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Allium自膨胀覆膜支架治疗复杂性输尿管狭窄的远期安全性及有效性评价
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作者 李茂 张国庆 +1 位作者 梁思敏 李杰 《重庆医科大学学报》 CAS CSCD 北大核心 2024年第6期765-770,共6页
目的:评估Allium自膨胀覆膜支架治疗复杂性输尿管狭窄的长期疗效和安全性。方法:回顾性分析2020年4月至2021年12月,在重庆医科大学第一附属医院泌尿外科置入Allium自膨胀覆膜支架的输尿管狭窄患者临床资料及长期随访结果。对符合正态分... 目的:评估Allium自膨胀覆膜支架治疗复杂性输尿管狭窄的长期疗效和安全性。方法:回顾性分析2020年4月至2021年12月,在重庆医科大学第一附属医院泌尿外科置入Allium自膨胀覆膜支架的输尿管狭窄患者临床资料及长期随访结果。对符合正态分布的关键性指标行配对样本T检验,对不符合正态分布指标行相关样本非参数检验。结果:通过排除标准严格选择后,本研究共纳入22例通过内镜下Allium自膨胀覆膜支架置入的输尿管狭窄患者。平均年龄为(48.3±10.6)岁,中位随访时间为36.5个月。手术时间为86(35~270)min,围术期没有严重并发症发生。随访结果显示,有17例(77.3%)覆膜支架始终保持在位且通畅,其中16例随访终点时肾积水消失,1例由术前重度积水改善为轻度积水。1例患者因肾积水无法缓解选择拔出支架后行机器人输尿管重建手术。4例患者因并发结石取出支架,其中1例患者取出支架后无肾积水,1例患者积水减轻,其余2例患者仍为重度积水,但尿液排泄通畅无腰痛症状。随访期间患者未见明显手术并发症及严重支架管相关症状。患者的术前平均血肌酐浓度为(103.6±31.1)μmol/L,终末随访时血肌酐浓度下降为(102.2±27.7)μmol/L,差异无统计学意义(P=0.942)。最大肾积水宽度术前为(5.9±2.1)cm,术后为(1.7±1.2)cm,差异有统计学意义(P=0.000)。与术后相比,终末最大肾积水宽度为(0.35±0.25)cm,差异有统计学意义(P=0.001)。结论:Allium自膨胀覆膜支架管在复杂输尿管狭窄治疗的长期观察中能有效改善患者肾积水。支架管症状、疼痛、感染等并发症保持较低的发生率,并且可长期留置,减少患者更换支架的频率。 展开更多
关键词 输尿管狭窄 内镜治疗 allium覆膜支架
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Flower morphology of Allium(Amaryllidaceae)and its systematic significance
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作者 Ju Eun Jang Shukherdorj Baasanmunkh +5 位作者 Nudkhuu Nyamgerel Seung-Yoon Oh Jun-Ho Song Ziyoviddin Yusupov Komijlon Tojibaev Hyeok Jae Choi 《Plant Diversity》 SCIE CAS CSCD 2024年第1期3-27,共25页
Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,w... Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,we examined and measured the floral characteristics of 87 accessions of 74 Allium taxa(belonging to 30 sections and nine subgenera)from Central to Eastern Asian countries.We then examined the taxonomic relationships between select flower characteristics and a phylogenetic tree based on ITS sequences.Our results confirm that floral morphology provides key taxonomic information to assess species delimitation in Allium.We found that perianth color is an important characteristic within the subg.Melanocrommyum,Polyprason,and Reticulatobulbosa.In subg.Allium,Cepa,and Rhizirideum,significant characteristics include ovary shape,perianth shape,and inner tepal apex.For species in subg.Angunium,the key taxonomic character is ovule number(only one ovule in per locule).In the subg.Allium,Cepa,Polyprason,and Reticulatobulbosa,which belong to the third evolutionary line of Allium,hood-like appendages occur in the ovary,although these do not occur in subg.Rhizirideum.Our results also indicated that the flower morphology of several species in some sections are not clearly distinguished,e.g.,sect.Sacculiferum(subg.Cepa)and sect.Tenuissima(subg.Rhizirideum).This study provides detailed photographs and descriptions of floral characteristics and information on general distributions,habitats,and phenology of the studied taxa. 展开更多
关键词 allium Flower morphology Pistil character Statistical analysis Significant characteristic Species level
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Integrating high-volume molecular and morphological data into the evolutionary studies of Allium
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作者 Xing-Jin He 《Plant Diversity》 SCIE CAS CSCD 2024年第1期1-2,共2页
The genus Allium(Amaryllidaceae),which includes economically important plants such as onions,garlic,and leeks,is one of the most species-rich and diverse genera of monocotyledon plants in the Northern Hemisphere(Govae... The genus Allium(Amaryllidaceae),which includes economically important plants such as onions,garlic,and leeks,is one of the most species-rich and diverse genera of monocotyledon plants in the Northern Hemisphere(Govaerts et al.,2021),with approximately 1000 species.The evolution of Allium is characterized by ecological diversification,with most species preferring open. 展开更多
关键词 SPECIES EVOLUTIONARY allium
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Phylotranscriptomic discordance is best explained by incomplete lineage sorting within Allium subgenus Cyathophora and thus hemiplasy accounts for interspecific trait transition
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作者 Zengzhu Zhang Gang Liu Minjie Li 《Plant Diversity》 SCIE CAS CSCD 2024年第1期28-38,共11页
The transition of traits between genetically related lineages is a fascinating topic that provides clues to understanding the drivers of speciation and diversification.Much can be learned about this process from phylo... The transition of traits between genetically related lineages is a fascinating topic that provides clues to understanding the drivers of speciation and diversification.Much can be learned about this process from phylogeny-based trait evolution.However,such inference is often plagued by genome-wide gene-tree discordance(GTD),mostly due to incomplete lineage sorting(ILS)and/or introgressive hybridization,especially when the genes underlying the traits appear discordant.Here,by collecting transcriptomes,whole chloroplast genomes(cpDNA),and population genetic datasets,we used the coalescent model to turn GTD into a source of information for ILS and employed hemiplasy to explain specific cases of apparent“phylogenetic discordance”between different morphological traits and probable species phylogeny in the Allium subg.Cyathophora.Both concatenation and coalescence methods consistently showed the same phylogenetic topology for species tree inference based on single-copy genes(SCGs),as supported by the KS distribution.However,GTD was high across the genomes of subg.Cyathophora:~27%e38.9%of the SCG trees were in conflict with the species tree.Plasmid and nuclear incongruence was also present.Our coalescent simulations indicated that such GTD was mainly a product of ILS.Our hemiplasy risk factor calculations supported that random fixation of ancient polymorphisms in different populations during successive speciation events along the subg.Cyathophora phylogeny may have caused the character transition,as well as the anomalous cpDNA tree.Our study exemplifies how phylogenetic noise can be transformed into evolutionary information for understanding character state transitions along species phylogenies. 展开更多
关键词 Hemiplasy Multispecies coalescence Lineage sorting Gene tree discordance Phylotranscriptomics allium subg.Cyathophora
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The Beneficial Effects of Components of Garlic (Allium sativum L.) in the Poultry Industry
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作者 Alejandra Meza-Rios Gilberto Velazquez-Juarez +9 位作者 Inkar Castellanos-Huerta Rocio Ivette Lopez-Roa Luis A. Anguiano-Sevilla Xochitl Hernanez-Velasco Xochitl Hernanez-Velasco Saeed El-Ashram Ebtsam Al-Olayan Billy Hargis Guillermo Tellez-Isaias Adelaida Sara Minia Zepeda-Morales 《Food and Nutrition Sciences》 CAS 2024年第1期27-57,共31页
Plant-based antimicrobial agents are readily available, cost-effective, and exhibit low toxicity, making them promising alternatives in combatting microbial infections. Among these plants, garlic (Allium sativum) stan... Plant-based antimicrobial agents are readily available, cost-effective, and exhibit low toxicity, making them promising alternatives in combatting microbial infections. Among these plants, garlic (Allium sativum) stands out for its traditional medicinal use in effectively combating various microorganisms. In the poultry industry, preventing avian virus and bacterial infections is paramount for chicken husbandry. However, using conventional drugs poses potential risks to human health. Garlic, a widely used Asian plant in traditional medicine for various pathologies, has shown potential as an herbal prophylactic remedy against viral and bacterial infections. Recently, researchers explored garlic and its derivatives as a scientific strategy in veterinary practices for diverse purposes, such as improving poultry production characteristics and acting as antibiotic growth promoters. This comprehensive review delves into garlic and its derivatives as preventive and corrective treatments for viral diseases in laying hens and broilers. The paper highlights their potential effectiveness and safety as a natural means to enhance poultry health and welfare while mitigating the risks associated with conventional drug usage in the food industry. 展开更多
关键词 GARLIC ANTIVIRAL VETERINARY CHICKENS allium sativum
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Physicochemical and Biochemical Characterization, Total Phenolic and Energy Value from Bulbs of Different Onion (Allium cepa L.) Varieties in Senegal
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作者 Ndeye Adiara Ndiaye Lahat Niang +1 位作者 Modou Dieng Ndeye Coumba Kane Touré 《Food and Nutrition Sciences》 CAS 2024年第2期129-139,共11页
The purpose of this study is to investigate the physicochemical properties of some local varieties of onion (Allium cepa L.) and compare them with an imported variety, all collected in May 2021. Proteins, reducing sug... The purpose of this study is to investigate the physicochemical properties of some local varieties of onion (Allium cepa L.) and compare them with an imported variety, all collected in May 2021. Proteins, reducing sugars, lipids, and polyphenol content were estimated according to the AFNOR standardized methods. The determination of calcium, magnesium, iron, sodium, potassium and phosphorus was performed by atomic absorption spectrophotometer coupled with a CCD detector. The results highlighted an average acidity of 0.377% ± 0.002% lower than the value of the imported variety which is 0.520% ± 0.001%. Local varieties have a pH ranging from 6.35 ± 0.003 to 6.42 ± 0.004, while the variety has a pH of 6.36 ± 0.003. The ash and dry matter contents vary respectively from 4.788% ± 0.004% to 8.253% ± 0.003% and 7.945% ± 0.021% to 11.945% ± 0.007% for the local varieties. Moreover, the imported one has ash and dry matter contents of 5.175% ± 0.007% and 10.035% ± 0.021% respectively. The results show that the protein, reducing sugar and lipid contents in the local onion varieties vary respectively from 2.815 ± 0.000 to 15.634 ± 0.001 g·100 g<sup>-1</sup>;4.691 ± 0.001 to 12.596 ± 0.002 g·100 g<sup>-1</sup> and 0.006 ± 0.001 to 0.050 ± 0.057 g·100 g<sup>-1</sup>. Furthermore, the imported variety has a protein, reducing sugar and lipid content of 5.649 ± 0.002;8.565 ± 0.002 g·100 g<sup>-1</sup> and 0.011 ± 0.010 g·100 g<sup>-1</sup> respectively. The maximum levels of total polyphenols are obtained in the imported variety, Bellani and Gandiol, respectively 9.973 ± 0.001, 4.535 ± 0.002, and 3.425 ± 0.006 mg EAG/g of dry matter. The local varieties have a significant calorific intake of between 35.451 ± 0.001 and 112.980 ± 0.003 kcal·100 g<sup>-1</sup> compared to the imported one with an energy value of 56.953 ± 0.001 kcal·100 g<sup>-1</sup> of dry matter. The bulbs of different onion varieties studied have a fairly high content of mineral elements. The potassium content of local varieties is between 502.16 ± 0.06 mg·100 g<sup>-1</sup> and 582.77 ± 0.04 mg·100 g<sup>-1</sup> while the imported variety has a content of 536.62 ± 1.30 mg·100 g<sup>-1</sup>. They note that the local varieties have a better calcium content (249.75 ± 0.07 to 434.20 ± 0.57 mg·100 g<sup>-1</sup>) and magnesium (142.15 ± 0.07 to 162.60 ± 0.42 mg·100 g<sup>-1</sup>) than the imported variety (229.58 ± 0.04 mg·100 g<sup>-1</sup>) except for the varieties White Grano (228.29 ± 0.01 mg·100 g<sup>-1</sup>) and Rouge Amposta (117.00 ± 0.42 mg·100 g<sup>-1</sup>) respectively. These results reveal that Gandiol, Dayo and Orient F1 are nutritionally found better due to their higher antioxidant property, proteins, carbohydrates, and reducing sugar and should be included in diets to supplement our daily allowance needed by the body. 展开更多
关键词 allium cepa L. CHARACTERIZATION PHYSICOCHEMICAL BIOCHEMISTRY Total Phenolic
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Allium球部尿道支架用于男性复发性复杂尿道狭窄的治疗体会 被引量:1
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作者 刘菲 陈跃东 曾彦恺 《微创泌尿外科杂志》 2023年第2期106-109,共4页
目的:初步评价置入Allium球部尿道支架治疗男性复发性复杂尿道狭窄的疗效及并发症。方法:回顾性分析2020年2月至2022年12月厦门大学附属第一医院收治的外伤骨盆骨折术后患者15例,其中14例曾行尿道成形术,1例行尿道狭窄内切开术2次,8例... 目的:初步评价置入Allium球部尿道支架治疗男性复发性复杂尿道狭窄的疗效及并发症。方法:回顾性分析2020年2月至2022年12月厦门大学附属第一医院收治的外伤骨盆骨折术后患者15例,其中14例曾行尿道成形术,1例行尿道狭窄内切开术2次,8例有多次尿道狭窄球囊扩张病史。采用全麻下经尿道输尿管镜下球囊扩张尿道狭窄后置入Allium支架,7例患者经会阴部固定支架,8例未行固定。术后第一天夹闭膀胱造瘘管,开始观察患者的排尿情况,并行骨盆平片了解Allium支架位置。门诊随访尿流率,观察疗效及并发症发生情况。结果:13例患者术后第1天即可排尿,8例患者术后4d~3个月因支架发生远端移位进行调整或更换新支架,其中包括2例之前已行支架固定的患者,2例出现排尿不适,1例发生明显肉眼血尿,4例术后息肉堵塞支架,1例支架内膜多发细小结石。留置时间为2~11个月,平均5.5个月,平均随访11.9个月(2~24个月),术后最大尿流率(Qmax)平均值为10.6ml/s,排尿满意者8例(53.3%)。结论:Allium球部尿道支架治疗失败的主要原因与术后支架移位有关,可临时用于治疗尿道成形术后复发而不愿或不适宜手术的患者。 展开更多
关键词 allium球部尿道支架 男性 尿道狭窄 手术
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Production of autotetraploid plants by in vitro chromosome engineering in Allium hirtifolium 被引量:1
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作者 Nasrin Farhadi Jaber Panahandeh +1 位作者 Alireza Motallebi-Azar Sam Mokhtarzadeh 《Horticultural Plant Journal》 SCIE CAS CSCD 2023年第5期986-998,共13页
Persian shallot has been propagated vegetatively through daughter bulbs and has a narrow genetic base.In the present study,to create genetic diversity in terms of ploidy level,the effects of in vitro polyploidization ... Persian shallot has been propagated vegetatively through daughter bulbs and has a narrow genetic base.In the present study,to create genetic diversity in terms of ploidy level,the effects of in vitro polyploidization were investigated on morphological,physiological and phytochemical traits.Different colchicine treatments(0,0.3%,0.5% and 0.7% concentrations)for 24,36 and 48 h and oryzalin treatments(0,0.001%,0.002% and 0.004% concentrations)for 4,6 and 8 h were used.A sterile basal plate of bulbs was used for the induction of polyploidy in liquid and solid media.After obtaining plantlets,root tip chromosomes were counted for the determination of ploidy levels.Flow cytometry was performed to confirm the chromosome counting results.The regenerated diploid and tetraploid plantlets were transferred to ex vitro conditions.Colchicine and oryzalin were both successful in inducing polyploids and the polyploids induced were tetraploids and mixoploids.The highest induction of polyploidy was obtained in solid media using 0.5%(w/v)colchicine for 36 h(35.0% polyploidy induction)and in 0.001%(w/v)Oryzalin for 8 h(45.5% polyploidy induction).Differences in plantlet height and weight,bulblet weight,density,stomatal width and length,and chlorophyll content were observed between tetraploid and diploid plants.Chromosome duplication,as a result of tetraploid induction,significantly influenced the antioxidant content and enzyme activities.The results showed that total phenolic content,allicin,and antioxidant capacity were significantly higher in the tetraploid plantlets than that in the diploid plantlets.SRAP loci polymorphisms indicated that the 12 autotetraploid plants(with high allicin content)had different genotypes from the parental diploid plant.Besides,in vitro polyploidy induction not only duplicated chromosomes but also altered the DNA sequence in Allium hirtifolium.In vitro induction of tetraploids in A.hirtifolium can be a reliable way to obtain suitable plant material for breeding programs to generate new genotypic variations. 展开更多
关键词 Persian shallot allium hirtifolium POLYPLOIDY COLCHICINE ORYZALIN Molecular marker
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Characteristics and expression of the TCP transcription factors family in Allium senescens reveal its potential roles in drought stress responses 被引量:1
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作者 XIAOHONG FU JIE ZHAO +5 位作者 DANDAN CAO CHENGXING HE ZIYI WANG YIBEI JIANG JIANFENG LIU GUIXIA LIU 《BIOCELL》 SCIE 2023年第4期905-917,共13页
Allium senescens,is an important economic and ecological grassland plant with drought-resistant characteristics.A TCP protein transcription factor is important in the regulation of plant development and adverse respon... Allium senescens,is an important economic and ecological grassland plant with drought-resistant characteristics.A TCP protein transcription factor is important in the regulation of plant development and adverse responses.However,the mechanism by which TCP transcription functions in drought resistance in Allium senescens is still not clear.Here,we obtained a total of 190,305 transcripts with 115,562 single gene clusters based on RNA-Seq sequencing of Allium senescens under drought stress.The total number of bases was 97,195,096 bp,and the average length was 841.06 bp.Furthermore,we found that there were eight genes of the TCP family that showed an upregulated expression trend under drought stress in Allium senescens.We carried out an investigation to determine the evolution and function of the AsTCP family and how they produce an effect in drought resistance.The 14 AsTCP genes were confirmed and divided into class I and class II containing CIN and CYC/TBI subfamilies,respectively.We also found that the expression of AsTCP17 was remarkably upregulated with drought treatment.Besides,the transformation of AsTCP17 in Arabidopsis revealed that the protective enzymes,namely polyphenol oxidase(POD)and superoxide dismutase(SOD),were increased by 0.4 and 0.8 times,respectively.Chlorophyll content was also increased,while the H2O2 and malondialdehyde(MDA)contents were decreased.Staining assays with 3,3′-diaminobenzidine(DAB)also suggested that the AsTCP17 downregulates reactive oxygen species(ROS)accumulation.In addition,overexpression of the AsTCP17 affected the accumulation of drought-related hormones in plants,and the synthesis of ABA.The expression of AtSVP and AtNCED3,related ABA synthesis pathway genes,indicated that the level of expression of AtSVP and AtNCED3 was obviously enhanced,with the overexpression of line 6 showing a 20.6-fold and 7.0-fold increase,respectively.Taken together,our findings systematically analyze the AsTCPs family at the transcriptome expression level in Allium senescens,and we also demonstrated that AsTCP17 protein,as a positive regulator,was involved in drought resistance of Allium senescens.In addition,our research contributes to the comprehensive understanding of the drought stress defense mechanism in herbaceous plants. 展开更多
关键词 allium senescens Drought stress TCP transcription factor ABA synthesis pathway
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Allium覆膜支架在泌尿外科中的临床应用
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作者 明映江 舒铁环 向志钢 《临床医学进展》 2023年第12期20336-20341,共6页
输尿管支架是泌尿外科的重要武器,可用于上尿路引流、治疗输尿管狭窄、解除尿路梗阻等方面。随着医疗技术的发展及科技的进步,新型输尿管支架层出不穷,比如Resonance支架、尿道金属支架、Allium覆膜支架等,其中以Allium覆膜支架为代表... 输尿管支架是泌尿外科的重要武器,可用于上尿路引流、治疗输尿管狭窄、解除尿路梗阻等方面。随着医疗技术的发展及科技的进步,新型输尿管支架层出不穷,比如Resonance支架、尿道金属支架、Allium覆膜支架等,其中以Allium覆膜支架为代表的新型输尿管支架在泌尿外科治疗中得到广泛的应用。本文就Allium覆膜支架在泌尿外科的临床应用中展开论述。 展开更多
关键词 allium覆膜支架 输尿管狭窄 尿道狭窄 前列腺增生 输尿管阴道瘘
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Allium支架植入后移位的原因分析与处理方法探讨
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作者 崔哲铭 许长宝 《智慧健康》 2023年第16期49-52,61,共5页
目的分析Allium支架移位的原因并探讨其处理方法。方法回顾性分析本院2例行Allium支架置入术后发生覆膜支架向上移位患者的临床资料和随访结果。结果2例患者术后均出现Allium支架移位,且均有结核病史。第一位患者累计放置3次Allium支架... 目的分析Allium支架移位的原因并探讨其处理方法。方法回顾性分析本院2例行Allium支架置入术后发生覆膜支架向上移位患者的临床资料和随访结果。结果2例患者术后均出现Allium支架移位,且均有结核病史。第一位患者累计放置3次Allium支架,并成功运用球囊辅助调整1次Allium支架位置,前2次留置Allium支架后均出现移位,第3次改进留置Allium支架手术方法,术后3个月未发现移位且肾积水明显减轻,现在进行规律复查;第二位患者放置Allium支架7个月后出现移位,球囊辅助调整Allium支架位置后留置2根双J管,留置1月后复查肾积水减轻,现双J管已拔除。结论Allium支架是治疗输尿管狭窄的有效方法,移位是其常见并发症,多发于UPJO及UVJO患者,但减少肾盂段长度和增加膀胱段长度可降低覆膜支架移位的风险;结核可能是Allium支架移位的危险因素;对于早期轻度的Allium支架移位患者,临床医生应积极尝试手术方法来调整支架位置。 展开更多
关键词 allium支架 输尿管狭窄 覆膜支架移位
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Allium覆膜输尿管支架长期留置治疗输尿管狭窄的疗效分析
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作者 李帅 赵江 +4 位作者 朱景振 伍应兵 张远宁 孙碧韶 易善红 《现代泌尿外科杂志》 CAS 2023年第11期942-946,951,共6页
目的分析采用Allium覆膜输尿管支架长期留置治疗输尿管狭窄的安全性及有效性。方法回顾性分析2020年8月—2022年12月在陆军军医大学第二附属医院因输尿管狭窄行内镜下Allium覆膜输尿管支架置入术治疗的患者的临床资料,记录患者手术情况... 目的分析采用Allium覆膜输尿管支架长期留置治疗输尿管狭窄的安全性及有效性。方法回顾性分析2020年8月—2022年12月在陆军军医大学第二附属医院因输尿管狭窄行内镜下Allium覆膜输尿管支架置入术治疗的患者的临床资料,记录患者手术情况及术后随访期内的不良反应事件发生情况,对患者术前和术后1、3、6、12个月的血肌酐、血尿素氮、肾小球滤过率(GFR)、超声下肾盂宽度等数据进行比较。结果共纳入52例患者,其输尿管狭窄长度1.1(0.7~2.0)cm。所有患者均手术顺利,手术时间82.5(70~114)min,术中出血量20(10~20)mL;术后住院天数1(1~2)d;术后随访时间(13.2±7.8)个月,其中有14例患者发生支架移位,5例患者出现结石阻塞支架管,7例患者出现偶尔活动后血尿,9例患者出现间歇性腰腹部疼痛,1例患者出现反复泌尿系感染;术后1、3、6、12个月的血肌酐、血尿素氮、超声下肾盂宽度较术前均明显降低,GFR均明显升高。结论Allium覆膜输尿管支架长期留置治疗输尿管狭窄疗效可观,但支架移位发生率高,应引起重视。 展开更多
关键词 allium覆膜输尿管支架 长期留置 输尿管狭窄 安全性 有效性
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Radioprotective Potencies of Allium Cepa Extract (ACE) against Radiation-Induced Hepatoxicity in Wistar Rats
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作者 Sylvester Kelechi Kenneth Okeke Francisca Nneka +1 位作者 Agwu Kenneth Kalu Attah Okwudili Joseph 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2023年第3期59-83,共25页
Background and Purpose: All types of ionizing radiations generate ions which can lead to the formation of free radicals and reactive oxygen species (ROS). Excess production of free radicals or decrease in antioxidants... Background and Purpose: All types of ionizing radiations generate ions which can lead to the formation of free radicals and reactive oxygen species (ROS). Excess production of free radicals or decrease in antioxidants level leads to oxidative stress. It is a harmful process that induces damage to cell structures, lipids, proteins, RNA and DNA which leads to a number of diseases. The aim of this study is to examine the effect of plant extract (Allium Cepa Extract (ACE)) on the kidney of wistar rats exposed to radiation using and assaying some biochemical enzymes. Material and Method: 60 wistar rats weighing 170 ± 20 g were equally divided into six groups for the study. Group 1 (control): neither received ACE nor irradiation. Group 2 (ACE): received 1000 mg/Kg b.wt of ACE. Group 3 (4 Gy-Irradiated): were exposed to 4 Gy TBI on day 14. Group 4 (6 Gy-Irradiated): were exposed to 6 Gy TBI on day 14. Group 5 (ACE + 4 Gy): were treated with 1000 mg/Kg b.wt of ACE once daily for twenty-eight days but exposed to 4 Gy TBI on day 14. Group 6 (ACE + 6 Gy): were treated with 1000 mg/Kg b.wt of ACE once daily for twenty-eight days but exposed to 6 Gy TBI on day 14. All the groups received distilled water and feed ad libitum during the acclimatization and experimental periods. Four animals in each group were sacrificed 24 h after irradiation and the 4 remaining animals were sacrificed on day 29 for biochemical assay and histopathological evaluation, the statistical analysis was done using one-way analysis of variance (ANOVA) on the data editor SPSS version 28. Results: From the biochemical enzymes, the level of Malondialdehyde (MDA) in group 2 when compared to group 1 was almost the same, which was not statically significant with (p > 0.05), but groups 3 and 4 show a significant increase in the level of MDA with (p < 0.05) while group 5 and 6 showed no significant increase in MAD with (p > 0.05). The other enzymes like SOD, CAT, GST, and GSH followed suit. Conclusion: From the results it is a clear indication that Allium Cepa Extract can ameliorate the effect of radiation induced disease. 展开更多
关键词 allium Cepa Winstar RAT MDA SOD Hepatoxicity
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Inventory and Management of Fungi Associated with Banana Plant through the Use of Allium ampeloprasum and Cymbopogon citratus Extracts
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作者 Agyingi Lucy Ambang Keuete Kamdoum Elie Maah Romanus Nyamjua 《Journal of Agricultural Chemistry and Environment》 CAS 2023年第2期51-64,共14页
Despite the nutritional, economic and medicinal values of banana plant, independent of the region and production system is confronted with some diseases such as the fungi disease. These fungal diseases are responsible... Despite the nutritional, economic and medicinal values of banana plant, independent of the region and production system is confronted with some diseases such as the fungi disease. These fungal diseases are responsible for the low yields. The objective of this study was to improve the sanitary state of banana plant. To achieve this objective, fungi associated with banana leaves were isolated on Potato Dextrose Agar (PDA) culture medium and their identification was done on the basis of morphological and microscopic characteristics using reference documents. Antifungal activity of Allium ampeloprasum and Cymbopogon citratus extracts were evaluated in vitro on agar medium on the development of Pseudocercospora fijiensis, P. musicola and Pestalopsis sp. The results showed that banana plant harbours a diversity of fungal species, the most frequent being P. fijiensis (51.58%), Pestalopsis sp. (15.47%) and P. musicola (12.03%). Aqueous extracts of C. citratus at the concentration of 15 mg/ml, inhibited 100% of the radial growth of P. fijiensis and Pestalopsis sp with a fungitoxic activity. Similarly, ethanolic extract A. ampeloprasum inhibited at 100% the radial growth of Pestalopsis sp. This antifungal activity was fungistatic. These results suggest that the aqueous and ethanol extracts of the tested plants could be used as alternatives to chemical products in the fight against banana diseases especially Sigatoka. Hence further studies need to be undertaken to isolate the active compounds from these extracts with fungicidal potential. 展开更多
关键词 BANANA FUNGI Cymbopogon citratus allium ampeloprasum Plant Extracts
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Allium覆膜金属输尿管支架置入治疗输尿管狭窄的疗效评价 被引量:15
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作者 王起 刘苗雨 +5 位作者 董文敏 张维宇 王焕瑞 许克新 徐涛 胡浩 《现代泌尿外科杂志》 CAS 2020年第7期601-603,621,共4页
目的初步评价置入Allium覆膜金属输尿管支架治疗输尿管狭窄的疗效及并发症。方法回顾性分析2018年8月至2019年4月收治的39例诊断输尿管狭窄的患者资料,男22例,女17例;年龄18~67岁,平均(46±10)岁。术前B超及CTU检查均提示患侧肾脏积... 目的初步评价置入Allium覆膜金属输尿管支架治疗输尿管狭窄的疗效及并发症。方法回顾性分析2018年8月至2019年4月收治的39例诊断输尿管狭窄的患者资料,男22例,女17例;年龄18~67岁,平均(46±10)岁。术前B超及CTU检查均提示患侧肾脏积水,7例患者为双侧狭窄,共46侧输尿管狭窄。采用输尿管镜经尿道逆行置入Allium支架,均通过X线造影的方式确定狭窄部位并且在透视下留置支架。术后1个月及3个月复查B超、血肌酐,如出现反复发热或置入侧腰痛等梗阻症状则提前复查。随访观察疗效及并发症发生情况。结果本组46侧输尿管狭窄中,36侧输尿管狭窄置入1根Allium支架,3侧输尿管狭窄串联式置入2根Allium支架,7侧输尿管狭窄串联式置入3根Allium支架。术后随访3~9个月。4例患者术后1个月复查时仍提示患侧输尿管狭窄再次行Allium支架管置入,1例患者发生支架管移位后予以拔除支架,其余患者复查B超及血肌酐较术前均明显缓解,复查支架管位置正常。结论Allium覆膜金属输尿管支架用于治疗输尿管狭窄安全有效。对于长段输尿管狭窄,尤其是放疗后输尿管狭窄患者,需要多根串联置入,以达到理想的治疗效果。 展开更多
关键词 allium输尿管支架 输尿管狭窄 allium支架
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ALLIUM■覆膜输尿管支架治疗输尿管狭窄7例报告 被引量:10
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作者 高宇 王保军 +5 位作者 徐衍盛 杜青山 李世超 彭程 张旭 马鑫 《微创泌尿外科杂志》 2020年第5期289-293,共5页
目的:评估ALLIUM?覆膜输尿管支架(URS)治疗输尿管狭窄的安全性和有效性。方法:2019年9-12月收治7例输尿管狭窄患者行ALLIUM?覆膜URS置入术。其中3例为宫颈癌术后放疗致单侧或双侧输尿管狭窄,2例为孤立肾先天性肾盂输尿管连接处梗阻(UPJO... 目的:评估ALLIUM?覆膜输尿管支架(URS)治疗输尿管狭窄的安全性和有效性。方法:2019年9-12月收治7例输尿管狭窄患者行ALLIUM?覆膜URS置入术。其中3例为宫颈癌术后放疗致单侧或双侧输尿管狭窄,2例为孤立肾先天性肾盂输尿管连接处梗阻(UPJO)术后狭窄复发,1例为输尿管镜激光碎石术后单侧输尿管狭窄,1例为孤立肾合并盆腔脂肪增多症致输尿管壁内段狭窄。均采用URS(10~100 mm或10~120mm规格),全部支架经尿道逆行置入,先行球囊扩张,再置入URS。其中2例为双侧支架置入,1例单侧输尿管置入叠放2根URS。共置入10根,中位随访时间4个月(4~7个月)。结果:6例术后肾积水即刻明显缓解,无尿外渗,无腰部胀痛,无血尿和泌尿系感染,1例出现轻度盆腔积液,所有患者通过腹部X线平片和CT证实对狭窄病变的完全支撑。中位术后住院时间3d。随访中2例观察到支架移位,其中1例术后2个月支架脱落至膀胱内,后通过膀胱镜安全移除。另1例支架随肾结石下移后出现输尿管不完全梗阻,予以输尿管镜激光碎石处理。其余支架在随访中位置良好,患者未出现腰痛、血尿、尿路刺激症等不适。结论:短期结果显示ALLIUM?覆膜URS治疗输尿管狭窄安全有效,但仍需更多的病例和更长时间的随访证实疗效。 展开更多
关键词 allium■覆膜输尿管支架 球囊扩张 输尿管狭窄
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内镜下Allium尿管支架置入治疗输尿管狭窄长期留置安全性及有效性分析 被引量:2
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作者 董文敏 胡浩 +2 位作者 乔弘宇 崔刚 冯炳富 《临床和实验医学杂志》 2021年第12期1297-1300,共4页
目的探讨内镜下Allium尿管支架置入治疗输尿管狭窄长期留置安全性及有效性。方法回顾性选择于2018年8月至2020年8月北京市大兴区人民医院与北京大学人民医院收治的输尿管狭窄患者35例,均行内镜下Allium尿管支架置入治疗。记录患者手术... 目的探讨内镜下Allium尿管支架置入治疗输尿管狭窄长期留置安全性及有效性。方法回顾性选择于2018年8月至2020年8月北京市大兴区人民医院与北京大学人民医院收治的输尿管狭窄患者35例,均行内镜下Allium尿管支架置入治疗。记录患者手术时间和术后并发症情况;比较术前和术后6个月肾功能指标变化,血红蛋白水平和肾积水宽度及生活质量变化。结果所有患者均顺利完成手术,其中17例患者输尿管狭窄位于输尿管下段,11例患者位于输尿管中段,7例患者位于输尿管上段。术后随访6个月,置入成功率为100%,手术时间为(94.52±19.83)min,术后均未出现相关并发症。术后6个月血肌酐和尿素氮为(115.42±18.39)μmol/L、(8.98±1.54)mmol/L,均低于术前[(138.35±23.54)μmol/L和(12.12±1.87)mmol/L],差异均有统计学意义(P<0.05)。术后6个月,血红蛋白[(123.18±14.35)g/L]较术前[(125.23±18.93)g/L]差异无统计学意义(P>0.05);术后6个月肾积水宽度为(1.65±0.39)cm,低于术前[(2.74±0.46)cm],差异有统计学意义(P<0.05)。术后6个月,情感功能、社会功能、心理功能和生理功能为(67.94±8.42)、(65.24±7.23)、(70.12±8.49)、(68.42±6.63)分,高于术前[(43.24±7.58)、(47.38±6.52)、(41.32±5.94)和(38.94±5.87)分],差异均有统计学意义(P<0.05)。结论内镜下Allium尿管支架置入治疗输尿管狭窄长期留置安全性良好,且具有良好有效性。 展开更多
关键词 内镜 allium尿管支架 输尿管狭窄 长期留置 安全性 有效性
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输尿管镜下逆行放置Allium覆膜尿路支架系统治疗输尿管单处顽固性狭窄的临床观察 被引量:1
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作者 鹿超 岳闯 +3 位作者 伍豪 苏泉心 储传敏 左立 《上海医药》 CAS 2022年第3期48-51,共4页
目的:观察输尿管镜下逆行放置Allium覆膜尿路支架系统(以下简称Allium支架)治疗输尿管单处顽固性狭窄的安全性和有效性。方法:回顾性分析17例接受Allium支架治疗的输尿管单处顽固性狭窄患者的临床资料。记录患者术后并发症和手术前、后... 目的:观察输尿管镜下逆行放置Allium覆膜尿路支架系统(以下简称Allium支架)治疗输尿管单处顽固性狭窄的安全性和有效性。方法:回顾性分析17例接受Allium支架治疗的输尿管单处顽固性狭窄患者的临床资料。记录患者术后并发症和手术前、后肾积水情况等。结果:对所有患者均一期手术成功。并发症发生率为23.5%。患者术前、术后肾积水情况中位数分别为27和20 mm,术后情况较术前显著改善(P<0.001)。结论:Allium支架对输尿管狭窄段的扩张、支撑效果较好,为慢性、复杂性输尿管狭窄患者提供了一种有价值的治疗选择。由于该支架放置时间尚短,远期效果还待进一步的随访观察。 展开更多
关键词 allium覆膜尿路支架系统 难治性输尿管狭窄 输尿管支架
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浑善达克沙地4种葱属(Allium L.)植物的花粉形态研究
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作者 宛涛 蔡萍 +3 位作者 伊卫东 张晓明 史雪松 张辰波 《内蒙古农业大学学报(自然科学版)》 CAS 2006年第2期21-24,共4页
本文通过采用扫描电镜(SEM),对浑善达克沙地葱属(AlliumL.)4种植物的花粉形态进行了详细的观察描述。掌握了它们在扫描电镜水平上的形状、大小、表面纹饰、萌发器官类型及数量等形态特征。为生态建设、环境保护、地质地貌、植物分类及... 本文通过采用扫描电镜(SEM),对浑善达克沙地葱属(AlliumL.)4种植物的花粉形态进行了详细的观察描述。掌握了它们在扫描电镜水平上的形状、大小、表面纹饰、萌发器官类型及数量等形态特征。为生态建设、环境保护、地质地貌、植物分类及遗传育种等相关研究提供了可靠的孢粉学参考。 展开更多
关键词 花粉形态 (allium L.) 浑善达克沙地
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Allium覆膜金属输尿管支架治疗输尿管狭窄的疗效分析 被引量:7
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作者 石兵 赵凡 +2 位作者 朱建 解吕中 王伟 《中国微创外科杂志》 CSCD 北大核心 2022年第5期407-411,共5页
目的探讨Allium覆膜金属输尿管支架治疗输尿管狭窄的有效性和安全性。方法回顾性分析2020年6月~2021年6月输尿管狭窄19例资料,共置入Allium覆膜金属输尿管支架20根,随访3个月,记录不良反应事件。对19例术前和术后3个月肾盂宽度及尿常规... 目的探讨Allium覆膜金属输尿管支架治疗输尿管狭窄的有效性和安全性。方法回顾性分析2020年6月~2021年6月输尿管狭窄19例资料,共置入Allium覆膜金属输尿管支架20根,随访3个月,记录不良反应事件。对19例术前和术后3个月肾盂宽度及尿常规白细胞、红细胞计数,17例留置双J管者术前和术后3个月输尿管支架相关症状问卷(Ureteral Stent Symptom Questionnaire,USSQ)进行比较。结果19例(20侧)手术顺利,均置入成功。随访3个月,1例(5%,1/20)术后3个月支架上移。术后3个月泌尿系B超肾盂宽度[(1.5±0.2)cm]较术前[(2.1±0.5)cm]明显缩小(t=6.562,P=0.000),尿白细胞计数和红细胞计数均较术前明显减少(P<0.01)。17例术前留置双J管者USSQ问卷总分[(34.2±3.6)分]较术前[(61.2±6.9)分]明显降低(t=19.356,P=0.000),包括下尿路症状、躯体疼痛症状、一般健康状态、工作能力评分均明显降低(P<0.01)。结论Allium覆膜金属输尿管支架置入治疗输尿管狭窄安全有效,可以明显改善肾盂积水和生活质量,其远期疗效仍需要大样本量长时间随访。 展开更多
关键词 输尿管狭窄 覆膜金属输尿管支架 allium支架 有效性 安全性
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