An acousto-optic Q-switched fiber laser using China-made double-cladding fiber

A simple laser-diode pumped acoustic-optic Q-switched fiber laser is reported by using China-made largemode-area ytterbium-doped fiber. Q-switched pulses with a beam quality factor of M^2 ≈ 2 and several hundred nanoseconds pulse duration are achieved at the repetition rate of 1 - 50 kHz. When the repetition rate is 1 kHz, the pulse energy is 0.93 mJ with the pulse duration of 132 ns. Meanwhile, the profile of laser pulses shows some mode-locking phenomena, the mechanism of the phenomena is discussed.

Continuous wave and active Q-switched operation of Watt-level LED-pumped two-rod Nd,Ce:YAG laser

A high-performance LED-side-pumped two-rod Nd,Ce:YAG laser with continuous-wave(CW) and acousto–optical(A-O) Q-switched operation is demonstrated in this work. A symmetrically shaped flat–flat cavity with two identical LEDside-pumped laser modules is employed for power scalability. In the CW regime, the maximum output average power of laser at 1064 nm is 4.41 W, corresponding to a maximum optical conversion efficiency of 5.3% and a slope efficiency is 12.4%. In the active Q-switched regime, the pulse energy of laser reaches as high as 0.89 m J at a repetition rate of 800 Hz with a pulse width of 457.2 ns, the corresponding highest peak output power is 1.94 k W and the M~2 factor is measured to be about 8.8. To the best of the authors' knowledge, this is the first demonstration and the highest performance of a CW LED-side-pumped two-rod laser Nd,Ce:YAG with Watt-level output reported so far.

High-power xenon lamp-pumped Er:YAP pulse laser operated in free-running and acousto-optical Q-switching modes

We demonstrate a high-energy and high-power pulse laser on a xenon lamp-pumped Er:YAP crystal. The laser performance and thermal focal lengths under different working frequencies are discussed. The results show that the thermal lens effect is gradually aggravated with the increase of working frequencies, and even working at 100 Hz, a single pulse energy of 234 m J can be achieved. A maximum average power of 41.5 W is achieved with a working frequency of 20 Hz and slope efficiency of 2.82%. This output power is much higher than other xenon lamp-pumped erbium laser devices.A Q-switched laser is demonstrated by using the TeO2crystal, the maximum output energies of 11.5 m J and 3.5 m J are obtained at 50 and 100 Hz, the corresponding peak powers are 93.4 k W and 17.2 kW, respectively.The laser wavelengths and beam quality factors are also characterized in the free-running and Q-switched modes. A higher pulse energy and peak power laser could be achieved further by improving the damage threshold of TeO2acousto-optical Q-switching. All the experimental results illustrate that the xenon lamp-pumped Er:YAP laser is a promising candidate for high-power and high-frequency mid-infrared laser devices.

Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's disease.Consequently,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and progression.Nonetheless,nonpharmacological interventions aimed at inducing adult neurogenesis are currently limited.Although individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully explored.In this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 months.Amyloid deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease progressed.However,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus decreased.These findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 mice.Furthermore,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice following multifactor stimulation,as evidenced by Morris water maze,novel object recognition,forced swimming test,and tail suspension test results.Notably,the efficacy of multifactor stimulation in consolidating immature neurons persisted for at least 2weeks after treatment cessation.At the molecular level,multifactor stimulation upregulated the expression of neuron-related proteins(NeuN,doublecortin,postsynaptic density protein-95,and synaptophysin),anti-apoptosis-related proteins(Bcl-2 and PARP),and an autophagyassociated protein(LC3B),while decreasing the expression of apoptosis-related proteins(BAX and caspase-9),in the hippocampus of amyloid precursor protein/presenilin 1 mice.These observations might be attributable to both the brain-derived neurotrophic factor-mediated signaling pathway and antioxidant pathways.Furthermore,serum metabolomics analysis indicated that multifactor stimulation regulated differentially expressed metabolites associated with cell apoptosis,oxidative damage,and cognition.Collectively,these findings suggest that multifactor stimulation is a novel non-invasive approach for the prevention and treatment of Alzheimer's disease.

Acousto-Optically Q-Switched Operation of Yb:CNGG Disordered Crystal Laser

We report the repetitively Q-switched laser operation of the Yb-doped calcium niobium gallium garnet disordered garnet crystal, achieved with an acousto-optic modulator in a compact plano-concave resonator that is endpumped by a 935-nm diode laser. An average output power of 1.96 W is produced at pulse repetition rate of50 k Hz at emission wavelengths around 1035 nm, with a slope efficiency of 16%. The highest pulse energy of 269 μJ is generated at pulse repetition rate of 1 k Hz, with pulse width 12.1 ns and peak power 20.53 kW.

High-Power Continuous-Wave and Acousto-Optical Q-Switched Ho:(Sc_(0.5)Y_(0.5))_2SiO_5 Laser Pumped by Laser Diode

We experimentally investigate the continuous-wave(cw)and acousto-optical(AO)Q-switched performance of a diode-pumped Ho:(Sc_(0.5)Y_(0.5))_2SiO_5(Ho:SYSO)laser.A fiber-coupled laser diode at 1.91m is employed as the pump source.The cw Ho:SYSO laser produces 13.0 W output power at 2097.9 nm and 56.0%slope efficiency with respect to the absorbed pump power.In the AO Q-switched regime,at a pulse repetition frequency of 5 kHz,the Ho:SYSO laser yields 2.1 mJ pulse energy and 21 ns pulse width,resulting in a calculated peak power of 100 k W.In addition,at the maximum output level,the beam quality factor of the Q-switched Ho:SYSO laser is measured to be about 1.6.

Acousto-optic scanning spatial-switching multiphoton lithography

Nano-3D printing has obtained widespread attention owing to its capacity to manufacture end-use components with nano-scale features in recent years.Multiphoton lithography(MPL)is one of the most promising 3D nanomanufacturing technologies,which has been widely used in manufacturing micro-optics,photonic crystals,microfluidics,meta-surface,and mechanical metamaterials.Despite of tremendous potential of MPL in laboratorial and industrial applications,simultaneous achievement of high throughput,high accuracy,high design freedom,and a broad range of material structuring capabilities remains a long-pending challenge.To address the issue,we propose an acousto-optic scanning with spatial-switching multispots(AOSS)method.Inertia-free acousto-optic scanning and nonlinear swept techniques have been developed for achieving ultrahigh-speed and aberration-free scanning.Moreover,a spatial optical switch concept has been implemented to significantly boost the lithography throughput while maintaining high resolution and high design freedom.An eight-foci AOSS system has demonstrated a record-high 3D printing rate of 7.6×10^(7)voxel s^(-1),which is nearly one order of magnitude higher than earlier scanning MPL,exhibiting its promise for future scalable 3D nanomanufacturing.

Watt-level acousto-optically Q-switched Pr:YLF laser at 639 nm

We present a study on a watt-level acousto-optically Q-switched Pr:YLF laser at three different repetition rates(10 kHz,20 kHz,and 50 kHz)for the first time,to the best of our knowledge.The corresponding average output powers and pulse widths were measured to be 1.14 W,1.2 W,and 1.32 W,and 40 ns,52 ns,and 80 ns,respectively.A maximum pulse energy of0.11 mJ was obtained,corresponding to a peak power of up to 2.8 kW at a repetition rate of 10 kHz.The simulated dynamics of a fast Q-switched Pr:YLF laser is in agreement with the experiment.The laser's ability to generate stable pulses with high peak power and short pulse width makes it highly desirable for various practical applications,such as laser machining and material processing.

Antimonene-based saturable absorber for a soliton mode-locked and Q-switched fiber laser in the 2 μm wavelength region

We demonstrate antimonene as a saturable absorber(SA) to generate an ultrafast mode-locked and Q-switched laser in the 2 μm wavelength region. The two antimonene-based SAs were prepared and inserted separately in a thulium–holmiumdoped fiber laser to produce the pulsed laser. Antimonene was coated onto a tapered fiber to generate soliton mode-locked pulses and used in thin-film form for the generation of Q-switched pulses. The mode-locking was stable within a pump power of 267 m W–511 m W, and the laser operated at a central wavelength of 1897.4 nm. The mode-locked laser had a pulse width of 1.3 ps and a repetition rate of 12.6 MHz, with a signal-to-noise ratio of 64 d B. Q-switched laser operation was stable at a wavelength of 1890.1 nm within a pump power of 312 m W–381 m W. With the increase in pump power from 312 m W to 381 m W, the repetition rate increased to a maximum of 56.63 k Hz and the pulse width decreased to a minimum value of 2.85 μs. Wide-range tunability of the Q-switched laser was also realized within the wavelength range of1882 nm–1936 nm.

Development of miniaturized SAF-LIBS with high repetition rate acousto-optic gating for quantitative analysis

The self-absorption effect in laser-induced breakdown spectroscopy(LIBS)reduces the accuracy of quantitative measurement results.The self-absorption-free LIBS(SAF-LIBS)has been proved to directly capture the optically thin plasma spectra by setting an appropriate exposure time.In this work,a novel SAF-LIBS technique with high repetition rate acousto-optic gating is developed,in which an acousto-optic modulator is used as the shutter to diffract the optically thin fluorescence,and a high repetition rate laser is used to produce quasi-continuous plasmas to enhance the integral spectral intensity,so that the CCD spectrometer can replace an intensified CCD(ICCD)and echelle spectrometer in SAF-LIBS.Experimental results show that the average absolute prediction error of aluminum is reduced to 0.18%,which is equivalent to that of traditional SAF-LIBS.This technique not only effectively shields continuous background radiation and broadened spectral lines in optically thick plasma,but also has advantages of miniaturization,low cost,convenience and reliability.

High stability and low noise laser-diode end-pumped Nd:YAG ceramic passively Q-switched laser at 1123 nm based on a Ti_(3)C_(2)T_(x)-PVA saturable absorber

We report a high repetition frequency, high power stability and low laser noise laser-diode(LD) end-pumped Nd: YAG ceramic passively Q-switched laser at 1123 nm based on a Ti_(3)C_(2)T_(x)-polyvinyl alcohol(PVA) film as a saturable absorber(SA). A Brewster polarizer(BP) and a birefringent crystal(BC) are incorporated to enable frequency selection and filtering for the passively Q-switched 1123 nm pulsed laser to improve the power stability and reduce the noise. When the pump power is 5.1 W, an average output power of 457.9 m W is obtained, corresponding to a repetition frequency of 1.09 MHz,a pulse width of 56 ns, a spectral line width of 0.65 nm, a power instability of ±0.92%, and a laser noise of 0.89%.The successful implementation of the “Ti_(3)C_(2)T_(x)-PVA film passively Q-switching” combined with “frequency selection and filtering of BP + BC” technology path provides a valuable reference for developing pulsed laser with high repetition frequency, high stability and low noise.

A Laser-Diode-Pumped Nd:YAG Laser Q-Switched with a YAG Color Center Chip

A laser-diode-pumped Nd: YAG laser Q-switched Passively with a YAG colorcenter chip has been deveolped. The Q-switched pulse output has a duration of 25-70ns,an energy of about 7.9 μJ and a repetition frequency of 1.25-5.0kHz when the laser cavityparameters and pump power are changed. The Q-switched dynamics is analyzed with therate equation theorry. The theoretical and experimental results agree well.

Controlling and synchronizing spatiotemporal chaos of the coupled Bragg acousto-optical bistable map system using nonlinear feedback

In this paper we present the control and synchronization of a coupled Bragg acousto-optic bistable map system using nonlinear feedback technology. This nonlinear feedback technology is useful to control a temporally chaotic system as well as a spatiotemporally chaotic system. It can be extended to synchronize the spatiotemporal chaos. It can work in a wide range of the controlled and synchronized signals, so it can decrease the sensitivity down to a noise level. The synchronization can be obtained by the analysis of the largest conditional Lyapunov exponent spectrum, and easily implemented in practical systems just by adjusting the coupled strength without any pre-knowledge of the dynamic system required.

1.5-MHz repetition rate passively Q-switched Nd:YVO4 laser based on WS2 saturable absorber

A transmission-type tungsten disulfide（WS_2）-based saturable absorber（SA） is fabricated and applied to passively Q-switched Nd：YVO_4 laser.The WS_2 nanosheets are deposited on a quartz substrate by the vertical evaporation method.By inserting the WS2 SA into the plano-concave laser cavity,we achieve 153-ns pulses with an average output power of1.19 W at 1064 nm.To the best of our knowledge,both of them are the best results among those obtained by the Q-switched solid-state lasers with WS_2-based absorbers.The repetition rate ranges from 1.176 MHz to 1.578 MHz.As far as we know,it is the first time that MHz level Q-switched pulses have been generated in all solid state lasers based on low-dimensional materials so far.

A compact graphene Q-switched erbium-doped fiber laser using optical circulator and tunable fiber Bragg grating

We demonstrate a passively Q-switched tunable erbium-doped fiber laser （EDFL） based on graphene as a saturable absorber （SA）. A three-port optical circulator （OC） and a strain-induced tunable fiber Bragg grating （TFBG） are used as the two end mirrors in an all-fiber linear cavity. The Q-switched EDFL has a low pump threshold of 23.8 mW. The pulse repetition rate of the fiber laser can be widely changed from 9.3 kHz to 69.7 kHz by increasing the pump power from 23.8 mW to 219.9 mW. The minimum pulse duration is 1.7 p.s and the highest pulse energy is 25.4 nJ. The emission wavelength of the laser can be tuned from 1560.43 nm to 1566.27 nm by changing the central wavelength of the straininduced TFBG.

Passively Q-switched diode-pumped Tm,Ho:LuVO4 laser with a black phosphorus saturable absorber

We presented a passively Q-switched(PQS) diode-pumped c-cut Tm, Ho:LuVO_4 laser with a black phosphorus saturable absorber for the first time.Under PQS mode, an average output power of 0.86 W and a peak power of 2.32 W were acquired from the Tm, Ho:LuVO4 laser with the pump power of 14.55 W, corresponding to a pulse width of 2.89 μs,a pulse repetition rate of 71.84 kHz, and a pulse energy of about 6.70 μJ.

Passively Q-switched dual-wavelength Yb：LSO laser based on tungsten disulphide saturable absorber

We demonstrate a passively Q-switched Yb：LSO laser based on tungsten disulphide （WS2） saturable absorber op- erating at 1034 nm and 1056 nm simultaneously. The saturable absorbers were fabricated by spin coating method. With low speed, the WS2 nanoplatelets embedded in polyvinyl alcohol could be coated on a BK7 glass substrate coated with high-refractive-index thin polymer. The shortest pulse width of 1.6 gs with a repetition rate of 76.9 kHz is obtained. As the pump power increases to 9 W, the maximum output power is measured to be 250 mW, corresponding to a single pulse energy of 3.25 μJ. To the best of our knowledge, this is the first time to obtain dual-wavelength Q-switched solid-state laser using few-layer WS2 nanoplatelets.

A Modified Monte Carlo Model of Speckle Tracking of Shear Wave Induced by Acoustic Radiation Force for Acousto-Optic Elasticity Imaging

A modified Monte Carlo model of speckle tracking of shear wave propagation in scattering media is proposed. The established Monte Carlo model mainly concerns the variations of optical electric field and speckle. The two- dimensional intensity distribution and the time evolution of speckles in different probe locations are obtained. The fluctuation of speckle intensity tracks the acoustic-radiation-force shear wave propagation, and especially the reduction of speckle intensity implies attenuation of shear wave. Then, the shear wave velocity is estimated quantitatively on the basis of the time-to-peak algorithm and linear regression processing. The results reveal that a smaller sampling interval yields higher estimation precision and the shear wave velocity is estimated more efficiently by using speckle intensity difference than by using speckle contrast difference according to the estimation error. Hence, the shear wave velocity is estimated to be 2.25 m/s with relatively high accuracy for the estimation error reaches the minimum （0.071）.

Q-Switched Raman Fiber Laser with Molybdenum Disulfide-Based Passive Saturable Absorber

We demonstrate a Q-switched Raman fiber laser using molybdenum disulfide （MoS2） as a saturable absorber （SA）. The SA is assembled by depositing a mechanically exfoliated MoS2 onto a fiber ferrule facet before it is matched with another clean ferrule via a connector. It is inserted in a Raman fiber laser cavity with a total cavity length of about 8kin to generate a Q-switching pulse train operating at 1560.2nm. A 7.7-kin-long dispersion compensating fiber with 584 ps.nm-i km-1 of dispersion is used as a nonlinear gain medium. As the pump power is increased from 395 m W to 422 m W, the repetition rate of the Q-switching pulses can be increased from 132.7 to 137.4 kHz while the pulse width is concurrently decreased from 3.35μs to 3.03μs. The maximum pulse energy of 54.3 nJ is obtained at the maximum pump power of 422 roW. These results show that the mechanically exfoliated MoS2 SA has a great potential to be used for pulse generation in Raman fiber laser systems.

Passively Q-Switched Nd,Cr:YAG Laser Simultaneous Dual-Wavelength Operation at 946 nm and 1.3μm

A diode-end-pumped Q-switched high-efficiency Nd, Cr：YAG laser with simultaneous dual-wavelength emission at 946nm and 1.3μm is demonstrated. The maximum output power of 1.93 W with simultaneous dual-wavelength operation is achieved at an absorbed pump power of 13.32 W and an absorbed slope efficiency of 15.15%. The maximum optical-optical efficiency is 14.49% with pulse widths of 16.38ns at 946nm and 26.65ns at 1.3μm. A maximum total repetition rate of 43.25 kHz is obtained.