Previous clinical study showed that aged garlic extract (AGE) has a preventive effect of vascular calcification in patients with coronary artery diseases. It has been reported that vascular smooth muscle cells (VSMC) ...Previous clinical study showed that aged garlic extract (AGE) has a preventive effect of vascular calcification in patients with coronary artery diseases. It has been reported that vascular smooth muscle cells (VSMC) and inflammatory cells including macrophages and lymphocytes migrate to sub-intimal region where atherosclerotic plaques are formed, and VSMC can differentiate into osteoblast-like cells, which are represented by the induction of alkaline phosphatase (ALP). We found that primary human coronary artery smooth muscle cells (HCASMC) showed the increased ALP activity, when cultured in the medium containing ascorbic acid, β-glycerophosphate, dexamethasone (IM), and supplemented with conditioned medium from macrophages (MCM). Then we tested the effect of AGE subdivided fractions and several compounds found in AGE, and then found that ((+)-(2S,3R)-Dehydrodiconiferyl alcohol, a dilignol compound existed in hydrophobic fraction of AGE, inhibited ALP activity in HCASMC.展开更多
The tablet is one of widely used dosage forms for oral route of administration because of convenience of use and short onset of action.Binder is a substance used to bond powder together during the production of a tabl...The tablet is one of widely used dosage forms for oral route of administration because of convenience of use and short onset of action.Binder is a substance used to bond powder together during the production of a tablet.Several compounds have been reported for use as binders including starch,cellulose,povidone and their derivatives[1].Starch from rice grain which is safe and abundant by-product of Thailand agriculture must be heated to prepare binding liquid.Starch treated with alcoholic-alkaline method increased solubility,viscosity and swelling capacity in water at room temperature[2,3].展开更多
The Habo alkaline intrusion, which is located in the south of the Sanjiang area, Yunnan Province, China, is a typical Cenozoic alkaline intrusion. There are a series of small to medium-sized Au and Pb-（Zn） deposits ...The Habo alkaline intrusion, which is located in the south of the Sanjiang area, Yunnan Province, China, is a typical Cenozoic alkaline intrusion. There are a series of small to medium-sized Au and Pb-（Zn） deposits around this intrusion. Those deposits are spatially associated with the Habo alkaline intrusion. （1） The δ^34S values of sulfides from Au deposits range from -1.91‰ to 2.69 ‰, which are similar to those of Pb-（Zn） deposits （-3.82 ‰ to -0.05 ‰） and both indicate a much greater contribution from magma. （2） The Habo alkaline intrusion has relatively homogeneous Pb isotopic compositions with ^206pb/^204pb ranging from 18.608 to 18.761, ^207pb/^204pb from 15.572 to 15.722 and ^20spb/^204pb from 38.599 to 39.110. These Pb isotope ratios are similar to those of Au deposits, whose ^206pb/^204pb range from 18.564 to 18.734, ^20Tpb/^20apb from 15.582 to 15.738 and ^208pb/^204pb from 38.592 to 39.319. Pb ratios in both the intrusion and Au deposits suggest that Pb mainly derived from the depth, probably represents a mixture of mantle and crust. Pb-（Zn） deposits, however, show a decentralized trait, and most of them are similar to that of the alkaline intrusion with ^206pb/^204pb ranging from 18.523 to 18.648, ^207pb/^204pb from 15.599 to 15.802, and ^20spb/^204pb from 38.659 to 39.206. （3） In the plumbotectonic diagram ^20Tpb/^204pb versus ^206pb/^204pb, almost all of Au and Pb-（Zn） deposits have the same projection area with the Habo alkaline intrusion, which indicates that those deposits almost share the same source with the alkaline intrusion. （4） Isotopic age of the Habo alkaline intrusion is 36-33 Ma, which is similar to that of Beiya, whose ore- related alkaline porphyries age is 38-31 Ma and molybdenite Re-Os age is 36.9 Ma. Therefore, along with S-Pb isotope traits, we suggest that the Habo Au and Pb-（Zn） deposits should be typically Ailaoshan-Red RiverCenozoicalkaline-related deposits and ore-forming ages of these deposits should be later than that of the Habo alkaline intrusion.展开更多
Mass spectrometric behaviour of （R） -1- （ 4-alkylphenyl ） alcohols, 1- （4-alkoxylphenyl） alcohols, and 1- （4-alkylthiophenyl） alcohols were studied with the aid of mass-analyzed ion kinetic energy spectrometry...Mass spectrometric behaviour of （R） -1- （ 4-alkylphenyl ） alcohols, 1- （4-alkoxylphenyl） alcohols, and 1- （4-alkylthiophenyl） alcohols were studied with the aid of mass-analyzed ion kinetic energy spectrometry under electron impact ionization. All the title compounds show a tendency to eliminate a water molecule to form alkene ions and undergo an a-cleavago to produce protonated aldehyde ions by the loss of alkyl radicals. Except these two common fragment ions, they also show some different fragmentations due to with or without oxy/thioether-linkage.展开更多
Enantiomers of four amino alcohols were resolved by ion-pair chromatography with (+)-10-camphorsulphonic acid as chiral counter ion. Studies of the influence of the mobile phase composition, the solute structure and t...Enantiomers of four amino alcohols were resolved by ion-pair chromatography with (+)-10-camphorsulphonic acid as chiral counter ion. Studies of the influence of the mobile phase composition, the solute structure and the mobile phase flow-rate on separation are presented. Under the optimized conditions enantiomeric propanolol, norephedrine, metropolol and salbutamol were separated using dichloromethane-1-pentanol (97:3 v/v) as mobile phase on Lichrospher-100-DIOL column.展开更多
Polypropylene superfine fibers or cell porous fibers were prepared from the bi-component blend fibers of polypropylene/easlly hydro-degraded polyester(PP/EHDPET)by alkaline hydrolysis process. EHDPET is a kind of copo...Polypropylene superfine fibers or cell porous fibers were prepared from the bi-component blend fibers of polypropylene/easlly hydro-degraded polyester(PP/EHDPET)by alkaline hydrolysis process. EHDPET is a kind of copolyester that can be rapidly hydro-degraded in the hot alkaline solution. This paper discussed the kinetics of alkaline hydrolysis of EHDPET, and the effect of catalyst, bulk ratio and the content of polypropylene grafted maleic anhydride (PP-g-MAH) on the alkaline hydrolysis process. Meanwhile, the morphological change of the outer surface of blend fibers during this process was also investigated by the technology of scanning electron microscope (SEM).展开更多
In this study, we used a mixture of organic liquid propane-1,3-diol and ionic liquid 1-ethyl-3-methylimidazolium chloride([emim]Cl) as the entrainer to separate tert-butyl alcohol(TBA) + water. We measured the isobari...In this study, we used a mixture of organic liquid propane-1,3-diol and ionic liquid 1-ethyl-3-methylimidazolium chloride([emim]Cl) as the entrainer to separate tert-butyl alcohol(TBA) + water. We measured the isobaric vapor–liquid equilibrium(VLE) for the quaternary system TBA + water + propane-1,3-diol + [emim]Cl at 101.3 kPa, and found the VLE data to be well correlated with the nonrandom two-liquid model. These results show that the mixed solvent of propane-1,3-diol + [emim]Cl can increase the relative volatility of TBA to water and break the azeotropic point. We found no notable synergetic effect between them, and observed that the liquid mixed solvent of propane-1,3-diol and [emim]Cl had lower viscosity than [emim]Cl, which makes it a promising entrainer for separating the TBA + water azeotrope in industrial applications.展开更多
1.Introduction DAFCs offer significant promise for compact electric devices through the consumption of liquid fuels as one of the renewable energy sources,with minimal environmental effects and prominent energy densit...1.Introduction DAFCs offer significant promise for compact electric devices through the consumption of liquid fuels as one of the renewable energy sources,with minimal environmental effects and prominent energy density[1-4].Because of the fuel crossover phenomenon and sluggish kinetics of the alcohol oxidation.展开更多
文摘Previous clinical study showed that aged garlic extract (AGE) has a preventive effect of vascular calcification in patients with coronary artery diseases. It has been reported that vascular smooth muscle cells (VSMC) and inflammatory cells including macrophages and lymphocytes migrate to sub-intimal region where atherosclerotic plaques are formed, and VSMC can differentiate into osteoblast-like cells, which are represented by the induction of alkaline phosphatase (ALP). We found that primary human coronary artery smooth muscle cells (HCASMC) showed the increased ALP activity, when cultured in the medium containing ascorbic acid, β-glycerophosphate, dexamethasone (IM), and supplemented with conditioned medium from macrophages (MCM). Then we tested the effect of AGE subdivided fractions and several compounds found in AGE, and then found that ((+)-(2S,3R)-Dehydrodiconiferyl alcohol, a dilignol compound existed in hydrophobic fraction of AGE, inhibited ALP activity in HCASMC.
文摘The tablet is one of widely used dosage forms for oral route of administration because of convenience of use and short onset of action.Binder is a substance used to bond powder together during the production of a tablet.Several compounds have been reported for use as binders including starch,cellulose,povidone and their derivatives[1].Starch from rice grain which is safe and abundant by-product of Thailand agriculture must be heated to prepare binding liquid.Starch treated with alcoholic-alkaline method increased solubility,viscosity and swelling capacity in water at room temperature[2,3].
文摘The Habo alkaline intrusion, which is located in the south of the Sanjiang area, Yunnan Province, China, is a typical Cenozoic alkaline intrusion. There are a series of small to medium-sized Au and Pb-（Zn） deposits around this intrusion. Those deposits are spatially associated with the Habo alkaline intrusion. （1） The δ^34S values of sulfides from Au deposits range from -1.91‰ to 2.69 ‰, which are similar to those of Pb-（Zn） deposits （-3.82 ‰ to -0.05 ‰） and both indicate a much greater contribution from magma. （2） The Habo alkaline intrusion has relatively homogeneous Pb isotopic compositions with ^206pb/^204pb ranging from 18.608 to 18.761, ^207pb/^204pb from 15.572 to 15.722 and ^20spb/^204pb from 38.599 to 39.110. These Pb isotope ratios are similar to those of Au deposits, whose ^206pb/^204pb range from 18.564 to 18.734, ^20Tpb/^20apb from 15.582 to 15.738 and ^208pb/^204pb from 38.592 to 39.319. Pb ratios in both the intrusion and Au deposits suggest that Pb mainly derived from the depth, probably represents a mixture of mantle and crust. Pb-（Zn） deposits, however, show a decentralized trait, and most of them are similar to that of the alkaline intrusion with ^206pb/^204pb ranging from 18.523 to 18.648, ^207pb/^204pb from 15.599 to 15.802, and ^20spb/^204pb from 38.659 to 39.206. （3） In the plumbotectonic diagram ^20Tpb/^204pb versus ^206pb/^204pb, almost all of Au and Pb-（Zn） deposits have the same projection area with the Habo alkaline intrusion, which indicates that those deposits almost share the same source with the alkaline intrusion. （4） Isotopic age of the Habo alkaline intrusion is 36-33 Ma, which is similar to that of Beiya, whose ore- related alkaline porphyries age is 38-31 Ma and molybdenite Re-Os age is 36.9 Ma. Therefore, along with S-Pb isotope traits, we suggest that the Habo Au and Pb-（Zn） deposits should be typically Ailaoshan-Red RiverCenozoicalkaline-related deposits and ore-forming ages of these deposits should be later than that of the Habo alkaline intrusion.
文摘Mass spectrometric behaviour of （R） -1- （ 4-alkylphenyl ） alcohols, 1- （4-alkoxylphenyl） alcohols, and 1- （4-alkylthiophenyl） alcohols were studied with the aid of mass-analyzed ion kinetic energy spectrometry under electron impact ionization. All the title compounds show a tendency to eliminate a water molecule to form alkene ions and undergo an a-cleavago to produce protonated aldehyde ions by the loss of alkyl radicals. Except these two common fragment ions, they also show some different fragmentations due to with or without oxy/thioether-linkage.
文摘Enantiomers of four amino alcohols were resolved by ion-pair chromatography with (+)-10-camphorsulphonic acid as chiral counter ion. Studies of the influence of the mobile phase composition, the solute structure and the mobile phase flow-rate on separation are presented. Under the optimized conditions enantiomeric propanolol, norephedrine, metropolol and salbutamol were separated using dichloromethane-1-pentanol (97:3 v/v) as mobile phase on Lichrospher-100-DIOL column.
文摘Polypropylene superfine fibers or cell porous fibers were prepared from the bi-component blend fibers of polypropylene/easlly hydro-degraded polyester(PP/EHDPET)by alkaline hydrolysis process. EHDPET is a kind of copolyester that can be rapidly hydro-degraded in the hot alkaline solution. This paper discussed the kinetics of alkaline hydrolysis of EHDPET, and the effect of catalyst, bulk ratio and the content of polypropylene grafted maleic anhydride (PP-g-MAH) on the alkaline hydrolysis process. Meanwhile, the morphological change of the outer surface of blend fibers during this process was also investigated by the technology of scanning electron microscope (SEM).
基金supported by the Innovation Fund of Tianjin University (No. 2010XJ-0022)
文摘In this study, we used a mixture of organic liquid propane-1,3-diol and ionic liquid 1-ethyl-3-methylimidazolium chloride([emim]Cl) as the entrainer to separate tert-butyl alcohol(TBA) + water. We measured the isobaric vapor–liquid equilibrium(VLE) for the quaternary system TBA + water + propane-1,3-diol + [emim]Cl at 101.3 kPa, and found the VLE data to be well correlated with the nonrandom two-liquid model. These results show that the mixed solvent of propane-1,3-diol + [emim]Cl can increase the relative volatility of TBA to water and break the azeotropic point. We found no notable synergetic effect between them, and observed that the liquid mixed solvent of propane-1,3-diol and [emim]Cl had lower viscosity than [emim]Cl, which makes it a promising entrainer for separating the TBA + water azeotrope in industrial applications.
基金supported by the NSF of China(21971143)the 111 Project(D20015)+3 种基金the project of Hubei Three Gorges Laboratory,the postdoctoral innovation research foundation of Hubei Province(287189)the NSF of Hubei Province(2020CFB686)ITOYMR in the Higher Education Institutions of Hubei Province(T201904)the opening foundation from the State Key Laboratory of Inorganic Synthesis and Preparative Chemistry(Jilin University,2023-29)
文摘1.Introduction DAFCs offer significant promise for compact electric devices through the consumption of liquid fuels as one of the renewable energy sources,with minimal environmental effects and prominent energy density[1-4].Because of the fuel crossover phenomenon and sluggish kinetics of the alcohol oxidation.
基金Special Fund for Forestry Industry Research in the Public Interest(20120480306)The 12th Five-year Plan of Science and Technology subject(2012BAD24B04)
