BACKGROUND Acute stress might increase short-term heart rate variability and blood pressure variability(BPV);however,chronic stress would not alter short-term BPV in animal models.AIM To examine the association of psy...BACKGROUND Acute stress might increase short-term heart rate variability and blood pressure variability(BPV);however,chronic stress would not alter short-term BPV in animal models.AIM To examine the association of psychological stress with long-term BPV in young male humans.METHODS We prospectively examined the association of chronic psychological stress with long-term BPV in 1112 healthy military males,averaged 32.2 years from the cardiorespiratory fitness and hospitalization events in armed forces study in Taiwan.Psychological stress was quantitatively evaluated with the Brief Symptom Rating Scale(BSRS-5),from the least symptom of 0 to the most severe of 20,and the five components of anxiety,insomnia,depression,interpersonal sensitivity,and hostility(the severity score in each component from 0 to 4).Longterm BPV was assessed by standard deviation(SD)for systolic and diastolic blood pressure(SBP and DBP),and average real variability(ARV),defined as the average absolute difference between successive measurements of SBP or DBP,across four visits in the study period from 2012 to 2018(2012-14,2014-15,2015-16,and 2016-18).RESULTS The results of multivariable linear regressions showed that there were no correlations of the BSRS-5 score with SDSBP,SDDBP,ARVSBP,and ARVDBP after adjusting for all the covariates[β(SE):-0.022(0.024),-0.023(0.026),-0.001(0.018),and 0.001(0.020),respectively;P>0.05 for all].In addition,there were also no correlations between each component of the BSRS score and the long-term BPV indexes.CONCLUSION Our findings suggest that chronic psychological stress might not be associated with long-term BPV in military young male humans.展开更多
目的应用倾向性评分匹配法前瞻性分析脑氧饱和度平均真实变异度(average real variability,ARV)对高龄胃肠道肿瘤手术患者术后心肌损伤发生率的影响。方法选取择期全麻下行腹腔镜胃肠道恶性肿瘤根治术老年患者104例,男73例,女31例,年龄6...目的应用倾向性评分匹配法前瞻性分析脑氧饱和度平均真实变异度(average real variability,ARV)对高龄胃肠道肿瘤手术患者术后心肌损伤发生率的影响。方法选取择期全麻下行腹腔镜胃肠道恶性肿瘤根治术老年患者104例,男73例,女31例,年龄65~80岁,ASAⅡ或Ⅲ级,BMI 18~30 kg/m^(2)。根据术中脑氧饱和度ARV中位数分为两组:高ARV组(A组,n=53)和低ARV组(B组,n=51)。应用倾向性评分匹配以均衡组间协变量,比较两组术后心肌损伤及心电图发生缺血性改变的发生率。结果两组间BMI、术中麻黄素使用率、术中rSO_(2)最大值、最小值以及差值的差异有统计学意义(P<0.05)。经倾向性评分匹配,选用最近邻匹配法,设置卡钳值为0.2,两组按照1∶1进行匹配,成功匹配各32例。A组心肌损伤发生率高于B组(18.75%vs.3.125%,P<0.05),A组心电图发生缺血性改变发生率与B组比较差异无统计学意义(9.375%vs.3.125%,P>0.05)。结论术中低脑氧饱和度变异度有助于降低高龄胃肠肿瘤手术患者术后心肌损伤的发生率,提高围术期安全性。展开更多
基金the Hualien Armed Forces General Hospital Grant,No.HAFGH-D-109007.
文摘BACKGROUND Acute stress might increase short-term heart rate variability and blood pressure variability(BPV);however,chronic stress would not alter short-term BPV in animal models.AIM To examine the association of psychological stress with long-term BPV in young male humans.METHODS We prospectively examined the association of chronic psychological stress with long-term BPV in 1112 healthy military males,averaged 32.2 years from the cardiorespiratory fitness and hospitalization events in armed forces study in Taiwan.Psychological stress was quantitatively evaluated with the Brief Symptom Rating Scale(BSRS-5),from the least symptom of 0 to the most severe of 20,and the five components of anxiety,insomnia,depression,interpersonal sensitivity,and hostility(the severity score in each component from 0 to 4).Longterm BPV was assessed by standard deviation(SD)for systolic and diastolic blood pressure(SBP and DBP),and average real variability(ARV),defined as the average absolute difference between successive measurements of SBP or DBP,across four visits in the study period from 2012 to 2018(2012-14,2014-15,2015-16,and 2016-18).RESULTS The results of multivariable linear regressions showed that there were no correlations of the BSRS-5 score with SDSBP,SDDBP,ARVSBP,and ARVDBP after adjusting for all the covariates[β(SE):-0.022(0.024),-0.023(0.026),-0.001(0.018),and 0.001(0.020),respectively;P>0.05 for all].In addition,there were also no correlations between each component of the BSRS score and the long-term BPV indexes.CONCLUSION Our findings suggest that chronic psychological stress might not be associated with long-term BPV in military young male humans.
文摘目的应用倾向性评分匹配法前瞻性分析脑氧饱和度平均真实变异度(average real variability,ARV)对高龄胃肠道肿瘤手术患者术后心肌损伤发生率的影响。方法选取择期全麻下行腹腔镜胃肠道恶性肿瘤根治术老年患者104例,男73例,女31例,年龄65~80岁,ASAⅡ或Ⅲ级,BMI 18~30 kg/m^(2)。根据术中脑氧饱和度ARV中位数分为两组:高ARV组(A组,n=53)和低ARV组(B组,n=51)。应用倾向性评分匹配以均衡组间协变量,比较两组术后心肌损伤及心电图发生缺血性改变的发生率。结果两组间BMI、术中麻黄素使用率、术中rSO_(2)最大值、最小值以及差值的差异有统计学意义(P<0.05)。经倾向性评分匹配,选用最近邻匹配法,设置卡钳值为0.2,两组按照1∶1进行匹配,成功匹配各32例。A组心肌损伤发生率高于B组(18.75%vs.3.125%,P<0.05),A组心电图发生缺血性改变发生率与B组比较差异无统计学意义(9.375%vs.3.125%,P>0.05)。结论术中低脑氧饱和度变异度有助于降低高龄胃肠肿瘤手术患者术后心肌损伤的发生率,提高围术期安全性。
