Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients...Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.展开更多
BACKGROUND Recurrent hepatocellular carcinoma(rHCC)is a common outcome after curative treatment.Retreatment for rHCC is recommended,but no guidelines exist.AIM To compare curative treatments such as repeated hepatecto...BACKGROUND Recurrent hepatocellular carcinoma(rHCC)is a common outcome after curative treatment.Retreatment for rHCC is recommended,but no guidelines exist.AIM To compare curative treatments such as repeated hepatectomy(RH),radiofrequency ablation(RFA),transarterial chemoembolization(TACE)and liver transplantation(LT)for patients with rHCC after primary hepatectomy by conducting a network meta-analysis(NMA).METHODS From 2011 to 2021,30 articles involving patients with rHCC after primary liver resection were retrieved for this NMA.The Q test was used to assess heterogeneity among studies,and Egger’s test was used to assess publication bias.The efficacy of rHCC treatment was assessed using disease-free survival(DFS)and overall survival(OS).RESULTS From 30 articles,a total of 17,11,8,and 12 arms of RH,RFA,TACE,and LT subgroups were collected for analysis.Forest plot analysis revealed that the LT subgroup had a better cumulative DFS and 1-year OS than the RH subgroup,with an odds ratio(OR)of 0.96(95%CI:0.31-2.96).However,the RH subgroup had a better 3-year and 5-year OS compared to the LT,RFA,and TACE subgroups.Hierarchic step diagram of different subgroups measured by the Wald test yielded the same results as the forest plot analysis.LT had a better 1-year OS(OR:1.04,95%CI:0.34-03.20),and LT was inferior to RH in 3-year OS(OR:10.61,95%CI:0.21-1.73)and 5-year OS(OR:0.95,95%CI:0.39-2.34).According to the predictive P score evaluation,the LT subgroup had a better DFS,and RH had the best OS.However,meta-regression analysis revealed that LT had a better DFS(P<0.001)as well as 3-year OS(P=0.881)and 5-year OS(P=0.188).The differences in superiority between DFS and OS were due to the different testing methods used.CONCLUSION According to this NMA,RH and LT had better DFS and OS for rHCC than RFA and TACE.However,treatment strategies should be determined by the recurrent tumor characteristics,the patient’s general health status,and the care program at each institution.展开更多
Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock engineering.In this study,F...Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock engineering.In this study,Fangshan granite(FG)specimens were exposed to microwave irradiation and heat treatment.The damage of FG specimens induced by these two methods was compared using X-ray CT scanning and ultrasonic wave method.The temperatures of FG after microwave irradiation and thermal treatment were effectively evaluated using a newly proposed technique.A novelty method for precisely determining the geometric features of fragments is developed to estimate the fragmentation energy.Thus,the dynamic uniaxial compressive strength(UCS),the dynamic fragmentation characteristics,and the fragmentation energy of FG after these two pretreatment methods can be reasonably compared.The noticeable distinction of loading rate effect on the dynamic UCS of FG between these two pretreatment methods is first observed.A relationship is established between the dynamic UCS and the damage induced by microwave irradiation and heat treatment.Moreover,fragmentation energy fan analysis is introduced to accurately compare the fragmentation properties of FG after two pretreatment methods in dynamic compression tests.展开更多
BACKGROUND Diabetic foot ulcers(DFUs)are a common complication of diabetes,often leading to severe infections,amputations,and reduced quality of life.The current standard treatment protocols for DFUs have limitations ...BACKGROUND Diabetic foot ulcers(DFUs)are a common complication of diabetes,often leading to severe infections,amputations,and reduced quality of life.The current standard treatment protocols for DFUs have limitations in promoting efficient wound healing and preventing complications.A comprehensive treatment approach targeting multiple aspects of wound care may offer improved outcomes for patients with DFUs.The hypothesis of this study is that a comprehensive treatment protocol for DFUs will result in faster wound healing,reduced amputation rates,and improved overall patient outcomes compared to standard treatment protocols.AIM To compare the efficacy and safety of a comprehensive treatment protocol for DFUs with those of the standard treatment protocol.METHODS This retrospective study included 62 patients with DFUs,enrolled between January 2022 and January 2024,randomly assigned to the experimental(n=32)or control(n=30)group.The experimental group received a comprehensive treatment comprising blood circulation improvement,debridement,vacuum sealing drainage,recombinant human epidermal growth factor and anti-inflammatory dressing,and skin grafting.The control group received standard treatment,which included wound cleaning and dressing,antibiotics administration,and surgical debridement or amputation,if necessary.Time taken to reduce the white blood cell count,number of dressing changes,wound healing rate and time,and amputation rate were assessed.RESULTS The experimental group exhibited significantly better outcomes than those of the control group in terms of the wound healing rate,wound healing time,and amputation rate.Additionally,the comprehensive treatment protocol was safe and well tolerated by the patients.CONCLUSION Comprehensive treatment for DFUs is more effective than standard treatment,promoting granulation tissue growth,shortening hospitalization time,reducing pain and amputation rate,improving wound healing,and enhancing quality of life.展开更多
The effect of cooling rate of the solidification process on the following solution heat treatment of A356 alloy was investigated,where the cooling rates of 96 K/s and 3 K/s were obtained by the step-like metal mold.Th...The effect of cooling rate of the solidification process on the following solution heat treatment of A356 alloy was investigated,where the cooling rates of 96 K/s and 3 K/s were obtained by the step-like metal mold.Then the eutectic silicon morphology evolution and tensile properties of the alloy samples were observed and analyzed after solution heat treatment at 540 °C for different time.The results show that the high cooling rate of the solidification process can not only reduce the solid solution heat treatment time to rapidly modify the eutectic silicon morphology,but also improve the alloy tensile properties.Specially,it is found that the disintegration,the spheroidization and coarsening of eutectic silicon of A356 alloy are completed during solution heat treatment through two stages,i.e.,at first,the disintegration and spheroidization of the eutectic silicon mainly takes place,then the eutectic silicon will coarsen.展开更多
Objective: To assess the curative effect of the stage II femoral head necrosis treated by arthroscopy assisted lesion clearance, bone graft and titanium rod support. Methods: All the patients (including 58 patients 74...Objective: To assess the curative effect of the stage II femoral head necrosis treated by arthroscopy assisted lesion clearance, bone graft and titanium rod support. Methods: All the patients (including 58 patients 74 hips) were diagnosed as stage II femoral head necrosis according to the ARCO staging system during 2003-2013. In these patients, 15 hips were stage IIA, 34 hips were stage IIB and 25 hips were stage IIC. Located by C-arm and assisted by arthroscopy, minimally-invasive percutaneous pulp core decompression and lesion clearance within the femoral head were accurately performed, and then, the OAM composite of autologous bone marrow was implanted and the femoral head was supported using the titanium rod. Follow-up including the pain score, the Harris hip score and X-ray observation for disease progression were achieved at 6, 12, 24 and 36 months postoperatively, Kaplan-Meier survival curve was used for the survival analysis. Result: The VAS score and the Harris score after operation were better THRAn THRAt of before the surgery, the difference had statistical significance (p Conclusion: Arthroscopy assisted lesion clearance, bone graft and titanium rod support to treat the stage II osteonecrosis of the femoral head are effective and can prevent the femoral head from collapsing. But for stage IIC patients who had a history of the use of hormone, this surgery should be chosen carefully because the outcome is always very poor.展开更多
High Rate Algal Pond (HRAP) was constructed and operated using a mixer device to investigate its capability in treating greywater for reuse in gardening. Physico-chemical and microbiological parameters were monitored....High Rate Algal Pond (HRAP) was constructed and operated using a mixer device to investigate its capability in treating greywater for reuse in gardening. Physico-chemical and microbiological parameters were monitored. With a hydraulic retention time of 7.5 days and a solid retention time of 20 days, the average removal efficiencies (ARE) were 69% and 62% for BOD5 and COD respectively. The ARE for , and were 23%, 52% and 43% respectively. The removal of suspended solids (SS) was unsatisfactory, which could be attributed to the low average algal settling efficiencies of 9.3% and 16.0% achieved after 30 and 60 minutes respectively. The ARE of fecal coliforms, Escherichia coli and enterococci were 2.65, 3.14 and 3.17 log units respectively. In view of the results, the HRAP technology could be adapted for greywater treatment in sahelian regions. However, further studies on the diversity of the algal species growing in the HRAP unit are necessary in order to increase the removal of SS. Hazards of a reuse of the effluents are discussed on the basis of the various qualitative parameters. The residual content of E. coli was varying from 4 CFU per 100 mL. Based on WHO guidelines for greywater reuse in irrigation, the effluents could be used for restricted irrigation (E. coli < 105 CFU per 100 mL). Furthermore, the reuse potential is discussed on the basis of FAO guidelines using SAR (3.03 to 4.11), electrical conductivity (482 to 4500 μS/cm) and pH values (6.45 to 8.6).展开更多
Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient’s state, which are limited by medical resources and organizationa...Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient’s state, which are limited by medical resources and organizational problems. The development of new medical technologies provides a better and effective non-surgical treatment of acute MI and increases long-term prognosis in this category of patients. The study aims to investigate the influence of hyperbaric oxygenation treatment on clinical outcomes (survival rate and recurrent myocardial infarction (rMI)) during the five-year period of monitoring. The study involved 697 patients who suffered from acute MI, having undergone the standard treatment. The patients were randomly divided into two groups: Group 1 (reference, n = 363);Group 2 (test, n = 334). Patients of Group 2 were given the traditional treatment, accompanied with HBOT (isopression for forty minutes at a working pressure of 0.03 MPa). HBOT was applied first through the fifth day following MI. The treatment course included six cycles, once per day. The clinical assessment was focused on clinical outcome: rMI and mortality related to cardiovascular events. HBOT application that accompanied the acute MI with traditional pharmacotherapy has been proved to reduce rMI within five years following inpatient discharge (rMI rate was 14% in the reference group and 5.4% in the test group, χ2 = 13.3, р < 0.05). The combination of HBOT with traditional methods in treating acute MI makes it possible to raise the five-year survival rate from 84.4% up to 95.9%.展开更多
Evaluating the outcomes of DOTS program is essential for recognizing and amending system failures before the incidence and proportion of resistant isolates rise. In this study, we seek to evaluate the impact of DOTS s...Evaluating the outcomes of DOTS program is essential for recognizing and amending system failures before the incidence and proportion of resistant isolates rise. In this study, we seek to evaluate the impact of DOTS strategy on tuberculosis treatment success rate in Dabat, northwest Ethiopia. Medical records of 1305 pulmonary and extrapulmonary tuberculosis patients registered from 2007 to 2012 at two health centers in Dabat district, northwest Ethiopia, were reviewed. Treatment outcomes and forms of tuberculosis were assessed according to WHO guidelines. Descriptive analyses were performed using frequencies and percentages. Treatment success rate was observed in 1146 (87.8%) patients. Out of these, 534 (89.1%) of the males and 612 (86.7%) of the females were successfully treated. It was also true in 338 (87.8%) of the smear-positive pulmonary tuberculosis patients, 473 (85.7%) of the smear-negative pulmonary tuberculosis patients, and 335 (91.0%) of the extrapulmonary tuberculosis patients. In conclusion, treatment success rate in the current study was slightly higher than the WHO international updated target for the period 2011 to 2015. However, this doesn’t mean that there will be no need for further enhancement of supervision and monitoring techniques, strengthening counseling and health education programs, and improving the quality of laboratory diagnostic services.展开更多
Comparative investigations were carried out of the effect of heat treatment regimes Jor steel GC-4(40CrMnSiMoVA)on its crack propagating rates,from corrosion fatigue, (da/dN)_(CF),or stress corrosion cracking,(da/dt)_...Comparative investigations were carried out of the effect of heat treatment regimes Jor steel GC-4(40CrMnSiMoVA)on its crack propagating rates,from corrosion fatigue, (da/dN)_(CF),or stress corrosion cracking,(da/dt)_(SCC),in media with various constituents and pH values.Both(da/dN)_(CF) and(da/dt)_(SCC) accelerate with the increase of yield stress of the steel,yet the former is far less than the later.In comparison with media,the (da/dt)_(SCC) in distilled water is slightly greater than that in 3.5% NaCl solution,and the (da/dN)_(CF) in distilled water is far less than that in 3.5% NaCl solution.With the pH value increasing in 3.5% NaCl solution,the(da/dN)_(CF) lowers down and the(da/dt)_(SCC) speeds up.An explanation was also proposed with concept of the cyclic hardening and softening at crack tip,as well as the crack closure and occluded cell effect.展开更多
Surface-treated MmNi3.55Co0.75Mn0.4Al0.3 alloy as negative electrode material of nickel-metal hydride battery was employed to improve the high-rate dischargeability. Surface treatment was realized by dipping and stirr...Surface-treated MmNi3.55Co0.75Mn0.4Al0.3 alloy as negative electrode material of nickel-metal hydride battery was employed to improve the high-rate dischargeability. Surface treatment was realized by dipping and stirring the alloy into a HCl aqueous solution with various concentrations at room temperature. The microstructure of the alloy before and after surface treatment was analyzed by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The electrochemical properties before and after surface treatment were compared, and the alloy treated in 0.025 mol/L HCl solution showed the optimal high-rate dischargeability.展开更多
We consider a SIR epidemic model with saturated incidence rate and treatment. We show that if the basic reproduction number, R0 is less than unity and the disease free equilibrium is locally asymptotically stable. Mor...We consider a SIR epidemic model with saturated incidence rate and treatment. We show that if the basic reproduction number, R0 is less than unity and the disease free equilibrium is locally asymptotically stable. Moreover, we show that if R0 > 1, the endemic equilibrium is locally asymptotically stable. In the end, we give some numerical results to compare our model with existing model and to show the effect of the treatment term on the model.展开更多
Lab scale biological treatment system was constructed from acrylic and operated using synthetic wastewater to evaluate the nitrification performance using different media. The media used for were Ceramic Ring A (CRA...Lab scale biological treatment system was constructed from acrylic and operated using synthetic wastewater to evaluate the nitrification performance using different media. The media used for were Ceramic Ring A (CRA), Ceramic Ring B (CRB), Japanese Filter Mat (JFM), and Filter Wool (FW). Laboratory studies were conducted, in order to evaluate the nitrification performance of different media types, at different synthetic wastewater flow rates, ranging from 0.03 to 0.045 m3/hr. The results from experiments suggest that at higher water flow rates, there was a decrease in nitrification for all media types. Based on the ammonia and nitrite removal rates, FW media gave the optimum nitrification, of up to 0.46 g/m2/day and 0.09 g/m2/day, respectively. Besides, in this study, the surface texture of the media is the main factor that affected the volumetric ammonia and nitrite conversion rates (VTR and VNR). JFM gave the greatest VTR and VNR performance, compared with the other media展开更多
A set of techniques for well treatment aimed to enhance oil recovery are considered in the present study.These are based on the application of elastic waves of various types(dilation-wave,vibro-wave,or other acoustica...A set of techniques for well treatment aimed to enhance oil recovery are considered in the present study.These are based on the application of elastic waves of various types(dilation-wave,vibro-wave,or other acoustically induced effects).In such a context,a new technique is proposed to predict the effectiveness of the elastic-wave well treatment using the rank distribution according to Zipf’s law.It is revealed that,when the results of elastic wave well treatments are analyzed,groups of wells exploiting various geological deposits can differ in terms of their slope coefficients and free members.As the slope coefficient increases,the average increase in the well oil production rate(after the well treatment)becomes larger.An equation is obtained accordingly for estimating the slope coefficient in the Zipf’s equation from the frequency of the elastic wave.The obtained results demonstrate the applicability of the Zipf’s law in the analysis of the technological efficiency of elastic-wave well treatment methods.展开更多
BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medicati...BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medication compromises treatment outcomes and prolongs the recovery of patients’social functioning.AIM To evaluate the effect of non-pharmacological treatment on the full recovery of social functioning in patients with ADHD.METHODS A total of 90 patients diagnosed with ADHD between May 2019 and August 2020 were included in the study and randomly assigned to either the pharmacological group(methylphenidate hydrochloride and tomoxetine hydrochloride)or the non-pharmacological group(parental training,behavior modification,sensory integration therapy,and sand tray therapy),with 45 cases in each group.Outcome measures included treatment compliance,Swanson,Nolan,and Pelham,Version IV(SNAP-IV)scores,Conners Parent Symptom Questionnaire(PSQ)scores,and Weiss Functional Impairment Rating Scale(WFIRS)scores.RESULTS The non-pharmacological interventions resulted in significantly higher compliance in patients(95.56%)compared with medication(71.11%)(P<0.05).However,no significant differences in SNAP-IV and PSQ scores,in addition to the learning/school,social activities,and adventure activities of the WFIRS scores were observed between the two groups(P>0.05).Patients with non-pharmacological interventions showed higher WFIRS scores for family,daily life skills,and self-concept than those in the pharmacological group(P<0.05).CONCLUSION Non-pharmacological interventions,in contrast to the potential risks of adverse events after longterm medication,improve patient treatment compliance,alleviate patients’behavioral symptoms of attention,impulsivity,and hyperactivity,and improve their cognitive ability,thereby improving family relationships and patient self-evaluation.展开更多
Objective:To observe whether the Ear Well infant ear correction system makes any difference in terms of the treatment effect,duration,complication rate,and nursing care requirements in different types of infant auricl...Objective:To observe whether the Ear Well infant ear correction system makes any difference in terms of the treatment effect,duration,complication rate,and nursing care requirements in different types of infant auricle deformities.Methods:A total of 93 infant patients with auricular deformity(age:<3 months of age)who were diagnosed and treated in Guangzhou Children and Women’s Medical Center from April 2018 to September 2020 were selected and treated with the Ear Well infant ear correction system.We observed and recorded the effects of the Ear Well infant ear correction system,the treatment duration,the number of rebound cases,and complications that are likely to occur during treatment,and noted the related factors causing complications and the relative requirements for nursing care.Results:The Earwell infant ear correction system could effectively correct infant auricle deformities.Among the 93 cases,90 cases had positive therapeutical outcome and the effective rate was 96.77%.The treatment duration for lop ear and protruding ear was longer than for other auricle deformities;the deformity recoil and the treatment compilation rates were much higher for these 2 deformity types,and the difference was statistically significant(P<0.05).Conclusions:The treatment suggestion for the wearing duration of the Ear Well infant ear correction system for lop ear and protruding ear is a prolonged duration compared with that for other infant auricle deformities.Fur ther,the requirements for nursing care intensity and infant patient’s guardian’s nursing knowledge and skill are obviously increased for these 2 types of auricle deformities.展开更多
文摘Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.
基金Supported by the Research Fund from E-Da Hospital,No.EDAHS110012.
文摘BACKGROUND Recurrent hepatocellular carcinoma(rHCC)is a common outcome after curative treatment.Retreatment for rHCC is recommended,but no guidelines exist.AIM To compare curative treatments such as repeated hepatectomy(RH),radiofrequency ablation(RFA),transarterial chemoembolization(TACE)and liver transplantation(LT)for patients with rHCC after primary hepatectomy by conducting a network meta-analysis(NMA).METHODS From 2011 to 2021,30 articles involving patients with rHCC after primary liver resection were retrieved for this NMA.The Q test was used to assess heterogeneity among studies,and Egger’s test was used to assess publication bias.The efficacy of rHCC treatment was assessed using disease-free survival(DFS)and overall survival(OS).RESULTS From 30 articles,a total of 17,11,8,and 12 arms of RH,RFA,TACE,and LT subgroups were collected for analysis.Forest plot analysis revealed that the LT subgroup had a better cumulative DFS and 1-year OS than the RH subgroup,with an odds ratio(OR)of 0.96(95%CI:0.31-2.96).However,the RH subgroup had a better 3-year and 5-year OS compared to the LT,RFA,and TACE subgroups.Hierarchic step diagram of different subgroups measured by the Wald test yielded the same results as the forest plot analysis.LT had a better 1-year OS(OR:1.04,95%CI:0.34-03.20),and LT was inferior to RH in 3-year OS(OR:10.61,95%CI:0.21-1.73)and 5-year OS(OR:0.95,95%CI:0.39-2.34).According to the predictive P score evaluation,the LT subgroup had a better DFS,and RH had the best OS.However,meta-regression analysis revealed that LT had a better DFS(P<0.001)as well as 3-year OS(P=0.881)and 5-year OS(P=0.188).The differences in superiority between DFS and OS were due to the different testing methods used.CONCLUSION According to this NMA,RH and LT had better DFS and OS for rHCC than RFA and TACE.However,treatment strategies should be determined by the recurrent tumor characteristics,the patient’s general health status,and the care program at each institution.
基金supported by the National Natural Science Foundation of China(Nos.51879184 and 12172253).
文摘Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock engineering.In this study,Fangshan granite(FG)specimens were exposed to microwave irradiation and heat treatment.The damage of FG specimens induced by these two methods was compared using X-ray CT scanning and ultrasonic wave method.The temperatures of FG after microwave irradiation and thermal treatment were effectively evaluated using a newly proposed technique.A novelty method for precisely determining the geometric features of fragments is developed to estimate the fragmentation energy.Thus,the dynamic uniaxial compressive strength(UCS),the dynamic fragmentation characteristics,and the fragmentation energy of FG after these two pretreatment methods can be reasonably compared.The noticeable distinction of loading rate effect on the dynamic UCS of FG between these two pretreatment methods is first observed.A relationship is established between the dynamic UCS and the damage induced by microwave irradiation and heat treatment.Moreover,fragmentation energy fan analysis is introduced to accurately compare the fragmentation properties of FG after two pretreatment methods in dynamic compression tests.
基金Supported by General Medical Research Fund Project,No.TYYLKYJJ-2022-021.
文摘BACKGROUND Diabetic foot ulcers(DFUs)are a common complication of diabetes,often leading to severe infections,amputations,and reduced quality of life.The current standard treatment protocols for DFUs have limitations in promoting efficient wound healing and preventing complications.A comprehensive treatment approach targeting multiple aspects of wound care may offer improved outcomes for patients with DFUs.The hypothesis of this study is that a comprehensive treatment protocol for DFUs will result in faster wound healing,reduced amputation rates,and improved overall patient outcomes compared to standard treatment protocols.AIM To compare the efficacy and safety of a comprehensive treatment protocol for DFUs with those of the standard treatment protocol.METHODS This retrospective study included 62 patients with DFUs,enrolled between January 2022 and January 2024,randomly assigned to the experimental(n=32)or control(n=30)group.The experimental group received a comprehensive treatment comprising blood circulation improvement,debridement,vacuum sealing drainage,recombinant human epidermal growth factor and anti-inflammatory dressing,and skin grafting.The control group received standard treatment,which included wound cleaning and dressing,antibiotics administration,and surgical debridement or amputation,if necessary.Time taken to reduce the white blood cell count,number of dressing changes,wound healing rate and time,and amputation rate were assessed.RESULTS The experimental group exhibited significantly better outcomes than those of the control group in terms of the wound healing rate,wound healing time,and amputation rate.Additionally,the comprehensive treatment protocol was safe and well tolerated by the patients.CONCLUSION Comprehensive treatment for DFUs is more effective than standard treatment,promoting granulation tissue growth,shortening hospitalization time,reducing pain and amputation rate,improving wound healing,and enhancing quality of life.
基金Project(3102014KYJD002)supported by the Fundamental Research Funds for the Central Universities of ChinaProjects(50901059,51431008,51134011)supported by the National Natural Science Foundation of China+2 种基金Project(2011CB610403)supported by the National Basic Research Program of ChinaProject(51125002)supported by the China National Funds for Distinguished Young ScientistsProject(JC20120223)supported by the Fundamental Research Fund of Northwestern Polytechnical University,China
文摘The effect of cooling rate of the solidification process on the following solution heat treatment of A356 alloy was investigated,where the cooling rates of 96 K/s and 3 K/s were obtained by the step-like metal mold.Then the eutectic silicon morphology evolution and tensile properties of the alloy samples were observed and analyzed after solution heat treatment at 540 °C for different time.The results show that the high cooling rate of the solidification process can not only reduce the solid solution heat treatment time to rapidly modify the eutectic silicon morphology,but also improve the alloy tensile properties.Specially,it is found that the disintegration,the spheroidization and coarsening of eutectic silicon of A356 alloy are completed during solution heat treatment through two stages,i.e.,at first,the disintegration and spheroidization of the eutectic silicon mainly takes place,then the eutectic silicon will coarsen.
文摘Objective: To assess the curative effect of the stage II femoral head necrosis treated by arthroscopy assisted lesion clearance, bone graft and titanium rod support. Methods: All the patients (including 58 patients 74 hips) were diagnosed as stage II femoral head necrosis according to the ARCO staging system during 2003-2013. In these patients, 15 hips were stage IIA, 34 hips were stage IIB and 25 hips were stage IIC. Located by C-arm and assisted by arthroscopy, minimally-invasive percutaneous pulp core decompression and lesion clearance within the femoral head were accurately performed, and then, the OAM composite of autologous bone marrow was implanted and the femoral head was supported using the titanium rod. Follow-up including the pain score, the Harris hip score and X-ray observation for disease progression were achieved at 6, 12, 24 and 36 months postoperatively, Kaplan-Meier survival curve was used for the survival analysis. Result: The VAS score and the Harris score after operation were better THRAn THRAt of before the surgery, the difference had statistical significance (p Conclusion: Arthroscopy assisted lesion clearance, bone graft and titanium rod support to treat the stage II osteonecrosis of the femoral head are effective and can prevent the femoral head from collapsing. But for stage IIC patients who had a history of the use of hormone, this surgery should be chosen carefully because the outcome is always very poor.
文摘High Rate Algal Pond (HRAP) was constructed and operated using a mixer device to investigate its capability in treating greywater for reuse in gardening. Physico-chemical and microbiological parameters were monitored. With a hydraulic retention time of 7.5 days and a solid retention time of 20 days, the average removal efficiencies (ARE) were 69% and 62% for BOD5 and COD respectively. The ARE for , and were 23%, 52% and 43% respectively. The removal of suspended solids (SS) was unsatisfactory, which could be attributed to the low average algal settling efficiencies of 9.3% and 16.0% achieved after 30 and 60 minutes respectively. The ARE of fecal coliforms, Escherichia coli and enterococci were 2.65, 3.14 and 3.17 log units respectively. In view of the results, the HRAP technology could be adapted for greywater treatment in sahelian regions. However, further studies on the diversity of the algal species growing in the HRAP unit are necessary in order to increase the removal of SS. Hazards of a reuse of the effluents are discussed on the basis of the various qualitative parameters. The residual content of E. coli was varying from 4 CFU per 100 mL. Based on WHO guidelines for greywater reuse in irrigation, the effluents could be used for restricted irrigation (E. coli < 105 CFU per 100 mL). Furthermore, the reuse potential is discussed on the basis of FAO guidelines using SAR (3.03 to 4.11), electrical conductivity (482 to 4500 μS/cm) and pH values (6.45 to 8.6).
文摘Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient’s state, which are limited by medical resources and organizational problems. The development of new medical technologies provides a better and effective non-surgical treatment of acute MI and increases long-term prognosis in this category of patients. The study aims to investigate the influence of hyperbaric oxygenation treatment on clinical outcomes (survival rate and recurrent myocardial infarction (rMI)) during the five-year period of monitoring. The study involved 697 patients who suffered from acute MI, having undergone the standard treatment. The patients were randomly divided into two groups: Group 1 (reference, n = 363);Group 2 (test, n = 334). Patients of Group 2 were given the traditional treatment, accompanied with HBOT (isopression for forty minutes at a working pressure of 0.03 MPa). HBOT was applied first through the fifth day following MI. The treatment course included six cycles, once per day. The clinical assessment was focused on clinical outcome: rMI and mortality related to cardiovascular events. HBOT application that accompanied the acute MI with traditional pharmacotherapy has been proved to reduce rMI within five years following inpatient discharge (rMI rate was 14% in the reference group and 5.4% in the test group, χ2 = 13.3, р < 0.05). The combination of HBOT with traditional methods in treating acute MI makes it possible to raise the five-year survival rate from 84.4% up to 95.9%.
文摘Evaluating the outcomes of DOTS program is essential for recognizing and amending system failures before the incidence and proportion of resistant isolates rise. In this study, we seek to evaluate the impact of DOTS strategy on tuberculosis treatment success rate in Dabat, northwest Ethiopia. Medical records of 1305 pulmonary and extrapulmonary tuberculosis patients registered from 2007 to 2012 at two health centers in Dabat district, northwest Ethiopia, were reviewed. Treatment outcomes and forms of tuberculosis were assessed according to WHO guidelines. Descriptive analyses were performed using frequencies and percentages. Treatment success rate was observed in 1146 (87.8%) patients. Out of these, 534 (89.1%) of the males and 612 (86.7%) of the females were successfully treated. It was also true in 338 (87.8%) of the smear-positive pulmonary tuberculosis patients, 473 (85.7%) of the smear-negative pulmonary tuberculosis patients, and 335 (91.0%) of the extrapulmonary tuberculosis patients. In conclusion, treatment success rate in the current study was slightly higher than the WHO international updated target for the period 2011 to 2015. However, this doesn’t mean that there will be no need for further enhancement of supervision and monitoring techniques, strengthening counseling and health education programs, and improving the quality of laboratory diagnostic services.
文摘Comparative investigations were carried out of the effect of heat treatment regimes Jor steel GC-4(40CrMnSiMoVA)on its crack propagating rates,from corrosion fatigue, (da/dN)_(CF),or stress corrosion cracking,(da/dt)_(SCC),in media with various constituents and pH values.Both(da/dN)_(CF) and(da/dt)_(SCC) accelerate with the increase of yield stress of the steel,yet the former is far less than the later.In comparison with media,the (da/dt)_(SCC) in distilled water is slightly greater than that in 3.5% NaCl solution,and the (da/dN)_(CF) in distilled water is far less than that in 3.5% NaCl solution.With the pH value increasing in 3.5% NaCl solution,the(da/dN)_(CF) lowers down and the(da/dt)_(SCC) speeds up.An explanation was also proposed with concept of the cyclic hardening and softening at crack tip,as well as the crack closure and occluded cell effect.
基金supported by Hi-Tech Research and Development Program (863) of China (2006AA11A159)
文摘Surface-treated MmNi3.55Co0.75Mn0.4Al0.3 alloy as negative electrode material of nickel-metal hydride battery was employed to improve the high-rate dischargeability. Surface treatment was realized by dipping and stirring the alloy into a HCl aqueous solution with various concentrations at room temperature. The microstructure of the alloy before and after surface treatment was analyzed by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The electrochemical properties before and after surface treatment were compared, and the alloy treated in 0.025 mol/L HCl solution showed the optimal high-rate dischargeability.
文摘We consider a SIR epidemic model with saturated incidence rate and treatment. We show that if the basic reproduction number, R0 is less than unity and the disease free equilibrium is locally asymptotically stable. Moreover, we show that if R0 > 1, the endemic equilibrium is locally asymptotically stable. In the end, we give some numerical results to compare our model with existing model and to show the effect of the treatment term on the model.
文摘Lab scale biological treatment system was constructed from acrylic and operated using synthetic wastewater to evaluate the nitrification performance using different media. The media used for were Ceramic Ring A (CRA), Ceramic Ring B (CRB), Japanese Filter Mat (JFM), and Filter Wool (FW). Laboratory studies were conducted, in order to evaluate the nitrification performance of different media types, at different synthetic wastewater flow rates, ranging from 0.03 to 0.045 m3/hr. The results from experiments suggest that at higher water flow rates, there was a decrease in nitrification for all media types. Based on the ammonia and nitrite removal rates, FW media gave the optimum nitrification, of up to 0.46 g/m2/day and 0.09 g/m2/day, respectively. Besides, in this study, the surface texture of the media is the main factor that affected the volumetric ammonia and nitrite conversion rates (VTR and VNR). JFM gave the greatest VTR and VNR performance, compared with the other media
基金supported by the Government of Perm Krai,Research Project No.C-26/628 dated 05/04/2021.
文摘A set of techniques for well treatment aimed to enhance oil recovery are considered in the present study.These are based on the application of elastic waves of various types(dilation-wave,vibro-wave,or other acoustically induced effects).In such a context,a new technique is proposed to predict the effectiveness of the elastic-wave well treatment using the rank distribution according to Zipf’s law.It is revealed that,when the results of elastic wave well treatments are analyzed,groups of wells exploiting various geological deposits can differ in terms of their slope coefficients and free members.As the slope coefficient increases,the average increase in the well oil production rate(after the well treatment)becomes larger.An equation is obtained accordingly for estimating the slope coefficient in the Zipf’s equation from the frequency of the elastic wave.The obtained results demonstrate the applicability of the Zipf’s law in the analysis of the technological efficiency of elastic-wave well treatment methods.
基金Supported by Ningbo Science and Technology Plan Project Public Welfare Plan(Municipal Level),No:2019C50099Ningbo Medical Key Supporting Discipline Child Health Science,No:2022-F26。
文摘BACKGROUND Long-term treatment of attention deficit/hyperactivity disorder(ADHD)is associated with adverse events,such as nausea and vomiting,dizziness,and sleep disturbances,and poor maintenance of late ADHD medication compromises treatment outcomes and prolongs the recovery of patients’social functioning.AIM To evaluate the effect of non-pharmacological treatment on the full recovery of social functioning in patients with ADHD.METHODS A total of 90 patients diagnosed with ADHD between May 2019 and August 2020 were included in the study and randomly assigned to either the pharmacological group(methylphenidate hydrochloride and tomoxetine hydrochloride)or the non-pharmacological group(parental training,behavior modification,sensory integration therapy,and sand tray therapy),with 45 cases in each group.Outcome measures included treatment compliance,Swanson,Nolan,and Pelham,Version IV(SNAP-IV)scores,Conners Parent Symptom Questionnaire(PSQ)scores,and Weiss Functional Impairment Rating Scale(WFIRS)scores.RESULTS The non-pharmacological interventions resulted in significantly higher compliance in patients(95.56%)compared with medication(71.11%)(P<0.05).However,no significant differences in SNAP-IV and PSQ scores,in addition to the learning/school,social activities,and adventure activities of the WFIRS scores were observed between the two groups(P>0.05).Patients with non-pharmacological interventions showed higher WFIRS scores for family,daily life skills,and self-concept than those in the pharmacological group(P<0.05).CONCLUSION Non-pharmacological interventions,in contrast to the potential risks of adverse events after longterm medication,improve patient treatment compliance,alleviate patients’behavioral symptoms of attention,impulsivity,and hyperactivity,and improve their cognitive ability,thereby improving family relationships and patient self-evaluation.
文摘Objective:To observe whether the Ear Well infant ear correction system makes any difference in terms of the treatment effect,duration,complication rate,and nursing care requirements in different types of infant auricle deformities.Methods:A total of 93 infant patients with auricular deformity(age:<3 months of age)who were diagnosed and treated in Guangzhou Children and Women’s Medical Center from April 2018 to September 2020 were selected and treated with the Ear Well infant ear correction system.We observed and recorded the effects of the Ear Well infant ear correction system,the treatment duration,the number of rebound cases,and complications that are likely to occur during treatment,and noted the related factors causing complications and the relative requirements for nursing care.Results:The Earwell infant ear correction system could effectively correct infant auricle deformities.Among the 93 cases,90 cases had positive therapeutical outcome and the effective rate was 96.77%.The treatment duration for lop ear and protruding ear was longer than for other auricle deformities;the deformity recoil and the treatment compilation rates were much higher for these 2 deformity types,and the difference was statistically significant(P<0.05).Conclusions:The treatment suggestion for the wearing duration of the Ear Well infant ear correction system for lop ear and protruding ear is a prolonged duration compared with that for other infant auricle deformities.Fur ther,the requirements for nursing care intensity and infant patient’s guardian’s nursing knowledge and skill are obviously increased for these 2 types of auricle deformities.