BACKGROUND:The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated,and the incidence of postoperative complications has remained high.A set of novel magnetic compressive anastomats was int...BACKGROUND:The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated,and the incidence of postoperative complications has remained high.A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.METHODS:After ligating the common bile duct for 7 days,16 dogs were randomly divided into two groups (n=8 per group).Anastomats were used in the study group,and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy.We compared the operation time,incidence of complications,gross appearance,and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.RESULTS:The time spent on constructing the anastomosis for the study group was significantly shortened.Although no anastomotic stenosis occurred in the two groups,the narrowing rate of biliary-enteric anastomosis was much higher in the control group.There was one case of bile leakage in the control group,whereas no bile leakage occurred in the study group.A smoother surface,an improved layer apposition,and a lower local inflammatory response were identified in the anastomosis of the study group.CONCLUSION:The structures of the novel magnetic compressive anastomats are simple,and they are time-saving,safe and efficient for performing Roux-en-Y choledocho- jejunostomy procedures in a canine model of obstructive jaundice.展开更多
目的探讨内镜下聚桂醇硬化剂局部注射治疗Ⅱ~Ⅲ期内痔患者的临床效果。方法选取2019年3月—2021年3月普宁华侨医院120例内痔患者,依据随机数表法分为对照组和观察组,每组60例,对照组实施吻合器痔上黏膜环切术(procedure for prolapse an...目的探讨内镜下聚桂醇硬化剂局部注射治疗Ⅱ~Ⅲ期内痔患者的临床效果。方法选取2019年3月—2021年3月普宁华侨医院120例内痔患者,依据随机数表法分为对照组和观察组,每组60例,对照组实施吻合器痔上黏膜环切术(procedure for prolapse and hemorrhoid,PPH)治疗,观察组实施内镜下聚桂醇硬化剂局部注射治疗,比较两组患者临床疗效、手术一般情况、肛周疼痛程度、并发症以及复发率。结果观察组总有效率95.00%高于对照组,差异有统计学意义(χ^(2)=4.227,P<0.05);术前,两组患者视觉模拟评分法(visual analogue scale,VAS)对比,差异无统计学意义(P>0.05),观察组术后1、3、5 d VAS评分均低于对照组,差异有统计学意义(P<0.05)。结论内镜下聚桂醇硬化剂局部注射用于Ⅱ~Ⅲ期内痔患者的治疗,可改善术后一般情况,减轻疼痛,提高疗效,不增加并发症发生率以及复发率。展开更多
基金supported by a grant from the National Natural Science Foundation of China (30830099)
文摘BACKGROUND:The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated,and the incidence of postoperative complications has remained high.A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.METHODS:After ligating the common bile duct for 7 days,16 dogs were randomly divided into two groups (n=8 per group).Anastomats were used in the study group,and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy.We compared the operation time,incidence of complications,gross appearance,and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.RESULTS:The time spent on constructing the anastomosis for the study group was significantly shortened.Although no anastomotic stenosis occurred in the two groups,the narrowing rate of biliary-enteric anastomosis was much higher in the control group.There was one case of bile leakage in the control group,whereas no bile leakage occurred in the study group.A smoother surface,an improved layer apposition,and a lower local inflammatory response were identified in the anastomosis of the study group.CONCLUSION:The structures of the novel magnetic compressive anastomats are simple,and they are time-saving,safe and efficient for performing Roux-en-Y choledocho- jejunostomy procedures in a canine model of obstructive jaundice.
文摘目的探讨内镜下聚桂醇硬化剂局部注射治疗Ⅱ~Ⅲ期内痔患者的临床效果。方法选取2019年3月—2021年3月普宁华侨医院120例内痔患者,依据随机数表法分为对照组和观察组,每组60例,对照组实施吻合器痔上黏膜环切术(procedure for prolapse and hemorrhoid,PPH)治疗,观察组实施内镜下聚桂醇硬化剂局部注射治疗,比较两组患者临床疗效、手术一般情况、肛周疼痛程度、并发症以及复发率。结果观察组总有效率95.00%高于对照组,差异有统计学意义(χ^(2)=4.227,P<0.05);术前,两组患者视觉模拟评分法(visual analogue scale,VAS)对比,差异无统计学意义(P>0.05),观察组术后1、3、5 d VAS评分均低于对照组,差异有统计学意义(P<0.05)。结论内镜下聚桂醇硬化剂局部注射用于Ⅱ~Ⅲ期内痔患者的治疗,可改善术后一般情况,减轻疼痛,提高疗效,不增加并发症发生率以及复发率。
