In resonant grounding systems,most single-phaseto-ground faults evolve from IAFs(Intermittent Arc Faults).Earlier detection of IAFs can facilitate fault avoidance.This work proposes a novel method based on machine lea...In resonant grounding systems,most single-phaseto-ground faults evolve from IAFs(Intermittent Arc Faults).Earlier detection of IAFs can facilitate fault avoidance.This work proposes a novel method based on machine learning for detecting IAFs in three steps.First,the feature of zero-sequence current is automatically extracted and selected by a newlydesigned FINET(“For IAFs,Neuron Elaboration Net”),instead of traditional feature selection based on time-frequency decomposition.Moreover,data of the zero-sequence current divided by different time windows are successively input into the trained FINET.A proposed PSF(principal-subordinate factor)analyses the results obtained from FINET to improve anti-interference in the mentioned IAF detection algorithm.Experiments using PSCAD/EMTDC software simulation data show the proposed method is feasible and highly adaptable.In addition,the detection result of on-site recorded data demonstrates the effectiveness of the proposed method in practical resonant grounding systems.展开更多
The apoptosis repressor with caspase recruitment domain(ARC)plays a critical role in extrinsic apoptosis initiation via death receptor ligands,physiological stress,infection response in a tissue-dependent manner,endop...The apoptosis repressor with caspase recruitment domain(ARC)plays a critical role in extrinsic apoptosis initiation via death receptor ligands,physiological stress,infection response in a tissue-dependent manner,endoplasmic reticulum(ER)stress,genotoxic drugs,ionizing radiation,oxidative stress,and hypoxia.Recent studies have suggested that regulating apoptosis-related pathways can improve outcomes for patients with neurological diseases,such as hemorrhagic stroke.ARC expression is significantly correlated with acute cerebral hemorrhage.However,the mechanism by which it mediates the anti-apoptosis pathway remains poorly known.Here,we discuss the function of ARC in hemorrhagic stroke and argue that it could serve as an effective target for the treatment of hemorrhagic stroke.展开更多
基金sponsored by the National Natural Science Foundation of China (No.51677030).
文摘In resonant grounding systems,most single-phaseto-ground faults evolve from IAFs(Intermittent Arc Faults).Earlier detection of IAFs can facilitate fault avoidance.This work proposes a novel method based on machine learning for detecting IAFs in three steps.First,the feature of zero-sequence current is automatically extracted and selected by a newlydesigned FINET(“For IAFs,Neuron Elaboration Net”),instead of traditional feature selection based on time-frequency decomposition.Moreover,data of the zero-sequence current divided by different time windows are successively input into the trained FINET.A proposed PSF(principal-subordinate factor)analyses the results obtained from FINET to improve anti-interference in the mentioned IAF detection algorithm.Experiments using PSCAD/EMTDC software simulation data show the proposed method is feasible and highly adaptable.In addition,the detection result of on-site recorded data demonstrates the effectiveness of the proposed method in practical resonant grounding systems.
基金National Natural Science Foundation of China(No.30470642and No.30670780)Shandong Province Tackle Key Problems in Science and Technology Program(2008GG10002006)+1 种基金Qingdao Municipal Scienceand Technology Commission(05-1-JC-93)Shandong province Health Department 266021(2007-37)~~
基金supported by the Shanghai Hospital Development Center(grant number:SHDC2020CR3021A,to YG)the National Natural Science Foundation of China(grant number:82072788,to YG).
文摘The apoptosis repressor with caspase recruitment domain(ARC)plays a critical role in extrinsic apoptosis initiation via death receptor ligands,physiological stress,infection response in a tissue-dependent manner,endoplasmic reticulum(ER)stress,genotoxic drugs,ionizing radiation,oxidative stress,and hypoxia.Recent studies have suggested that regulating apoptosis-related pathways can improve outcomes for patients with neurological diseases,such as hemorrhagic stroke.ARC expression is significantly correlated with acute cerebral hemorrhage.However,the mechanism by which it mediates the anti-apoptosis pathway remains poorly known.Here,we discuss the function of ARC in hemorrhagic stroke and argue that it could serve as an effective target for the treatment of hemorrhagic stroke.