
关键词 Isodon enanderianus flavonoid flavone glycoside 5 8-dihydroxy-4’ 6 7-trimethoxyflavone 8-O-(-D-glucopyranoside.
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Phytochemical Tests, Assessment of Antioxidant Properties and Isolation of Two Compounds of Ethyl Acetate Extract of Chadian Propolis: Case of Bebotho (Southern Chad)
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作者 Salomon Madjitoloum Betoloum Abel Mbaiogaoun +1 位作者 Severin Mbaihougadobe Emmanuel Talla 《American Journal of Analytical Chemistry》 CAS 2022年第7期241-254,共14页
The present work deals with the research of chemical constituents and evaluation of antioxidant properties of Bebotho propolis. From the ethyl acetate extract, we isolated, using various chromatographic techniques, a ... The present work deals with the research of chemical constituents and evaluation of antioxidant properties of Bebotho propolis. From the ethyl acetate extract, we isolated, using various chromatographic techniques, a mixture of two identical compounds (isomers) indexed PBy4a and PByb. The structures of these compounds were elucidated by means of spectroscopic analysis techniques (MS, IR, <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, HMBC and HSQC) and by comparison of the spectral data with those described in the literature. Thus, these compounds were identified to a mixture of two chromones namely 5,7-dihydroxy-2-methylchromone-6-C-α-D-glucopyranoside and 5,7-dihydroxy-2-methylchromone-8-C-β-D-glucopyranoside, first reported in propolis. The study of the antiradical power, chelating power and the quantification of phenolic compound of these same extracts, showed interesting properties that propolis extracts have to scavenge free radicals. 展开更多
关键词 ISOLATION PROPOLIS Chelating Power 5 7-dihydroxy-2-Methylchromone-6-C-α-D-Glucopyranoside and 5 7-dihydroxy-2-Methylchromone-8-C-β-D-Glucopyranoside
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雷山石杉的化学成分研究 被引量:2
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作者 李齐激 王冲 +3 位作者 李继新 张敬杰 刘亚华 潘炉台 《中国药学杂志》 CAS CSCD 北大核心 2014年第7期550-553,共4页
目的研究雷山石杉的化学成分。方法使用制备薄层、硅胶柱色谱、SephadexLH-20及半制备高效液相色谱法等手段进行分离、纯化,结合文献资料、理化性质、1H—NMR及13C-NMR数据进行结构鉴定。结果分离得到10个化合物,分别鉴定为(15R)-12... 目的研究雷山石杉的化学成分。方法使用制备薄层、硅胶柱色谱、SephadexLH-20及半制备高效液相色谱法等手段进行分离、纯化,结合文献资料、理化性质、1H—NMR及13C-NMR数据进行结构鉴定。结果分离得到10个化合物,分别鉴定为(15R)-12,16-epoxy-11,14-dihydroxy-8,11,13-abietatrien-7-one(Ⅰ),21-epi—serratenediol-3,21-acetate(Ⅱ),setTatene—diol-3-acetate(Ⅲ),21-epi—serratenediol-3-acetate(Ⅳ),21a—hydroxy—serrat-14-en-3β-ol(Ⅴ),21β-hydroxy—serrat-14-en-3β-ol(Ⅵ),石杉碱甲(huperzineA,Ⅶ),蔗糖(Ⅷ),β-谷甾醇(Ⅸ),胡萝卜串(Ⅹ)。结论化合物Ⅰ~Ⅹ均首次从该植物中分离到。 展开更多
关键词 雷山石杉 化学成分 (15R)-12 16-epoxy—11 14-dihydroxy-8 11 13-abietatrien-7-one 21-epi—serratenediol-3 21-acetate serratene-diol-3-acetate
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