Infections caused by gastrointestinal nematodes are major threats to livestock industry in the developing countries. They cause direct effects in form of loss in production and indirect economic losses due to high cos...Infections caused by gastrointestinal nematodes are major threats to livestock industry in the developing countries. They cause direct effects in form of loss in production and indirect economic losses due to high cost of anthelmintic drugs. Various alternative strategies are in practice to control parasitism which includes the usage of medicinal plants. This study evaluates the in situ anthelminthic activity of Bidens pilosa ethanolic extract on gastro-intestinal strongyles of small ruminants. Twenty (20) naturally infested goats of both sexes were distributed into 5 groups (n = 4) corresponding to groups receiving Tween 80 at 2.8%, Albendazole at 5 mg/kg and the three doses of extract (125, 250 and 500 mg/kg). The doses of extract and 2.8% Tween 80 were administered twice daily for 3 consecutive days while Albendazole was administered in a single dose. Faecal eggs count reduction, body weight, packed cell volume (PCV) and total worm count reduction were determined. Results showed that the ethanolic extract of B. pilosa was not effective against adult worms while Albendozole inflicted a 100% reduction of eggs count and total worm count of digestive strongyle. Body weight and PCV remain almost constant. This study indicates that ethanolic extract of B. pilosa at tested doses has no anthelminthic activity. However, further optimization and standardization of the ethanolic extract of B. pilosa could enhance its anthelminthic activity.展开更多
To test effect of a synthetic Aluminium-Magnesium Silicate (AMS) on anthelmintic efficacy of piperazine citrate (PC), 35 mice were infected by dosing each, 0.15 ml Helignosomoides bakeri sample which contained 200 inf...To test effect of a synthetic Aluminium-Magnesium Silicate (AMS) on anthelmintic efficacy of piperazine citrate (PC), 35 mice were infected by dosing each, 0.15 ml Helignosomoides bakeri sample which contained 200 infective larvae, per os. Following comfirmation of establishment of infection by faecal floatation, they were assigned into seven groups of 5 each, and were treated with piperazine citrate, per os, at rates of 110 mg/kg (PC), 110 mg/kg (PC in AMS), 82.5 mg/kg (PC), 82.5 mg/kg (PC in AMS), 55 mg/kg (PC) and 55 mg/kg (PC in AMS) respectively. The seventh group served as untreated control. Mean Eggs Per Gramm of faeces (EPG) were 375 ± 32.27, 175 ± 14.43, 830 ± 1.04, 70 ± 12.25, 850 ± 293.06, 370 ± 58.54 and 2,200 ± 2.55 respectively. This showed EPG reduction rates of 83%, 92%, 62%, 97%, 61% and 83% among the respective treated groups.展开更多
Xylopia aethiopica dried fruits （gains of selim） as an additive in starter broilers production was investigated. For this purpose, a total of 195-day old broiler chicks （Arbor acres） were randomly allocated into f...Xylopia aethiopica dried fruits （gains of selim） as an additive in starter broilers production was investigated. For this purpose, a total of 195-day old broiler chicks （Arbor acres） were randomly allocated into five treatments groups with 39 chicks and three replicates of 13 chicks in each. Blended grains of selim was given through drinking water on treatments T2, T3, T4 and T5 at concentrations of 0.4, 0.6, 0.8 and 1,0 g/L, while chicks on treatment T1 （control） received antibiotics （Doxy-gen 20/20 WSP： Doxycycline hyclate 200 mg and Gentamicine sulfate 200 mg） at 0.3 g/L of water. All the experimental chicks were fed ad libitum with diet containing 23% crude protein and 2,851.55 kcal/kg metabolizable energy for 28 d. The results revealed that there were similarities （P 〉 0.05） in final body weight, total weight gain, daily weight gain, total feed intake, daily feed intake and feed conversion ratio among the treatments. There were significant （P 〈 0.05） differences in the microbial count of faeces before the birds received antibiotics and grains of selim, but count were similar （P 〉 0.05） after grains of selim and antibiotics were administered. Cost of total feed consumed, cost of per kg feed and cost of per kg weight were significantly （P 〈 0.05） higher in treatment T1, but cost differential and relative cost benefit were similar （P 〉 0.05）. Results indicate that grains of selim have antimicrobial and anthelminthic properties, and promote growth in broiler chickens.展开更多
文摘Infections caused by gastrointestinal nematodes are major threats to livestock industry in the developing countries. They cause direct effects in form of loss in production and indirect economic losses due to high cost of anthelmintic drugs. Various alternative strategies are in practice to control parasitism which includes the usage of medicinal plants. This study evaluates the in situ anthelminthic activity of Bidens pilosa ethanolic extract on gastro-intestinal strongyles of small ruminants. Twenty (20) naturally infested goats of both sexes were distributed into 5 groups (n = 4) corresponding to groups receiving Tween 80 at 2.8%, Albendazole at 5 mg/kg and the three doses of extract (125, 250 and 500 mg/kg). The doses of extract and 2.8% Tween 80 were administered twice daily for 3 consecutive days while Albendazole was administered in a single dose. Faecal eggs count reduction, body weight, packed cell volume (PCV) and total worm count reduction were determined. Results showed that the ethanolic extract of B. pilosa was not effective against adult worms while Albendozole inflicted a 100% reduction of eggs count and total worm count of digestive strongyle. Body weight and PCV remain almost constant. This study indicates that ethanolic extract of B. pilosa at tested doses has no anthelminthic activity. However, further optimization and standardization of the ethanolic extract of B. pilosa could enhance its anthelminthic activity.
文摘To test effect of a synthetic Aluminium-Magnesium Silicate (AMS) on anthelmintic efficacy of piperazine citrate (PC), 35 mice were infected by dosing each, 0.15 ml Helignosomoides bakeri sample which contained 200 infective larvae, per os. Following comfirmation of establishment of infection by faecal floatation, they were assigned into seven groups of 5 each, and were treated with piperazine citrate, per os, at rates of 110 mg/kg (PC), 110 mg/kg (PC in AMS), 82.5 mg/kg (PC), 82.5 mg/kg (PC in AMS), 55 mg/kg (PC) and 55 mg/kg (PC in AMS) respectively. The seventh group served as untreated control. Mean Eggs Per Gramm of faeces (EPG) were 375 ± 32.27, 175 ± 14.43, 830 ± 1.04, 70 ± 12.25, 850 ± 293.06, 370 ± 58.54 and 2,200 ± 2.55 respectively. This showed EPG reduction rates of 83%, 92%, 62%, 97%, 61% and 83% among the respective treated groups.
文摘Xylopia aethiopica dried fruits （gains of selim） as an additive in starter broilers production was investigated. For this purpose, a total of 195-day old broiler chicks （Arbor acres） were randomly allocated into five treatments groups with 39 chicks and three replicates of 13 chicks in each. Blended grains of selim was given through drinking water on treatments T2, T3, T4 and T5 at concentrations of 0.4, 0.6, 0.8 and 1,0 g/L, while chicks on treatment T1 （control） received antibiotics （Doxy-gen 20/20 WSP： Doxycycline hyclate 200 mg and Gentamicine sulfate 200 mg） at 0.3 g/L of water. All the experimental chicks were fed ad libitum with diet containing 23% crude protein and 2,851.55 kcal/kg metabolizable energy for 28 d. The results revealed that there were similarities （P 〉 0.05） in final body weight, total weight gain, daily weight gain, total feed intake, daily feed intake and feed conversion ratio among the treatments. There were significant （P 〈 0.05） differences in the microbial count of faeces before the birds received antibiotics and grains of selim, but count were similar （P 〉 0.05） after grains of selim and antibiotics were administered. Cost of total feed consumed, cost of per kg feed and cost of per kg weight were significantly （P 〈 0.05） higher in treatment T1, but cost differential and relative cost benefit were similar （P 〉 0.05）. Results indicate that grains of selim have antimicrobial and anthelminthic properties, and promote growth in broiler chickens.
