The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adapt...The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adaptions is thought to contribute to disruptions of emotion regulation, motivation and cognitive abilities that underlie postpartum mental disorders, such as postpartum depression. Despite the high incidence of this disorder, and the detrimental consequences for both mother and child, its etiology and related neurobiological mechanisms remain poorly understood, partially due to the lack of appropriate animal models. In recent decades, there have been a number of attempts to model postpartum depression disorder in rats. In the present review, we first describe clinical symptoms of postpartum depression and discuss known risk factors, including both genetic and environmental factors. Thereafter, we discuss various rat models that have been developed to capture various aspects of this disorder and knowledge gained from such attempts. In doing so, we focus on the theories behind each attempt and the methods used to achieve their goals. Finally, we point out several understudied areas in this field and make suggestions for future directions.展开更多
The effects of the nuclear current in the antimagnetic rotation band of 105Cd have been investigated in a fully self-consistent and microscopic way by using the tilted axis cranking relativistic mean-field model.It wa...The effects of the nuclear current in the antimagnetic rotation band of 105Cd have been investigated in a fully self-consistent and microscopic way by using the tilted axis cranking relativistic mean-field model.It was found that the inclusion of nuclear current leads to a higher angular momentum and thus a larger kinetic moment of inertia at a given rotational frequency.As a consequence,the B(E2) values with current are always smaller than those without current.展开更多
基金Foundation items： The preparation of this review was partially supported by a grant from the National Institute of Mental Health （5R01 MH097718-02）, U.S.A.
文摘The postpartum period is when a host of changes occur at molecular, cellular, physiological and behavioral levels to prepare female humans for the challenge of maternity. Alteration or prevention of these normal adaptions is thought to contribute to disruptions of emotion regulation, motivation and cognitive abilities that underlie postpartum mental disorders, such as postpartum depression. Despite the high incidence of this disorder, and the detrimental consequences for both mother and child, its etiology and related neurobiological mechanisms remain poorly understood, partially due to the lack of appropriate animal models. In recent decades, there have been a number of attempts to model postpartum depression disorder in rats. In the present review, we first describe clinical symptoms of postpartum depression and discuss known risk factors, including both genetic and environmental factors. Thereafter, we discuss various rat models that have been developed to capture various aspects of this disorder and knowledge gained from such attempts. In doing so, we focus on the theories behind each attempt and the methods used to achieve their goals. Finally, we point out several understudied areas in this field and make suggestions for future directions.
基金supported by the National Basic Research Program of China(Grant No.2007CB815000)the National Natural Science Foundation of China(Grant Nos.10975008, 11105005 and 11175002)the Research Fund for the Doctoral Program of Higher Education(Grant No.20110001110087)
文摘The effects of the nuclear current in the antimagnetic rotation band of 105Cd have been investigated in a fully self-consistent and microscopic way by using the tilted axis cranking relativistic mean-field model.It was found that the inclusion of nuclear current leads to a higher angular momentum and thus a larger kinetic moment of inertia at a given rotational frequency.As a consequence,the B(E2) values with current are always smaller than those without current.
