Diffusion-weighted magnetic resonance imaging(DWI) provides image contrast that is different from that obtained by conventional magnetic resonance techniques.Although previously,DWI has been used to evaluate various d...Diffusion-weighted magnetic resonance imaging(DWI) provides image contrast that is different from that obtained by conventional magnetic resonance techniques.Although previously,DWI has been used to evaluate various diseases of the central nervous system,several technical advances have expanded the clinical applications of DWI beyond the central nervous system.As a result,many reports have been published on the use of DWI in abdominal diseases.Particularly,abdominal DWI has now being focused on evaluation of patients with abdominal cancer.DWI can be used for pretreatment tumor detection,characterization including predicting tumor response to therapy,monitoring tumor response during therapy,and follow-up study after treatment to detect possible tumor recurrence.展开更多
Objective：Blood biochemistry,ascites tests,and imaging examinations have low sensitivities in abdominal neoplasm diagnoses.In addition,exploratory laparotomy is not suitable for final stage patients.Mini-laparoscopy ...Objective：Blood biochemistry,ascites tests,and imaging examinations have low sensitivities in abdominal neoplasm diagnoses.In addition,exploratory laparotomy is not suitable for final stage patients.Mini-laparoscopy has recently emerged as a new diagnostic technology for abdominal disease.The aim of this research was to evaluate the value of mini-laparoscopy in diagnosing abdominal neoplasms.Methods：Clinical and operational data were retrospectively analyzed in 20 cases with pathologically confirmed abdominal malignancies.Of these,10 cases were each diagnosed by mini-laparoscopy and exploratory laparotomy.The surgical and anesthesia expenses,perioperative nursing,monitoring and treating charges,postoperative hospital stay and complications were compared between groups.Results：The surgical and anesthesia costs were statistically lower in patients who received a mini-laparoscopy （P0.01）.Perioperative drug expenses and nursing and monitoring charges were also significantly decreased （P0.05 and P0.01,respectively）.Further,the gastrointestinal function recovery time and postoperative hospital stay were significantly reduced in the mini-laparoscopy group.There was no significant difference between the two groups regarding the preoperative hospital stay and postoperative complications.Conclusion：Mini-laparoscopy effectively reduces surgical injury and treatment costs,and is capable of safely diagnosing abdominal tumors.Moreover,the procedure is also easy to perform.展开更多
BACKGROUND Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life.They usually occur in the mediastinum or lung,but there are very rare cases of ectopic broncho...BACKGROUND Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life.They usually occur in the mediastinum or lung,but there are very rare cases of ectopic bronchogenic cysts that develop in the abdominal cavity.A unique intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm that was producing carcinoembryonic antigen(CEA),harboring a GNAS mutation,is reported.The present case may contribute to clarifying the mechanism of tumorigenesis and malignant transformation of ectopic bronchogenic cysts.CASE SUMMARY In 2007,a man in his 50s was incidentally found to have an intra-abdominal cystic mass,8 cm in diameter.Surgical resection was recommended,but he preferred to remain under observation.In 2020,his serum CEA level increased to 26.7 ng/mL,and abdominal computed tomography showed a 15 cm×12 cm,multifocal,cystic mass located predominantly on the lesser curvature of the stomach.Since malignancy could not be ruled out,he finally underwent surgical resection.Histologically,the cystic wall was lined by ciliated columnar epithelium,accompanied by bronchial gland-like tissue,bronchial cartilage,and smooth muscle.Part of the cyst consisted of atypical columnar epithelium with an MIB-1 index of 5%and positive for CEA.Moreover,a GNAS mutation(p.R201C)was detected in the atypical epithelium,leading to a diagnosis of an ectopic bronchogenic cyst with a low-grade mucinous neoplasm.The patient is currently undergoing outpatient follow-up without recurrence.CONCLUSION An extremely rare case of an abdominal bronchogenic cyst with a low-grade mucinous neoplasm harboring a GNAS mutation was reported.展开更多
文摘Diffusion-weighted magnetic resonance imaging(DWI) provides image contrast that is different from that obtained by conventional magnetic resonance techniques.Although previously,DWI has been used to evaluate various diseases of the central nervous system,several technical advances have expanded the clinical applications of DWI beyond the central nervous system.As a result,many reports have been published on the use of DWI in abdominal diseases.Particularly,abdominal DWI has now being focused on evaluation of patients with abdominal cancer.DWI can be used for pretreatment tumor detection,characterization including predicting tumor response to therapy,monitoring tumor response during therapy,and follow-up study after treatment to detect possible tumor recurrence.
文摘Objective：Blood biochemistry,ascites tests,and imaging examinations have low sensitivities in abdominal neoplasm diagnoses.In addition,exploratory laparotomy is not suitable for final stage patients.Mini-laparoscopy has recently emerged as a new diagnostic technology for abdominal disease.The aim of this research was to evaluate the value of mini-laparoscopy in diagnosing abdominal neoplasms.Methods：Clinical and operational data were retrospectively analyzed in 20 cases with pathologically confirmed abdominal malignancies.Of these,10 cases were each diagnosed by mini-laparoscopy and exploratory laparotomy.The surgical and anesthesia expenses,perioperative nursing,monitoring and treating charges,postoperative hospital stay and complications were compared between groups.Results：The surgical and anesthesia costs were statistically lower in patients who received a mini-laparoscopy （P0.01）.Perioperative drug expenses and nursing and monitoring charges were also significantly decreased （P0.05 and P0.01,respectively）.Further,the gastrointestinal function recovery time and postoperative hospital stay were significantly reduced in the mini-laparoscopy group.There was no significant difference between the two groups regarding the preoperative hospital stay and postoperative complications.Conclusion：Mini-laparoscopy effectively reduces surgical injury and treatment costs,and is capable of safely diagnosing abdominal tumors.Moreover,the procedure is also easy to perform.
文摘BACKGROUND Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life.They usually occur in the mediastinum or lung,but there are very rare cases of ectopic bronchogenic cysts that develop in the abdominal cavity.A unique intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm that was producing carcinoembryonic antigen(CEA),harboring a GNAS mutation,is reported.The present case may contribute to clarifying the mechanism of tumorigenesis and malignant transformation of ectopic bronchogenic cysts.CASE SUMMARY In 2007,a man in his 50s was incidentally found to have an intra-abdominal cystic mass,8 cm in diameter.Surgical resection was recommended,but he preferred to remain under observation.In 2020,his serum CEA level increased to 26.7 ng/mL,and abdominal computed tomography showed a 15 cm×12 cm,multifocal,cystic mass located predominantly on the lesser curvature of the stomach.Since malignancy could not be ruled out,he finally underwent surgical resection.Histologically,the cystic wall was lined by ciliated columnar epithelium,accompanied by bronchial gland-like tissue,bronchial cartilage,and smooth muscle.Part of the cyst consisted of atypical columnar epithelium with an MIB-1 index of 5%and positive for CEA.Moreover,a GNAS mutation(p.R201C)was detected in the atypical epithelium,leading to a diagnosis of an ectopic bronchogenic cyst with a low-grade mucinous neoplasm.The patient is currently undergoing outpatient follow-up without recurrence.CONCLUSION An extremely rare case of an abdominal bronchogenic cyst with a low-grade mucinous neoplasm harboring a GNAS mutation was reported.
