In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dyn...In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dynamics(MD)methods were adopted as a means to simulate particle motion.Modified attachment energy(MAE)model was employed to calculate the growth morphology of TKX-50.The simulation results demonstrate that COMPASS force field and RESP charge are suitable for molecular dynamics simulation of TKX-50.The morphologically dominant growth surfaces of TKX-50 in vacuum are(020),(011),(11–1),(100)and(120),respectively.In water(H_(2)O)and N,N-dimethylformamide(DMF)solvents,the(11–1)face is the largest in the habit face,the growth rate of(020)face becomes faster.With the increase of temperature,the aspect ratios of TKX-50 crystal in DMF solvent increase,and the areas of the(120)faces decrease.In ethylene glycol/H_(2)O mixed solvent system with volume ratio of 1/1,aspect ratio of TKX-50 is relatively small.In formic acid/H_(2)O mixed solvents with different volume ratios(1/4,1/3,1/2,1/1 and 2/1),aspect ratio of TKX-50 is relatively small when volume ratio is 1/2.展开更多
Objective:To compare the effect of human chorionic gonadotropin(hCG)-producing peripheral blood mononuclear cells(PBMCs)and PBMCs activated by hCG in vitro and expressions of related immune genes in mouse implantation...Objective:To compare the effect of human chorionic gonadotropin(hCG)-producing peripheral blood mononuclear cells(PBMCs)and PBMCs activated by hCG in vitro and expressions of related immune genes in mouse implantation.Methods:hCG-producing PBMCs(transfected PBMC)and PBMCs activated by hCG in vitro were introduced into isolated mouse endometrial cells,while cell cultures were divided into four groups:the control,PBMC,transfected,and activated PBMC groups.The expression of studied genes(IL-1β,IL-6,Lif,and Vegf)was evaluated and blastocyst attachment on the cocultured cells(isolated endometrial cells and PBMC cells)was monitored in all four groups.Results:Data showed that expression decreased in the PBMC group compared to the treated PBMC(transfected and activated PBMCs)and increased in transfected PBMC compared to the activated PBMC.Attachment and migration of blastocysts were dramatically enhanced in the transfected PBMC group compared to the activated PBMC group(P<0.05).Conclusions:Use of hCG-producing PBMCs(transfected PBMC)has more influence on endometrial receptivity.展开更多
The implementation of China’s three-child fertility policy has led to a notable increase in multiple-child families.Notably,firstborn children experience a significant transition from being an only child to a non-only ...The implementation of China’s three-child fertility policy has led to a notable increase in multiple-child families.Notably,firstborn children experience a significant transition from being an only child to a non-only child.This transition is associated with problematic behaviors,affecting their social adjustment,sibling relationships,and family harmony.Although several studies have examined the relationship between parent-child attachment and problem behaviors exhibited byfirstborn children during family transitions,thefindings have been inconsistent.Hence,a meta-analytic study was undertaken to elucidate the inconsistencies in this relationship and explore the moderating factors that may contribute to these discrepancies.Using a systematic literature retrieval and screening method,12 effect sizes were derived from the 10 eligible articles,encompassing a sample size of 5319.The meta-analysis demonstrated a low negative association between parent-child secure attachment and problem behaviors exhibited byfirstborn children during family transitions.Furthermore,the present study investigates potential moderator factors,such as children’s age and geographic region,to gain a more nuanced understanding of the relationship.Consequently,the establishment of parent-child attachment relationships has the potential to mitigate problem behaviors observed infirst-born children during family transitions.The implications of thesefindings indicate that parents can nurture secure attachment bonds with their children by demonstrating sensitive responsiveness,employing positive parenting practices,and fostering emotional availability.These efforts contribute to the cultivation of secure internal working models and positive behavioral manifestations withinfirst-born children,which in turn affect their relationships with siblings.展开更多
On the basis of combing the relevant theories of place attachment, the planning framework of upgrading and reconstruction of old parks based on place attachment was put forward. Taking Nanchang Bayi Park as an example...On the basis of combing the relevant theories of place attachment, the planning framework of upgrading and reconstruction of old parks based on place attachment was put forward. Taking Nanchang Bayi Park as an example, the methods and key points of landscape improvement and transformation of old urban parks based on place attachment were explained to provide new ways and references for the renewal of old urban parks.展开更多
The bipartite graph structure exists in the connections of many objects in the real world, and the evolving modeling is a good method to describe and understand the generation and evolution within various real complex...The bipartite graph structure exists in the connections of many objects in the real world, and the evolving modeling is a good method to describe and understand the generation and evolution within various real complex networks. Previous bipartite models were proposed to mostly explain the principle of attachments, and ignored the diverse growth speed of nodes of sets in different bipartite networks. In this paper, we propose an evolving bipartite network model with adjustable node scale and hybrid attachment mechanisms, which uses different probability parameters to control the scale of two disjoint sets of nodes and the preference strength of hybrid attachment respectively. The results show that the degree distribution of single set in the proposed model follows a shifted power-law distribution when parameter r and s are not equal to 0, or exponential distribution when r or s is equal to 0. Furthermore, we extend the previous model to a semi-bipartite network model, which embeds more user association information into the internal network, so that the model is capable of carrying and revealing more deep information of each user in the network. The simulation results of two models are in good agreement with the empirical data, which verifies that the models have a good performance on real networks from the perspective of degree distribution. We believe these two models are valuable for an explanation of the origin and growth of bipartite systems that truly exist.展开更多
基金supported by Fundamental Research Program of Shanxi Province(20210302123055)and(201801D221035).
文摘In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dynamics(MD)methods were adopted as a means to simulate particle motion.Modified attachment energy(MAE)model was employed to calculate the growth morphology of TKX-50.The simulation results demonstrate that COMPASS force field and RESP charge are suitable for molecular dynamics simulation of TKX-50.The morphologically dominant growth surfaces of TKX-50 in vacuum are(020),(011),(11–1),(100)and(120),respectively.In water(H_(2)O)and N,N-dimethylformamide(DMF)solvents,the(11–1)face is the largest in the habit face,the growth rate of(020)face becomes faster.With the increase of temperature,the aspect ratios of TKX-50 crystal in DMF solvent increase,and the areas of the(120)faces decrease.In ethylene glycol/H_(2)O mixed solvent system with volume ratio of 1/1,aspect ratio of TKX-50 is relatively small.In formic acid/H_(2)O mixed solvents with different volume ratios(1/4,1/3,1/2,1/1 and 2/1),aspect ratio of TKX-50 is relatively small when volume ratio is 1/2.
文摘Objective:To compare the effect of human chorionic gonadotropin(hCG)-producing peripheral blood mononuclear cells(PBMCs)and PBMCs activated by hCG in vitro and expressions of related immune genes in mouse implantation.Methods:hCG-producing PBMCs(transfected PBMC)and PBMCs activated by hCG in vitro were introduced into isolated mouse endometrial cells,while cell cultures were divided into four groups:the control,PBMC,transfected,and activated PBMC groups.The expression of studied genes(IL-1β,IL-6,Lif,and Vegf)was evaluated and blastocyst attachment on the cocultured cells(isolated endometrial cells and PBMC cells)was monitored in all four groups.Results:Data showed that expression decreased in the PBMC group compared to the treated PBMC(transfected and activated PBMCs)and increased in transfected PBMC compared to the activated PBMC.Attachment and migration of blastocysts were dramatically enhanced in the transfected PBMC group compared to the activated PBMC group(P<0.05).Conclusions:Use of hCG-producing PBMCs(transfected PBMC)has more influence on endometrial receptivity.
基金Funding of this research work is generously supported by the University Malaya Community Campus Grant-RUU2022-LL016Private Grant PV086-2022(University Poly-Tech MARA-UPTM),Kuala LumpurUniversitas Negeri Malang,Indonesia.
文摘The implementation of China’s three-child fertility policy has led to a notable increase in multiple-child families.Notably,firstborn children experience a significant transition from being an only child to a non-only child.This transition is associated with problematic behaviors,affecting their social adjustment,sibling relationships,and family harmony.Although several studies have examined the relationship between parent-child attachment and problem behaviors exhibited byfirstborn children during family transitions,thefindings have been inconsistent.Hence,a meta-analytic study was undertaken to elucidate the inconsistencies in this relationship and explore the moderating factors that may contribute to these discrepancies.Using a systematic literature retrieval and screening method,12 effect sizes were derived from the 10 eligible articles,encompassing a sample size of 5319.The meta-analysis demonstrated a low negative association between parent-child secure attachment and problem behaviors exhibited byfirstborn children during family transitions.Furthermore,the present study investigates potential moderator factors,such as children’s age and geographic region,to gain a more nuanced understanding of the relationship.Consequently,the establishment of parent-child attachment relationships has the potential to mitigate problem behaviors observed infirst-born children during family transitions.The implications of thesefindings indicate that parents can nurture secure attachment bonds with their children by demonstrating sensitive responsiveness,employing positive parenting practices,and fostering emotional availability.These efforts contribute to the cultivation of secure internal working models and positive behavioral manifestations withinfirst-born children,which in turn affect their relationships with siblings.
基金Supported by the Social Science Foundation of Jiangxi Province (22GL10)National Natural Science Foundation of China (32001366)+1 种基金General Project of China Postdoctoral Science Foundation (2022M710403)Humanities and Social Sciences Research Project of Colleges and Universities of Jiangxi Province(JC21103)。
文摘On the basis of combing the relevant theories of place attachment, the planning framework of upgrading and reconstruction of old parks based on place attachment was put forward. Taking Nanchang Bayi Park as an example, the methods and key points of landscape improvement and transformation of old urban parks based on place attachment were explained to provide new ways and references for the renewal of old urban parks.
文摘The bipartite graph structure exists in the connections of many objects in the real world, and the evolving modeling is a good method to describe and understand the generation and evolution within various real complex networks. Previous bipartite models were proposed to mostly explain the principle of attachments, and ignored the diverse growth speed of nodes of sets in different bipartite networks. In this paper, we propose an evolving bipartite network model with adjustable node scale and hybrid attachment mechanisms, which uses different probability parameters to control the scale of two disjoint sets of nodes and the preference strength of hybrid attachment respectively. The results show that the degree distribution of single set in the proposed model follows a shifted power-law distribution when parameter r and s are not equal to 0, or exponential distribution when r or s is equal to 0. Furthermore, we extend the previous model to a semi-bipartite network model, which embeds more user association information into the internal network, so that the model is capable of carrying and revealing more deep information of each user in the network. The simulation results of two models are in good agreement with the empirical data, which verifies that the models have a good performance on real networks from the perspective of degree distribution. We believe these two models are valuable for an explanation of the origin and growth of bipartite systems that truly exist.