BACKGROUND To investigate the clinicopathological features of endometrial clear cell carcinoma that has invaded the right oviduct with a cooccurring ipsilateral oviduct adenomatoid tumor.CASE SUMMARY A case of endomet...BACKGROUND To investigate the clinicopathological features of endometrial clear cell carcinoma that has invaded the right oviduct with a cooccurring ipsilateral oviduct adenomatoid tumor.CASE SUMMARY A case of endometrial clear cell carcinoma invading the right oviduct with a cooccurring ipsilateral oviduct adenomatoid tumor was collected and analyzed using pathomorphology and immunohistochemistry.Endometrial clear cell carcinoma cells were distributed in a solid nest,papillary,shoe nail-like,and glandular tube-like distribution.There was infiltrative growth,and tumor cells had clear cytoplasm and obvious nuclear heteromorphism.The cancer tissue was necrotic and mitotic.The cancer tissue invaded the right oviduct.The ipsilateral oviduct also had an adenomatoid tumor.The adenomatoid tumor was arranged in microcapsules lined with flat or cubic cells that were surrounded by smooth muscle tissue.The adenomatoid tumor cells were round in shape.CONCLUSION Clear cell carcinoma of the endometrium can invade the oviduct and occur simultaneously with tubal adenomatoid tumors.Upon pathological diagnosis,one should pay close attention to distinguishing whether an endometrial clear cell carcinoma is invading the oviduct or whether it is accompanied by an adenomatoid tumor of the oviduct.Immunohistochemistry is helpful to differentiate these two disease entities.Endometrial clear cell carcinomas express Napsin-A and P16 and are negative for estrogen receptor and progesterone receptor.The presence of endometrial clear cell carcinoma does not affect the expression of CK and calretinin in adenomatoid tumors.展开更多
Objective: To investigate the relation between eosinophilic materials and amyloid P (AP) component in adenomatoid odontogenic tumor (AOT). Methods: The expression of amyloid proteins and basement membrane proteins, in...Objective: To investigate the relation between eosinophilic materials and amyloid P (AP) component in adenomatoid odontogenic tumor (AOT). Methods: The expression of amyloid proteins and basement membrane proteins, including type IV collagen, laminin and heparin sulfate proteoglycan (HSPG), in AOT were analyzed by immunohistochemical method. Results: Most eosinophilic droplets among tumor cells and some epithelial cells showed positive stain for AP component. The immunoreactions of type IV collagen and laminin were only found in blood vessels of this tumor. The tumor cells and eosinophilic materials in duct-like structures were constantly unstained for both amyloid and basement membrane proteins. Present results suggest that the nature and composition of eosinophilic droplets may differ from the eosinophilic layer in ductlike structures. This study first demonstrated that the amyloid-like deposition in AOT is associated with AP component by immunohistochemical method. It supported that AP component may be epithelial origin since the AP immunolocalization was found in tumor cells.展开更多
Adenomatoid odontogenic tumor is an unusual benign neoplasm which shares clinical and radiographic characteristics with odontogenic cystic lesions denoting a distinct behavior. This paper reports a case of a 12-year-o...Adenomatoid odontogenic tumor is an unusual benign neoplasm which shares clinical and radiographic characteristics with odontogenic cystic lesions denoting a distinct behavior. This paper reports a case of a 12-year-old boy with a bony consistence tumefaction involving the area from teeth 12 to 17. Radiographically, the lesion was characterized by a well-circum- scribed unilocular radiolucent area displacing maxillary canine, first and second premolars. The final diagnosis was adenomatoid odontogenic tumour. The lesion was enucleated concomitantly with the removal of the canine tooth under general anesthesia. The patient was submitted to orthodontic treatment and has been followed-up for four years. Clinical and radiographic features are discussed in this report.展开更多
Benign multicystic peritoneal mesothelioma （BMPM） is a rare tumor that occurs mainly in women in their reproductive age. The pathogenesis of BMPM is unclear and a controversy regarding its neoplastic and reactive na...Benign multicystic peritoneal mesothelioma （BMPM） is a rare tumor that occurs mainly in women in their reproductive age. The pathogenesis of BMPM is unclear and a controversy regarding its neoplastic and reactive nature exists. The biological behavior of BMPM is characterized by its slowly progressive process and high rate of recurrence after surgical resection. In addition this lesion does not present a strong tendency to transform into malignancy. Today approximately 130 cases have been reported. We here report a 62-year-old woman who had diffuse abdominal pain, nausea and vomiting. Physical examination revealed a painful mass in her upper abdomen. She reported a mild dehydration, but the vital signs were normal. Peristaltic rushes, gurgles and highpitched tinkles were audible. Upright plain abdominal film revealed small bowel loops with air-fluid levels. She was diagnosed having an incarcerated incisional hernia that resulted in intestinal obstruction. The patient underwent surgery during which a cystic mass of the right ovary measuring 6 cm × 5 cm × 4 cm, four small cysts of the small bowel （1 cm in diameter） and a cyst at the retroperitoneum measuring 11 cm× 10 cm × 3 cm were found. Complete resection of the lesion was performed. The patient had an uneventful recovery and had no recurrence two years after surgery.展开更多
Adenomatoid tumors are the most commonly located .in male and female genital tracts, but they are rarely found in extragenital locations, especially in adrenal glands. These tumors are considered as benign neoplasms o...Adenomatoid tumors are the most commonly located .in male and female genital tracts, but they are rarely found in extragenital locations, especially in adrenal glands. These tumors are considered as benign neoplasms of mesothelial derivation, and pathologically show glandular tubules lined by epitheloid cells with intervening trabeculae with a characteristic mixture of adenoidal, angiomatoid, cystic and solid patterns, in addition to focal calcifications and signet-ring like cells frequently.2 Because of the lack of radiological specificity,展开更多
Adenomatoid tumors （ATs） are benign neoplasms that most commonly occur in the genital tracts of both male and females. Extragenital ATs are rare and have been reported in the pleura, heart, omentum, the mesentery of...Adenomatoid tumors （ATs） are benign neoplasms that most commonly occur in the genital tracts of both male and females. Extragenital ATs are rare and have been reported in the pleura, heart, omentum, the mesentery of the small intestine, pancreas, mediastinal lymph nodes and peri-umbilical skin. 1,2 AT of the adrenal gland is typically an asymptomatic neoplasm with benign behavior, which has been recently recognized as a diagnostic challenge, as it is both rare and can present in such a manner as to suggest a wide range of differential diagnoses. 1,3-8 Here we report a very large AT of the left adrenal gland, which at present appears to be the largest tumor of this type that has ever been reported. It may be the first case of AT associated with a high level of plasma adrenocorticotropic hormone （ACTH）.展开更多
文摘BACKGROUND To investigate the clinicopathological features of endometrial clear cell carcinoma that has invaded the right oviduct with a cooccurring ipsilateral oviduct adenomatoid tumor.CASE SUMMARY A case of endometrial clear cell carcinoma invading the right oviduct with a cooccurring ipsilateral oviduct adenomatoid tumor was collected and analyzed using pathomorphology and immunohistochemistry.Endometrial clear cell carcinoma cells were distributed in a solid nest,papillary,shoe nail-like,and glandular tube-like distribution.There was infiltrative growth,and tumor cells had clear cytoplasm and obvious nuclear heteromorphism.The cancer tissue was necrotic and mitotic.The cancer tissue invaded the right oviduct.The ipsilateral oviduct also had an adenomatoid tumor.The adenomatoid tumor was arranged in microcapsules lined with flat or cubic cells that were surrounded by smooth muscle tissue.The adenomatoid tumor cells were round in shape.CONCLUSION Clear cell carcinoma of the endometrium can invade the oviduct and occur simultaneously with tubal adenomatoid tumors.Upon pathological diagnosis,one should pay close attention to distinguishing whether an endometrial clear cell carcinoma is invading the oviduct or whether it is accompanied by an adenomatoid tumor of the oviduct.Immunohistochemistry is helpful to differentiate these two disease entities.Endometrial clear cell carcinomas express Napsin-A and P16 and are negative for estrogen receptor and progesterone receptor.The presence of endometrial clear cell carcinoma does not affect the expression of CK and calretinin in adenomatoid tumors.
文摘Objective: To investigate the relation between eosinophilic materials and amyloid P (AP) component in adenomatoid odontogenic tumor (AOT). Methods: The expression of amyloid proteins and basement membrane proteins, including type IV collagen, laminin and heparin sulfate proteoglycan (HSPG), in AOT were analyzed by immunohistochemical method. Results: Most eosinophilic droplets among tumor cells and some epithelial cells showed positive stain for AP component. The immunoreactions of type IV collagen and laminin were only found in blood vessels of this tumor. The tumor cells and eosinophilic materials in duct-like structures were constantly unstained for both amyloid and basement membrane proteins. Present results suggest that the nature and composition of eosinophilic droplets may differ from the eosinophilic layer in ductlike structures. This study first demonstrated that the amyloid-like deposition in AOT is associated with AP component by immunohistochemical method. It supported that AP component may be epithelial origin since the AP immunolocalization was found in tumor cells.
文摘Adenomatoid odontogenic tumor is an unusual benign neoplasm which shares clinical and radiographic characteristics with odontogenic cystic lesions denoting a distinct behavior. This paper reports a case of a 12-year-old boy with a bony consistence tumefaction involving the area from teeth 12 to 17. Radiographically, the lesion was characterized by a well-circum- scribed unilocular radiolucent area displacing maxillary canine, first and second premolars. The final diagnosis was adenomatoid odontogenic tumour. The lesion was enucleated concomitantly with the removal of the canine tooth under general anesthesia. The patient was submitted to orthodontic treatment and has been followed-up for four years. Clinical and radiographic features are discussed in this report.
文摘Benign multicystic peritoneal mesothelioma （BMPM） is a rare tumor that occurs mainly in women in their reproductive age. The pathogenesis of BMPM is unclear and a controversy regarding its neoplastic and reactive nature exists. The biological behavior of BMPM is characterized by its slowly progressive process and high rate of recurrence after surgical resection. In addition this lesion does not present a strong tendency to transform into malignancy. Today approximately 130 cases have been reported. We here report a 62-year-old woman who had diffuse abdominal pain, nausea and vomiting. Physical examination revealed a painful mass in her upper abdomen. She reported a mild dehydration, but the vital signs were normal. Peristaltic rushes, gurgles and highpitched tinkles were audible. Upright plain abdominal film revealed small bowel loops with air-fluid levels. She was diagnosed having an incarcerated incisional hernia that resulted in intestinal obstruction. The patient underwent surgery during which a cystic mass of the right ovary measuring 6 cm × 5 cm × 4 cm, four small cysts of the small bowel （1 cm in diameter） and a cyst at the retroperitoneum measuring 11 cm× 10 cm × 3 cm were found. Complete resection of the lesion was performed. The patient had an uneventful recovery and had no recurrence two years after surgery.
文摘Adenomatoid tumors are the most commonly located .in male and female genital tracts, but they are rarely found in extragenital locations, especially in adrenal glands. These tumors are considered as benign neoplasms of mesothelial derivation, and pathologically show glandular tubules lined by epitheloid cells with intervening trabeculae with a characteristic mixture of adenoidal, angiomatoid, cystic and solid patterns, in addition to focal calcifications and signet-ring like cells frequently.2 Because of the lack of radiological specificity,
文摘Adenomatoid tumors （ATs） are benign neoplasms that most commonly occur in the genital tracts of both male and females. Extragenital ATs are rare and have been reported in the pleura, heart, omentum, the mesentery of the small intestine, pancreas, mediastinal lymph nodes and peri-umbilical skin. 1,2 AT of the adrenal gland is typically an asymptomatic neoplasm with benign behavior, which has been recently recognized as a diagnostic challenge, as it is both rare and can present in such a manner as to suggest a wide range of differential diagnoses. 1,3-8 Here we report a very large AT of the left adrenal gland, which at present appears to be the largest tumor of this type that has ever been reported. It may be the first case of AT associated with a high level of plasma adrenocorticotropic hormone （ACTH）.
