Platinum(Pt)-based noble metal catalysts(PGMs)are the most widely used commercial catalysts,but they have the problems of high cost,low reserves,and susceptibility to small-molecule toxicity.Transition metal oxides(TM...Platinum(Pt)-based noble metal catalysts(PGMs)are the most widely used commercial catalysts,but they have the problems of high cost,low reserves,and susceptibility to small-molecule toxicity.Transition metal oxides(TMOs)are regarded as potential substitutes for PGMs because of their stability in oxidizing environments and excellent catalytic performance.In this study,comprehensive investigation into the influence of elastic strains on the adsorption energies of carbon(C),hydrogen(H)and oxygen(O)on TMOs was conducted.Based on density functional theory(DFT)calculations,these effects in both tetragonal structures(PtO_(2),PdO_(2))and hexagonal structures(ZnO,CdO),along with their respective transition metals were systematically explored.It was identified that the optimal adsorption sites on metal oxides pinpointed the top of oxygen or the top of metal atom,while face-centered cubic(FCC)and hexagonal close-packed(HCP)holes were preferred for the transition metals.Furthermore,under the influence of elastic strains,the results demonstrated significant disparities in the adsorption energies of H and O between oxides and transition metals.Despite these differences,the effect of elastic strains on the adsorption energies of C,H and O on TMOs mirrored those on transition metals:adsorption energies increased under compressive strains,indicating weaker adsorption,and decreased under tension strains,indicating stronger adsorption.This behavior was rationalized based on the d-band model for adsorption atop a metallic atom or the p-band model for adsorption atop an oxygen atom.Consequently,elastic strains present a promising avenue for tailoring the catalytic properties of TMOs.展开更多
[Objectives]The paper was to screen effective biocontrol strains against Meloidogyne incognita.[Methods]The effect of six bacterial strains sourced from the research group s strain library on the activity of second in...[Objectives]The paper was to screen effective biocontrol strains against Meloidogyne incognita.[Methods]The effect of six bacterial strains sourced from the research group s strain library on the activity of second instar larvae of M.incognita,as well as on egg hatching,was evaluated.[Results]The treatment of fermentation supernatant derived from the X-2 strain exhibited a pronounced lethal effect on M.incognita,with a corrected mortality rate reaching 97%within 72 h.Additionally,this treatment significantly inhibited egg hatching,achieving an inhibition rate of 94.69%at a 20-fold dilution.The strain was identified as Bacillus velezensis,belonging to the genus Bacillus,and was designated as RKN1111.[Conclusions]This study presents alternative strains and a theoretical framework for the biological control of M.incognita.展开更多
Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Walle...Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary behaviors.The preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion repair.In the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis rats.Mechanical nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the hindpaws.Dorsal von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve transections.Baseline withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not sex.Withdrawal thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated rats.Following sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the injury.However,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative Control rats.Furthermore,PEG-fused rats with significantly improved Sciatic Functional Index scores at or after 4 weeks postoperatively exhibited yet-earlier von Frey filament recove ry compared with those without Sciatic Functional Index recovery,suggesting a correlation between successful PEG-fusion and both motor-dominant and sensory-dominant behavioral recoveries.This correlation was independent of the sex or strain of the rat.Furthermore,our data showed that the acceleration of von Frey filament sensory recovery to baseline was solely due to the PEG-fused sciatic nerve and not saphenous nerve collateral outgrowths.No chronic hypersensitivity developed in any rat up to 12 weeks.All these data suggest that PEG-fusion repair of transection peripheral nerve injuries co uld have important clinical benefits.展开更多
在线、实时、准确监测舰船螺旋桨推力对船-机-桨匹配设计、舰船快速性预报及推进轴系健康管理等具有重要意义。然而,受轴系振动及环境干扰等测量噪声影响,螺旋桨推力产生的微弱应变信号易被测量噪声淹没,导致难以准确测量推力。当前,一...在线、实时、准确监测舰船螺旋桨推力对船-机-桨匹配设计、舰船快速性预报及推进轴系健康管理等具有重要意义。然而,受轴系振动及环境干扰等测量噪声影响,螺旋桨推力产生的微弱应变信号易被测量噪声淹没,导致难以准确测量推力。当前,一些常用的信号降噪方法,比如傅里叶变换、小波分析等均是基于纯数据降噪,未考虑测量数据中潜藏的力学机制。不同于这类降噪方法,Kalman滤波可同时考虑测量数据噪声及数据中的力学机制,对目标实现最小方差无偏估计,因而有更高的估计精度。因此,本文利用Kalman滤波结合应变测量信号提出一种螺旋桨推力高精度、在线辨识方法。以恒定转速、变转速及低频波动转速3种工况为例,研究了不同信噪比下本文方法的推力辨识精度与鲁棒性。研究表明,在信噪比仅为20 d B时,推力辨识最大相对误差仅为4.85%,因此本文方法在低信噪比下仍有很高的辨识精度与鲁棒性。同时,本文提出方法属于时域辨识方法,在转速突变、螺旋桨缠绕渔网等突发工况时亦能实时跟踪推力变化,因此可用于螺旋桨推力及轴系状态的在线、实时监测。展开更多
基金Science and Technology Commission of Shanghai Municipality(21ZR1472900,22ZR1471600)。
文摘Platinum(Pt)-based noble metal catalysts(PGMs)are the most widely used commercial catalysts,but they have the problems of high cost,low reserves,and susceptibility to small-molecule toxicity.Transition metal oxides(TMOs)are regarded as potential substitutes for PGMs because of their stability in oxidizing environments and excellent catalytic performance.In this study,comprehensive investigation into the influence of elastic strains on the adsorption energies of carbon(C),hydrogen(H)and oxygen(O)on TMOs was conducted.Based on density functional theory(DFT)calculations,these effects in both tetragonal structures(PtO_(2),PdO_(2))and hexagonal structures(ZnO,CdO),along with their respective transition metals were systematically explored.It was identified that the optimal adsorption sites on metal oxides pinpointed the top of oxygen or the top of metal atom,while face-centered cubic(FCC)and hexagonal close-packed(HCP)holes were preferred for the transition metals.Furthermore,under the influence of elastic strains,the results demonstrated significant disparities in the adsorption energies of H and O between oxides and transition metals.Despite these differences,the effect of elastic strains on the adsorption energies of C,H and O on TMOs mirrored those on transition metals:adsorption energies increased under compressive strains,indicating weaker adsorption,and decreased under tension strains,indicating stronger adsorption.This behavior was rationalized based on the d-band model for adsorption atop a metallic atom or the p-band model for adsorption atop an oxygen atom.Consequently,elastic strains present a promising avenue for tailoring the catalytic properties of TMOs.
基金Supported by Key R&D Project of Science&Technology Department of Ningxia Hui Autonomous Region(2021BBF02013)Post-doctoral Program of Hebei Province(2019003011)Hebei Province Innovation Ability Enhancement Plan Project(225676109H).
文摘[Objectives]The paper was to screen effective biocontrol strains against Meloidogyne incognita.[Methods]The effect of six bacterial strains sourced from the research group s strain library on the activity of second instar larvae of M.incognita,as well as on egg hatching,was evaluated.[Results]The treatment of fermentation supernatant derived from the X-2 strain exhibited a pronounced lethal effect on M.incognita,with a corrected mortality rate reaching 97%within 72 h.Additionally,this treatment significantly inhibited egg hatching,achieving an inhibition rate of 94.69%at a 20-fold dilution.The strain was identified as Bacillus velezensis,belonging to the genus Bacillus,and was designated as RKN1111.[Conclusions]This study presents alternative strains and a theoretical framework for the biological control of M.incognita.
基金supported by DOD AFIRMⅢW81XWH-20-2-0029 subcontract,UT POC19-1774-13Neuraptive Therapeutics Inc.26-7724-56+1 种基金NIH R01-NS128086 grantsLone Star Paralysis gift(to GDB)。
文摘Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary behaviors.The preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion repair.In the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis rats.Mechanical nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the hindpaws.Dorsal von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve transections.Baseline withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not sex.Withdrawal thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated rats.Following sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the injury.However,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative Control rats.Furthermore,PEG-fused rats with significantly improved Sciatic Functional Index scores at or after 4 weeks postoperatively exhibited yet-earlier von Frey filament recove ry compared with those without Sciatic Functional Index recovery,suggesting a correlation between successful PEG-fusion and both motor-dominant and sensory-dominant behavioral recoveries.This correlation was independent of the sex or strain of the rat.Furthermore,our data showed that the acceleration of von Frey filament sensory recovery to baseline was solely due to the PEG-fused sciatic nerve and not saphenous nerve collateral outgrowths.No chronic hypersensitivity developed in any rat up to 12 weeks.All these data suggest that PEG-fusion repair of transection peripheral nerve injuries co uld have important clinical benefits.
文摘在线、实时、准确监测舰船螺旋桨推力对船-机-桨匹配设计、舰船快速性预报及推进轴系健康管理等具有重要意义。然而,受轴系振动及环境干扰等测量噪声影响,螺旋桨推力产生的微弱应变信号易被测量噪声淹没,导致难以准确测量推力。当前,一些常用的信号降噪方法,比如傅里叶变换、小波分析等均是基于纯数据降噪,未考虑测量数据中潜藏的力学机制。不同于这类降噪方法,Kalman滤波可同时考虑测量数据噪声及数据中的力学机制,对目标实现最小方差无偏估计,因而有更高的估计精度。因此,本文利用Kalman滤波结合应变测量信号提出一种螺旋桨推力高精度、在线辨识方法。以恒定转速、变转速及低频波动转速3种工况为例,研究了不同信噪比下本文方法的推力辨识精度与鲁棒性。研究表明,在信噪比仅为20 d B时,推力辨识最大相对误差仅为4.85%,因此本文方法在低信噪比下仍有很高的辨识精度与鲁棒性。同时,本文提出方法属于时域辨识方法,在转速突变、螺旋桨缠绕渔网等突发工况时亦能实时跟踪推力变化,因此可用于螺旋桨推力及轴系状态的在线、实时监测。
