目的:评价鼻丘及下鼻甲划痕法治疗变应性鼻炎(Allergic rhinitis,AR)的临床疗效及安全性。方法:对符合纳入标准的60例AR患者,采用计算机随机法,按照1∶1随机分为治疗组与对照组。治疗组行鼻丘及下鼻甲划痕干预,对照组行等离子筛前神经...目的:评价鼻丘及下鼻甲划痕法治疗变应性鼻炎(Allergic rhinitis,AR)的临床疗效及安全性。方法:对符合纳入标准的60例AR患者,采用计算机随机法,按照1∶1随机分为治疗组与对照组。治疗组行鼻丘及下鼻甲划痕干预,对照组行等离子筛前神经阻断。以视觉模拟评分量表(visual analogue scale,VAS)及鼻眼结膜相关生活质量问卷调查量表(Rhinocoujunctivitis Quality of Life Questionaire)、下鼻甲肿胀程度鼻内镜检查评分作为临床疗效评价指标,以治疗后的出血、感染以及粘连作为安全性评价指标,分别在治疗前、治疗结束后1周及4周对其进行评价。结果:治疗前与治疗后1周、4周比较,VAS总分、RQLQ问卷调查表以及下鼻甲肿胀程度评分均具有显著性差异(P﹤0.05)。治疗后1周与4周对比,各项评分基本稳定,下鼻甲肿胀程度评分呈现下降趋势,且具有显著性差异(P﹤0.05)。安全性评价方面,治疗组有2例患者出现术后出血,对照组有3例患者出现鼻腔黏膜粘连,相应处理后均得到恢复,安全性较高。结论:鼻丘及下鼻甲划痕治疗AR临床疗效显著,安全性较高。展开更多
AIM: To investigate the frequency of anatomical variations in sinonasal region and association of these variations with mucosal diseases. METHODS: The study included 400 cases(191 female and 209 male) who were conside...AIM: To investigate the frequency of anatomical variations in sinonasal region and association of these variations with mucosal diseases. METHODS: The study included 400 cases(191 female and 209 male) who were considered to have preliminary diagnoses of sinonasal pathology and who had paranasal sinus computed tomography(CT) examination in axial plane. Reformatted CT images were studied in all planes.RESULTS: Age range of the patients was 20-83(mean 40.26 ± 14.85). Most commonly detected anatomical variation was Agger nasi cell(74.8%). There was a significant association between clinoid process pneumatization and protrusion of internal carotid arteries and optic nerves into sphenoid sinus(P < 0.001). Besides,the relationships between pterygoid process pneumatization and protrusion of vidian nerve into sphenoid sinus,and between pneumatization of large sphenoid wing and protrusion of maxillary nerves into sphenoid sinus were also significant(P < 0.001). Uncinate bulla and giant ethmoid bulla were found to be significantly associated with sinonasal mucosal diseases(P = 0.004 and P = 0.002,respectively).CONCLUSION: Sinonasal region has a great number of variations,and some of them have been determined to be associated with sinonasal mucosal disease. It is necessary to know that some of these variations are associated with protrusion of significant structures such as carotid artery or optic nerve into the sinus and care should be observed in surgeries on patients carrying these variations.展开更多
文摘目的:评价鼻丘及下鼻甲划痕法治疗变应性鼻炎(Allergic rhinitis,AR)的临床疗效及安全性。方法:对符合纳入标准的60例AR患者,采用计算机随机法,按照1∶1随机分为治疗组与对照组。治疗组行鼻丘及下鼻甲划痕干预,对照组行等离子筛前神经阻断。以视觉模拟评分量表(visual analogue scale,VAS)及鼻眼结膜相关生活质量问卷调查量表(Rhinocoujunctivitis Quality of Life Questionaire)、下鼻甲肿胀程度鼻内镜检查评分作为临床疗效评价指标,以治疗后的出血、感染以及粘连作为安全性评价指标,分别在治疗前、治疗结束后1周及4周对其进行评价。结果:治疗前与治疗后1周、4周比较,VAS总分、RQLQ问卷调查表以及下鼻甲肿胀程度评分均具有显著性差异(P﹤0.05)。治疗后1周与4周对比,各项评分基本稳定,下鼻甲肿胀程度评分呈现下降趋势,且具有显著性差异(P﹤0.05)。安全性评价方面,治疗组有2例患者出现术后出血,对照组有3例患者出现鼻腔黏膜粘连,相应处理后均得到恢复,安全性较高。结论:鼻丘及下鼻甲划痕治疗AR临床疗效显著,安全性较高。
文摘AIM: To investigate the frequency of anatomical variations in sinonasal region and association of these variations with mucosal diseases. METHODS: The study included 400 cases(191 female and 209 male) who were considered to have preliminary diagnoses of sinonasal pathology and who had paranasal sinus computed tomography(CT) examination in axial plane. Reformatted CT images were studied in all planes.RESULTS: Age range of the patients was 20-83(mean 40.26 ± 14.85). Most commonly detected anatomical variation was Agger nasi cell(74.8%). There was a significant association between clinoid process pneumatization and protrusion of internal carotid arteries and optic nerves into sphenoid sinus(P < 0.001). Besides,the relationships between pterygoid process pneumatization and protrusion of vidian nerve into sphenoid sinus,and between pneumatization of large sphenoid wing and protrusion of maxillary nerves into sphenoid sinus were also significant(P < 0.001). Uncinate bulla and giant ethmoid bulla were found to be significantly associated with sinonasal mucosal diseases(P = 0.004 and P = 0.002,respectively).CONCLUSION: Sinonasal region has a great number of variations,and some of them have been determined to be associated with sinonasal mucosal disease. It is necessary to know that some of these variations are associated with protrusion of significant structures such as carotid artery or optic nerve into the sinus and care should be observed in surgeries on patients carrying these variations.
