An efficient method for the synthesis of functionalized chroman-4-ones induced by visible light via the radical cyclization reaction of sulfinic acids and o-(allyloxy)arylaldehydes at room temperature was described.Th...An efficient method for the synthesis of functionalized chroman-4-ones induced by visible light via the radical cyclization reaction of sulfinic acids and o-(allyloxy)arylaldehydes at room temperature was described.The corresponding products were isolated with moderate to good yields.Radical mechanism was proposed fo r this trans formation.Anti-microbial activity of some desired compounds we re screened.展开更多
In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring-closure product quinoline derivatives b can be also obtained in 26%—50% yields...In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring-closure product quinoline derivatives b can be also obtained in 26%—50% yields. The substituent effects were also examined and a possible reaction mechanism was proposed for the formation of b. The X-ray crystal structure of 1b confirms the structure of the ring-closure product.展开更多
基金the National Natural Science Foundation of China(No.21772107)Shandong Province Key Research and Development Plan(No.2019GSF108017)。
文摘An efficient method for the synthesis of functionalized chroman-4-ones induced by visible light via the radical cyclization reaction of sulfinic acids and o-(allyloxy)arylaldehydes at room temperature was described.The corresponding products were isolated with moderate to good yields.Radical mechanism was proposed fo r this trans formation.Anti-microbial activity of some desired compounds we re screened.
基金Project supported by the National Natural Science Foundation of China (No. 60171008) and the Ministry of Education China.
文摘In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring-closure product quinoline derivatives b can be also obtained in 26%—50% yields. The substituent effects were also examined and a possible reaction mechanism was proposed for the formation of b. The X-ray crystal structure of 1b confirms the structure of the ring-closure product.
