A new polyhydroxysteroidal glycoside, (20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-24-ethyl- 5α-cholest-8(14)-en-313,613,713,16α-tetrol (anthenoside A, 1), was isolated from the star...A new polyhydroxysteroidal glycoside, (20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-24-ethyl- 5α-cholest-8(14)-en-313,613,713,16α-tetrol (anthenoside A, 1), was isolated from the starfish Anthenea chinensis. Its structure was elucidated by extensive spectral analysis and chemical evidences. 1 exhibited significant cytotoxicity against human tumor K-562, BEL-7402 and U87MG cells.展开更多
基金the National Natural Science Foundation of China(No.20502035)the National High-Tech Research and Development Project(No.2006AA09Z423)
文摘A new polyhydroxysteroidal glycoside, (20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-24-ethyl- 5α-cholest-8(14)-en-313,613,713,16α-tetrol (anthenoside A, 1), was isolated from the starfish Anthenea chinensis. Its structure was elucidated by extensive spectral analysis and chemical evidences. 1 exhibited significant cytotoxicity against human tumor K-562, BEL-7402 and U87MG cells.