In this paper, we describe a patient with a rather severe form of aspirin-induced asthma (AIA) and allergic bronchopulmonary aspergillosis (ABPA). The patient is a man born in 1948, who first presented with rhinor...In this paper, we describe a patient with a rather severe form of aspirin-induced asthma (AIA) and allergic bronchopulmonary aspergillosis (ABPA). The patient is a man born in 1948, who first presented with rhinorrhea, nasal congestion and chronic urticaria, and had an episode of asthma after ingestion of non-steroidal anti-inflammatory drugs (NSAIDs) for the further eight years. He was diagnosed as AIA and the symptoms decreased in frequency when avoiding NSAIDs. At the age of 45, he presented with unusual symptoms, such as malaise, fever, and coughing. The diagnosis of ABPA was made based on his clinical features, such as the symptoms of asthma, typical pulmonary imaging, positive skin test, and high levels of the total IgE (T-IgE) and sIgE. Itraconazole accompanied with oral prednisone prevented pulmonary disease from developing.展开更多
文摘In this paper, we describe a patient with a rather severe form of aspirin-induced asthma (AIA) and allergic bronchopulmonary aspergillosis (ABPA). The patient is a man born in 1948, who first presented with rhinorrhea, nasal congestion and chronic urticaria, and had an episode of asthma after ingestion of non-steroidal anti-inflammatory drugs (NSAIDs) for the further eight years. He was diagnosed as AIA and the symptoms decreased in frequency when avoiding NSAIDs. At the age of 45, he presented with unusual symptoms, such as malaise, fever, and coughing. The diagnosis of ABPA was made based on his clinical features, such as the symptoms of asthma, typical pulmonary imaging, positive skin test, and high levels of the total IgE (T-IgE) and sIgE. Itraconazole accompanied with oral prednisone prevented pulmonary disease from developing.