The implantable artificial hair was prepared by grafting collagen on the surface of poly( ethylene terephthalate)( PET) to improve its biocompatibility. Acrylic acid( AAc) was used to modify the surface properties of ...The implantable artificial hair was prepared by grafting collagen on the surface of poly( ethylene terephthalate)( PET) to improve its biocompatibility. Acrylic acid( AAc) was used to modify the surface properties of PET firstly,and then collagen was grafted on the PET-AAc surface. The concentration of collagen solution was discussed to graft more collagen on PET surface. Composites were well characterized by scanning electron microscopy( SEM),Fourier transform infrared spectroscopy( FTIR) and X-ray photoelectron spectroscopy( XPS). SEM indicated that collagen with about 3. 07μm thickness was coated on PET surface when the concentration of collagen solution was 1. 0 mg/m L. FTIR and XPS showed AAc and collagen were both on the surface of PET monofilaments. The optimized concentration of collagen solution was 1. 0 mg/m L,resulting in the most grafting density of 3. 46 μg/cm2. It can be concluded that a large amount of collagen is coated on PET surface.展开更多
Nucleus Pulposus(NP)Replacement is a developing surgical methodology for the treatment of pathology related to degeneration of intervertebral discs(IVDs).This article provides necessary context regarding the patholo-g...Nucleus Pulposus(NP)Replacement is a developing surgical methodology for the treatment of pathology related to degeneration of intervertebral discs(IVDs).This article provides necessary context regarding the patholo-gies treated with this technology,the biomechanical structure and function of the IVD,and the procedures this technology aims to replace.Primarily,it provides an overview and discussion of commercial and experimental preformed and in situ curing prosthesis designs reported in the scientific literature and summarizes the results of biomechanical and clinical studies evaluating their efficacy.Contextual and updated information on the most recent research into NP replacement with novel hydrogel and tissue engineering(TE)strategies is described.Replacement of the NP allows for potential improvement in the treatment of degenerative spinal pathologies through minimally invasive surgical techniques.展开更多
基金Beijing Municipal Commission of Science and Technology Plan Projects,China(No.KYTG02170206/016)Open Project of Beijing Key Laboratory of Clothing Materials R&D and Assessment,China(No.KYTG02170205)
文摘The implantable artificial hair was prepared by grafting collagen on the surface of poly( ethylene terephthalate)( PET) to improve its biocompatibility. Acrylic acid( AAc) was used to modify the surface properties of PET firstly,and then collagen was grafted on the PET-AAc surface. The concentration of collagen solution was discussed to graft more collagen on PET surface. Composites were well characterized by scanning electron microscopy( SEM),Fourier transform infrared spectroscopy( FTIR) and X-ray photoelectron spectroscopy( XPS). SEM indicated that collagen with about 3. 07μm thickness was coated on PET surface when the concentration of collagen solution was 1. 0 mg/m L. FTIR and XPS showed AAc and collagen were both on the surface of PET monofilaments. The optimized concentration of collagen solution was 1. 0 mg/m L,resulting in the most grafting density of 3. 46 μg/cm2. It can be concluded that a large amount of collagen is coated on PET surface.
文摘Nucleus Pulposus(NP)Replacement is a developing surgical methodology for the treatment of pathology related to degeneration of intervertebral discs(IVDs).This article provides necessary context regarding the patholo-gies treated with this technology,the biomechanical structure and function of the IVD,and the procedures this technology aims to replace.Primarily,it provides an overview and discussion of commercial and experimental preformed and in situ curing prosthesis designs reported in the scientific literature and summarizes the results of biomechanical and clinical studies evaluating their efficacy.Contextual and updated information on the most recent research into NP replacement with novel hydrogel and tissue engineering(TE)strategies is described.Replacement of the NP allows for potential improvement in the treatment of degenerative spinal pathologies through minimally invasive surgical techniques.
