Small-scale farming accounts for 78% of total agricultural production in Kenya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sol...Small-scale farming accounts for 78% of total agricultural production in Kenya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sold to bring in some income. Timely decisions on farm practices such as farm preparation and planting are critical determinants of the seasonal outcomes. In Kenya, most small-scale farmers have no reliable source of information that would help them make timely and accurate decisions. County governments have extension officers who are mandated with giving farmers advisory services to farmers but they are not able to reach most farmers due to facilitation constraints. The mode and format of sharing information is also critical since it’s important to ensure that it’s timely, well-understood and usable. This study sought to assess access to geospatial derived and other crop production information by farmers in four selected counties of Kenya. Specific objectives were to determine the profile of small-scale farmers in terms of age, education and farm size;to determine the type of information that is made available to them by County and Sub-County extension officers including the format and mode of provision;and to determine if the information provided was useful in terms of accuracy, timeliness and adequacy. The results indicated that over 80% of the farmers were over 35 years of age and over 56% were male. Majority had attained primary education (34%) or secondary education (29%) and most farmers in all the counties grew maize (71%). Notably, fellow farmers were a source of information (71%) with the frequency of sharing information being mostly seasonal (37%) and when information was available (43%). Over 66% of interviewed farmers indicating that they faced challenges while using provided information. The results from the study are insightful and helpful in determining effective ways of providing farmers with useful information to ensure maximum benefits.展开更多
Human pluripotent stem cells(hPSCs), including human embryonic stem cells and human induced pluripotent stem cells, are promising sources for hematopoietic cells due to their unlimited growth capacity and the pluripot...Human pluripotent stem cells(hPSCs), including human embryonic stem cells and human induced pluripotent stem cells, are promising sources for hematopoietic cells due to their unlimited growth capacity and the pluripotency. Dendritic cells(DCs), the unique immune cells in the hematopoietic system, can be loaded with tumor specific antigen and used as vaccine for cancer immunotherapy. While autologous DCs from peripheral blood are limited in cell number, hPSC-derived DCs provide a novel alternative cell source which has the potential for large scale production. This review summarizes recent advances in differentiating hPSCs to DCs through the intermediate stage of hematopoietic stem cells. Step-wise growth factor induction has been used to derive DCs from hPSCs either in suspension cultureof embryoid bodies(EBs) or in co-culture with stromal cells. To fulfill the clinical potential of the DCs derived from hPSCs, the bioprocess needs to be scaled up to produce a large number of cells economically under tight quality control. This requires the development of novel bioreactor systems combining guided EB-based differentiation with engineered culture environment. Hence, recent progress in using bioreactors for hPSC lineage-specific differentiation is reviewed. In particular, the potential scale up strategies for the multistage DC differentiation and the effect of shear stress on hPSC differentiation in bioreactors are discussed in detail.展开更多
In order to ensure overall optimization of the underground metal mine production scale, multidisciplinary design optimization model of production scale which covers the subsystem objective function of income of produc...In order to ensure overall optimization of the underground metal mine production scale, multidisciplinary design optimization model of production scale which covers the subsystem objective function of income of production, safety and environmental impact in the underground metal mine was established by using multidisciplinary design optimization method. The coupling effects from various disciplines were fully considered, and adaptive mutative scale chaos immunization optimization algorithm was adopted to solve multidisciplinary design optimization model of underground metal mine production scale. Practical results show that multidisciplinary design optimization on production scale of an underground lead and zinc mine reflect the actual operating conditions more realistically, the production scale is about 1.25 Mt/a (Lead and zinc metal content of 160 000 t/a), the economic life is approximately 14 a, corresponding coefficient of production profits can be increased to 15.13%, safety factor can be increased to 5.4% and environmental impact coefficient can be reduced by 9.52%.展开更多
The enlarged production scale of underground non-ferrous metal mines is affected by many uncertain factors difficult to describe mathematically with any level of accuracy.The problem can be solved by a synthesis of ar...The enlarged production scale of underground non-ferrous metal mines is affected by many uncertain factors difficult to describe mathematically with any level of accuracy.The problem can be solved by a synthesis of artificial intelligence.Based on the analysis of the major factors affecting the scale of enlarged production,we first interpreted in detail the design principles and structure of the intelligent system.Secondly,we introduced an ANN subsystem.In order to ensure technological and scale efficien- cies of the training samples for ANN,we filtrated the samples with a DEA method.Finally,we trained the intelligent system,which was proved to be very efficient.展开更多
The moderate scale family farm is the future agricultural business entity in China,and the scale of family farm is a key factor affecting its development.With Guigang City in Guangxi as a point for the study,from the ...The moderate scale family farm is the future agricultural business entity in China,and the scale of family farm is a key factor affecting its development.With Guigang City in Guangxi as a point for the study,from the perspective of maximizing income of rural households,this paper uses production function model to calculate the moderate scale of food-production-based family farm at 5.7 ha,and makes policy recommendations.展开更多
Kuwaiti oil production faces a growing challenge in the increasing quantities of produced water generated in the production of oil. The high water cut of the produced fluid from the wells and the high salinity of the ...Kuwaiti oil production faces a growing challenge in the increasing quantities of produced water generated in the production of oil. The high water cut of the produced fluid from the wells and the high salinity of the produced water lead to significant degradation of subsurface equipment, specifically the production tubing. Debris generated through the degradation of the inner part of the tubing becomes a constituent of the scaling that deposits in the tubing and blocks the flow of the production fluid, inducing higher maintenance costs. This paper looks at the characteristics of the scaling in regard to the produced water and outlines the economic impact of the produced water induced degradation of the tubing structure.展开更多
The tobacco growers with the growing area of greater than or equal to 100 mu,have become an important subject of tobacco production in Weng'an County of Guizhou Province. Regulating and developing the production a...The tobacco growers with the growing area of greater than or equal to 100 mu,have become an important subject of tobacco production in Weng'an County of Guizhou Province. Regulating and developing the production and business activities of large-scale tobacco growers, plays an important role in stabilizing tobacco production,reducing costs and increasing efficiency in Weng'an County. Through the field survey of large-scale growers' production activities,this article analyzes the input and output levels,and explores the key factors influencing benefit, in order to provide a basis for further regulating the tobacco growing practices and improving the flue-cured tobacco production benefit.展开更多
Small-scale farmer is defined by the domestic and foreign experts and scholars.They point out that since the fragmentation of production and the diseconomy of scale in small-scale farmer is inconsistent with the chara...Small-scale farmer is defined by the domestic and foreign experts and scholars.They point out that since the fragmentation of production and the diseconomy of scale in small-scale farmer is inconsistent with the characteristics of scale and technology of modern agricultural production,it is necessary to eliminate the adverse effects of existing mode in order to provide theoretical references for the relevant researches.Citrus industry in Shimen County,Hunan Province,China is introduced from the aspects of natural geographical condition and socio-economic benefit.Impact of small-scale production mode on citrus production in Shimen County is discussed.Firstly,blindness of small-scale production is the main reason leading to overproduction of citrus.Secondly,small-scale production mode has limitation on the acceptance of new technologies,restricts the operation of geographical trademark,and constraints the enthusiasm of enterprises in entering the agricultural field.Finally,suggestions are put forward,such as encouraging the circulation of rural land,improving the organization degree of farmers,changing the work function of grass-roots government and perfecting the agricultural financial credit system.展开更多
Ecuador potato crop is family based production system. Potato production has two roles in their economy, the first is providing food for their families and the second is a source of income for the household. However s...Ecuador potato crop is family based production system. Potato production has two roles in their economy, the first is providing food for their families and the second is a source of income for the household. However small scale farmers have limited access to local markets and most of the sales are through intermediates’ who purchase directly in the field at the lowest price possible. Potato production challenges for the small-scale farmers are among others availability of quality potato seed, direct sales, purchase of agrochemical inputs to maintain their crops and lack of education. In 2021, only 4% of potato farmers used certified seed. Potato yield is still low around 16.1 t·ha<sup>-1</sup>, in the last 10 years the total potato cultivated area was reduced by at least 50%. The farmers produce “Bokashi” and other organic fertilizer and these are effective to improve soil fertility and plant health. Homemade bio-pesticides reduce agrochemical pesticides. The Decision Support System (DSS) is a handheld device to control late blight, minimizes fungicide applications and improve fungicide rotation. In 2018 Candidatus Liberibacter solanacearum (Lso), the causal agent of zebra chip, and its vector, the potato psyllid Bactericera cockerelli, together created havoc for farmers and researchers. Promotion of early potato varieties INIAP—Libertad is an alternative to lower the impact of this newest pest.展开更多
Climate change effects have had negative effects on most farmers, both small and large-scale, with weather patterns increasingly becoming unpredictable, such that farmers are unable to plan well for their farming, res...Climate change effects have had negative effects on most farmers, both small and large-scale, with weather patterns increasingly becoming unpredictable, such that farmers are unable to plan well for their farming, resulting in reduced harvests and sometimes losses for farmers. Better availability of information such as weather patterns, suitable crops, nutrient requirements based on soil types and conditions would greatly alleviate these challenges. While geospatial information is being developed and improved continuously by researchers, its accessibility and use by the counties has not been established and cannot be identified as contributing to better crop production outcomes. The aim of this study, therefore, was to assess the awareness and status of geospatial data availability and use for crop production, and the level of the relevant capacities, both human and infrastructural, in selected Counties of Kenya. A survey was conducted in the four counties of Vihiga, Kilifi, Wajir and Nyeri and key informant interviews were conducted with both management and technical County Agricultural Officers, as well as sub-county agricultural extension officers. From the results of the survey, out of the four counties, only one has adequate infrastructure in terms of hard-ware, software and connectivity to conduct useful geospatial data acquisition and processing. While most indicated awareness of the existence of geospatial data, limited resources, low skills and knowledge have restricted any meaningful sourcing of and access to data, with only 38% moderately or highly skilled in acquisition, 48% in processing and 57% in interpretation and use of geospatial data. The study concludes that moderate skills and capacities available within the counties have considerable potential to make use the available geospatial data to inform farmers accordingly and improve their farming outcomes.展开更多
文摘Small-scale farming accounts for 78% of total agricultural production in Kenya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sold to bring in some income. Timely decisions on farm practices such as farm preparation and planting are critical determinants of the seasonal outcomes. In Kenya, most small-scale farmers have no reliable source of information that would help them make timely and accurate decisions. County governments have extension officers who are mandated with giving farmers advisory services to farmers but they are not able to reach most farmers due to facilitation constraints. The mode and format of sharing information is also critical since it’s important to ensure that it’s timely, well-understood and usable. This study sought to assess access to geospatial derived and other crop production information by farmers in four selected counties of Kenya. Specific objectives were to determine the profile of small-scale farmers in terms of age, education and farm size;to determine the type of information that is made available to them by County and Sub-County extension officers including the format and mode of provision;and to determine if the information provided was useful in terms of accuracy, timeliness and adequacy. The results indicated that over 80% of the farmers were over 35 years of age and over 56% were male. Majority had attained primary education (34%) or secondary education (29%) and most farmers in all the counties grew maize (71%). Notably, fellow farmers were a source of information (71%) with the frequency of sharing information being mostly seasonal (37%) and when information was available (43%). Over 66% of interviewed farmers indicating that they faced challenges while using provided information. The results from the study are insightful and helpful in determining effective ways of providing farmers with useful information to ensure maximum benefits.
基金Supported by In part by Florida State University start up fundFlorida State University Research Foundation GAP awardthe partial support from National Science Foundation,No.1342192
文摘Human pluripotent stem cells(hPSCs), including human embryonic stem cells and human induced pluripotent stem cells, are promising sources for hematopoietic cells due to their unlimited growth capacity and the pluripotency. Dendritic cells(DCs), the unique immune cells in the hematopoietic system, can be loaded with tumor specific antigen and used as vaccine for cancer immunotherapy. While autologous DCs from peripheral blood are limited in cell number, hPSC-derived DCs provide a novel alternative cell source which has the potential for large scale production. This review summarizes recent advances in differentiating hPSCs to DCs through the intermediate stage of hematopoietic stem cells. Step-wise growth factor induction has been used to derive DCs from hPSCs either in suspension cultureof embryoid bodies(EBs) or in co-culture with stromal cells. To fulfill the clinical potential of the DCs derived from hPSCs, the bioprocess needs to be scaled up to produce a large number of cells economically under tight quality control. This requires the development of novel bioreactor systems combining guided EB-based differentiation with engineered culture environment. Hence, recent progress in using bioreactors for hPSC lineage-specific differentiation is reviewed. In particular, the potential scale up strategies for the multistage DC differentiation and the effect of shear stress on hPSC differentiation in bioreactors are discussed in detail.
基金Project(2012BAK09B02-05) supported by the National "Twelfth Five-year" Science & Technology Support Plan of China
文摘In order to ensure overall optimization of the underground metal mine production scale, multidisciplinary design optimization model of production scale which covers the subsystem objective function of income of production, safety and environmental impact in the underground metal mine was established by using multidisciplinary design optimization method. The coupling effects from various disciplines were fully considered, and adaptive mutative scale chaos immunization optimization algorithm was adopted to solve multidisciplinary design optimization model of underground metal mine production scale. Practical results show that multidisciplinary design optimization on production scale of an underground lead and zinc mine reflect the actual operating conditions more realistically, the production scale is about 1.25 Mt/a (Lead and zinc metal content of 160 000 t/a), the economic life is approximately 14 a, corresponding coefficient of production profits can be increased to 15.13%, safety factor can be increased to 5.4% and environmental impact coefficient can be reduced by 9.52%.
基金Project 50374005 supported by the National Natural Science Foundation of China
文摘The enlarged production scale of underground non-ferrous metal mines is affected by many uncertain factors difficult to describe mathematically with any level of accuracy.The problem can be solved by a synthesis of artificial intelligence.Based on the analysis of the major factors affecting the scale of enlarged production,we first interpreted in detail the design principles and structure of the intelligent system.Secondly,we introduced an ANN subsystem.In order to ensure technological and scale efficien- cies of the training samples for ANN,we filtrated the samples with a DEA method.Finally,we trained the intelligent system,which was proved to be very efficient.
基金Supported by Scientific Research Project of Guangxi Universities in 2015
文摘The moderate scale family farm is the future agricultural business entity in China,and the scale of family farm is a key factor affecting its development.With Guigang City in Guangxi as a point for the study,from the perspective of maximizing income of rural households,this paper uses production function model to calculate the moderate scale of food-production-based family farm at 5.7 ha,and makes policy recommendations.
文摘Kuwaiti oil production faces a growing challenge in the increasing quantities of produced water generated in the production of oil. The high water cut of the produced fluid from the wells and the high salinity of the produced water lead to significant degradation of subsurface equipment, specifically the production tubing. Debris generated through the degradation of the inner part of the tubing becomes a constituent of the scaling that deposits in the tubing and blocks the flow of the production fluid, inducing higher maintenance costs. This paper looks at the characteristics of the scaling in regard to the produced water and outlines the economic impact of the produced water induced degradation of the tubing structure.
文摘The tobacco growers with the growing area of greater than or equal to 100 mu,have become an important subject of tobacco production in Weng'an County of Guizhou Province. Regulating and developing the production and business activities of large-scale tobacco growers, plays an important role in stabilizing tobacco production,reducing costs and increasing efficiency in Weng'an County. Through the field survey of large-scale growers' production activities,this article analyzes the input and output levels,and explores the key factors influencing benefit, in order to provide a basis for further regulating the tobacco growing practices and improving the flue-cured tobacco production benefit.
文摘Small-scale farmer is defined by the domestic and foreign experts and scholars.They point out that since the fragmentation of production and the diseconomy of scale in small-scale farmer is inconsistent with the characteristics of scale and technology of modern agricultural production,it is necessary to eliminate the adverse effects of existing mode in order to provide theoretical references for the relevant researches.Citrus industry in Shimen County,Hunan Province,China is introduced from the aspects of natural geographical condition and socio-economic benefit.Impact of small-scale production mode on citrus production in Shimen County is discussed.Firstly,blindness of small-scale production is the main reason leading to overproduction of citrus.Secondly,small-scale production mode has limitation on the acceptance of new technologies,restricts the operation of geographical trademark,and constraints the enthusiasm of enterprises in entering the agricultural field.Finally,suggestions are put forward,such as encouraging the circulation of rural land,improving the organization degree of farmers,changing the work function of grass-roots government and perfecting the agricultural financial credit system.
文摘Ecuador potato crop is family based production system. Potato production has two roles in their economy, the first is providing food for their families and the second is a source of income for the household. However small scale farmers have limited access to local markets and most of the sales are through intermediates’ who purchase directly in the field at the lowest price possible. Potato production challenges for the small-scale farmers are among others availability of quality potato seed, direct sales, purchase of agrochemical inputs to maintain their crops and lack of education. In 2021, only 4% of potato farmers used certified seed. Potato yield is still low around 16.1 t·ha<sup>-1</sup>, in the last 10 years the total potato cultivated area was reduced by at least 50%. The farmers produce “Bokashi” and other organic fertilizer and these are effective to improve soil fertility and plant health. Homemade bio-pesticides reduce agrochemical pesticides. The Decision Support System (DSS) is a handheld device to control late blight, minimizes fungicide applications and improve fungicide rotation. In 2018 Candidatus Liberibacter solanacearum (Lso), the causal agent of zebra chip, and its vector, the potato psyllid Bactericera cockerelli, together created havoc for farmers and researchers. Promotion of early potato varieties INIAP—Libertad is an alternative to lower the impact of this newest pest.
文摘Climate change effects have had negative effects on most farmers, both small and large-scale, with weather patterns increasingly becoming unpredictable, such that farmers are unable to plan well for their farming, resulting in reduced harvests and sometimes losses for farmers. Better availability of information such as weather patterns, suitable crops, nutrient requirements based on soil types and conditions would greatly alleviate these challenges. While geospatial information is being developed and improved continuously by researchers, its accessibility and use by the counties has not been established and cannot be identified as contributing to better crop production outcomes. The aim of this study, therefore, was to assess the awareness and status of geospatial data availability and use for crop production, and the level of the relevant capacities, both human and infrastructural, in selected Counties of Kenya. A survey was conducted in the four counties of Vihiga, Kilifi, Wajir and Nyeri and key informant interviews were conducted with both management and technical County Agricultural Officers, as well as sub-county agricultural extension officers. From the results of the survey, out of the four counties, only one has adequate infrastructure in terms of hard-ware, software and connectivity to conduct useful geospatial data acquisition and processing. While most indicated awareness of the existence of geospatial data, limited resources, low skills and knowledge have restricted any meaningful sourcing of and access to data, with only 38% moderately or highly skilled in acquisition, 48% in processing and 57% in interpretation and use of geospatial data. The study concludes that moderate skills and capacities available within the counties have considerable potential to make use the available geospatial data to inform farmers accordingly and improve their farming outcomes.