Experimental Study on Towing Characteristics of Composite Bucket Wellhead Platform

With the rapid development of large-scale development of marginal oilfields in China,simple wellhead platforms that are simple in structure and easy to install have become an inevitable choice in the process of oilfield development.However,traditional simple wellhead platforms are often discarded after a single use.In pursuit of a more costeffective approach to developing marginal oilfields,this paper proposes a new offshore oil field development facility—an integrated bucket foundation for wellhead platform.To verify the safety of its towing behavior and obtain the dynamic response characteristics of the structure,this paper takes a bucket integrated bucket foundation for wellhead platform with a diameter of 40 m as the research object.By combining physical model tests and numerical simulations,it analyzes the static stability and dynamic response characteristics of the structure during towing,complete with the effects of the draft,wave height,wave period,and towing point height,which produce the dynamic responses of the structure under different influence factors,such as roll angle,pitch angle,heave acceleration and towing force as well as the sensibility to transport variables.The results show that the integrated bucket foundation for wellhead platform is capable of self-floating towing,and its movement is affected by the local environment,which will provide a reference for actual projects.

The influence of different types of satisfaction on loyalty on C2C online shopping platform:From the perspective of sellers and the platform

With the rise and development of major types of platforms,the competition for resources has become extremely fierce,and the market share of C2C platforms has been seriously threatened by the loss of resources.Therefore,building and maintaining buyers’satisfaction and loyalty to C2C platforms is critical to the survival and sustainability of C2C platforms in China.However,the current knowledge on how platform satisfaction and loyalty are constructed in the C2C e-commerce environment is incomplete.In this study,seller-based satisfaction and platform-based satisfaction are constructed separately.We further distinguish seller-based transaction satisfaction into economic and social satisfaction and explore their antecedents and consequences.To test our research hypotheses,we conduct a survey and collect data from a real online market(Taobao website).The results show that seller-based transaction satisfaction positively affects platform-based overall satisfaction and loyalty,and that perceived product quality,perceived assurance,and perceived price fairness all have a significant effect on economic satisfaction,whereas perceived relationship quality and perceived empathy significantly influence social satisfaction.These findings help us understand the literature related to customer satisfaction in the context of C2C in China and provide inspiration for online sellers and platforms.

Scheme of Railway 5G Integrated Innovation Test Platform

An inevitable trend has already taken shape for the application of the 5th Generation Mobile Communication Technology(5G)in the railway sector.The application scenarios and business types of the railway sector are complex and diverse,so it is indispensable to test and verify the railway 5G before actual deployment.The design and creation of the railway 5G integrated innovation test platform provides engineering design,test and verification conditions for the networking,coverage and business development of 5G public networks and 5G-R in railway scenarios.This paper introduces the design of the overall architecture for the integrated railway 5G innovation test platform according to the railway network requirements,application scenarios and intelligent development trend;respectively elaborates on the design of the 5G-R core network,bearer network and wireless access along loop tracks,in combination with the characteristics of railway scenarios and the requirements of railway dispatching,operation and safety;raises further solutions on the network deployment and coverage schemes of 5G public networks so as to meet the application requirements of 5G public networks.The study results show that the integrated railway 5G innovation test platform scheme contains co-existence of 5G public and private networks,combines the indoor and outdoor scenarios,as well as takes into account of the dynamic and static tests so as to meet the environmental requirements for the integrated railway 5G test and application of all network functions,for which it can provide comprehensive technical support for railway 5G technology research and development,standard formulation,testing,etc.

Development of a Remotely Controlled Testing Platform with Low-drag Air-ventilated Hull

This paper addresses the development and testing of a remotely controlled boat platform with an innovative air-ventilated hull. The application of air cavities on the underside of ship hulls is a promising means for reducing hydrodynamic drag and pollutant emissions and increasing marine transportation efficiency. Despite this concept＇s potential, design optimization and high-performance operation of novel air-cavity ships remain a challenging problem. Hull construction and sensor instrumentation of the model-scale air-cavity boat is described in the paper. The modular structure of the hull allows for easy modifications, and an electric propulsion unit enables self-propelled operation. The boat is controlled remotely via a radio transmission system. Results of initial tests are reported, including thrust, speed, and airflow rate in several loading conditions. The constructed platform can be used for optimizing air-cavity systems and testing other innovative hull designs. This system can be also developed into a high-performance unmanned boat.

Control system for dynamic testing platform of asymmetrical pitch mechanism

A novel asymmetrical pitch system for rotary wing is presented. The pitch control characteristics are studied and analyzed. Because elastic linkage is a key part in whole asymmetrical pitch system, in order to obtain the variation of the elastic linkage deformation, an experimental platform mainly based on the device of micro aerial vehicles （MAVs） and a new control system mounted on TMS320LF2407 are designed. This control system has its compacted configuration and reliability. Finally, using this system to control the MAV for simulating the flying forward, experimental results show the MAV＇s flight attitude can he controlled based on the variation of the elastic linkage.

Research on the Computer Software Testing Method Based on Multiple Platforms

Informationization plays an important role in modern life and production.And various software is one of the bases for it.Before it goes into service,software needs to go through many steps,including software development,design,etc.In software development,test is the key to identify and control bugs and errors in the software.Therefore,software companies often test the software to ensure that it is qualified.In recent years,more attention has been paid to a multi-platform computer software testing method,which can make up for defects in traditional testing methods to improve test accuracy.Firstly,this paper illustrates the connotation and features of software testing.Secondly,common software testing platforms and their requirements are analyzed.Finally,this paper proposes software testing method based on multiple platforms.

First Systematic Testing Platform for Pressurization Feed System Developed for Liquid Rocket Propellant in China

Beijing Aerospace System Engineering Institute of China Academy of Launch Vehicle Technology (CALT) declared recently that theinstitute has set up a laboratory whichwould operate a newly

桂东北D/C界线沉积特征及对台盆相间演化的启示

台盆相间是桂东北泥盆纪和石炭纪沉积的重要特色,而D/C界线又是台盆相间沉积最突出的一个时段之一。文章回顾并评述了桂东北D/C界线的研究历程、相序划分、主要代表剖面,认为桂东北D/C界线可划分为碎屑岩相序和碳酸盐岩相序以及它们的过渡类型。通过对20条典型剖面的岩性组合特征对比,恢复了桂东北D/C界线海平面相对下降期的岩相古地理,结果显示桂东北在该时期主要存在柳州、桂林两大台地以及多个小型台地,台地间普遍发育快速相变的台沟、盆地沉积,石炭纪初期海水变浅,台地分布范围显著扩大,江南古陆供给增强,台盆相间格局迅速发展。为了进一步探讨桂东北D/C界线的演化过程和背后的控制因素,文章分析了广西整体的台盆相间演化的阶段性、同沉积构造作用以及海平面变化的影响,梳理了台盆相间演化过程中沉积环境分异与构造运动-海平面的关系,认为在滇黔桂裂谷盆地在持续断陷发展的前提下,桂东北D/C界线沉积分异的主要原因可能是受冈瓦纳大陆冰川形成与消融导致的海平面异常波动,以及柳江运动引发的局部同沉积断陷强度差异变动影响,且构造和沉积要素在D/C界线的耦合作用达到最强,最终促进桂东北台盆相间格局在D/C界线达到鼎盛。在此模式下,可以将台盆相间的演化划分为4个阶段,早泥盆世中期—晚期为台盆相间格局的孕育期,早泥盆世晚期—中泥盆世晚期沉积开始分异,为台盆相间格局的发展期,晩泥盆世—早石炭世台-盆出现强烈分割,海平面异常下降和柳江运动同时作用于沉积,为台盆相间格局的鼎盛期,早石炭世之后,台盆相间沉积维持了一定时期的强度,晚石炭世开始海水逐步恢复正常后台盆相间逐渐减弱,为台盆相间格局的衰退期。

HBV、HCV、HIV血筛多中心研究免疫学灰区的核酸检测分析与临床特征研究

目的分析化学发光灰区标本的临床特征及核酸检测对化学发光灰区标本结果判断的指导性意义。方法收集2021年7月—12月全国不同地区的5家综合医院入院患者术前/输血前血源性传播疾病样本检测结果,对化学发光灰区检测结果的标本进行核酸检测结果及临床特征分析。结果5723例样本中总计检出HBV免疫灰区样本28例(占比0.49%),HCV灰区样本20例(占比0.35%)。经核酸检测验证,28例HBV灰区样本中,15例HBV样本核酸检测为阳性(占比53.5%),其HBcAb也均为阳性;13例HBV样本核酸检测为阴性(占比46.5%),其中HBcAb阳性4例。HBV与HCV免疫检测灰区在临床各个科室均有发现,出现HBV灰区样本最多的前三科室为骨科、妇科、泌尿科,灰区样本核酸验证假阳性最多的临床科室为妇科与骨科。HCV灰区样本最多的前三科室为泌尿、肾内、外科,且均为假阳性。HBV灰区样本患者临床诊断结果有35.7%(10/28)为肿瘤类疾病,HCV灰区样本患者临床诊断结果有40%(8/20)为肿瘤类疾病。结论化学发光法容易造成假阳性结果,应注意复检验证,且设置灰区并非必要。灰区样本可见于多个临床科室,具有一定的临床分布特征。核酸检测可以提高检测灵敏度并且更大限度保证结果的准确性,能够验证免疫检测灰区。

基于C语言的高校虚拟实验室平台研究

伴随着信息技术的迅猛进步,我国高校实验教学领域面临资源紧张、教学模式单一等挑战。为了提高实验教学品质,推动教学革新,文章设计并实现了一套基于C语言的高校虚拟实验室平台。该平台通过模拟实际实验环境,为高校学生提供了便捷且高效的实验学习体验。文章阐述了平台的设计理念、基础架构、功能模块以及实现流程,对平台性能进行了测试和优化。

超高温陶瓷改性C/C复合材料抗氧化烧蚀性能研究进展

碳/碳(C/C)复合材料具有高强、轻质和耐温等优势,在航天领域取得广泛应用;但由于其抗氧化性能较差,难以满足高超声速飞行器长时飞行、大气层再入飞行和跨大气层飞行的服役环境。利用超高温陶瓷改性C/C复合材料(C/C-UHTC)可以显著提高C/C复合材料的抗氧化烧蚀性能,有望满足新一代飞行器长时间抗氧化、抗烧蚀及结构强度的要求。本文总结了C/C-UHTC复合材料烧蚀性能的常用测试方法,包括氧-乙炔烧蚀、等离子烧蚀、激光烧蚀和风洞烧蚀,简要介绍了各种烧蚀性能测试方法的特点。此外,对近年来Zr系和Hf系单组元、双组元和三组元C/C-UHTC复合材料的烧蚀性能及烧蚀机理进行详细阐述。

Current testing strategies for hepatitis C virus infection in blood donors and the way forward

Screening tests for blood donations are based upon sensitivity, cost-effectiveness and their suitability for high-throughput testing. Enzyme immunoassay (EIAs) for hepatitis C virus (HCV) antibodies were the initial screening tests introduced. The ”first generation“ antibody EIAs detected seroconversion after unduly long infectious window period. Improved HCV antibody assays still had an infectious window period around 66 d. HCV core antigen EIAs shortened the window period considerably, but high costs did not lead to widespread acceptance. A fourth-generation HCV antigen and antibody assay (combination EIA) is more convenient as two infectious markers of HCV are detected in the same assay. Molecular testing for HCV-RNA utilizing nucleic acid amplification technology (NAT) is the most sensitive assay and shortens the window period to only 4 d. Implementation of NAT in many developed countries around the world has resulted in dramatic reductions in transfusion transmissible HCV and relative risk is now < 1 per million donations. However, HCV serology still continues to be retained as some donations are serology positive but NAT negative. In resource constrained countries HCV screening is highly variable, depending upon infrastructure, trained manpower and financial resource. Rapid tests which do not require instrumentation and are simple to perform are used in many small and remotely located blood centres. The sensitivity as compared to EIAs is less and wherever feasible HCV antibody EIAs are most frequently used screening assays. Efforts have been made to implement combined antigen-antibody assays and even NAT in some of these countries.

Site testing campaign for the Large Optical/infrared Telescope of China:general introduction of the Daocheng site

The Daocheng site is one of the three candidate sites for the Large Optical/infrared Telescope(LOT)of China.It was discovered by Yunnan Observatories during the survey of potential sites for the next-generation large-aperture solar telescopes of China.This paper describes the overview of the site,the observation platform and the monitor instrument.In addition,simple statistical results are presented(from November,2016 up to December,2017).Detailed data results can refer to the overview of LOT site testing and data analysis articles,which were published during the same period.

Recent progress on rapid diagnosis of COVID-19 by point-of-care testing platforms

The outbreak of COVID-19 has drawn great attention around the world.SARS-CoV-2 is a highly infectious virus with occult transmission by many mutations and a long incubation period.In particular,the emergence of asymptomatic infections has made the epidemic even more severe.Therefore,early diagnosis and timely management of suspected cases are essential measures to control the spread of the virus.Developing simple,portable,and accurate diagnostic techniques for SARS-CoV-2 is the key to epidemic prevention.The advantages of point-of-care testing technology make it play an increasingly important role in viral detection and screening.This review summarizes the point-of-care testing platforms developed by nucleic acid detection,immunological detection,and nanomaterial-based biosensors detection.Furthermore,this paper provides a prospect for designing future highly accurate,cheap,and convenient SARS-CoV-2 diagnostic technology.

Expi293F表达重组鲎C因子用于荧光法内毒素检测

鲎C因子是一种对痕量内毒素高度敏感的丝氨酸蛋白酶原,在医药行业可替代鲎试剂用于内毒素检测。然而其重组表达困难,且对于环境中内毒素的控制要求极高。该文首先克隆了来源于东方鲎的全长C因子,并在N末端和C末端分别添加了Flag标签和6×His标签,同时用哺乳细胞表达载体中的分泌信号肽替换掉了原始C因子信号肽。构建好的重组质粒转染至人胚胎肾脏细胞Expi293F悬浮培养7 d后收获上清液,Western Blot检测蛋白与预测大小128 kDa一致,具有与内毒素结合以及结合后切割荧光底物的能力。该研究首次在人胚胎肾脏细胞Expi293F中成功表达出具有生物学活性的全长C因子,表达量达到19.18 mg/L,比DING在昆虫细胞SF9中的表达量提高了113%。该方法对于后续开发低成本内毒素检测试剂盒具有指导意义。

Improvement of quantitative testing of liver function in patients with chronic hepatitis C after installment of antiviral therapy

MM： To investigate if and to what extent antiviral therapy influenced a broad panel of quantitative testing of liver function （QTLF）. METHODS： Fifty patients with chronic hepatitis C were either treated with interferon （n = 8）, interferon/ribavirin （n = 19） or peg-interferon/ribavirin （n = 23）. Quantitative testing of liver function, including aminopyrine breath test （ABT）, galactose elimination capacity （GEC）, sorbitol clearance （SCI） and indocyanine green clearance （ICG） was performed before and 3 mo after initiation of antiviral therapy. RESULTS： After 3 mo of antiviral treatment, 36 patients showed normal transaminases and were negative for HCVRNA, 14 patients did not respond to therapy. ABT and GEC as parameters of microsomal and cytosolic liver function were reduced in all patients before therapy initiation and returned to normal values in the 36 therapy responders after 3 too. Parameters of liver perfusion （SCl and ICG） were not affected by antiviral therapy. In the 14 non-responders, no changes in QTLF values were observed during the treatment period. CONCLUSION： ICG and SCI remained unaffected in patients with chronic hepatitis C, while ABT and GEC were significantly compromised. ABT and GEC normalized in responders to antiviral therapy. Early determination of ABT and GEC may differentiate responders from non-responders to antiviral treatment in hepatitis C.

Application of the monitoring and early warning system for internal solitary waves:Take the second natural gas hydrates production test in the South China Sea as an example

Internal solitary waves(ISWs) contain great energy and have the characteristics of emergency and concealment. To avoid their damage to offshore engineering, a new generation of monitoring and early warning system for ISWs was developed using technologies of double buoys monitoring, intelligent realtime data transmission, and automatic software identification. The system was applied to the second natural gas hydrates(NGHs) production test in the Shenhu Area, South China Sea(SCS) and successfully provided the early warning of ISWs for 173 days(from October 2019 to April 2020). The abrupt changes in the thrust force of the drilling platform under the attack of ISWs were consistent with the early warning information, proving the reliability of this system. A total of 93 ISWs were detected around the drilling platform. Most of them occurred during the spring tides in October–December 2019 and April 2020, while few of them occurred in winter. As suggested by the theoretical model, the full-depth structure of ISWs was a typical current profile of mode-1, and the velocities of wave-induced currents can reach 80 cm/s and30 cm/s, respectively, in the upper ocean and near the seabed. The ISWs may be primarily generated from the interactions between the topography and semidiurnal tides in the Luzon Strait, and then propagate westward to the drilling platform. This study could serve as an important reference for the early warning of ISWs for offshore engineering construction in the future.

Predictive potential of IL-28B genetic testing for interferon based hepatitis C virus therapy in Pakistan: Current scenario and future perspective

In Pakistan which ranked second in terms of hepatitis C virus(HCV) infection, it is highly needed to have an established diagnostic test for antiviral therapy responseprediction. Interleukin 28B(IL-28B) genetic testing is widely used throughout the world for interferon based therapy prediction for HCV patients and is quite helpful not only for health care workers but also for the patients. There is a strong relationship between single nucleotide polymorphisms at or near the IL-28 B gene and the sustained virological response with pegylated interferon plus ribavirin treatment for chronic hepatitis C. Pakistan is a resource limited country, with very low per capita income and there is no proper social security(health insurance) system. The allocated health budget by the government is very low and is used on other health emergencies like polio virus and dengue virus infection. Therefore it is proposed that there should be a well established diagnostic test on the basis of IL-28 B which can predict the antiviral therapy response to strengthen health care set-up of Pakistan. This test once established will help in better management of HCV infected patients.

体外膜氧合联合介入取栓救治蛋白C基因突变所致高危肺栓塞一例

遗传性蛋白C缺陷症是由蛋白C基因突变引起的一种染色体遗传病,可导致静脉血栓形成,多与外显子4~9和内含子8的突变有关。蛋白C基因突变引起的致死性肺栓塞罕见,治疗面临巨大挑战。本文报道1例由蛋白C基因8号外显子移码突变引起的致死性肺栓塞,采用体外膜氧合进行呼吸、循环支持,并成功实行介入取栓的救治经验,为该疾病的诊断及救治提供参考。

Ni/c-BN对激光熔覆316L不锈钢熔覆层组织与耐蚀性的影响

采用激光熔覆技术在马氏体不锈钢(ZG06Cr13Ni4Mo)表面制备了Ni/c-BN增强316L不锈钢复合熔覆层。通过XRD、SEM、EDS、电化学试验和冲蚀试验分析了不同Ni/c-BN含量对熔覆层的显微组织和和耐蚀性影响。结果表明,复合熔覆层的物相由FeCr_(0.29)Ni_(0.16)C_(0.06)固溶体组成,随着Ni/c-BN添加量的增加,其顶部组织的等轴晶数量减少,胞状树枝晶的数量增多。复合熔覆层的耐蚀性随Ni/c-BN添加量的增加呈先升高后降低的趋势,当Ni/c-BN添加量为5wt.%时,熔覆层的耐蚀性最好。过量的Ni/c-BN使得熔覆层表面存在气孔,且导致熔覆层内部存在少量大尺寸残留c-BN,降低了熔覆层的耐腐蚀性和耐冲蚀性。