:应用 Gd-DTPA 雾化颗粒作为对比剂进行犬肺部 M R 成像,探讨其在肺实质 M R 成像中的作用。方法:选择北方健康家犬 条,分别吸入雾化的 6 NaCl和Gd-DTPA 后行 M R扫描...:应用 Gd-DTPA 雾化颗粒作为对比剂进行犬肺部 M R 成像,探讨其在肺实质 M R 成像中的作用。方法:选择北方健康家犬 条,分别吸入雾化的 6 NaCl和Gd-DTPA 后行 M R扫描,通过测量肺实质信号强度( )增加幅度,了解其在肺内的分布。 SI结果:吸入生理盐水蒸汽后肺实质信号强度增加了 11.5% ~25.8%,平均 15.8%,与吸入空气时的信号强度相比无统计学差异 (t=2.798,P>0.05);吸入 Gd-DTPA 雾化颗粒后肺实质信号强度明显增加,增强幅度 42.7~76.8%,平均 59.2%,与吸入空气时的信号强度相比有统计学差异 t=4.660,P <0.05) ( 。结论:雾化的 Gd-DTPA 可以作为一种有效的肺部 M RI增强对比剂,应用雾化 Gd-DTPA 来获得大型实验动物的有关肺通气信息是可行的。展开更多
The clinical study of solute removal index (SRI) was performed in 20 stable maintenance hemodialysis patients in order to find a proper hemodialydsis dosage and improve the life quality of the patients.Plasma BUN leve...The clinical study of solute removal index (SRI) was performed in 20 stable maintenance hemodialysis patients in order to find a proper hemodialydsis dosage and improve the life quality of the patients.Plasma BUN levels were tested pre-hemodialysis and 0, 1 hr post-hemodialysis. Urea generation rate (G)、protein catabolic rate(PCR)、solute removal amount(R)、SRI were calculated by double pools urea kinetic model . The result showed that urea rebound rate was 18.5±3.35 % 1 hr after hemodialysis,R was 13.82±5.48 g, G was 4.85±1.39 g, PCR was 0.94±0.29 g/kg.d, SRI was 71.33±6.8% respectively, which indicated that SRI was a better index to quantitate the adequacy of hemodialysis.展开更多
文摘The clinical study of solute removal index (SRI) was performed in 20 stable maintenance hemodialysis patients in order to find a proper hemodialydsis dosage and improve the life quality of the patients.Plasma BUN levels were tested pre-hemodialysis and 0, 1 hr post-hemodialysis. Urea generation rate (G)、protein catabolic rate(PCR)、solute removal amount(R)、SRI were calculated by double pools urea kinetic model . The result showed that urea rebound rate was 18.5±3.35 % 1 hr after hemodialysis,R was 13.82±5.48 g, G was 4.85±1.39 g, PCR was 0.94±0.29 g/kg.d, SRI was 71.33±6.8% respectively, which indicated that SRI was a better index to quantitate the adequacy of hemodialysis.