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On the global L^(1)-boundedness of Fourier integral operators with rough amplitude and phase functions
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作者 Joachim Sindayigaya WU Xiao-mei HUANG Qiang 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第4期604-613,共10页
Let T_(ϕ,a)be a Fourier integral operator with amplitude a and phase functions ϕ.In this paper,we study the boundedness of Fourier integral operator of rough amplitude a∈L^(∞)S_(ρ)^(m)and rough phase functionsϕ∈L^... Let T_(ϕ,a)be a Fourier integral operator with amplitude a and phase functions ϕ.In this paper,we study the boundedness of Fourier integral operator of rough amplitude a∈L^(∞)S_(ρ)^(m)and rough phase functionsϕ∈L^(m)ϕ^(2)with some measure condition.We prove the global L^(1)boundedness for T_(ϕ,a),when 1/<ρ≤1 and m<ρ-n+1/2.Our theorem improves some known results. 展开更多
关键词 Fourier integral operators L1-Boundedness rough amplitude rough phase functions
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Calculation of compact amplitude-integrated EEG tracing and upper and lower margins using raw EEG data 被引量:1
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作者 Dandan Zhang Haiyan Ding 《Health》 2013年第5期885-891,共7页
Amplitude-integrated EEG (aEEG) is a popular method for monitoring cerebral function. Although various commercial aEEG recorders have been produced, a detailed aEEG algorithm currently is not available. The upper and ... Amplitude-integrated EEG (aEEG) is a popular method for monitoring cerebral function. Although various commercial aEEG recorders have been produced, a detailed aEEG algorithm currently is not available. The upper and lower margins in the aEEG tracing are the discriminating features for data inspection and tracing classification. However, most aEEG devices require that these margins be measured semi-subjectively. This paper proposes a step-by-step signal-processing method to calculate a compact aEEG tracing and the upper/lower margin using raw EEG data. The high accuracy of the algorithm was verified by comparison with a recognized commercial aEEG device based on a representative testing dataset composed of 72 aEEG data. The introduced digital algorithm achieved compact aEEG tracing with a small data size. Moreover, the algorithm precisely represented the upper and lower margins in the tracing for objective data interpretation. The described method should facilitate aEEG signal processing and further establish the clinical and experimental application of aEEG methods. 展开更多
关键词 amplitude-integrated EEG Digital Algorithm UPPER MARGIN LOWER MARGIN COMPACT TRACING
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Application of Amplitude Ratio Profiles Extracted with Prestack Kirchhoff Integral Migration 被引量:1
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作者 Wu Zhiqin Wang Shangxu +2 位作者 Zhang Shaohong Wang Yun Wang Pengcheng 《Petroleum Science》 SCIE CAS CSCD 2007年第1期36-40,共5页
The Z component and X component profiles of seismic waves extracted with the prestack Kirchhoff integral migration could approximate to the primary wave (P wave) and converted shear wave (PS wave) profiles under c... The Z component and X component profiles of seismic waves extracted with the prestack Kirchhoff integral migration could approximate to the primary wave (P wave) and converted shear wave (PS wave) profiles under certain conditions. The relative change of their reflection amplitude reflects the formation stress anomaly and subsurface media anisotropy. The principle and method for extracting amplitude ratios were studied and the application of amplitude ratio profiles was also examined when processing and interpreting actual seismic data. The amplitude ratio profile is an effective supplementary means of identifying the stratigraphic boundary and lithology. 展开更多
关键词 Prestack Kirchhoff integral migration amplitude ratio profile converted shear wave primary wave LITHOLOGY
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Integral Reduction Arising in Double Transfer and Excitation Amplitude
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作者 A.Zerarla A.Soukeur N.Bensalah 《Communications in Theoretical Physics》 SCIE CAS CSCD 2010年第3期551-554,共4页
The purpose of this article is to develop an integral derived from the double transfer and excitation theory. The reduced form of this integral, so obtained, can serve in the computation of the transition amplitude wh... The purpose of this article is to develop an integral derived from the double transfer and excitation theory. The reduced form of this integral, so obtained, can serve in the computation of the transition amplitude which is from numerical point of view difficult to implement. This amplitude is of great interest in the resonant and non resonant transfer and excitation (RTE and NTE) processes. 展开更多
关键词 amplitude RESONANT TRANSFER EXCITATION integrAL
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The Rise of Solitons in Sine-Gordon Field Theory: From Jacobi Amplitude to Gudermannian Function
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作者 Leonardo Mondaini 《Journal of Applied Mathematics and Physics》 2014年第13期1202-1206,共5页
We show how the famous soliton solution of the classical sine-Gordon field theory in (1 + 1)-dimensions may be obtained as a particular case of a solution expressed in terms of the Jacobi amplitude, which is the inver... We show how the famous soliton solution of the classical sine-Gordon field theory in (1 + 1)-dimensions may be obtained as a particular case of a solution expressed in terms of the Jacobi amplitude, which is the inverse function of the incomplete elliptic integral of the first kind. 展开更多
关键词 SOLITONS SINE-GORDON Field Theory Elliptic integrALS JACOBI amplitude
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Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury 被引量:15
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作者 Wendong You Qilin Tang +4 位作者 Xiang Wu Junfeng Feng Qing Mao Guoyi Gao Jiyao Jiang 《Neuroscience Bulletin》 SCIE CAS CSCD 2018年第4期639-646,共8页
Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in ... Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in coma patients. From January 2013 to January 2016, 128 coma patients after acute brain injury were prospectively enrolled and monitored with aEEG. The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale. aEEG monitoring commenced at a median of 7.5 days after coma onset. Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6% and specificity of 85.2%. In contrast, continuous extremely low voltage, burst-suppression, or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5% and specificity of 100%. In conclusion, aEEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury. 展开更多
关键词 amplitude-integrated electroencephalography -Coma Acute brain injury OUTCOME
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A Systematization for One-Loop 4D Feynman Integrals-Different Species of Massive Fields
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作者 O. A. Battistel G. Dallabona 《Journal of Modern Physics》 2012年第10期1408-1449,共42页
A systematization for the manipulations and calculations involving divergent (or not) Feynman integrals, typical of the one loop perturbative solutions of Quantum Field Theory, is proposed. A previous work on the same... A systematization for the manipulations and calculations involving divergent (or not) Feynman integrals, typical of the one loop perturbative solutions of Quantum Field Theory, is proposed. A previous work on the same issue is generalized to treat theories and models having different species of massive fields. An improvement on the strategy is adopted so that no regularization needs to be used. The final results produced, however, can be converted into the ones of reasonable regularizations, especially those belonging to the dimensional regularization (in situations where the method applies). Through an adequate interpretation of the Feynman rules and a convenient representation for involved propagators, the finite and divergent parts are separated before the introduction of the integration in the loop momentum. Only the finite integrals obtained are in fact integrated. The divergent content of the amplitudes are written as a combination of standard mathematical object which are never really integrated. Only very general scale properties of such objects are used. The finite parts, on the other hand, are written in terms of basic functions conveniently introduced. The scale properties of such functions relate them to a well defined way to the basic divergent objects providing simple and transparent connection between both parts in the assintotic regime. All the arbitrariness involved in this type of calculations are preserved in the intermediary steps allowing the identification of universal properties for the divergent integrals, which are required for the maintenance of fundamental symmetries like translational invariance and scale independence in the perturbative amplitudes. Once these consistency relations are imposed no other symmetry is violated in perturbative calculations neither ambiguous terms survive at any theory or model formulated at any space-time dimension including nonrenormalizable cases. Representative examples of perturbative amplitudes involving different species of massive fermions are considered as examples. The referred amplitudes are calculated in detail within the context of the presented strategy (and systematization) and their relations among other Green functions are explicitly verified. At the end a generalization for the finite functions is presented. 展开更多
关键词 FEYNMAN integrALS Perturbative amplitudeS
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Fuzzification of Feynman Path Integral and Its Effect on Field Theory and Quantum Gravity—Reformation and Redevelopment of Quantum Theory
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作者 Wenbing Qiu 《Journal of Modern Physics》 2020年第12期2053-2065,共13页
The quantum probability theory of fuzzy event is suggested by using the idea and method of fuzzy mathematics, giving the form of fuzzy event path integral, membership degree amplitude, fuzzy field function, Green func... The quantum probability theory of fuzzy event is suggested by using the idea and method of fuzzy mathematics, giving the form of fuzzy event path integral, membership degree amplitude, fuzzy field function, Green function, physical quantity and fuzzy diagram. This theory reforms quantum mechanics, making the later become its special case. This theory breaks unitarity, gauge invariance, probability conservation and information conservation, making these principles become approximate ones under certain conditions. This new theory, which needs no renormalization and can naturally give meaningful results which are in accordance with the experiments, is the proper theory to describe microscopic high-speed phenomenon, whereas quantum mechanics is only a proper theory to describe microscopic low-speed phenomenon. This theory is not divergent under the condition of there being no renormalization and infinitely many offsetting terms, thereby it can become the theoretical framework required for the quantization of gravity. 展开更多
关键词 Quantum Probability Fuzzy Event Path integral Membership Degree Membership Degree amplitude Fuzzy Graph
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Clinical Manifestations and Amplitude-integrated Encephalogram in Neonates with Early-onset Epileptic Encephalopathy
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作者 Li-Li Liu Xin-Lin Hou +6 位作者 Dan-Dan Zhang Guo-Yu Sun Cong-Le Zhou Yi Jiang Ze-Zhong Tang Rui Zhang Yun Cui 《Chinese Medical Journal》 SCIE CAS CSCD 2017年第23期2808-2815,共8页
Background: The patients with early-onset epileptic encephalopathy (EOEE) suffer from neurodevelopmental delay. The aim of this study was to analyze the clinical manifestations and amplitude-integrated encephalogr... Background: The patients with early-onset epileptic encephalopathy (EOEE) suffer from neurodevelopmental delay. The aim of this study was to analyze the clinical manifestations and amplitude-integrated encephalogram (aEEG) characteristics of infants with EOEE with onset within the neonatal period, to make early diagnosis to improve the prognosis. Methods: One-hundred and twenty-eight patients with neonatal seizure were enrolled and followed up till 1 year old. Sixty-six neonates evolved into EOEE were as the EOEE group, the other 62 were as the non-EOEE (nEOEE) group. Then we compared the clinical and aEEG characteristics between the two groups to analyze the manifestations in neonates with EOEE. Results: Compared to the nEOEE group, the incidence of daily seizure attacks, more than two types of convulsions, more than two antiepileptic drugs (AEDs) application, severely abnormal aEEG background, absence of cyclicity, and more than two seizures detection were significantly higher in the EOEE group (P 〈 0.05) (97% vs. 54.8%; 30.3% vs. 14.5%; 97.0% vs. 25.4%; 39.4% vs. 3.2%; 57.6% vs. 9.7%; and 56% vs. 3.2%, respectively). Severely abnormal background pattern (odds ratio [OR] = 0.081, 95% confidence interval [CI]:0.009-0.729, P = 0.025) and more than two seizures detection by aEEG (OR = 0.158, 95% CI: 0.043-0.576, P = 0.005) were the independent risk factors for the evolvement into EOEE. The upper and lower margins of active sleep (AS) and quiet sleep (QS) were significantly higher in EOEE group than those of the control group (P 〈 0.05) (34.3 ± 13.6 vs. 21.3 ± 6.4; 9.9 ± 3.7 vs. 6.7 ± 2.2; 41.2 ± 15.1 vs. 30.4 ± 11.4;and 11.9 ± 4.4 vs. 9.4 ± 4.0; unit: μV, respectively). AS upper margin was demonstrated a higher diagnostic specificity and sensitivity for EOEE than another three parameters according to the receiver operating characteristic curves; the area under the curve was 0.827. Conclusions: The clinical characteristics of the neonatal seizure which will evolve into EOEE were more than two AEDs application, high seizure frequency (daily attack), and more than two types of the seizure. Significant high voltage, severely abnormal background, absence of cyclicity, and more than two seizures detected on aEEG were the meaningful indicators to the prediction of EOEE. 展开更多
关键词 amplitude-integrated Electroencepholography: Early-onset Epileptic Encephalopathy: Neonatal-onset: Newborn
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基于一种新型正弦幅值积分器的谐波检测方法 被引量:1
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作者 苗长新 祝宇航 +1 位作者 赵文鹏 刘家明 《电力系统保护与控制》 EI CSCD 北大核心 2024年第2期39-47,共9页
针对基于瞬时无功理论的ip-iq谐波检测法结构复杂、响应速度慢等问题,提出了一种采用改进正弦幅值积分器结构的谐波电流检测方法。首先,利用二阶广义积分器的输出滤波特性及正弦幅值积分器的极性选择特性,使其相结合构造出了一种滤波性... 针对基于瞬时无功理论的ip-iq谐波检测法结构复杂、响应速度慢等问题,提出了一种采用改进正弦幅值积分器结构的谐波电流检测方法。首先,利用二阶广义积分器的输出滤波特性及正弦幅值积分器的极性选择特性,使其相结合构造出了一种滤波性能更强,同时具有频率及极性选择作用的新型积分器。然后,利用该积分器快速准确地提取基波正序分量,并有效应用于谐波检测环节中。当电网电压存在直流偏置问题时,该积分器所构造的锁相环也能准确锁定电网频率及相位信息。最后,理论分析及仿真实验结果表明:该方法无需进行瞬时对称分量分离,就可提取出电网电压及负载电流基波的正负序分量,计算量小,谐波检测更精确。 展开更多
关键词 谐波检测 正弦幅值积分器 基波正序分量 直流偏置 锁相环
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振幅整合脑电图评估孕妇产前糖皮质激素治疗对早产儿脑发育的影响
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作者 吴迪 鞠俊 常贺生 《中国当代儿科杂志》 CAS CSCD 北大核心 2024年第3期244-249,共6页
目的通过振幅整合脑电图(amplitude-integrated electroencephalography,aEEG)探讨孕妇产前糖皮质激素(antenatal corticosteroid,ACS)治疗对早产儿脑发育的影响。方法回顾性纳入胎龄28^(+0)~34^(+6)周早产儿211例,根据产前是否使用地... 目的通过振幅整合脑电图(amplitude-integrated electroencephalography,aEEG)探讨孕妇产前糖皮质激素(antenatal corticosteroid,ACS)治疗对早产儿脑发育的影响。方法回顾性纳入胎龄28^(+0)~34^(+6)周早产儿211例,根据产前是否使用地塞米松进行促胎肺成熟治疗分为ACS组(131例)和对照组(80例)。在生后24 h内进行首次aEEG监测(记为aEEG1),生后5~7 d进行第2次aEEG监测(记为aEEG2),对aEEG结果进行分析比较。结果胎龄28^(+0)~31^(+6)周早产儿中,ACS组相较于对照组,aEEG1周期性更成熟、振幅下边界更高(P<0.05);胎龄32^(+0)~33^(+6)周及胎龄34^(+0)~34^(+6)周早产儿中,ACS组相较于对照组,连续模式比例更高、周期性更成熟且Burdjalov评分更高(P<0.05)。胎龄32^(+0)~33^(+6)周及胎龄34^(+0)~34^(+6)周早产儿中,ACS组相较于对照组,aEEG2连续模式比例更高、周期性更成熟、振幅下边界更高、波谱带宽更窄且Burdjalov评分更高(P<0.05)。结论ACS治疗早产儿比未行ACS早产儿aEEG图形更成熟,ACS对早产儿脑发育有一定促进作用。 展开更多
关键词 脑发育 产前糖皮质激素 振幅整合脑电图 早产儿
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振幅整合脑电图对感染新生儿化脓性脑膜炎早期诊断的作用以及预后的预测价值
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作者 赵庭鉴 《中南医学科学杂志》 CAS 2024年第5期748-751,共4页
目的 探讨振幅整合脑电图对感染新生儿化脓性脑膜炎早期诊断的作用以及预后的预测价值。方法 收集确诊为感染的新生儿52例,确诊后24 h内根据振幅整合脑电图(aEEG)检测结果分为正常组、轻度异常组、重度异常组。比较各组出生6个月时贝利... 目的 探讨振幅整合脑电图对感染新生儿化脓性脑膜炎早期诊断的作用以及预后的预测价值。方法 收集确诊为感染的新生儿52例,确诊后24 h内根据振幅整合脑电图(aEEG)检测结果分为正常组、轻度异常组、重度异常组。比较各组出生6个月时贝利婴儿发育量表评估及出生12个月时Gesell发育量表评分。以脑脊液生化检查作为评估金标准,判断感染的新生儿52例中化脓性脑膜炎例数。ROC分析aEEG对新生儿化脓性脑膜炎的诊断效能。结果 患儿在出生6个月时进行贝利婴儿发育量表评估31例正常,11例过渡,10例异常,贝利婴儿发育量表评估结果在不同程度aEEG组间差异存在统计学意义(P<0.05)。aEEG异常患儿的Gesell发育量表3项检测值均较aEEG正常患儿低(P<0.05)。感染新生儿52例中有10例患儿存在化脓性脑膜炎。ROC分析显示,aEEG诊断新生儿化脓性脑膜炎具有良好的诊断效能。结论 aEEG对感染性新生儿化脓性脑膜炎的早期诊断及预后的预测具有重要的意义。 展开更多
关键词 振幅整合脑电图 新生儿 感染 化脓性脑膜炎
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振幅整合脑电图参数联合血气指标分析评估缺氧缺血性脑病的预测价值
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作者 赵庭鉴 王丽 刘曼 《中外医疗》 2024年第15期36-39,共4页
目的 评估振幅整合脑电图参数联合血气指标分析对缺氧缺血性脑病的预测价值。方法 回顾性选取2018年4月—2022年12月桂林医学院附属医院收治的35例缺氧缺血性脑病患儿的临床资料为观察组,同时选择57例正常儿童资料为对照组,采用ROC曲线... 目的 评估振幅整合脑电图参数联合血气指标分析对缺氧缺血性脑病的预测价值。方法 回顾性选取2018年4月—2022年12月桂林医学院附属医院收治的35例缺氧缺血性脑病患儿的临床资料为观察组,同时选择57例正常儿童资料为对照组,采用ROC曲线评估振幅整合脑电图联合血气分析对缺氧缺血性脑病的预测价值。结果 观察组波谱带上边界、波谱带下边界、氧分压低于对照组,二氧化碳分压高于对照组,差异有统计学意义(P均<0.05);两组患儿pH值、碳酸氢盐水平比较,差异无统计学意义(P均>0.05)。联合检测在ROC曲线中的AUC最大为0.969,其诊断效能最高。结论 振幅整合脑电图参数联合血气分析指标能有效预测缺氧缺血性脑病患儿病情,有利于临床及时开展相应治疗。 展开更多
关键词 振幅整合脑电图 血气分析 缺氧缺血性脑病
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脑氧饱和度监测结合振幅整合脑电图对早产儿脑损伤神经行为发育的预测价值
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作者 刘晓静 司志梅 +2 位作者 马欢欢 许晶晶 田鑫 《临床误诊误治》 CAS 2024年第21期55-61,共7页
目的探讨脑氧饱和度(rSO_(2))监测结合振幅整合脑电图(aEEG)对早产儿脑损伤(BIPI)预测神经行为发育的临床意义,以利于早期采取相应措施,改善患儿预后。方法选取2022年2月至2023年2月收治的116例BIPI作为观察组,选择非BIPI作为对照组,均... 目的探讨脑氧饱和度(rSO_(2))监测结合振幅整合脑电图(aEEG)对早产儿脑损伤(BIPI)预测神经行为发育的临床意义,以利于早期采取相应措施,改善患儿预后。方法选取2022年2月至2023年2月收治的116例BIPI作为观察组,选择非BIPI作为对照组,均行aEEG、rSO_(2)检查。比较2组aEEG评分、rSO_(2),对比观察组不同胎龄、脑损伤程度、神经行为发育情况患儿aEEG评分、rSO_(2),分析aEEG总分、rSO_(2)与胎龄、神经行为发育、脑损伤程度的相关性,分析aEEG总分、rSO_(2)对BIPI神经行为发育异常的预测价值。结果观察组连续性、睡眠-觉醒周期、下边界振幅、带宽和下边界值及aEEG总分、rSO_(2)低于对照组(P<0.01);观察组不同胎龄、脑损伤程度、神经行为发育患儿连续性、睡眠-觉醒周期、下边界振幅、带宽和下边界值及aEEG总分、rSO_(2)比较差异有统计学意义(P<0.05,P<0.01);Spearman相关性分析显示,aEEG总分、rSO_(2)与胎龄呈正相关(r=0.654、0.678,P<0.01),与脑损伤程度、神经行为发育呈负相关(r=-0.642、-0.747,P<0.01;r=-0.687、-0.659,P<0.01)。aEEG评分、rSO_(2)单独及联合预测BIPI神经行为发育异常的曲线下面积分别为0.813、0.810、0.909,联合预测的曲线下面积大于单独预测。结论aEEG评分、rSO_(2)过低与BIPI胎龄、神经行为发育及脑损伤程度存在一定关联,联合检测aEEG评分、rSO_(2)可预测BIPI神经行为发育异常风险,指导临床早期采取干预措施,防止或减少后遗症发生。 展开更多
关键词 脑氧饱和度 振幅整合脑电图 婴儿 早产 脑损伤 神经行为发育 胎龄 受试者工作特征
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基于傅里叶变换的振动切削刀具振幅测量方法
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作者 于保军 胡锋 +1 位作者 郝兆鹏 贾志远 《机械设计与制造》 北大核心 2024年第1期314-317,326,共5页
振动切削在当今时代的制造业越来越普遍,而振动切削的关键参数刀具振幅又因能量损失而无法避免,为了能保证良好的切削效果,需要知道实际切削过程中的刀具振幅。目前普遍使用激光测振仪测量振动切削的刀具振幅,但设备较为昂贵。为了实现... 振动切削在当今时代的制造业越来越普遍,而振动切削的关键参数刀具振幅又因能量损失而无法避免,为了能保证良好的切削效果,需要知道实际切削过程中的刀具振幅。目前普遍使用激光测振仪测量振动切削的刀具振幅,但设备较为昂贵。为了实现对振动切削刀具振幅经济有效的测量,提出了一种利用加速度传感器测量振动切削刀具振幅的测量方法。利用加速度传感器获得刀具振动方向的加速度,通过傅里叶变换和频域二次积分以及傅里叶反变换,将加速度信号积分为振幅信号。根据实验结果可知,本测量系统的测量误差低于0.8%。 展开更多
关键词 振动切削 加速度传感器 傅里叶反变换 频域二次积分 振幅测量
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血清Nesfatin-1联合aEEG在早产儿脑损伤诊断及短期神经发育预测中的应用 被引量:1
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作者 向晶晶 王云 王玉 《中国妇幼健康研究》 2024年第3期20-26,共7页
目的 探究血清Nesfatin-1联合振幅整合脑电图(aEEG)在早产儿脑损伤诊断和短期神经发育预测中的应用价值。方法 选取2022年2月至2023年3月期间在河北大学附属医院新生儿重症监护室住院治疗的早产儿89例为研究对象,分为合并脑损伤组(n=50... 目的 探究血清Nesfatin-1联合振幅整合脑电图(aEEG)在早产儿脑损伤诊断和短期神经发育预测中的应用价值。方法 选取2022年2月至2023年3月期间在河北大学附属医院新生儿重症监护室住院治疗的早产儿89例为研究对象,分为合并脑损伤组(n=50)和未合并脑损伤组(n=39);合并脑损伤组按照胎龄分成胎龄<32周组(n=24)、胎龄32~33周组(n=14)和胎龄34~37周组(n=12)。所有入选早产儿均在生后24h内进行血清Nesfatin-1水平检测,72h内进行aEEG检测,住院期间完善头颅核磁(MRI)检查,并在纠正胎龄达40周时行神经行为测定评分(NBNA),纠正胎龄3个月时行Gesell发育量表测定。对血清Nesfatin-1、aEEG评分与NBNA评分、Gesell各能区发育商进行相关性分析。应用受试者工作特征(ROC)曲线评估血清Nesfatin-1联合aEEG在早产儿脑损伤早期诊断中的应用价值。结果 合并脑损伤组患儿的血清Nesfatin-1水平高于未合并脑损伤组,aEEG各指标评分及Gesell各能区发育商均低于未合并脑损伤组,差异有统计学意义(Z值介于-8.039~-3.030之间,P<0.01);3组不同胎龄患儿的血清Nesfati-1水平差异无统计学意义(P>0.05);胎龄<32周组的aEEG连续性、波带宽度和总评分均低于胎龄34~37周组,胎龄32~33周组的aEEG连续性低于胎龄34~37周组,差异均有统计学意义(H值介于10.766~24.600之间,P<0.01);血清Nesfatin-1水平与NBNA评分、Gesell各能区发育商之间显著负相关(r值介于-0.582~-0.438之间,P<0.01);aEEG总评分与NBNA评分、Gesell各能区发育商显著正相关(r值介于0.479~0.572之间,P<0.01);血清Nesfatin-1水平、aEEG评分和二者联合诊断早产儿脑损伤的曲线下面积依次为0.868、0.834、0.903。结论 合并脑损伤组早产儿血清中的Nesfatin-1水平在生后早期有所增加,而aEEG监测指标均下降,二者均与早产儿的神经发育密切相关。 展开更多
关键词 早产儿 脑损伤 血清Nesfatin-1 振幅整合脑电图 神经发育
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高海拔地区健康足月新生儿脑氧代谢及脑电活动差异的多中心临床研究方案
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作者 泽碧 高瑾 +13 位作者 赵晓芬 李杨方 张铁松 刘晓梅 毛辉 秦明彩 张奕 杨永礼 和春叶 赵燕 杜琨 刘玲 周文浩 中国高原新生儿医学联盟 《中国当代儿科杂志》 CAS CSCD 北大核心 2024年第4期403-409,共7页
高原环境对新生儿神经功能的影响仍需进一步证据积累。通过无创脑近红外光谱技术和振幅整合脑电图检测技术可提供脑氧饱和度及脑电活动数据。该研究通过对不同海拔梯度健康足月新生儿生后3 d内不同时间点进行多次近红外光谱技术、振幅... 高原环境对新生儿神经功能的影响仍需进一步证据积累。通过无创脑近红外光谱技术和振幅整合脑电图检测技术可提供脑氧饱和度及脑电活动数据。该研究通过对不同海拔梯度健康足月新生儿生后3 d内不同时间点进行多次近红外光谱技术、振幅整合脑电图监测,将测得的脑氧饱和度、脑电活动数据在不同海拔间进行比较,并建立相应的参考值范围。该研究包括6家中国高原新生儿医学联盟参与单位,根据所在地海拔分为4个海拔梯度,分别是800 m、1900 m、2400 m和3500 m,每个海拔梯度预计样本量170人。该多中心前瞻性队列研究将为高原环境对新生儿早期脑功能及代谢的影响提供证据支持。 展开更多
关键词 近红外光谱 脑组织氧饱和度 振幅整合脑电图 高原 新生儿
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振幅整合脑电图在高原地区住院新生儿中的监测结果分析
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作者 赵晓芬 程国强 +4 位作者 赵朋娜 赵玫 朱双燕 李杨方 周文浩 《中国当代儿科杂志》 CAS CSCD 北大核心 2024年第8期817-822,共6页
目的分析高原地区住院新生儿进行振幅整合脑电图(amplitude-integrated electroencephalography,aEEG)监测的结果。方法回顾性选取2020年1月-2022年12月在昆明市儿童医院新生儿科住院并接受aEEG监测的5945例患儿为研究对象,根据aEEG监... 目的分析高原地区住院新生儿进行振幅整合脑电图(amplitude-integrated electroencephalography,aEEG)监测的结果。方法回顾性选取2020年1月-2022年12月在昆明市儿童医院新生儿科住院并接受aEEG监测的5945例患儿为研究对象,根据aEEG监测结果分为aEEG正常组与aEEG异常组。分析各系统疾病aEEG异常发生率,aEEG异常表现及aEEG异常与临床异常情况的一致性。结果5945例患儿中,aEEG异常率为19.28%(1146/5945),其中危重患儿异常率29.58%(906/3063),非危重患儿异常率为8.33%(240/2882),差异有统计学意义(P<0.05)。aEEG异常率较高的前三位主诊断疾病依次是遗传代谢性疾病60.77%(79/130)、中枢神经系统疾病42.22%(76/180)、早产儿35.53%(108/304)。aEEG异常组日龄及胎龄均小于aEEG正常组,早产儿出生体重低于aEEG正常组(P<0.05)。1146例aEEG异常患儿中,aEEG异常类型主要有睡眠觉醒周期异常597例(52.09%)、背景活动异常294例(25.65%)和痫样活动255例(22.25%);有异常临床表现者902例(78.71%)。aEEG监测脑功能异常的灵敏度为33.51%,特异度为92.50%。结论高原地区住院新生儿尤其是危重儿、胎龄及日龄小的患儿,aEEG异常率较高,提示脑损伤风险也较高,故对住院新生儿常规进行aEEG监测有利于早期发现脑功能异常,有助于决策治疗并做好脑保护策略。 展开更多
关键词 振幅整合脑电图 高原地区 脑功能监测 新生儿
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改良版口腔运动干预对早产儿脑功能发育及喂养表现的影响
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作者 赵晓燕 陈凡 +3 位作者 王自珍 陈华燕 张倩莹 黄婕 《中国医药指南》 2024年第11期48-52,共5页
目的探讨改良版口腔运动干预对早产儿脑功能发育、喂养表现及住院时间的影响。方法筛选厦门大学附属妇女儿童医院及中国人民解放军总医院第七医学中心2021年4月至2023年4月期间符合纳入标准的204例早产儿为研究对象,随机分为对照组(69例... 目的探讨改良版口腔运动干预对早产儿脑功能发育、喂养表现及住院时间的影响。方法筛选厦门大学附属妇女儿童医院及中国人民解放军总医院第七医学中心2021年4月至2023年4月期间符合纳入标准的204例早产儿为研究对象,随机分为对照组(69例)、PIOMIs组(67例)及IPIOMIs组(68例)。对照组实施早产儿常规支持护理及非营养性吸吮;PIOMIs组在对照组基础上加入LESSEN版口腔运动干预;IPIOMIs组在对照组基础上加入改良版口腔运动干预。结果与对照组相比,IPIOMIs组完全经口喂养时睡眠觉醒周期评分、宽带评分、aEEG评分总分、完全经口摄入奶量比及完全经口摄奶熟练度均升高,PIOMIs组睡眠觉醒周期评分和aEEG评分总分明显升高;IPIOMIs组和PIOMIs组全经口喂养过度时间和住院时长缩短,体重增长率升高(均P<0.05)。与PIOMOs组相比,IPIOMIs组住院时间缩短,体重增长率明显升高(均P<0.05)。结论改良版口腔运动干预可有效促进早产儿口腔运动功能,加速脑功能发育和喂养进程,改善喂养表现,缩短住院时间,帮助患儿早日康复。 展开更多
关键词 早产儿 口腔运动干预 振幅整合脑电图 喂养表现
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左乙拉西坦联合奥卡西平治疗癫痫患儿疗效及其对脑损伤指标的影响 被引量:1
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作者 张冬艳 李彤 +4 位作者 张丽娜 王雪勤 王建忠 李学超 张芳 《川北医学院学报》 CAS 2024年第8期1085-1088,共4页
目的:探讨左乙拉西坦(LEV)联合奥卡西平(OXC)治疗癫痫的疗效。方法:根据治疗手段不同将113例癫痫患儿分为联合组(n=56)和单药组(n=57)。联合组行LEV联合OXC治疗;单药组给予OXC治疗。比较两组患儿临床疗效、癫痫发作情况、脑损伤水平[改... 目的:探讨左乙拉西坦(LEV)联合奥卡西平(OXC)治疗癫痫的疗效。方法:根据治疗手段不同将113例癫痫患儿分为联合组(n=56)和单药组(n=57)。联合组行LEV联合OXC治疗;单药组给予OXC治疗。比较两组患儿临床疗效、癫痫发作情况、脑损伤水平[改良振幅整合脑电图(aEEG)、中枢神经特异蛋白S100β(S-100β)、神经胶质纤维酸性蛋白(GFAP)]、认知功能[韦氏儿童智力测试表(WISC-CR)]、炎症因子水平和并发症发生情况。结果:治疗6个月后,联合组患儿临床疗效高于单药组(P<0.05);两组患儿发作次数、持续时间、改良aEEG评分、S-100β、GFAP水平、炎症因子水平均降低(P<0.05),且联合组低于单药组(P<0.05);两组患儿WISC-CR评分均升高(P<0.05),且联合组高于单药组(P<0.05);两组并发症总发生率差异无统计学意义(P>0.05)。结论:LEX联合OXC治疗癫痫患儿可显著改善脑组织损伤,促进认知功能恢复,治疗效果良好且安全性较高。 展开更多
关键词 癫痫 左乙拉西坦 奥卡西平 改良振幅整合脑电图评分 认知功能
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