Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related pro...Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.展开更多
Medical Geology,the emerging discipline that focuses on the health impacts of geologic materials and geologic processes,has its roots in Guizhou Province,China.In the 1980 s Prof.Zheng Baoshan and his students recogni...Medical Geology,the emerging discipline that focuses on the health impacts of geologic materials and geologic processes,has its roots in Guizhou Province,China.In the 1980 s Prof.Zheng Baoshan and his students recognized that a large number of people in Guizhou Province had clinical symptoms of arsenic poisoning,fluorine exposure,selenosis,and other diseases caused by exposure to potentially toxic trace elements or due to deficiency of essential elements.Their publications and invitations to scientists to visit the Province ultimately resulted in increased attention to the health impacts of the natural environment and the formation of scientific societies,the publication of at least a dozen books,and thousands of technical articles on what is now called Medical Geology.展开更多
This study aimed to describe the distribution of water-arsenic(As)valence states and its relationship to areas with endemic arsenism in the Datong basin.Drinking water samples of patients with endemic arsenism and a c...This study aimed to describe the distribution of water-arsenic(As)valence states and its relationship to areas with endemic arsenism in the Datong basin.Drinking water samples of patients with endemic arsenism and a control group were examined using hydride generation atomic fluorescence spectrometry(HG-AFS).We analyzed the data using SPSS10.0 for Windows.The As(III)/As ratio was 52.1%in the water sample,exceeding the national standard of 0.05 mg/L.The As(III)/As ratio significantly varied among the different stages in the disease-state groups,and with the control group(χ^(2)=22.4,P<0.01).The As(III)/As(V)ratio significantly varied in the four groups(χ^(2)=26.19,P<0.01),with a tendency to increase along with the seriousness of the disease state.The most common type of drinking water arsenic valence state was As(III)in the endemic diseaseareas.Endemic arsenism was positively correlated with As(III).This led us to conclude that the fraction of each water-arsenic valence state should be studied when determining the arsenic content of drinking water.展开更多
基金supported by the Guangxi Bureau of Traditional Chinese Medicine,No.[2009]73the Department of Science and Technology,Guangxi Zhuang Autonomous Region,No.0640203
文摘Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.
文摘Medical Geology,the emerging discipline that focuses on the health impacts of geologic materials and geologic processes,has its roots in Guizhou Province,China.In the 1980 s Prof.Zheng Baoshan and his students recognized that a large number of people in Guizhou Province had clinical symptoms of arsenic poisoning,fluorine exposure,selenosis,and other diseases caused by exposure to potentially toxic trace elements or due to deficiency of essential elements.Their publications and invitations to scientists to visit the Province ultimately resulted in increased attention to the health impacts of the natural environment and the formation of scientific societies,the publication of at least a dozen books,and thousands of technical articles on what is now called Medical Geology.
文摘This study aimed to describe the distribution of water-arsenic(As)valence states and its relationship to areas with endemic arsenism in the Datong basin.Drinking water samples of patients with endemic arsenism and a control group were examined using hydride generation atomic fluorescence spectrometry(HG-AFS).We analyzed the data using SPSS10.0 for Windows.The As(III)/As ratio was 52.1%in the water sample,exceeding the national standard of 0.05 mg/L.The As(III)/As ratio significantly varied among the different stages in the disease-state groups,and with the control group(χ^(2)=22.4,P<0.01).The As(III)/As(V)ratio significantly varied in the four groups(χ^(2)=26.19,P<0.01),with a tendency to increase along with the seriousness of the disease state.The most common type of drinking water arsenic valence state was As(III)in the endemic diseaseareas.Endemic arsenism was positively correlated with As(III).This led us to conclude that the fraction of each water-arsenic valence state should be studied when determining the arsenic content of drinking water.
