An efficient isomerization of alkynyl ketones to (E,E)-diene ketones was developed. The reaction catalyzed by 20 mol% triphenylphosphine in aqueous media gave the desired products in good yields.
A stereoselective and effective method for the synthesis of vinyl thioethers has been developed.This method is based on the Michael addition of ethanethiol to various alkynyl ketones using 10 mol%of tributylphosphine ...A stereoselective and effective method for the synthesis of vinyl thioethers has been developed.This method is based on the Michael addition of ethanethiol to various alkynyl ketones using 10 mol%of tributylphosphine as catalyst.Most of alkynyl ketones react with ethanethiol in this system to yield mainly Z-isomer of vinyl thioether adducts,only in one case mainly E-isomer of vinyl thioether adducts was observed.展开更多
Fluorinated alkynyl ketones react with hydrazine to give fluorinated pyrazols in good to excellent yields with Au（I） as catalyst. All the reactions were carried out at room temperature with excellent regioselectivity.
文摘An efficient isomerization of alkynyl ketones to (E,E)-diene ketones was developed. The reaction catalyzed by 20 mol% triphenylphosphine in aqueous media gave the desired products in good yields.
基金support from National Natural Science Foundation of China(No.30973609)
文摘A stereoselective and effective method for the synthesis of vinyl thioethers has been developed.This method is based on the Michael addition of ethanethiol to various alkynyl ketones using 10 mol%of tributylphosphine as catalyst.Most of alkynyl ketones react with ethanethiol in this system to yield mainly Z-isomer of vinyl thioether adducts,only in one case mainly E-isomer of vinyl thioether adducts was observed.
基金Project sup ported by the the National Natural Science Foundation of China （Nos. 20532040 and 20772145）.
文摘Fluorinated alkynyl ketones react with hydrazine to give fluorinated pyrazols in good to excellent yields with Au（I） as catalyst. All the reactions were carried out at room temperature with excellent regioselectivity.
