ACUPUNCTURE COMBINED WITH LANGUAGE TRAINING FOR TREATMENT OF MOTOR APHASIA CAUSED BY ISCHEMIC APOPLEXY

Objective To observe therapeutic effects of acupuncture combined with language training on aphasia induced by ischemic apoplexy and investigate the mechanisms. Methods 60 patients were randomly divided into a treatment group treated by acupuncture associated with language training and a control group treated by simple language training. Tongue-acupuncture was applied as the main therapy, and language training included speech organ training, mouth-shape and voice training, spoken language expression training and practical communication ability training. According to Aphosio Bottery of Chinese （ABC）, language ex- amination evaluation was made, and event related potential （P300） was detected before and after treatment. Results The therapeutic effect in the treatment group was significantly better than that in the control group （P〈O. 05）, and the scores of ABC items including information content, speech fluency, repetition, vocabula- ry denomination, color naming, response denomination, confirmation or negation, acoustic recognition and carrying out instruction in the treatment group were obviously higher than those in the control group （P〈0.05）. After one course of treatment, the latencies of N2 and P3 waves in P300 were significantly short- ened and the amplitude of P3 was significantly elevated in the treatment group, compared with those in the control group （P〈0.05）. Conclusion Acupuncture combined with language training provided remarkable therapeutic effects in treating cerebral infarction-induced motor aphasia, and it was better than simple lan- guage training. The results of enhancing of the ABC scores including information content, speech fluency, repetition, vocabulary denomination, color naming, response denomination, confirmation or negation, acous- tic recognition and carrying out instruction, and shortening of the latencies of N2 and P3 waves in P300 and ele- vation of P3 amplitude may be taken as the indices for evaluating and anticipating clinical therapeutic effects of the therapy for treating the disease, which may also be some of the mechanisms.

CLINICAL OBSERVATION ON TREATMENT OF CEREBRAL APOPLEXY-INDUCED APHASIA BY ACUPUNCTURE

Acupuncture therapy was adopted in the present study to treat aphasia caused by cerebral apoplexy. Among the 24 patients in treatment group, 13 cases were cured, 6 were markedly improved, 4 improved and 1 ineffective. The total effective rate of this group was 95. 8%. Of the patients in the control group, 6 cases were cured, 5 markedly improved, 10 improved and 3 ineffective.The overall curative rate was 87. 5%. The therapeutic results of these two groups were statistically significantly different (P<0.05), the result of the treatment group superior to that of the control group. The obtained results indicate that the acupuncture therapy is an effective way for this illness.

Personalized Management of Chronic Myeloid Leukemia Presenting with Ovarian Apoplexy and Review of Health Emergency Cases

Introduction: Chronic myeloid leukemia (CML) may significantly affect quality of life and life expectancy in the accelerated and acute phases, especially if presented with health emergencies. Objective: The purpose of the study was the evaluation of the personalized management milestones in CML cases presented with ovarian apoplexy and the analysis of the international experience on health emergencies in this leukemia. Materials and Methods: An original, case-report study was performed. The diagnosis was confirmed by cytological, cytogenetic and molecular examinations of the peripheral blood and bone marrow at the comprehensive research cancer center— Institute of Oncology from Moldova. The real-time PCR was performed for quantitative detection of BCR-ABL gene p210 and p190 transcripts. The ECOG Scale and complete hematologic response (CR) estimated the short-term results. The ECOG performance status served as a measure of functional status. Its scores range from 0 to 5 and correlate with the level of patient functioning. CR is the disappearance of all detectable clinical and hematological signs of malignant neoplasm in response to treatment. CR span was assessed in months. The overall and relapse-free survivals asserted the long-term results of treatment, and were evaluated in months as a case. Results: CML may be manifested by life-threatening conditions, including infections and thrombotic events, splenic infarcts and ruptures, bleedings, etc. CML with the uncommon onset under the form of the ovarian apoplexy is described. The hematological CR was obtained under the treatment with imatinib mesylate. The molecular CR and the long-lasting overall survival (197.5 months) were achieved after the treatment with nilotinib. Under the treatment with tyrosine kinase inhibitors, the patient did not experience the disease burden and side effects, and resumed her work, with a good life quality (ECOG score is 0). Discussion: CML may be manifested by life-threatening health emergencies, especially thrombotic events, splenic infarcts and ruptures, bleedings, etc. The CML patients with high leukocyte and platelet counts may experience also different symptoms of hyperviscosity: tinnitus, priapism, stupor, visual abnormalities and cerebrovascular accidents. However, the management of CML with the life-threatening conditions, especially in the accelerated and acute phases, should be realized with participation of the multidisciplinary teams. Conclusions: The ovarian apoplexy may serve as a presenting feature of CML in young females with a highly elevated leukocyte count. The reported CML case underwent successful personalized management with 2 generations of tyrosine kinase inhibitors, even if designated with Socal intermediate-risk score and complicated by a health emergency.

Photobiomodulation with Super-Pulsed Laser Shows Efficacy for Stroke and Aphasia: Case Studies

Background: Brain disorders have become more and more common today, due to both the aging population and the ever-expanding sports community. However, a new therapeutic technology called photobiomodulation (PBM) is giving hope to thousands of individuals in need. Traumatic brain injury (TBI), dementia, post traumatic stress (PTSD) and attention deficit (ADD) disorders are in many cases quickly and safely improved by PBM. PBM employs red or near-infrared (NIR) light (600 - 1100 nm) to stimulate healing, protect tissue from dying, increase mitochondrial function, improve blood flow, and tissue oxygenation. PBM can also act to reduce edema, increase antioxidants, decrease inflammation, protect against apoptosis, and modulate the microglial activation state. All these effects can occur when light is delivered to the head, and can be beneficial in both acute and chronic brain conditions. Methods: In this case series, we used a high power, FDA-approved superpulsed laser system applied to the head to treat four chronic stroke patients. Patients received as few as three 6 - 9 minute treatments over a one-week period. The follow up time varied, but in one case was two years. Results: Patients showed significant improvement in their speech and verbal skills. Improvements were also noticed in walking ability, limb movement, less numbness, and better vision. Conclusion: The use of PBM in stroke rehabilitation deserves to be tested in controlled clinical trials, because this common condition has no approved pharmaceutical treatment at present.

Pituitary apoplexy secondary to dengue fever-induced-thrombocytopenia:A case report and review of literature

Rationale:Pituitary apoplexy(PA)is a rare endocrine emergency that requires prompt diagnosis and management.Dengue fever-induced-thrombocytopenia may rarely predispose to PA.Patient’s Concern:A 58-year-old male patient having known pituitary macroadenoma presented to the emergency department with fever,a sudden onset severe headache,and altered sensorium.Diagnosis:Pituitary apoplexy caused by dengue fever-induced-thrombocytopenia.Interventions:Conservative management with fluids,mannitol,dexamethasone and symptomatic treatment.Outcomes:The patient responded well to the treatment and was discharged uneventfully.Lessons:Although dengue hemorrhagic fever is a rare cause of pituitary apoplexy,it should be considered if a patient presents with headache and altered sensorium,and prompt initiation of treatment is crucial to prevent fatality and neuro-ophthalmic deficits.

Effect of scalp acupuncture combined with language rehabilitation training in treating post-stroke motor aphasia:A systematic review and meta-analysis

Objective:To evaluate the efficacy of scalp acupuncture combined with language rehabilitation training in the treatment of motor aphasia.Methods:CNKI,VIP,Wan Fang Database,MEDLINE,Embase,Web of Science and Cochrane Library were searched for published researches up to March,2021.Randomized controlled trials RCTs that focused on scalp acupuncture combined with language rehabilitation training in the treatment of motor aphasia were included.We managed the data analysis with RevMan 5.3 software.Results:A total of 16 RCTs with 1323 patients were involved.The results of meta-analysis showed that:①The effective rate of scalp acupuncture combined with language rehabilitation training in the treatment of motor aphasia after stroke was significantly better than that of simple language rehabilitation training[OR=3.94,95%CI(2.73,5.68),P<0.00001];②In the evaluation of language function,compared with the language rehabilitation training,the scalp acupuncture combined with language rehabilitation training can significantly improve the reading ability of the patients with motor aphasia after stroke[MD=7.22,95%CI(3.55,10.89),P=0.0001],writing ability[MD=6.51,95%CI(3.61,9.41),P<0.0001],expressive ability[MD=4.13,95%CI(2.37,5.89),P<0.0001],retelling ability[MD=5.00,95%CI(2.38,7.63),P=0.0002],listening comprehension ability[MD=5.36,95%CI(3.12,7.61),P<0.00001]and naming ability[MD=5.60,95%CI(4.20,7.00),P<0.00001];③Compared with simple language rehabilitation training,scalp acupuncture combined with language rehabilitation can significantly improve the daily life language communication ability of patients with motor aphasia,and the difference was statistically significant[MD=30.01,95%CI(11.30,48.72),P=0.002].Conclusion:Scalp acupuncture combined with language rehabilitation training has a significant effect on motor aphasia.However,due to the small sample size,more RCTs are needed to confirm that.

Study of Native Culture Aphasia and Compensation Strategies in English Education

English teaching in China has attached too much importance to the input of the target language culture,while neglecting our native culture.As a result,students cannot express Chinese culture in English,completely separating Chinese culture from English learning,leading to the serious native culture aphasia.This paper not only analyzes the reasons for this phenomenon from the aspects of curriculum setting,learning motivation,and teachers’quality,but also explains the necessity of integrating Chinese native culture in English teaching.On this basis,effective solutions are put forward from the perspective of classroom teaching,textbook compilation,curriculum arrangement,and so on.

失语症研究的语言学转向

失语症研究的发展经历了由医学主导到心理学主导,再到语言学主导,再到目前多学科交叉的变化过程。目前,在世界范围内从语言学视角开展失语症研究的热潮正在形成,主要包括失语症言语特征、失语症患者语言能力评估以及失语症的康复训练。本文从这三个视角介绍中西方失语症研究的概况,论述失语症研究需要开展的工作,尤其是我国失语症研究需要开展的工作,为我国语言学学者从事失语症研究指明方向。

脑卒中康复期患者社会疏离、病耻感及生存质量的相关性研究

目的对脑卒中康复期患者社会疏离、病耻感及生存质量进行现状调查、分析其相关性,并探讨生存质量的影响因素。方法选取2022年1月至2023年6月就诊于本院的110例脑卒中患者为研究对象,采用一般资料问卷、一般疏离感量表、社会影响量表、健康调查简表对入组脑卒中患者进行问卷调查。结果共有110例脑卒中患者进入本研究,其中,缺血性卒中82例,出血性卒中28例,年龄48~79岁,平均(54.53±7.45)岁,男性69例,占比62.73%,女性41例,占比37.27%。量表评估结果显示:社会疏离得分(48.58±5.46)分、病耻感得分(70.64±6.45)分、生存质量得分(50.26±6.42)分。脑卒中康复期患者社会疏离得分与病耻感得分间呈现正相关关系(r=0.425,P=0.013);社会疏离得分与生存质量得分间呈负相关关系(r=-0.326,P=0.009);病耻感得分与生存质量得分间负相关关系(r=-0.315,P=0.022)。影响因素分析结果显示:月收入、受教育程度、社会疏离得分及病耻感得分是脑卒中康复期患者生存质量得分的影响因素(P<0.05)。结论脑卒中康复期患者社会疏离水平较高、病耻感水平一般、生存质量水平一般。提示临床护理人员应根据患者具体疾病情况,不仅需要密切关注患者疾病及康复情况,也需要最大限度的降低患者出现的社会疏离和病耻感水平,改善患者可能出现的社会性衰弱,对提高脑卒中康复期患者的生存质量有积极意义。

左侧脑卒中后上肢运动功能与失语症的相关性分析

目的:观察左侧脑卒中患者上肢运动功能障碍和失语症之间的相关程度。方法:回顾性收集住院接受语言功能评估的438例患者资料,包括一般资料、汉语标准失语症检查表(CRRCAE)总分及分项得分、Fugl-Meyer运动功能评分上肢部分评分(FMA-UE评分),对以上数据进行相关性分析。按照病程将患者分为3组,病程≤30d的患者108例,30d<病程≤90d的患者219例,病程>90d的患者111例。结果:CRRCAE总分与FMA-UE得分之间有相关性(r=0.55~0.65,P<0.01);3组的CRRCAE总分、各分项得分,均与FMA-UE得分之间有相关性(P<0.01),CRRCAE总分与FMA-UE得分之间存在中度正相关关系(r=0.55~0.65,P<0.01),病程>90d的患者有最强的相关性(r=0.65,P<0.01)。将损伤部位作为控制变量,对以上数据进行了偏相关分析,3组的CRRCAE总分、各分项得分,与FMA-UE得分之间仍然存在轻中度的正相关关系(P<0.01)。结论:左侧脑卒中患者失语与上肢运动功能之间存在正相关关系,临床中可考虑设计一些运动相关的失语症训练方法,来改善语言功能。

新安医家吴楚辨治中风特色探析

整理分析《宝命真诠》《吴氏医验录》及相关文献,探讨吴楚治疗中风病的特色。吴楚主张将中风分为真中风和类中风两大类,认为内虚风中是真中风的基本病机特点,主张从脏腑、血脉、闭脱三方面进行辨别,并以汗、下、养血顺气三法进行论治。对于类中风的治疗,吴楚认为其基本病机特点为元阳虚衰、痰火内动,主张采用八因素法辨别,重视采用攻痰祛积,甘温补虚法治疗。

卒中后失语工作记忆的事件相关电位及时频特征

目的 探索卒中后失语(PSA)工作记忆的任务态脑电特征。方法 2020年9月至2021年2月,于北京中医药大学东直门医院招募PSA患者(PSA组)和健康受试者(HC组)各8例,采集脑电图和记忆量表数据,通过工作记忆任务态的脑电数据分析时域事件相关电位(ERP)和时频的脑电频段指标特点,与记忆量表中的各项目进行相关性分析。结果 最终纳入10例,每组5例。ERP分析发现前额区诱发N1和P2成分,顶枕区诱发P300成分。与HC组相比,PSA组在出现条件下,中央前额区N1和P2激活增强,右侧顶枕区P300活动降低(|t|> 2.193, P <0.05)。与HC组相比,PSA组在未出现条件下右侧前额区、中央顶枕区θ频段能量降低,左侧顶枕区α1频段能量降低,左侧中央区γ频段能量增加(t> 2.398, P <0.05)。相关性分析显示,γ频段的能量与听觉词语学习测验中的即刻回忆(r=0.914, P=0.030)、正确再认(r=0.931, P=0.022)和数字广度测验中的倒背(r=0.924, P=0.025)、顺背(r=0.889, P=0.044)呈强正相关。结论 视觉工作记忆任务可调动PSA患者记忆相关脑区代偿活动,可作为PSA工作记忆相关研究的评价客观指征。语言损伤与工作记忆之间存在密切联系。

热敏灸治疗脑卒中后痉挛性偏瘫患者的热敏化穴位分布情况及疗效观察

目的探查热敏灸治疗脑卒中后痉挛性偏瘫患者热敏化穴位的分布情况,观察热敏灸治疗痉挛性偏瘫患者的临床疗效。方法将70例脑卒中后痉挛性偏瘫患者随机分为对照组和热敏灸组,每组35例;对照组采用常规康复治疗和针刺治疗,热敏灸组在对照组治疗基础上采用热敏灸治疗;观察热敏灸组患者热敏化穴位分布情况,比较两组患者治疗前后美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分和改良Rankin量表(modified Rankin scale,MRS)评分、徒手肌力检查(manual muscle testing,MMT)评分、Fugl-Meyer评估(Fugl-Meyer assessment,FMA)量表评分、Wolf运动功能测试(Wolf motor function test,WMFT)量表评分、日常生活活动能力(activity of daily living,ADL)量表评分、世界卫生组织生活质量简表(World Health Organization quality of life brief,WHOQOL-BREF)评分以及临床疗效。结果共有35例患者出现热敏化穴位现象,共出现119个热敏化穴位;热敏化穴位中出现频率最高的5个穴位依次为足三里、曲池、悬钟、外关和阳陵泉。热敏灸组NIHSS评分、MRS评分均显著低于对照组(P<0.05),MMT评分、FMA量表评分、WMFT量表评分、ADL量表评分、WHOQOL-BREF各维度评分均显著高于对照组(P<0.05)。热敏灸组临床疗效显著优于对照组(P<0.05)。结论热敏灸联合常规针刺和康复治疗脑卒中后痉挛性偏瘫,能够显著改善患者肢体功能障碍,提高生活质量,疗效确切;应用热敏灸治疗该病时可优先选择足三里、曲池、悬钟、外关、阳陵泉穴进行治疗。

重复经颅磁刺激联合刮痧疗法对中风后失眠患者的干预效果

目的:分析中风后失眠患者行重复经颅磁刺激联合刮痧疗法干预的应用价值。方法:择取2022年2月—2023年8月江西中医药大学附属医院收治的中风后失眠患者60例,随机分为对照组和观察组,各30例。对照组实施重复经颅磁刺激,观察组在对照组基础上加用刮痧疗法。比较两组临床疗效、睡眠质量[匹兹堡睡眠质量指数(PSQI)]、生活质量[脑卒中专用生活质量量表(SS-QOL)]。结果:观察组总有效率高于对照组(P<0.05);干预4周后,两组PSQI评分均明显降低,且观察组低于对照组(P<0.05);干预4周后,两组SS-QOL评分均较干预前升高,且观察组高于对照组(P<0.05)。结论:中风后失眠患者行重复经颅磁刺激联合刮痧疗法效果明显,可改善患者睡眠障碍及生活质量。

叶酸干预对MTHFR基因型和脑卒中发生风险的相关性研究

目的:探讨叶酸干预对亚甲基四氢叶酸还原酶(MTHFR)基因型和脑卒中发生风险的相关性研究。方法:选取2022年1月至2022年12月于佳木斯大学附属第一医院就诊的100例脑卒中患者为受试者,其中包含缺血性脑卒中、H型高血压并发缺血性脑卒中等不同类型的患者,按照治疗方法不同将其分为两组。对照组受试者给予低剂量叶酸进行治疗;研究组受试者给予高剂量叶酸进行治疗。对两组受试者MTHFR基因多态性频率、MMSE评分、叶酸干预后Hcy的指标水平、脑卒中多因素回归分析以及叶酸干预是否增加脑卒中发生风险的相关性分析等指标进行观察。结果:研究组受试者MTHFR的C677T位点基因型以CT和TT为主,其中TT型和CT型基因频率高于对照组,CC型基因频率低于对照组,差异有统计学意义(P<0.05);两组受试者基线差异无统计学意义(P>0.05),研究组在第8周时MMSE评分为(28.50±0.69)分高于对照组(t=13.016,P<0.001);两组受试者干预前无统计学意义(P>0.05)。受试者经治疗后,研究组受试者Hcy水平为(11.67±1.46)μmoI/L高于对照组(t=15.363,P<0.001)将研究组=1,对照组=0,单因素分析差异显著的因素作为协变量进行逻辑回归分析,TT、CC、Hcy均是影响脑卒中的主要危险因素。Log(P)=TT×3.365+CC×5.365+Hcy×7.520-23.961;Pearson分析结果显示,脑卒中受试者疾病发生风险与叶酸干预总分呈负相关(r=-3.465,P=0.467),脑卒中受试者叶酸干预越高,即脑卒中发生风险越低。结论:Hcy是影响脑卒中患者脑卒中发生的一项重要的影响因素,对于脑卒中患者可以在适当的范围之内给予叶酸,降低Hcy水平,减少脑卒中的发生。

改善高职公共英语课程“中国文化失语”现象的策略与路径

在讲好中国故事、构建中国叙事体系的时代背景下,高职公共英语课程教学中长久存在的“中国文化失语”现象一直未见明显改观,且弊端尤为凸显。基于母语文化和目的语文化严重失衡的现状,从价值引领、学科素养和文化自信三个方面提出将中国传统文化融入英语课程教学的策略,并基于实践经验,从教学主体、教学体系、教学内容和教学评价四个维度提炼了有效改善“中国文化失语”现象的实施路径。

通络扶正汤对脑卒中后遗症患者血清Wnt3a、Wnt5a表达量及神经功能影响分析

【目的】分析通络扶正汤(由胆南星、法半夏、桃仁、天麻、全蝎、红花、地龙等中药组成)对脑卒中后遗症患者神经功能及血清分泌型糖蛋白(Wnt)3a、Wnt5a表达量的影响。【方法】采用回顾性研究方法,根据治疗方案的不同将146例脑卒中后遗症风痰瘀阻证患者分为观察组和对照组,每组各73例。对照组给予常规西药及康复治疗,观察组在对照组的基础上给予通络扶正汤治疗,疗程为3周。观察2组患者治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、Berg平衡量表(BBS)评分、Fugl-Meyer量表(FMA)评分、Holden步行功能分级(FAC)、躯干屈伸肌群表面肌电均方根值(RMS)及血清Wnt3a、Wnt5a表达量的变化情况,并比较2组患者的临床疗效和不良反应发生率。【结果】(1)治疗3周后,观察组的总有效率为95.89%(70/73),对照组为79.45%(58/73),组间比较,观察组的疗效明显优于对照组(P<0.01)。(2)治疗后,2组患者的NIHSS评分均较治疗前明显降低(P<0.05),BBS、FMA评分均较治疗前明显升高(P<0.05),且观察组对NIHSS评分的降低幅度及对BBS、FMA评分的升高幅度均明显优于对照组(P<0.01)。(3)治疗后,2组患者的FAC分级均较治疗前改善(P<0.05),且观察组对FAC分级的改善作用明显优于对照组(P<0.05)。(4)治疗后,2组患者的竖脊肌、腹直肌表面肌电RMS值均较治疗前明显升高(P<0.05),且观察组对竖脊肌、腹直肌表面肌电RMS值的升高幅度均明显优于对照组(P<0.01)。(5)治疗后,2组患者的血清Wnt3a、Wnt5a表达量均较治疗前明显升高(P<0.05),且观察组对血清Wnt3a、Wnt5a表达量的升高幅度均明显优于对照组(P<0.01)。(6)观察组的不良反应发生率为4.11%(3/73),对照组为6.85%(5/73),组间比较,差异无统计学意义(P>0.05)。【结论】通络扶正汤可有效减轻脑卒中后遗症患者神经功能受损程度及运动障碍,提高平衡能力及治疗效果,增强躯干屈伸肌群肌力,上调血清Wnt3a、Wnt5a表达量,且不良反应发生率低,具有较高的安全性。

额外椅-立运动对老年科卒中重度偏瘫患者心肺健康的影响

目的:探讨额外椅-立运动对老年科卒中重度偏瘫患者心肺健康的影响。方法:选取老年科71例卒中患者分为观察组36例、对照组35例,两组均常规治疗与训练,观察组额外开展椅-立运动。比较两组干预前后用力肺活量(FVC)、1s用力呼气量(FEV1)、左室射血分数(LVEF)、峰值摄氧量(VO2peak)、峰值分钟通气量(VE peak)、6 min步行试验(6MWT)、屈伸膝关节总功率(TW)、峰力矩(PT)、相对峰力矩(PT/W)。结果:观察组干预后FVC、FEV1、LVEF、VO_(2peak)、VE_(peak)、TW、PT、PT/W、6MWT水平高于对照组(P<0.05)。结论:额外椅-立运动可改善老年科重度偏瘫患者的心肺功能、肌肉力量。

互动式头针对脑卒中恢复期患者平衡功能障碍的临床研究

目的探讨互动式头针对脑卒中恢复期患者平衡功能障碍的临床疗效。方法采用随机对照研究方法,收集2020年9月—2021年10月期间在该院就诊的97例患者,互动式头针组采用头针同时+平衡功能康复训练,传统头针组采用头针后+平衡功能康复训练。分析治疗前后的NIHSS、Berg平衡、Barthel评分的变化。结果治疗4周后,互动式头针组、传统头针组的NIHSS、Berg平衡、Barthel评分均较治疗前改善(均P<0.05),且互动式头针组改善NIHSS、Berg平衡、Barthel评分幅度优于传统头针组(均P<0.05)。结论互动式头针治疗脑卒中后平衡功能障碍较头针后平衡功能训练更有利于患者平衡功能的恢复及日常生活能力的提高,值得临床应用。

靳三针联合康复训练在脑卒中后假性球麻痹吞咽功能障碍中的应用价值研究

目的:探究靳三针联合康复训练在脑卒中(CA)后假性球麻痹(PBP)吞咽功能障碍中的应用价值。方法:将符合纳入标准的92例CA后PBP吞咽功能障碍患者进行研究,按照简单随机法分为观察组和对照组各46例,对照组给予康复训练治疗,观察组行康复训练及靳三针治疗,比较两组临床疗效、吞咽功能、舌喉吞咽能力[改良曼恩吞咽能力评估量表(MMASA)]、血清神经性因子水平及不良反应。结果:观察组总有效率显著高于对照组,差异有统计学意义(P<0.05);治疗两周后,两组洼田饮水试验分级及评分均显著降低,差异有统计学意义(P<0.05),MMASA各维度评分、血清NGF、BDNF及IGF-1水平均显著升高,差异有统计学意义(P<0.05),NSE水平显著降低(P<0.05),且组间比较差异有统计学意义(P<0.05);治疗期间,两组患者均无明显不良反应。结论:CA后PBP吞咽功能障碍患者采用靳三针、康复训练联合治疗临床疗效可观,患者舌喉吞咽能力、神经功能均明显改善。