Antioxidant and lipoxygenase inhibitory properties of a novel flavonoid from Pistacia chinensis Bunge and its molecular docking analysis

Background:Pistacia chinensis Bunge has been traditionally used to manage various conditions,including asthma,pain,inflammation,hepatoprotection,and diabetes.The study was conducted to investigate the antioxidant and anti-lipoxygenase(LOX)properties of the isolated compound 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one from Pistacia chinensis.Methods:LOX assay and antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl(DPPH)assay were performed.Molecular docking studies were conducted using a molecular operating environment.Results:The LOX assay revealed significant inhibitory effects at 0.2µM concentration,with an IC50 value of 37.80µM.The antioxidant effect demonstrated dose-dependency across 5 to 100µg/mL concentrations,reaching 93.09%at 100µg/mL,comparable to ascorbic acid’s 95.43%effect.Molecular docking studies highlighted strong interactions with the lipoxygenase enzyme,presenting an excellent docking score of-10.98 kcal/mol.Conclusion:These findings provide valuable insights into Pistacia chinensis’chemical components and biological effects,reinforcing its traditional medicinal applications.

A Statistical Analysis on Papers and Authors in Wuhan University Journal of Natural Sciences in 2003

The author of this article counts and analyzes the papers and authors printed in 2003 Wuhan University Journal of Natural Sciences by means of bibliometric statistical methods, of which the characteristics of papers and authors are expounded. The result shows that the ratio of reprinting of this journal has been increased and the areas where the authors come from and their organization scattered in the whole world are widened as well, which implies a better-known fame of the journal. Key words Wuhan University Journal of Natural Sciences - papers analysis - authors analysis - statistical analysis CLC number G 353.1 Biography: HU Min(1961-), famale, Associate professor, research direction; editing science and biochemistry.

Critical Examination of the Suitability of the Folin-Ciocalteu Reagent Assay for Quantitative Analysis of Polyphenols—The Case of Olive-Mill Wastewater

The suitability of the Folin-Ciocalteu reagent (FCR) and of HPLC for analyzing polyphenols is evaluated. FCR assay is commonly used although its flows, such as overestimating polyphenol content due to interference by oxidizable species, were previously reported. The wide range of oxidizable species present in biological systems seriously compromises this assay’s reliability. Adding small amounts of protein to olive-mill wastewater (OMWW) significantly increased the apparent polyphenol content indicated by the FCR assay. The commonly used “reference” polyphenol as a standard for “total polyphenols” quantification is problematic since each polyphenol responds differently to the FCR. Conversely, HPLC may underestimate polyphenol content. No single HPLC protocol is likely to detect the whole myriad of polyphenols which may be present in a polyphenol-containing system. In analyzing 5 OMWW samples both by FCR assay and HPLC, the polyphenol content indicated by the FCR assay was up to six-fold higher than that determined by HPLC.

Determination of the diagnostic value of the resazurin reduction assay for evaluating boar semen by receiver operating characteristic analysis

Aim： To assess that metabolic status of spermatozoa could provide a useful tool for evaluation of semen quality. Methods： The accuracy of the spectrophotometric application of the resazurin reduction assay was assessed using receiver operating characteristic （ROC） analysis. Results： Areas under ROC curves （AUC） for motile sperm concentration and sperm index （SI） （sperm concentration multiplied by the square root of percentage sperm motility multiplied by the percentage normal sperm morphology） were 0.922. The best discrimination between poor and good semen samples according to the SI was achieved at a cut-off point of A610 = 0.209, where high sensitivity （94.1%） and specificity （91.7%） were calculated. The assay was less accurate when motile sperm concentration was used as the criterion value, yielding sensitivity of 88.2% and specificity of 87.5%, respectively. Likelihood ratios （LR） indicate that absorbances lower than 0.209 were at least 11.3 times as likely to be found in good semen samples than those in poor according to the SI, whereas in the case of motile sperm concentration, the LR was calculated to be 7.06. Conclusion： These results show that the resazurin reduction assay combined with spectrophotometry is an accurate method of assessing the quality of boar semen.

Published the papers of HPLC-MS analysis—Chemical drug

Sun Guoxiang, Ding Nan, Song Yuqing, Wang Zhen, Song Liangwei. Determination of Guaiacol salicylate in Guacetisal by HPLCmethod and qualitative identification of relevant substances by HPLC-MS

Published the papers of GC-MS analysis—Chemical drug

Song Qi, Liu Hu; Gao Shu. Screening and quantitative analysis of volatile markers in the breath of patients with breast cancer Acta Universitatis Medicinalis Anhui, 2010, 45（01） ：76-79.

Published the papers of HPLC-MS analysis—Traditional Chinese medicine

Medicinal materials Ma Chenchen, Li Bailin, Ou Jie, Wang Jing, Zhao Junhong. Detection of N-acyl-homoserine lactones class signal molecules of quorum sensing secreted by bacteria using high performance liquid chromatography-mass spectrometry/ mass spectrometry

Visualization analysis of the study of fund-sponsored clinical nursing papers

Objective： The aims of this study were to understand the status quo of authors, collaborations between institutions, research hotspots, and research frontiers of fund-sponsored clinical nursing papers and to provide a reference for Chinese scholars to conduct clinical nursing studies in the future.Methods： The visualization software CiteSpace was used to analyze fund-sponsored clinical nursing papers published between 2012 and 2016 in 12 core journals of nursing.Results： In the clinical nursing field, there are many co叩erative author groups; however, the collaborations between institu加 not close and exist mainly within the same province or city. High-frequency keywords have revealed the four clinical nursing research hotspots of population, diseases, nursing intervention, and others. Chinese medicine nursing, prevention, treatment and nursing, and new technology-aided nursing of ventilator-associated pneumonia are the study frontiers of clinical nursing.Conclusions： Clinical nursing studies are rich in content and cover a wide range of areas, and their hotspots and frontiers are closely related to the requirements of clinical nursing. Collaborations across regions, provinces, and cities are not adequate; there is an urgent need to strengthen the cross-regional exchanges and collaborations to promote the further development of clinical nursing.

Nonlinear Finite Element Analysis of Paper Movement in Air

In order to improve the office paper feeder design, and eliminate paper jam fault in running office equipment, the static deformation and dynamic response of paper were analyzed by use of the Finite Element Method (FEM). In the analysis, the three nodes mangle plate and shell element were employed, and finite element incremental formulations were derived on the basis of Updated Lagrangian (U.L) description. The newmark method was used to analyze the transient response of paper. All the results calculated in this article coincide with those by experiments.

Determination of the diagnostic value of the resazurin reduction assay for evaluating boar semen by receiver operating cha-racteristic analysis

Aim:To assess that metabolic status of spermatozoa could provide a useful tool for evaluation of semen quality. Methods:The accuracy of the spectrophotometric application of the resazurm reduction assay was assessed using receiver operating characteristic(ROC)analysis.Results:Areas under ROC curves(AUC)for motile sperm concen- tration and sperm index(SI)(sperm concentration multiplied by the square root of percentage sperm motility multi- plied by the percentage normal sperm morphology)were 0.922.The best discrimination between poor and good semen samples according to the SI was achieved at a cut-off point of A_(610)=0.209,where high sensitivity(94.1%)and specificity(91.7%)were calculated.The assay was less accurate when motile sperm concentration was used as the criterion value,vielding sensitivity of 88.2% and specificity of 87.5%,respectively,Likelihood ratios(LR)indicate that absorbances lower than 0.209 were at least 11.3 times as likely to be found in good semen samples than those in poor according to the SI,whereas in the case of motile sperm concentration,the LR was calculated to be 7.06.Conclusion: These results show that the resazurin reduction assay combined with spectrophotometry is an accurate method of assessing the quality of boar semen.

100 classic papers of interventional radiology: A citation analysis

AIM: To define the 100 citation classic papers of interventional radiology.METHODS: Using the database of Journal Citation Reports the 40 highest impact factor radiology journals were chosen. From these journals the 100 most cited interventional radiology papers were chosen and analysed.RESULTS: The top paper received 2497 citations and the 100 th paper 200 citations. The average number of citations was 320. Dates of publication ranged from 1953- 2005. Most papers originated in the United States(n = 67) followed by Italy(n = 20) and France(n = 10). Harvard University(n = 18) and Osped Civile(n = 11) were the most prolific institutions. Ten journals produced all of the top 100 papers with "Radiology" and "AJR" making up the majority. SN Goldberg and T Livraghi were the most prolific authors. Nearly two thirds of the papers(n = 61) were published after 1990.CONCLUSION: This analysis identifies many of the landmark interventional radiology papers and provides a fascinating insight into the changing discourse within the field. It also identifies topics, authors and institutions which have impacted greatly on the specialty.

Statistical Analysis for Test Papers with Software SPSS

Test paper evaluation is an important work for the management of tests,which results are significant bases for scientific summation of teaching and learning.Taking an English test paper of high students'monthly examination as the object,it focuses on the interpretation of SPSS output concerning item and whole quantitative analysis of papers.By analyzing and evaluating the papers,it can be a feedback for teachers to check the students'progress and adjust their teaching process.

Statistics and Analysis on Papers Published on Journal ‘Advanced Technology of Electrical Engineering and Energy’

The paper presented the statistics and analysis on papers published on the journal 'Advanced Technology of Electrical Engineering and Energy' from 1996 to 2008: the paper acceptance rate,the paper category,the first author's affiliations,the top 7 first authors,the top 10 coauthors and also the journal evaluation indexes of the journal.It offers details of the journal to anyone interested,especially to our editorial board and our broad readers.

Econometric Analysis of Research Papers on the Project of " Turning Vulnerable Farmland into Forests "

Taking the Database of Chinese Scientific and Technical Periodicals of Chongqing VIP Information Co. ,Ltd. as the statistical analysis source,we analyze the inter-annual trends,the authors institutions,journals distribution,disciplines distribution,paper subjects and authors' cooperation of research papers on the project of " turning vulnerable farmland into forests" in China during the period 1999 -2010,using the bibliometric method. The results show that during the period 1999 -2010,the research on the project of " turning vulnerable farmland into forests" always captured the attention of academia,and the number of research papers annually averaged more than 300; the relevant forestry functional departments at all levels,forestry-related research institutions and universities have paid close attention to the project of " turning vulnerable farmland into forests" in China; the group of core journals researched is concentrated in journals concerning forestry; in addition to forestry and agriculture,the research areas also touch upon economics,environment and other disciplines; the emphasis and hot spot of research are centered on applications, with few basic researches.

Intelligent Diagnostic Method for Ageing Analysis of Transformer

The fuzzy method is proposed for ageing analysis of transformer. The fuzzy controller is used for various input and one output, strictly depends on the number of membership function and there rule base and the type of the defuzzification method. The ageing of transformers is influenced by short term and long term over loads, number and intensity of short circuits, incidence of lightning, and internal faults. The recent development of various techniques for detecting the incipient fault conditions have been improved to some extent;the life expectancy of transformers by resorting to corrective actions in time. The ageing behavior is likely to be different for different types of transformers. The life span of the transformer, thus depends initially on the design and quality of manufacture and later on service conditions and maintenance standard, these factors vary considerably and affect the useful span of service life which therefore needs to be taken into account for residual life assessment. During the natural ageing of transformers, the insulation of winding deteriorates. Cellulose insulation degrades due to heating or electrical breakdown which is dissolved in oil. Hence, the chemical analysis of the Transformer oil gives evidence of changes that are taking place in the winding insulation during operation. Deterioration in transformer cellulose decreases both its electrical and mechanical strength. In this paper a novel fuzzy based algorithm has been implemented on three samples of power transformer oil.

Phytochemical Analysis and Antioxidant Activity Determination on Crude Extracts of <i>Melodinus eugeniifolus</i>Barks and Leaves from Malaysia

Six different extracts of Melodinus eugeniifolus (a very rare medical plant belonging to Apocynaceae) leaves and barks were screened for their phytochemical composition, and free radical scavenging activities. Three different methods were used to test the antioxidant activity for extracts which include FRAP assay (Ferric reducing antioxidant potential), DPPH radical scavenging assay (1,1-diphenyl-2-picryl hydrazyl radical reducing power methods), and β-carotene bleaching assay. Among the different extracts tested, the ethanol extract of barks showed significant radical scavenging activities. Phytochemical analysis of the extracts revealed that the radical scavenging activities are mainly due to the presence of alkaloids, cardiac glycosides, sterols, steroids and flavonoids. The results obtained suggest that Melodinus eugeniifolus could be exploited in the management of various diseases like cancer, cardiovascular diseases and infection diseases. Highlights: Melodinus eugeniifolus, a very rare medical plant from South Asian rain forest which may be a potential drug for many diseases is first reported about its phytochemical characteristics and antioxidant activity by different methods.

Arc-length technique for nonlinear finite element analysis

Nonlinear solution of reinforced concrete structures, particularly complete load-deflection response, requires tracing of the equilibrium path and proper treatment of the limit and bifurcation points. In this regard, ordinary solution techniques lead to instability near the limit points and also have problems in case of snap-through and snap-back. Thus they fail to predict the complete load-displacement response. The arc-length method serves the purpose well in principle, received wide acceptance in finite element analysis, and has been used extensively. However modifications to the basic idea are vital to meet the particular needs of the analysis. This paper reviews some of the recent developments of the method in the last two decades, with particular emphasis on nonlinear finite element analysis of reinforced concrete structures.

Aspect-based sentiment analysis of online peer reviews and prediction of paper acceptance results

Peer reviews of academic articles contain reviewers’ overall impressions and specific comments on the contributed articles,which have a lot of sentimental information.By exploring the fine-grained sentiments in peer reviews,we can discover critical aspects of interest to the reviewers.The results can also assist editors and chairmen in making final decisions.However,current research on the aspects of peer reviews is coarse-grained,and mostly focuses on the overall evaluation of the review objects.Therefore,this paper constructs a multi-level fine-grained aspect set of peer reviews for further study.First,this paper uses the multi-level aspect extraction method to extract the aspects from peer reviews of ICLR conference papers.Comparative experiments confirm the validity of the method.Secondly,various Deep Learning models are used to classify aspects’ sentiments automatically,with LCFS-BERT performing best.By calculating the correlation between sentimental scores of the review aspects and the acceptance result of papers,we can find the important aspects affecting acceptance.Finally,this paper predicts acceptance results of papers(accepted/rejected) according to the peer reviews.The optimal acceptance prediction model is XGboost,achieving a Macro_F1 score of 87.43%.

Analysis of rice paper's morphological features based on multispectral imaging technology

Computer forensics and identification for traditional Chinese painting arts have caught the attention of various fields. Rice paper＇s feature extraction and analysis methods are of high significance for the rice paper is an important carrier of traditional Chinese painting arts. In this paper, rice paper＇s morphological feature analysis is done using multi spectral imaging technology. The multispectral imaging system is utilized to acquire rice paper＇s spectral images in different wave- length channels, and then those spectral images are measured using texture parameter statistics to acquire sensitive bands for rice paper＇s feature. The mathematical morphology and grayscale statistical principle are utilized to establish a rice paper＇s morphological feature analytical model which is used to acquire rice paper＇ s one-dimensional vector. For the purpose of eval- uating these feature vectors＇ accuracy, they are entered into the support vector machine（SVM） classifier for detection and classification. The results show that the rice paper＇s feature is out loud in the spectral band 550 nm, and the average classifi- cation accuracy of feature vectors output from the analytical model is 96 %. The results indicate that the rice paper＇s feature analytical model can extract most of rice paper＇s features with accuracy and efficiency.

Exploring the intellectual structure based on co-citation network analysis: A case study of diabetes

As the number of diabetics increases worldwide,the amount of research so as to bibliometric re-search on diabetes is also growing.In order to review the existing research on diabetes from a macro perspective and to remedy the lack of attention given to conference papers,this paper collected a total of 67,104 diabetes-related conference papers on the theme of"diabetes"up to 23 October 2020 in the core collection of Web of Science.Tools for bibliometric analysis include Citespace and vosviewer and other tools such as Excel and Origin are applied for statistical analysis and visualization of the results.Consequently,publication trend,document co-citation,journal co-citation and author co-citation are analyzed based on these papers,and core docu-ments,journals and authors are identified.This study not only shows the current situation of a-cademic conferences related to diabetes research but also,to a certain extent,reveals the devel-opment of the diabetes research situation in the whole field.Meanwhile,this study quantitatively analyzed the intellectual base on diabetes,which can be an illustration of the benefits of biblio-metric analysis as a tool in scientific research.