目的:比较分析PLo S ALMs与Altmetrics评分、单篇论文学术评价指标之间的相关性及对单篇论文的评价效度。方法:以PLo S系列期刊PLo S Biology、PLo S Medicine为例,基于PLo S ALMs论文层面计量指标数据,分析比较其阅览量、下载量、讨论...目的:比较分析PLo S ALMs与Altmetrics评分、单篇论文学术评价指标之间的相关性及对单篇论文的评价效度。方法:以PLo S系列期刊PLo S Biology、PLo S Medicine为例,基于PLo S ALMs论文层面计量指标数据,分析比较其阅览量、下载量、讨论量、保存量、被引频次、推荐量与Altmetrics评分、h指数、学术迹T之间的相关性以及对单篇论文的评价效果。结果:阅览量、下载量、讨论量与被引频次、h指数有正相关性,推荐量与h指数、学术迹无关。Altmetrics评分与阅览量、下载量和讨论量呈中度相关性,与被引频次呈弱相关。结论:PLo S ALMs是一个多维评价,应该应用多指标测度,才能体现研究成果的综合实力。展开更多
介绍了一个基于覆盖网(Overlay Network)技术的应用层组播视频直播系统,它在IPv6网络上实现,提出了用IP地址最大匹配法与时延来寻找最优父结点。系统采用代理的结构和三级的服务模型,此外本系统基于当前流行Windows Media Technology技...介绍了一个基于覆盖网(Overlay Network)技术的应用层组播视频直播系统,它在IPv6网络上实现,提出了用IP地址最大匹配法与时延来寻找最优父结点。系统采用代理的结构和三级的服务模型,此外本系统基于当前流行Windows Media Technology技术,对流媒体数据进行处理。展开更多
BACKGROUND Alström syndrome(AS,OMIM ID 203800)is a rare disease involving multiple organs in children and is mostly reported in non-Chinese patients.In the Chinese population,there are few reports on the clinical...BACKGROUND Alström syndrome(AS,OMIM ID 203800)is a rare disease involving multiple organs in children and is mostly reported in non-Chinese patients.In the Chinese population,there are few reports on the clinical manifestations and pathogenesis of AS.This is the first report on the association between AS and Graves’hyperthyroidism.CASE SUMMARY An 8-year-old Chinese girl was diagnosed with AS.Two years later,Graves’hyperthyroidism developed with progressive liver dysfunction.The patient’s clinical data were collected;DNA from peripheral blood of the proband,parents and sibling was collected for gene mutation detection using the second-generation sequencing method and gene panel for diabetes.The association between the patient’s genotype and clinical phenotype was analyzed.She carried the pathogenic compound heterozygous mutation of ALMS1(c.2296_2299del4 and c.11460C>A).These stop-gain mutations likely caused truncation of the ALMS1 protein.CONCLUSION The manifestation of hyperthyroidism may suggest rapid progression of AS.展开更多
文摘目的:比较分析PLo S ALMs与Altmetrics评分、单篇论文学术评价指标之间的相关性及对单篇论文的评价效度。方法:以PLo S系列期刊PLo S Biology、PLo S Medicine为例,基于PLo S ALMs论文层面计量指标数据,分析比较其阅览量、下载量、讨论量、保存量、被引频次、推荐量与Altmetrics评分、h指数、学术迹T之间的相关性以及对单篇论文的评价效果。结果:阅览量、下载量、讨论量与被引频次、h指数有正相关性,推荐量与h指数、学术迹无关。Altmetrics评分与阅览量、下载量和讨论量呈中度相关性,与被引频次呈弱相关。结论:PLo S ALMs是一个多维评价,应该应用多指标测度,才能体现研究成果的综合实力。
文摘BACKGROUND Alström syndrome(AS,OMIM ID 203800)is a rare disease involving multiple organs in children and is mostly reported in non-Chinese patients.In the Chinese population,there are few reports on the clinical manifestations and pathogenesis of AS.This is the first report on the association between AS and Graves’hyperthyroidism.CASE SUMMARY An 8-year-old Chinese girl was diagnosed with AS.Two years later,Graves’hyperthyroidism developed with progressive liver dysfunction.The patient’s clinical data were collected;DNA from peripheral blood of the proband,parents and sibling was collected for gene mutation detection using the second-generation sequencing method and gene panel for diabetes.The association between the patient’s genotype and clinical phenotype was analyzed.She carried the pathogenic compound heterozygous mutation of ALMS1(c.2296_2299del4 and c.11460C>A).These stop-gain mutations likely caused truncation of the ALMS1 protein.CONCLUSION The manifestation of hyperthyroidism may suggest rapid progression of AS.
