目的探讨AIMS65评分在肝硬化食管胃底静脉曲张破裂出血(esophageal and gastric variceal bleeding,EGVB)患者住院死亡中的预测价值。方法回顾性纳入我院2016年1月至2020年12月诊治的378例肝硬化EGVB患者,根据住院期间生存情况分为存活...目的探讨AIMS65评分在肝硬化食管胃底静脉曲张破裂出血(esophageal and gastric variceal bleeding,EGVB)患者住院死亡中的预测价值。方法回顾性纳入我院2016年1月至2020年12月诊治的378例肝硬化EGVB患者,根据住院期间生存情况分为存活组345例(91.27%)和死亡组33例(8.73%)。通过电子病历系统收集患者入院时临床资料,采用多因素Logistic回归分析EGVB患者住院期间死亡的危险因素。采用ROC曲线分析AIMS65评分预测EGVB患者住院期间死亡的效能。结果单因素分析显示,死亡组中重度腹水、有肝性脑病的比例以及GBS评分、FRS评分、AIMS65评分均高于存活组(P<0.05),年龄、性别、高血压等与存活组比较,差异无统计学意义(P>0.05)。多因素Logistic回归分析结果显示,GBS评分(OR=1.704,95%CI:1.069~2.717,P=0.026)、FRS评分(OR=1.758,95%CI:1.160~2.663,P=0.008)、AIMS65评分(OR=1.868,95%CI:1.228~2.842,P=0.002)是肝硬化EGVB患者住院期间死亡的危险因素。ROC曲线分析显示,AIMS65评分预测EGVB患者住院期间死亡的AUC为0.836(95%CI:0.781~0.891),敏感性为72.73%,特异性为82.03%。结论AIMS65评分升高是肝硬化EGVB患者住院期间死亡的危险因素,可预测该类人群短期死亡风险。展开更多
A novel upper gastrointestinal bleeding risk stratification score(AIMS65) has recently been developed and validated. It has advantages over existing risk scores including being easy to remember and lack of subjectivit...A novel upper gastrointestinal bleeding risk stratification score(AIMS65) has recently been developed and validated. It has advantages over existing risk scores including being easy to remember and lack of subjectivity in calculation. We comment on a recent study that has cast doubt on the applicability of AIMS65 in the peptic ulcer disease population. Although promising, further studies are required to evaluate the validity of AIMS65 in various populations.展开更多
文摘目的探讨AIMS65评分在肝硬化食管胃底静脉曲张破裂出血(esophageal and gastric variceal bleeding,EGVB)患者住院死亡中的预测价值。方法回顾性纳入我院2016年1月至2020年12月诊治的378例肝硬化EGVB患者,根据住院期间生存情况分为存活组345例(91.27%)和死亡组33例(8.73%)。通过电子病历系统收集患者入院时临床资料,采用多因素Logistic回归分析EGVB患者住院期间死亡的危险因素。采用ROC曲线分析AIMS65评分预测EGVB患者住院期间死亡的效能。结果单因素分析显示,死亡组中重度腹水、有肝性脑病的比例以及GBS评分、FRS评分、AIMS65评分均高于存活组(P<0.05),年龄、性别、高血压等与存活组比较,差异无统计学意义(P>0.05)。多因素Logistic回归分析结果显示,GBS评分(OR=1.704,95%CI:1.069~2.717,P=0.026)、FRS评分(OR=1.758,95%CI:1.160~2.663,P=0.008)、AIMS65评分(OR=1.868,95%CI:1.228~2.842,P=0.002)是肝硬化EGVB患者住院期间死亡的危险因素。ROC曲线分析显示,AIMS65评分预测EGVB患者住院期间死亡的AUC为0.836(95%CI:0.781~0.891),敏感性为72.73%,特异性为82.03%。结论AIMS65评分升高是肝硬化EGVB患者住院期间死亡的危险因素,可预测该类人群短期死亡风险。
文摘A novel upper gastrointestinal bleeding risk stratification score(AIMS65) has recently been developed and validated. It has advantages over existing risk scores including being easy to remember and lack of subjectivity in calculation. We comment on a recent study that has cast doubt on the applicability of AIMS65 in the peptic ulcer disease population. Although promising, further studies are required to evaluate the validity of AIMS65 in various populations.