An experimental study on the current shot noise of a quantum point contact with short channel length is reported. The experimentally measured maximum energy level spacing between the ground and the first excited state...An experimental study on the current shot noise of a quantum point contact with short channel length is reported. The experimentally measured maximum energy level spacing between the ground and the first excited state of the device reached up to 7.5meV, probably due to the hard wall confinement by using shallow electron gas and sharp point contact geometry. The two-dimensionM non-equilibrium shot noise contour map shows noise suppression characteristics in a wide range of bias voltage. Fano factor analysis indicates spin-polarized transport through a short quantum point contact.展开更多
Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed...Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.展开更多
Objectives Tumor necrosis factor-α (TNF-α) may play an important role in host's immune response to mycobacterium tuberculosis (M. tuberculosis) infection. This study was to investigate the association of TNF-α...Objectives Tumor necrosis factor-α (TNF-α) may play an important role in host's immune response to mycobacterium tuberculosis (M. tuberculosis) infection. This study was to investigate the association of TNF-α gene polymorphism with pulmonary tuberculosis (TB) among patients with coal worker's pneumoconiosis (CWP). Methods A case-control study was conducted in 113 patients with confirmed CWP complicated with pulmonary TB and 113 non-TB controls with CWP. They were matched in gender, age, job, and stage of pneumoconiosis. All participants were interviewed with questionnaires and their blood specimens were collected for genetic determination with informed consent. The TNF-α gene polymorphism was determined with polymerase chain reaction of restriction fragment length polymorphism (PCR-RFLP). Frequency of genotypes was assessed for Hardy-Weinberg equilibrium by chi-square test or Fisher's exact probability. Factors influencing the association of individual susceptibility with pulmonary TB were evaluated with logistic regression analysis. Gene-environment interaction was evaluated by a multiplieative model with combined OR. All data were analyzed using SAS version 8.2 software. Results No significant difference in frequency of the TNF-α-308 genotype was found between CWP complicated with pulmonary TB and non-TB controls (2,2=5.44, P=-0.07). But difference in frequency of the TNF-α-308 A allele was identified between them (2,2-5.14, P=0.02). No significant difference in frequencies of the TNF-α-238 genotype and allele (P=0.23 and P=0.09, respectively) was found between cases and controls either, with combined (GG and AA) OR of 3.96 (95% confidence interval of 1.30-12.09) at the -308 locus of the TNF-α gene, as compared to combination of the TNF-α-238 GG and TNF-α-308 GG genotypes. Multivariate-adjusted odds ratio of the TNF-α-238 GG and TNF-α-308 GA genotypes was 1.98 (95% CI of 1.06-3.71) for risk for pulmonary TB in patients with CWP. There was a synergic interaction between the TNF-a-308 GG genotype and body mass index (OR=4.92), as well as an interaction between the TNF-α-308 GG genotype and history of BCG immunization or history of TB exposure. And, the interaction of the TNF-α-238 GG genotype and history of BCG immunization or TB exposure with risk for pulmonary TB in them was also indicated. Conclusions TNF-α-308 A allele is associated with an elevated risk for pulmonary TB, whereas TNF-α-238 A allele was otherwise.展开更多
Shot peening is a widely used surface treatment method by generating compressive residual stress near the surface of metallic materials to increase fatigue life and re- sistance to corrosion fatigue, cracking, etc. Co...Shot peening is a widely used surface treatment method by generating compressive residual stress near the surface of metallic materials to increase fatigue life and re- sistance to corrosion fatigue, cracking, etc. Compressive re- sidual stress and dent profile are important factors to eval- uate the effectiveness of shot peening process. In this pa- per, the influence of dimensionless parameters on maximum compressive residual stress and maximum depth of the dent were investigated. Firstly, dimensionless relations of pro- cessing parameters that affect the maximum compressive residual stress and the maximum depth of the dent were de- duced by dimensional analysis method. Secondly, the in- fluence of each dimensionless parameter on dimensionless variables was investigated by the finite element method. Fur- thermore, related empirical formulas were given for each di- mensionless parameter based on the simulation results. Fi- nally, comparison was made and good agreement was found between the simulation results and the empirical formula, which shows that a useful approach is provided in this pa- per for analyzing the influence of each individual parameter.展开更多
We chose a series of isoindigo-based conjugated polymer(ⅡDDT,ⅡDDT-C3 and ⅡDDT-C4) with different length of side chains and bifurcation positions to investigate the relationship between the degree of alignment and...We chose a series of isoindigo-based conjugated polymer(ⅡDDT,ⅡDDT-C3 and ⅡDDT-C4) with different length of side chains and bifurcation positions to investigate the relationship between the degree of alignment and the length of side chains and bifurcation positions.We found that the dichroic ratio was increased from 2.37 to 5.23 when the side chain was longer and the bifurcation position was away from the backbone.The π-π stacking distance was decreased from 3.67 A to 3.61 A when the bifurcation position was away from the backbone because of its smaller hindrance and the d-spacing of the(100)was increased from 20.06 A to 25.21 A when the side chain was longer.All the polymers were adopted an edge-on orientation with the backbone paralleled with the long axis of fibers.The weak interaction of side-chain in ⅡDDT-C4 was beneficial for the molecules being rearranged in parallel during the contact line receding and the strong n-n interaction could accelerate the interchain assembly of the parallel molecules through π-π interaction to form aligned fibers.展开更多
基金Supported by the Basic Science Research Program through the National Research Foundation of Korea under Grant No 2011-0004949
文摘An experimental study on the current shot noise of a quantum point contact with short channel length is reported. The experimentally measured maximum energy level spacing between the ground and the first excited state of the device reached up to 7.5meV, probably due to the hard wall confinement by using shallow electron gas and sharp point contact geometry. The two-dimensionM non-equilibrium shot noise contour map shows noise suppression characteristics in a wide range of bias voltage. Fano factor analysis indicates spin-polarized transport through a short quantum point contact.
文摘Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.
基金supported by grants from China National Programs for Science and Technology Development (Grant No. 2003BA712A11-24)Scientific Research Fund of North China Coal Medical College (Grant No. 2005-14)
文摘Objectives Tumor necrosis factor-α (TNF-α) may play an important role in host's immune response to mycobacterium tuberculosis (M. tuberculosis) infection. This study was to investigate the association of TNF-α gene polymorphism with pulmonary tuberculosis (TB) among patients with coal worker's pneumoconiosis (CWP). Methods A case-control study was conducted in 113 patients with confirmed CWP complicated with pulmonary TB and 113 non-TB controls with CWP. They were matched in gender, age, job, and stage of pneumoconiosis. All participants were interviewed with questionnaires and their blood specimens were collected for genetic determination with informed consent. The TNF-α gene polymorphism was determined with polymerase chain reaction of restriction fragment length polymorphism (PCR-RFLP). Frequency of genotypes was assessed for Hardy-Weinberg equilibrium by chi-square test or Fisher's exact probability. Factors influencing the association of individual susceptibility with pulmonary TB were evaluated with logistic regression analysis. Gene-environment interaction was evaluated by a multiplieative model with combined OR. All data were analyzed using SAS version 8.2 software. Results No significant difference in frequency of the TNF-α-308 genotype was found between CWP complicated with pulmonary TB and non-TB controls (2,2=5.44, P=-0.07). But difference in frequency of the TNF-α-308 A allele was identified between them (2,2-5.14, P=0.02). No significant difference in frequencies of the TNF-α-238 genotype and allele (P=0.23 and P=0.09, respectively) was found between cases and controls either, with combined (GG and AA) OR of 3.96 (95% confidence interval of 1.30-12.09) at the -308 locus of the TNF-α gene, as compared to combination of the TNF-α-238 GG and TNF-α-308 GG genotypes. Multivariate-adjusted odds ratio of the TNF-α-238 GG and TNF-α-308 GA genotypes was 1.98 (95% CI of 1.06-3.71) for risk for pulmonary TB in patients with CWP. There was a synergic interaction between the TNF-a-308 GG genotype and body mass index (OR=4.92), as well as an interaction between the TNF-α-308 GG genotype and history of BCG immunization or history of TB exposure. And, the interaction of the TNF-α-238 GG genotype and history of BCG immunization or TB exposure with risk for pulmonary TB in them was also indicated. Conclusions TNF-α-308 A allele is associated with an elevated risk for pulmonary TB, whereas TNF-α-238 A allele was otherwise.
基金supported by the National Natural Science Foun-dation of China (10972228,11002150,and 91016025)the Basic Research Equipment Project of Chinese Academy of Sciences(YZ200930)
文摘Shot peening is a widely used surface treatment method by generating compressive residual stress near the surface of metallic materials to increase fatigue life and re- sistance to corrosion fatigue, cracking, etc. Compressive re- sidual stress and dent profile are important factors to eval- uate the effectiveness of shot peening process. In this pa- per, the influence of dimensionless parameters on maximum compressive residual stress and maximum depth of the dent were investigated. Firstly, dimensionless relations of pro- cessing parameters that affect the maximum compressive residual stress and the maximum depth of the dent were de- duced by dimensional analysis method. Secondly, the in- fluence of each dimensionless parameter on dimensionless variables was investigated by the finite element method. Fur- thermore, related empirical formulas were given for each di- mensionless parameter based on the simulation results. Fi- nally, comparison was made and good agreement was found between the simulation results and the empirical formula, which shows that a useful approach is provided in this pa- per for analyzing the influence of each individual parameter.
基金supported by the National Natural Science Foundation of China (Nos. 21334006, 51577138, 21474113)the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB12020300)
文摘We chose a series of isoindigo-based conjugated polymer(ⅡDDT,ⅡDDT-C3 and ⅡDDT-C4) with different length of side chains and bifurcation positions to investigate the relationship between the degree of alignment and the length of side chains and bifurcation positions.We found that the dichroic ratio was increased from 2.37 to 5.23 when the side chain was longer and the bifurcation position was away from the backbone.The π-π stacking distance was decreased from 3.67 A to 3.61 A when the bifurcation position was away from the backbone because of its smaller hindrance and the d-spacing of the(100)was increased from 20.06 A to 25.21 A when the side chain was longer.All the polymers were adopted an edge-on orientation with the backbone paralleled with the long axis of fibers.The weak interaction of side-chain in ⅡDDT-C4 was beneficial for the molecules being rearranged in parallel during the contact line receding and the strong n-n interaction could accelerate the interchain assembly of the parallel molecules through π-π interaction to form aligned fibers.