Objective To observe the intervention effects of acupuncture combined with standardized treatment of western medicine on blood-stasis syndrome in unstable angina(UA)patients with different thrombolysis in myocardial i...Objective To observe the intervention effects of acupuncture combined with standardized treatment of western medicine on blood-stasis syndrome in unstable angina(UA)patients with different thrombolysis in myocardial infarction(TIMI)risk stratification.Methods According to TIMI risk score,a total of 72 UA patients were included,24 cases in low-risk(0 to 2 points)group,24展开更多
Objectives To study change and the clinical significance of fibrinolysis in coronary heart disease(CHD) patients with angina pactoris(AP).Methods Levels of plas-min plasminogen activator inhibitor-1(PAI-1),tissue-type...Objectives To study change and the clinical significance of fibrinolysis in coronary heart disease(CHD) patients with angina pactoris(AP).Methods Levels of plas-min plasminogen activator inhibitor-1(PAI-1),tissue-type plasminogen activator(t-PA),fibrinogen(FIB) in 110 CHD patients with AP and 20 normal cases as control group were analyzed in the same ways.Results Levels of PAI-1,FIB in CHD patients with AP were significantly higher than those in control cases,and those of t-PA were significantly lower than control cases;Levels of PAI-1,FIB in UA patients with UA heart events were significantly higher than those in patients with SA,and those of t-PA were significantly lower than patients with SA;Levels of PAI-1,FIB in patients with AP events were significantly higher than those in patients without AP events,and those of t-PA were significantly lower than patients without AP events.Conclusions There was abnormal of fibrinolysis function in CHD patients with AP, specially in patients with UA or with AP events,the abnormal of fibrinolysis might be play an important rule in coronary heart disease(CHD) patients with angina pactoris.展开更多
Coronary artery vasospasm is an infrequent cause of acute coronary syndrome (ACS). A 50-year-old female developed persistent chest discomfort related to anterior STEMI. After an unsuccessful thrombolysis attempt, due ...Coronary artery vasospasm is an infrequent cause of acute coronary syndrome (ACS). A 50-year-old female developed persistent chest discomfort related to anterior STEMI. After an unsuccessful thrombolysis attempt, due to delay concern, the patient was then sent to the catheterization laboratory for rescue PCI. The coronary angiogram revealed a TIMI 3 flow proximal LAD significant stenosis with spastic appearance of the coronary arteries which has improved after intracoronary nitrates administration. Optical Coherence Tomography (OCT) excluded coronary artery dissection and haematoma also revealed thrombus on moderate atherosclerotic plaque. The patient was then pain-free;she was managed medically and discharged after few days of monitoring. Three weeks later, she developed transient chest pain with ST segment elevation while cycling during rehabilitation program. Provocation test by Ergonovine was positive with complete occlusion of proximal RCA (right coronary artery) complicated by transient complete heart block and shock. She was stabilized with 7 mg of intracoronary nitrates injection. She was discharged after close monitoring with calcium channel blocker and tobacco cessation. ACS may complicate prolonged coronary artery vasospasm making the diagnosis challenging. OCT may help understand ACS mechanism and exclude spontaneous coronary artery dissection. Provocation test is crucial for confirmation.展开更多
目的基于质性研究meta整合收集稳定型心绞痛患者的体验和感受。方法检索中国知网、万方数据知识服务平台、维普网、SinoMed、PubMed、EMbase、The Cochrane Library、澳大利亚乔安娜布里格斯研究所、EBSCO和Web of Science核心合集数据...目的基于质性研究meta整合收集稳定型心绞痛患者的体验和感受。方法检索中国知网、万方数据知识服务平台、维普网、SinoMed、PubMed、EMbase、The Cochrane Library、澳大利亚乔安娜布里格斯研究所、EBSCO和Web of Science核心合集数据库中关于稳定型心绞痛患者体验和感受的质性研究或混合研究,检索时限为建库至2024年3月。2名调查员进行独立文献筛选、数据提取和文献质量评价,使用汇集性整合方法整合结果,并使用CERQual对整合结果信度进行分级。结果共纳入7篇文献,提炼出20个主题,最终归纳为8个类别并形成3个整合结果,分别是多维度影响患者生活质量、患者对当前接受治疗的看法及患者存在未满足的临床需求。结论稳定型心绞痛广泛影响患者的生活、心理和社会功能,应探索以患者为中心的医疗管理模式,充分了解患者感受和需求,并将其纳入未来的医疗决策。由于研究的局限性,未来应在国内开展高质量的质性研究,收集中国稳定型心绞痛患者的体验和感受。展开更多
目的:探讨注射用丹参多酚酸盐治疗高龄冠心病心绞痛病人的临床疗效观察及其对血脂、B型钠尿肽(Brain natriuretic,BNP)、C型反应性蛋白(C-reactive protein,CRP)的影响。方法:选取2016-01~2016-08期间于内蒙古自治区人民医院干部保健所...目的:探讨注射用丹参多酚酸盐治疗高龄冠心病心绞痛病人的临床疗效观察及其对血脂、B型钠尿肽(Brain natriuretic,BNP)、C型反应性蛋白(C-reactive protein,CRP)的影响。方法:选取2016-01~2016-08期间于内蒙古自治区人民医院干部保健所住院的高龄冠心病心绞痛病人64例,按随机原则分为治疗组(37例)和对照组(25例)。对照组给予常规抗心肌缺血治疗,治疗组给予注射用丹参多酚酸盐联合常规药物治疗。观察2wk后两组病人的心绞痛症状、心电图、血脂、BNP、CRP的改善情况。结果:两组病人的心绞痛症状、心电图、血脂、BNP、CRP均比治疗前改善明显,差异均有统计学意义(P<0.05);治疗后高密度脂蛋白(high density lipoproteins,HDL)、左室射血分数(left vertricular ejection fraction,LVEF)水平均较治疗前有明显升高,差异均有统计学意义(P<0.05);治疗组治疗后甘油三酯(Triglyceride,TG)、后清总胆固醇(serum total cholesterd,TC)、低密度脂蛋白(low density lipoprotein,LDL)、C型反应性蛋白(C-reactive protein,CRP)、BNP水平较对照组下降更明显(P<0.05),治疗组治疗后HDL、LVEF水平较对照组升高更明显(P<0.05)。结论:注射用丹参多酚酸盐能显著提高高龄冠心病心绞痛病人的临床疗效及改善BNP、CRP、血脂水平。展开更多
文摘Objective To observe the intervention effects of acupuncture combined with standardized treatment of western medicine on blood-stasis syndrome in unstable angina(UA)patients with different thrombolysis in myocardial infarction(TIMI)risk stratification.Methods According to TIMI risk score,a total of 72 UA patients were included,24 cases in low-risk(0 to 2 points)group,24
文摘Objectives To study change and the clinical significance of fibrinolysis in coronary heart disease(CHD) patients with angina pactoris(AP).Methods Levels of plas-min plasminogen activator inhibitor-1(PAI-1),tissue-type plasminogen activator(t-PA),fibrinogen(FIB) in 110 CHD patients with AP and 20 normal cases as control group were analyzed in the same ways.Results Levels of PAI-1,FIB in CHD patients with AP were significantly higher than those in control cases,and those of t-PA were significantly lower than control cases;Levels of PAI-1,FIB in UA patients with UA heart events were significantly higher than those in patients with SA,and those of t-PA were significantly lower than patients with SA;Levels of PAI-1,FIB in patients with AP events were significantly higher than those in patients without AP events,and those of t-PA were significantly lower than patients without AP events.Conclusions There was abnormal of fibrinolysis function in CHD patients with AP, specially in patients with UA or with AP events,the abnormal of fibrinolysis might be play an important rule in coronary heart disease(CHD) patients with angina pactoris.
文摘Coronary artery vasospasm is an infrequent cause of acute coronary syndrome (ACS). A 50-year-old female developed persistent chest discomfort related to anterior STEMI. After an unsuccessful thrombolysis attempt, due to delay concern, the patient was then sent to the catheterization laboratory for rescue PCI. The coronary angiogram revealed a TIMI 3 flow proximal LAD significant stenosis with spastic appearance of the coronary arteries which has improved after intracoronary nitrates administration. Optical Coherence Tomography (OCT) excluded coronary artery dissection and haematoma also revealed thrombus on moderate atherosclerotic plaque. The patient was then pain-free;she was managed medically and discharged after few days of monitoring. Three weeks later, she developed transient chest pain with ST segment elevation while cycling during rehabilitation program. Provocation test by Ergonovine was positive with complete occlusion of proximal RCA (right coronary artery) complicated by transient complete heart block and shock. She was stabilized with 7 mg of intracoronary nitrates injection. She was discharged after close monitoring with calcium channel blocker and tobacco cessation. ACS may complicate prolonged coronary artery vasospasm making the diagnosis challenging. OCT may help understand ACS mechanism and exclude spontaneous coronary artery dissection. Provocation test is crucial for confirmation.
文摘目的基于质性研究meta整合收集稳定型心绞痛患者的体验和感受。方法检索中国知网、万方数据知识服务平台、维普网、SinoMed、PubMed、EMbase、The Cochrane Library、澳大利亚乔安娜布里格斯研究所、EBSCO和Web of Science核心合集数据库中关于稳定型心绞痛患者体验和感受的质性研究或混合研究,检索时限为建库至2024年3月。2名调查员进行独立文献筛选、数据提取和文献质量评价,使用汇集性整合方法整合结果,并使用CERQual对整合结果信度进行分级。结果共纳入7篇文献,提炼出20个主题,最终归纳为8个类别并形成3个整合结果,分别是多维度影响患者生活质量、患者对当前接受治疗的看法及患者存在未满足的临床需求。结论稳定型心绞痛广泛影响患者的生活、心理和社会功能,应探索以患者为中心的医疗管理模式,充分了解患者感受和需求,并将其纳入未来的医疗决策。由于研究的局限性,未来应在国内开展高质量的质性研究,收集中国稳定型心绞痛患者的体验和感受。
文摘目的:探讨注射用丹参多酚酸盐治疗高龄冠心病心绞痛病人的临床疗效观察及其对血脂、B型钠尿肽(Brain natriuretic,BNP)、C型反应性蛋白(C-reactive protein,CRP)的影响。方法:选取2016-01~2016-08期间于内蒙古自治区人民医院干部保健所住院的高龄冠心病心绞痛病人64例,按随机原则分为治疗组(37例)和对照组(25例)。对照组给予常规抗心肌缺血治疗,治疗组给予注射用丹参多酚酸盐联合常规药物治疗。观察2wk后两组病人的心绞痛症状、心电图、血脂、BNP、CRP的改善情况。结果:两组病人的心绞痛症状、心电图、血脂、BNP、CRP均比治疗前改善明显,差异均有统计学意义(P<0.05);治疗后高密度脂蛋白(high density lipoproteins,HDL)、左室射血分数(left vertricular ejection fraction,LVEF)水平均较治疗前有明显升高,差异均有统计学意义(P<0.05);治疗组治疗后甘油三酯(Triglyceride,TG)、后清总胆固醇(serum total cholesterd,TC)、低密度脂蛋白(low density lipoprotein,LDL)、C型反应性蛋白(C-reactive protein,CRP)、BNP水平较对照组下降更明显(P<0.05),治疗组治疗后HDL、LVEF水平较对照组升高更明显(P<0.05)。结论:注射用丹参多酚酸盐能显著提高高龄冠心病心绞痛病人的临床疗效及改善BNP、CRP、血脂水平。
