BACKGROUND Biliary adenofibromas(BAFs)are rare primary hepatic neoplasms,some of which can potentially undergo malignant transformation.Here,we describe a rare case of malignant transformation of BAF.CASE SUMMARY A 51...BACKGROUND Biliary adenofibromas(BAFs)are rare primary hepatic neoplasms,some of which can potentially undergo malignant transformation.Here,we describe a rare case of malignant transformation of BAF.CASE SUMMARY A 51-year-old female was referred to our hospital with epigastric pain.Computed tomography showed a solitary liver mass combined with the enlargement of multiple mediastinal and cervical lymph nodes,clinically mimicking a liver carcinoma with extensive lymph node metastasis.However,core needle biopsy suggested BAF with malignant transformation.Finally,the patient underwent curative resection of the neoplasm and was recurrence-free for 12 mo.CONCLUSION Our case serves as an example of a rare manifestation of BAF.Our report and the previously published experience,reinforce that curative resection should be considered the primary treatment for BAFs with malignant transformation,leading to a favorable prognosis.展开更多
BACKGROUND Biliary adenofibroma(BF)is a rare benign epithelial tumor with the possibility of malignant transformation.Its main pathological feature is a well-defined cystic or honeycomb mass.BF has no specific clinica...BACKGROUND Biliary adenofibroma(BF)is a rare benign epithelial tumor with the possibility of malignant transformation.Its main pathological feature is a well-defined cystic or honeycomb mass.BF has no specific clinical manifestations or laboratory and imaging findings;thus,it is easily misdiagnosed before surgery.This report describes a case in which biliary cystadenoma was misdiagnosed preoperatively and BF was diagnosed postoperatively.The imaging features,particularly the magnetic resonance imaging(MRI)features,were analyzed and summarized.CASE SUMMARY A 68-year-old Chinese man was admitted to our hospital with a 2-mo history of abdominal discomfort.Following admission to our hospital,laboratory examinations showed normal tumor marker concentrations and liver function.Hepatocellular carcinoma was considered after contrast-enhanced ultrasound examination.MRI suggested the possibility of cystadenoma of the bile duct.However,postoperative pathological examination confirmed the diagnosis of BF.No local recurrence was found 1 mo after surgery.CONCLUSION Our objective is to highlight the imaging diagnostic value of BF,especially on an MRI enhanced scan with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid.展开更多
基金Supported by Innovative Project of Medical and Health Science,Zhejiang Province,No.2021RC002。
文摘BACKGROUND Biliary adenofibromas(BAFs)are rare primary hepatic neoplasms,some of which can potentially undergo malignant transformation.Here,we describe a rare case of malignant transformation of BAF.CASE SUMMARY A 51-year-old female was referred to our hospital with epigastric pain.Computed tomography showed a solitary liver mass combined with the enlargement of multiple mediastinal and cervical lymph nodes,clinically mimicking a liver carcinoma with extensive lymph node metastasis.However,core needle biopsy suggested BAF with malignant transformation.Finally,the patient underwent curative resection of the neoplasm and was recurrence-free for 12 mo.CONCLUSION Our case serves as an example of a rare manifestation of BAF.Our report and the previously published experience,reinforce that curative resection should be considered the primary treatment for BAFs with malignant transformation,leading to a favorable prognosis.
文摘BACKGROUND Biliary adenofibroma(BF)is a rare benign epithelial tumor with the possibility of malignant transformation.Its main pathological feature is a well-defined cystic or honeycomb mass.BF has no specific clinical manifestations or laboratory and imaging findings;thus,it is easily misdiagnosed before surgery.This report describes a case in which biliary cystadenoma was misdiagnosed preoperatively and BF was diagnosed postoperatively.The imaging features,particularly the magnetic resonance imaging(MRI)features,were analyzed and summarized.CASE SUMMARY A 68-year-old Chinese man was admitted to our hospital with a 2-mo history of abdominal discomfort.Following admission to our hospital,laboratory examinations showed normal tumor marker concentrations and liver function.Hepatocellular carcinoma was considered after contrast-enhanced ultrasound examination.MRI suggested the possibility of cystadenoma of the bile duct.However,postoperative pathological examination confirmed the diagnosis of BF.No local recurrence was found 1 mo after surgery.CONCLUSION Our objective is to highlight the imaging diagnostic value of BF,especially on an MRI enhanced scan with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid.
